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A Preliminary Study Of A Non Invasive Glucose Sensor Based On A Mercury Sensor
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Book Synopsis A Preliminary Study of a Non-invasive Glucose Sensor Based on a Mercury Sensor by : Erin Leigh Wood
Download or read book A Preliminary Study of a Non-invasive Glucose Sensor Based on a Mercury Sensor written by Erin Leigh Wood and published by . This book was released on 2009 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a potentially lethal disease that affects 7.6 percent of American people. In the US, it is recognized as the 6th leading cause of death. Failure to control blood glucose levels (BGL) in patients with either type of diabetes can lead to other serious complications as well, such as loss of limb, blindness and other health problems. Controlling and monitoring the BGL in post-op and intensive care patients in the hospital is also vital to their health. Currently the most reliable method of monitoring BGL is through an invasive procedure which monitors the amount of glucose in blood directly. A non-invasive glucose sensor would drastically improve the treatment of sensitive patients, and serve to improve the quality of diabetic patients' lives. This glucose sensor is strongly based upon the mercury sensor developed by F.E. Hernandez and his colleagues. Glucose is used as a reducing agent to reduce mercury from Hg2+ to Hg0, which will form amalgams with the gold nanorods in solution. The change in aspect ratio of gold nanorods leads to a change in the UV-Visible spectrum of the solution. The blue shift seen was measured and correlated with the glucose concentration of the system. The system was then tested varying conditions such as pH, temperature, gold nanorod concentration, and mercury concentration. A preliminary study of the kinetics of the reaction was also done. The results showed a limit of detection of 1.58x10−13 and a linear dynamic range covering the concentrations of human tear glucose levels that are currently cited in the literature.
Book Synopsis Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions by : Carlos G. Juan
Download or read book Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions written by Carlos G. Juan and published by Springer Nature. This book was released on 2021-06-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive study covering the design and application of microwave sensors for glucose concentration detection, with a special focus on glucose concentration tracking in watery and biological solutions. This book is based on the idea that changes in the glucose concentration provoke variations in the dielectric permittivity of the medium. Sensors whose electrical response is sensitive to the dielectric permittivity of the surrounding media should be able to perform as glucose concentration trackers. At first, this book offers an in-depth study of the dielectric permittivity of water–glucose solutions at concentrations relevant for diabetes purposes; in turn, it presents guidelines for designing suitable microwave resonators, which are then tested in both water–glucose solutions and multi-component human blood plasma solutions for their detection ability and sensitivities. Finally, a portable version is developed and tested on a large number of individuals in a real clinical scenario. All in all, the book reports on a comprehensive study on glucose monitoring devices based on microwave sensors. It covers in depth the theoretical background, provides extensive design guidelines to maximize sensitivity, and validates a portable device for applications in clinical settings.
Book Synopsis Glucose Level Estimation Based on Invasive Electrochemical, and Non-invasive Optical Sensing Methods by : Sanghamitra Mandal
Download or read book Glucose Level Estimation Based on Invasive Electrochemical, and Non-invasive Optical Sensing Methods written by Sanghamitra Mandal and published by . This book was released on 2018 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this research is to design and fabricate sensors for glucose detection using inexpensive approaches. My first research approach is the fabrication of an amperometric electrochemical glucose sensor, by exploiting the optical properties of semiconductors and structural properties of nanostructures, to enhance the sensor sensitivity and response time. Enzymatic electrochemical sensors are fabricated using two different mechanisms: (1) the low-temperature hydrothermal synthesis of zinc oxide nanorods, and (2) the rapid metal-assisted chemical etching of silicon (Si) to synthesize Si nanowires. The concept of gold nano-electrode ensembles is then employed to the sensors in order to boost the current sensitivities by enhancing the rate of electron transfer during the electrochemical reaction. High crystallinity and good alignment of the nanostructures lead to increase in the electrode surface area, thereby leading to higher current sensitivities compared to other published works. My second research approach is to design an optical sensor for evaluating long-term glycemic state in diabetic patients. Glycated hemoglobin (HbA1c) is a minor component of blood hemoglobin to which glucose is bound. The HbA1c test is a common medical test used to indicate the average blood glucose level over the past 12-16 weeks. The National Institute of Diabetes and Digestive and Kidney Diseases has established a direct relationship between the percentage of HbA1c and the blood sugar level. Our sensor instrumentation design is based on the Beer's law of optical absorption. Major device components include two commercial light emitting diodes, a cuvette holder, a Si photodiode, and an ATmega328P microcontroller. It is observed that the absorbance of diluted HbA1c samples and the corresponding photodiode output voltage are inversely related. The photodiode voltages as a function of HbA1c percentage concentrations show an exponentially decaying curve. An algorithm for multiple variable regression analysis is then used for sensor calibration. The percentage of HbA1c is then anticipated based on the obtained output voltage using the calibrated curve results. The proposed portable optical sensor proves to be a promising step towards the prediction of the long-term glycemic levels in diabetic and pre-diabetic patients non-invasively.
