A Practical Approach to Toxicological Investigations

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521341189
Total Pages : 216 pages
Book Rating : 4.3/5 (411 download)

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Book Synopsis A Practical Approach to Toxicological Investigations by : Alan Poole

Download or read book A Practical Approach to Toxicological Investigations written by Alan Poole and published by Cambridge University Press. This book was released on 1989-12-14 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1989, this book acknowledges that new drugs, food additives and other compounds need to be carefully screened for toxic side-effects. The bulk of this study is devoted to the practical questions of 'what toxicological studies should we perform?' and 'how should we perform them?' Compounds which undergo toxicity testing may be conveniently categorised as those which are intended for administration to man and those which are not. The former include pharmaceuticals to be used medicinally or prophylactically and chemicals which are added to our food, drinks or medicine to improve their stability, appearance or palatability. Since it is on pharmaceuticals that the most comprehensive toxicological evaluations are generally performed, this book has been directed primarily towards to toxicological evaluation of potential new drugs. The principles and methodology of toxicological evaluation of other types of compounds are essentially similar.

A Guide to Practical Toxicology

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Author :
Publisher :
ISBN 13 : 9780203270042
Total Pages : 319 pages
Book Rating : 4.2/5 (7 download)

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Book Synopsis A Guide to Practical Toxicology by :

Download or read book A Guide to Practical Toxicology written by and published by . This book was released on 2003 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology is a means to an important end: safety. The effective toxicologist begins with this in mind, and uses a clear understanding of safety as a relative concept, together with a rational view of the current safety evaluation paradigm to direct their work. Too often this approach is ignored or discouraged by traditional practice. This lucid, readable book encourages both experienced toxicologists and those in training to place toxicological investigation in such a framework.

Handbook of Forensic Toxicology for Medical Examiners

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Author :
Publisher : CRC Press
ISBN 13 : 1351260588
Total Pages : 180 pages
Book Rating : 4.3/5 (512 download)

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Book Synopsis Handbook of Forensic Toxicology for Medical Examiners by : D. K. Molina, M.D.

Download or read book Handbook of Forensic Toxicology for Medical Examiners written by D. K. Molina, M.D. and published by CRC Press. This book was released on 2018-10-03 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic professionals, particularly medical examiners—often working through heavy caseloads—require quick and easy access to reliable sources of information to help interpret toxicology results. While several in-depth resources are available, they are often large, cumbersome, and contain more information than is often needed. The Handbook of Forensic Toxicology for Medical Examiners is a concise handbook referencing the most common toxic substances and their reported non-toxic, toxic, and lethal concentrations, making it an ideal text for quick reference in the lab or autopsy room. Features of the Second Edition: Explains the principles of postmortem toxicology and the factors which must be considered Provides tables of toxicologic data for over 200 commonly encountered substances, including drugs of abuse, poisons, prescription drugs, and over-the-counter medications Includes discussion and description of the novel psychoactive drugs—including synthetic opioids, cannabinoids, stimulants and hallucinogens Supplemental appendices provide additional information regarding specimen types and selection, testing methodologies, normal laboratory values, and conversion charts The busy forensic professional needs a concise handbook that provides critical information quickly and accurately. This heavily referenced text offers an easy-to-use format allowing for rapid access for both routine daily use and preparation for courtroom testimony.

Principles of Forensic Toxicology

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Author :
Publisher : Amer. Assoc. for Clinical Chemistry
ISBN 13 : 9781890883874
Total Pages : 406 pages
Book Rating : 4.8/5 (838 download)

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Book Synopsis Principles of Forensic Toxicology by : Barry Levine

Download or read book Principles of Forensic Toxicology written by Barry Levine and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2003 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Practical Guide to Toxicology and Human Health Risk Assessment

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Author :
Publisher :
ISBN 13 : 9781118881880
Total Pages : pages
Book Rating : 4.8/5 (818 download)

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Book Synopsis A Practical Guide to Toxicology and Human Health Risk Assessment by : Laura Robinson

Download or read book A Practical Guide to Toxicology and Human Health Risk Assessment written by Laura Robinson and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides a practical and easy-to-use guide to the applications of toxicology for risk assessment - Focuses on toxicological risk assessment of chemical and environmental compounds and includes real-life examples like pesticides, alcohol, and cigarettes and their impact on human health - Addresses the similarities and differences between USA and EU regulatory requirements Contains self-test questions and a summary of the key points in each chapter. Toxicologists, industrial hygienists, regulatory professionals, chemical risk assessors, forensic scientists, chemists, health and safety professionals, product safety workers; Medical and occupational health personnel who need to interpret toxicology data; Students studying toxicology or dealing with the topic in related disciplines, like forensic science, health, and medicine"--

Practical Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1498709303
Total Pages : 528 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Practical Toxicology by : David Woolley

Download or read book Practical Toxicology written by David Woolley and published by CRC Press. This book was released on 2017-03-16 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data. Revised and updated chapters on risk assessment guide the reader to setting the foundations necessary for submission to regulatory authorities. In addition, a new chapter in the book reviews the errors in toxicology, mistakes, misuse, mismanagement, and misunderstanding with a view to avoiding these in the future. New Chapters in the Third Edition: Toxicology in silico Errors in Toxicology Safety Assessment of Extractables and Leachables. This new edition follows a practical sequence from introducing the basics of toxicology (including the vital concept of normality in controls) to describing a test program and then interpreting the data and translating that to risk assessment that can be used in a number of real world situations where safety and secure risk assessment are essential. Although written primarily from the perspective of pharmaceutical development, the test designs and toxicological problems encountered in that field are entirely relevant to those with other classes of chemicals, the only difference being the regulatory context. Toxicology is an international discipline and the book has been written to take into account some of the differences in regulatory nuance between the main regions of the world. Completely revised and written in an easily accessible style, the text address several audiences—from students and post-graduates coming to the subject for the first time to established professionals who find themselves needing to learn about toxicology, toxicity testing, interpretation of the results, and risk assessment. It is intended primarily as a textbook, with case studies and information on where to go to ask questions, but can also be used as a practical reference book. It covers all the basics of toxicology and the main aspects of safety evaluation testing and risk assessment while reviewing critically the current state of the discipline. It also provides a foundation for those seeking registration or certification.

