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Author : John Wood
Publisher : BookLife Accessible Readers
ISBN 13 : 9781801551540
Total Pages : 0 pages
Book Rating : 4.5/5 (515 download)
Download or read book A Parp in the Dark written by John Wood and published by BookLife Accessible Readers. This book was released on 2022-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An awful smell ruins the clowns' road trip. One of them is guilty - but who?
Author : Alexander Bürkle
Publisher : Springer Science & Business Media
ISBN 13 : 0387360050
Total Pages : 260 pages
Book Rating : 4.3/5 (873 download)
Download or read book Poly(ADP-Ribosyl)ation written by Alexander Bürkle and published by Springer Science & Business Media. This book was released on 2008-01-11 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive, up-to-date reference on this post-translational modification of proteins, which is intimately linked with DNA repair, maintenance of genomic stability, transcriptional regulation, cell death and a variety of other cellular phenomena as well as with a variety of pathophysiological conditions, including ischemia-reperfusion damage, Parkinson’s disease, Type I diabetes mellitus, hemorrhagic and septic shock and other inflammatory conditions. Richly illustrated, it offers 19 chapters written by international experts.
Author : David A. Frank
Publisher : Springer Science & Business Media
ISBN 13 : 1402073402
Total Pages : 358 pages
Book Rating : 4.4/5 (2 download)
Download or read book Signal Transduction in Cancer written by David A. Frank and published by Springer Science & Business Media. This book was released on 2002-12-31 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Author : Derek Landy
Publisher : HarperCollins Children's Books
ISBN 13 : 9780008242794
Total Pages : 32 pages
Book Rating : 4.2/5 (427 download)
Download or read book Old MacDonald Heard a Fart written by Derek Landy and published by HarperCollins Children's Books. This book was released on 2017-04-06 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Old Macdonald heard a fart ... E-I-E-I-O!" There are some VERY rude noises coming from Old Macdonald's farm - who could be responsible?! Sing along to this side-splitting picture book adaptation of everyone's favourite nursery rhyme.
Author : Mark D. Evans
Publisher : Springer Science & Business Media
ISBN 13 : 0387729747
Total Pages : 228 pages
Book Rating : 4.3/5 (877 download)
Download or read book Oxidative Damage to Nucleic Acids written by Mark D. Evans and published by Springer Science & Business Media. This book was released on 2009-06-11 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides up-to-date coverage of selected topics in nucleic acid oxidation. The topics have been selected to cover everything from basic chemical mechanisms, repair of damage and the biological and pathological meaning of DNA oxidation. The chapters are authored by leading, research active, international experts in the respective topics.
Author : G.J.L. Kaspers
Publisher : Springer Science & Business Media
ISBN 13 : 9780306460555
Total Pages : 664 pages
Book Rating : 4.4/5 (65 download)
Download or read book Drug Resistance in Leukemia and Lymphoma III written by G.J.L. Kaspers and published by Springer Science & Business Media. This book was released on 1999-09-30 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular drug resistance is a major limitation to the success of chemotherapy of leu kemia and lymphoma. The importance of this has now been recognized by both clinicians and scientists. It is of utmost importance to bridge the gap between laboratory and clinic in this field of research. This is the main purpose of the series of International Symposia on Drug Resistance in Leukemia and Lymphoma. These are held every three years in Am sterdam, The Netherlands, since 1992. This book contains the proceedings of the third of these meetings, organised in 1998. The book covers all important aspects of drug resistance in leukemia and lymphoma, both in the form of extensive reviews as in manuscripts describing original data. General mechanisms of resistance are discussed, including the drug resistance related proteins p glycoprotein, MRP (multi-drug resistance protein) and LRP (lung resistance protein), and the role of glutathione and glutathione-S-transferases. Moreover, more drug type-specific mechanisms of resistance are a topic, such as for glucocorticoids and antifolates. Much in formation is provided on apoptosis and its regulators, and on the results of cell culture drug resistance assays. Several papers focus on the modulation or circumvention of drug resistance.