Book Synopsis A Wearable 1.6GHz Non-Invasive Midfield Wave-Based Blood Glucose Sensor by : Danielle Nishida
Download or read book A Wearable 1.6GHz Non-Invasive Midfield Wave-Based Blood Glucose Sensor written by Danielle Nishida and published by . This book was released on 2015 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: A non-invasive glucose sensor has been sought after by millions of Americans living with diabetes and scientists alike. Current blood glucose sensors approved by the FDA involve an invasive collection technique coupled with costly chemical analysis materials, which continue to bring pain to the growing diabetic population in America. Previous research of non-invasive sensing methods has shown promise, but the difficulty of transmitting power through tissue has degraded the sensing consistency and accuracy needed to reach the consumer market. This has been overcome with recent research in midfield wave power transmission at Stanford University, which has provided an opportunity for investigating a new, non-invasive glucose sensing technique. The design proposed in this thesis uses a slot array antenna transmitting through the human arm in the UHF (Ultra High Frequency) range at a wavelength absorbed by glucose to investigate the relationship between blood glucose levels and received power from a loop antenna receiver. The complete system incorporates an RF mixer, a Wilkinson power divider, and an RF detector to enable use with Cal Poly’s lab equipment. Changes in blood glucose levels are tracked within an R value of 0.91 when the testing setup maintains consistency in physical placement of the transmitter and receiver. Ten measurements over the course of seven hours accurately sensed changes in the subject’s blood glucose levels with two outlier data points. The system provides a vehicle for further investigation into a new, non-invasive blood glucose sensing method to improve the quality of life for millions around the world.
Book Synopsis Truly Non Invasive Glucose Optical Sensor Based on Metal Nanoparticles Generation by : Marisol Garcia
Download or read book Truly Non Invasive Glucose Optical Sensor Based on Metal Nanoparticles Generation written by Marisol Garcia and published by . This book was released on 2006 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is a disease that causes many complications in human normal function. This disease represents the sixth-leading cause of death in USA. Prevention of diabetes-related complications can be accomplished through tight control of glucose levels in blood. In the last decades many different glucose sensors have been developed, however, none of them are really non invasive. Herein, we present the study of the application of gold and silver nanoparticles with different shapes and aspect ratios to detect glucose traces in human fluids such as tears and sweat. This is to our knowledge the first truly non invasive glucose optical sensor, with extraordinary limit of detection and selectivity. The best proven nanoparticles for this application were gold nanospheres. Gold nanospheres were synthesized using chloroauric acid tri-hydrated (HAuCl4.3H2O) in solution, in the presence of glucose and ammonia hydroxide. The higher the glucose concentration, the higher the number of nanoparticles generated, thus the higher the extinction efficiency of the solution. The linear dependence of the extinction efficiency of the gold nanoparticles solution with glucose concentration makes of this new sensor suitable for direct applications in biomedical sensing. Our approach is based on the well known Tollens test.
Book Synopsis Development of Non-invasive Glucose Sensor by : Shiva Prasad Cheggoju
Download or read book Development of Non-invasive Glucose Sensor written by Shiva Prasad Cheggoju and published by . This book was released on 2016 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: A sensor for measuring body glucose concentration non-invasively was designed. This non-invasive sensor is an inductor with plastic material as its core having permeability nearly equal to that of air. The proposed sensor is examined by placing it on the body usually on wrist or arm and the obtained results are analyzed to know the change in glucose concentration. The working principle of the sensor is that the stray capacitance present between the turns of the inductor varies with the change in body glucose because the change in glucose levels changes the dielectric properties of the tissue and as the sensor is on the body, it senses these changes in dielectric properties. The circuit model of the sensor is simulated to analyze its electrical characteristics and the observed results are provided in this work. A prototype of the sensor is built and several tests are conducted on body and even on sugar solutions of different concentrations. A detection circuit is built which includes amplitude and phase detectors to measure the variations of sensor output. With the analysis of body test results, the sensor seems to sense the change in body glucose concentration before and after the meals which is observed as a change in the voltage of the detection circuit.