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

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Author :
Publisher : National Academies Press
ISBN 13 : 0309112982
Total Pages : 300 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment by : National Research Council

Download or read book Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2007-12-19 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.

Reference Manual on Scientific Evidence

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Author :
Publisher :
ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Reference Manual on Scientific Evidence by :

Download or read book Reference Manual on Scientific Evidence written by and published by . This book was released on 1994 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Practical Guide to Toxicology and Human Health Risk Assessment

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118882075
Total Pages : 402 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis A Practical Guide to Toxicology and Human Health Risk Assessment by : Laura Robinson

Download or read book A Practical Guide to Toxicology and Human Health Risk Assessment written by Laura Robinson and published by John Wiley & Sons. This book was released on 2018-11-05 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.

Toxicity Testing in the 21st Century

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Author :
Publisher : National Academies Press
ISBN 13 : 0309109922
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing in the 21st Century by : National Research Council

Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-10-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.

Manual for investigating suspected outbreaks of illnesses of possible chemical etiology

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Author :
Publisher : World Health Organization
ISBN 13 : 9240021752
Total Pages : 120 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Manual for investigating suspected outbreaks of illnesses of possible chemical etiology by :

Download or read book Manual for investigating suspected outbreaks of illnesses of possible chemical etiology written by and published by World Health Organization. This book was released on 2021-07-14 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicological Survey of African Medicinal Plants

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Author :
Publisher : Elsevier
ISBN 13 : 0128004754
Total Pages : 742 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Toxicological Survey of African Medicinal Plants by : Victor Kuete

Download or read book Toxicological Survey of African Medicinal Plants written by Victor Kuete and published by Elsevier. This book was released on 2014-05-30 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. Offers a critical review of the methods used in toxicological survey of medicinal plants Provides up-to-date toxicological data on African medicinal plants and families Serves as a resource tool for students and scientists in the various areas of toxicology

Supplementary Mutagenicity Tests

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Publisher : Cambridge University Press
ISBN 13 : 052145073X
Total Pages : 179 pages
Book Rating : 4.5/5 (214 download)

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Book Synopsis Supplementary Mutagenicity Tests by : United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing

Download or read book Supplementary Mutagenicity Tests written by United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing and published by Cambridge University Press. This book was released on 1993-11-11 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.

Environmental Health and Toxicology

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Author :
Publisher :
ISBN 13 :
Total Pages : 122 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Environmental Health and Toxicology by : Kathryn S. Deck

Download or read book Environmental Health and Toxicology written by Kathryn S. Deck and published by . This book was released on 1991 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Toxicology

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Publisher : Elsevier
ISBN 13 : 0080548008
Total Pages : 9894 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Encyclopedia of Toxicology by : Bruce Anderson

Download or read book Encyclopedia of Toxicology written by Bruce Anderson and published by Elsevier. This book was released on 2005-05-31 with total page 9894 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of the Encyclopedia of Toxicology continues its comprehensive survey of toxicology. This new edition continues to present entries devoted to key concepts and specific chemicals. There has been an increase in entries devoted to international organizations and well-known toxic-related incidents such as Love Canal and Chernobyl. Along with the traditional scientifically based entries, new articles focus on the societal implications of toxicological knowledge including environmental crimes, chemical and biological warfare in ancient times, and a history of the U.S. environmental movement. With more than 1150 entries, this second edition has been expanded in length, breadth and depth, and provides an extensive overview of the many facets of toxicology. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. *Second edition has been expanded to 4 volumes *Encyclopedic A-Z arrangement of chemicals and all core areas of the science of toxicology *Covers related areas such as organizations, toxic accidents, historical and social issues, and laws *New topics covered include computational toxicology, cancer potency factors, chemical accidents, non-lethal chemical weapons, drugs of abuse, and consumer products and many more!

Basic Mutagenicity Tests

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521393478
Total Pages : 164 pages
Book Rating : 4.3/5 (934 download)

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Book Synopsis Basic Mutagenicity Tests by : David J. Kirkland

Download or read book Basic Mutagenicity Tests written by David J. Kirkland and published by Cambridge University Press. This book was released on 1990-08-31 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: A summary of the essential texts that must be performed on all new compounds before they can be registered for use in the UK.

Toxicological Aspects of Drug-Facilitated Crimes

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Author :
Publisher : Elsevier
ISBN 13 : 0124169694
Total Pages : 307 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Toxicological Aspects of Drug-Facilitated Crimes by : Pascal Kintz

Download or read book Toxicological Aspects of Drug-Facilitated Crimes written by Pascal Kintz and published by Elsevier. This book was released on 2014-03-22 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology. Brings together the latest research on the toxicological analysis of drug-facilitated crimes (DFC), with real-life case studies Provides up-to-date analytical techniques for determining toxicity levels in blood, urine, and hair Covers all types of toxicants involved in DFC, including alcohol, cannabis, MDMA, and a wide variety of pharmaceuticals