Book Synopsis Non-enzymatic Glucose Sensors Based on Laser-induced Graphene Integrated with Skin-interfaced Microfluidic Component for On-body Measurement by : Shangbin Liu
Download or read book Non-enzymatic Glucose Sensors Based on Laser-induced Graphene Integrated with Skin-interfaced Microfluidic Component for On-body Measurement written by Shangbin Liu and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent increased interest in wearable and mobile technologies has prompted increasing research efforts in developing non-invasive glucose monitoring platforms. In comparison with enzymatic glucose sensors, non-enzymatic glucose sensors have low cost, high stability, and easy integration and have the potential to be wearable real-time monitoring sensors. However, due to the trace amount of glucose in sweat, the sensitivity of existing non-enzymatic glucose sensors still needs to be further improved. To demonstrate practical approaches with bimetals or 3D porous structures, the porous laser-induced graphene (LIG) on flexible polymers demonstrates good conductivity and a simple fabrication process to integrate sensing materials. The uniform electroless plating of the nickel and gold layer on LIG electrodes demonstrates significantly enhanced sensitivity and an extensive linear range for glucose sensing. The sensor with the porous LIG foam exhibits a high sensitivity of 1080 [mu]A·mM-1·cm-2 , whereas a further increased sensitivity of 3500 [mu]A·mM-1·cm-2 is obtained with LIG fibers (LIGF). Impressively, a significant linear range (0--30 mM) can be achieved by changing the bias voltage from 0.5 to 0.1 V due to the Au coating. In order to store and evaluate the sweat content of sweat on the skin, this work integrates a porous encapsulated reaction chamber with an alkaline solution containing an alkaline solution with a soft, skin-interface microfluidic component. In addition, we tested glucose levels in human sweat and cell culture media before and after meals using the amperometric response of the sensor that demonstrates non-enzymatic sweat glucose biosensors are expected to be the prospect of commercial wearable devices.
Book Synopsis Preliminary Investigation of an Implantable Blood Glucose Sensor for Diabetic Patients by : David A. Villarreal
Download or read book Preliminary Investigation of an Implantable Blood Glucose Sensor for Diabetic Patients written by David A. Villarreal and published by . This book was released on 1996 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of a Robust Optical Glucose Sensor by : Gerard Laurence Coté
Download or read book Development of a Robust Optical Glucose Sensor written by Gerard Laurence Coté and published by . This book was released on 1990 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Minimally Invasive Glucometer Using the Magneto Optical Rotatory Effect (MORE) by : Sunghoon Jang
Download or read book Minimally Invasive Glucometer Using the Magneto Optical Rotatory Effect (MORE) written by Sunghoon Jang and published by . This book was released on 2002 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Glucose Sensing by : Chris D. Geddes
Download or read book Glucose Sensing written by Chris D. Geddes and published by Springer Science & Business Media. This book was released on 2007-12-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1978 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :IEEE Engineering in Medicine and Biology Society. Annual Conference Publisher : ISBN 13 : Total Pages :520 pages Book Rating :4.3/5 (91 download)
Book Synopsis Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society by : IEEE Engineering in Medicine and Biology Society. Annual Conference
Download or read book Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society written by IEEE Engineering in Medicine and Biology Society. Annual Conference and published by . This book was released on 1991 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biosensors for Medical Applications by : Séamus Higson
Download or read book Biosensors for Medical Applications written by Séamus Higson and published by Elsevier. This book was released on 2012-08-21 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical sensors are an essential tool in the detection and monitoring of a wide range of medical conditions from cancer to Parkinson's disease. Biosensors for medical applications provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications.Part one focuses on key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors. Impedence interrogated affinity biosensors for medical applications and practical applications of enzyme biosensors are explored, before part two goes on to review specific medical applications. Biosensors for DNA and RNA detection and characterization, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors are investigated, along with biosensors for drug testing and discovery, non-invasive measurements, and wearable biosensors for medical applications.With its distinguished editor and international team of expert contributors, Biosensors for medical applications is an essential guide for all those involved in the research, design, production and use of medical biosensors. - Provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications - Examines key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors - Reviews biosensors for DNA and RNA detection and characterisation, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors
Book Synopsis Photoplethysmography by : Panicos A. Kyriacou
Download or read book Photoplethysmography written by Panicos A. Kyriacou and published by Academic Press. This book was released on 2021-11-03 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photoplethysmography: Technology, Signal Analysis, and Applications is the first comprehensive volume on the theory, principles, and technology (sensors and electronics) of photoplethysmography (PPG). It provides a detailed description of the current state-of-the-art technologies/optical components enabling the extreme miniaturization of such sensors, as well as comprehensive coverage of PPG signal analysis techniques including machine learning and artificial intelligence. The book also outlines the huge range of PPG applications in healthcare, with a strong focus on the contribution of PPG in wearable sensors and PPG for cardiovascular assessment. - Presents the underlying principles and technology surrounding PPG - Includes applications for healthcare and wellbeing - Focuses on PPG in wearable sensors and devices - Presents advanced signal analysis techniques - Includes cutting-edge research, applications and future directions
Book Synopsis Annual Northeast Bioengineering Conference by :
Download or read book Annual Northeast Bioengineering Conference written by and published by . This book was released on 1990 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