Author : ARTHUR KOESTELERS
Publisher :
ISBN 13 :
Total Pages : 226 pages
Book Rating : 4./5 ( download)
Download or read book DARKNESS AT NOON written by ARTHUR KOESTELERS and published by . This book was released on 1941 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert N. Trigiano
Publisher : CRC Press
ISBN 13 : 1482226936
Total Pages : 578 pages
Book Rating : 4.4/5 (822 download)
Download or read book Plant Pathology Concepts and Laboratory Exercises written by Robert N. Trigiano and published by CRC Press. This book was released on 2007-11-30 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised and updated with new concepts, case studies, and laboratory exercises, Plant Pathology Concepts and Laboratory Exercises, Second Edition supplies highly detailed and accurate information in a well-organized and accessible format. New additions to the second edition include five new topic and exercise chapters on soilborne pathogens, molecular tools, biocontrol, and plant-fungal interactions, information on in vitro pathology, an appendix on plant pathology careers, and how to use and care for the microscope. An accompanying cd-rom contains figures from the text as well as supplemental full-color photos and PowerPoint slides. Unique Learning Tools Retaining the informal style of the previous edition, this volume begins each topic with a concept box to highlight important ideas. Several laboratory exercises support each topic and cater to a wide range of skill sets from basic to complex. Procedure boxes for the experimental exercises give detailed outlines and comments on the experiments, step by step instruction, anticipated results, and thought provoking questions. Case studies of specific diseases and processes are presented as a bulleted list supplying essential information at a glance. Comprehensive Coverage Divided into six primary parts, this valuable reference introduces basic concepts of plant pathology with historical perspectives, fundamental ideas of disease, and disease relationships with the environment. It details various disease-causing organisms including viruses, prokaryotic organisms, plant parasitic nematodes, fungi, plant parasitic seed plants, and other biotic and abiotic diseases. Exploring various plant-pathogen interactions including treatments of molecular attack strategies, extracellular enzymes, host defenses, and disruption of plant function, the book presents the basic ideas of epidemiology, control strategies, and disease diagnosis.
Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author : Sarah Waters
Publisher : Bloomsbury Publishing
ISBN 13 : 1350014087
Total Pages : 138 pages
Book Rating : 4.3/5 (5 download)
Download or read book The Night Watch written by Sarah Waters and published by Bloomsbury Publishing. This book was released on 2016-07-28 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: I thought everything would change, after the war. And now, no one even mentions it. It is as if we all got together in private and said whatever you do don't mention that, like it never happened. It's the late 1940s. Calm has returned to London and five people are recovering from the chaos of war. In scenes set in a quiet dating agency, a bombed-out church and a prison cell, the stories of these five lives begin to intertwine and we uncover the desire and regret that has bound them together. Sarah Waters's story of illicit love and everyday heroism takes us from a dazed and shattered post-war Britain back into the heart of the Blitz, towards the secrets that are hidden there. Olivier-nominated playwright Hattie Naylor has created a thrilling and theatrically inventive adaptation of a great modern novel. The stage adaptation of The Night Watch was premiered at the Royal Exchange Theatre, Manchester, on 16 May 2016.
Author : Gerald P. Schatten
Publisher : Elsevier
ISBN 13 : 0080490905
Total Pages : 213 pages
Book Rating : 4.0/5 (84 download)
Download or read book Current Topics in Developmental Biology written by Gerald P. Schatten and published by Elsevier. This book was released on 2003-11-07 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together with other volumes in this series, Volume 56 of Current Topics in Developmental Biology presents thoughtful and forward-looking articles on developmental biology and developmental medicine. Reviews include: Selfishness in moderation: evolutionary success of the yeast plasmid Nongenomic actions of androgen in sertoli cells Regulation of chromatin structure and gene activity by Poly(ADP-ribose) polymerases Centromeres and Kinetochores, Who Needs 'Em? The Role of Non-centromeric Chromatin in Spindle Assembly Modeling Cardiogenesis: The Challenges and Promises of 3D Reconstruction Plasmid and Chromosome Traffic Control: How ParA and ParB Drive Partition The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development. Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
Author : Laura Bates
Publisher : Simon and Schuster
ISBN 13 : 150116919X
Total Pages : 336 pages
Book Rating : 4.5/5 (11 download)
Download or read book Girl Up written by Laura Bates and published by Simon and Schuster. This book was released on 2017-07-11 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: "They" told you that you need to be thin and beautiful; warned you that if you try to be strong, or take control, you'll be shrill, bossy, a ballbreaker. Well, screw that. Bates is here to expose the truth about the pressures surrounding body image, the trials of social media, and all the other lies society has told us. The result is no-nonsense advice on sex, social media, mental health, and sexism that young women face in their everyday life.
Author : Csaba Szabo
Publisher : CRC Press
ISBN 13 : 1420038893
Total Pages : 354 pages
Book Rating : 4.4/5 (2 download)
Download or read book Cell Death written by Csaba Szabo and published by CRC Press. This book was released on 2000-06-22 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poly (ADP-ribose) polymerase (PARP), also termed poly (ADP-ribose) synthetase (PARS) is a nuclear enzyme with a wide range of functions, including regulation of DNA repair, cell differentiation, and gene expression. More than a decade after the identification of PARP-like enzymatic activities in mammalian cells, a novel role was proposed for this e
Author : Renato Paro
Publisher : Springer Nature
ISBN 13 : 3030686701
Total Pages : 215 pages
Book Rating : 4.0/5 (36 download)
Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Author : Peter Bently
Publisher : Simon and Schuster
ISBN 13 : 1471164136
Total Pages : 32 pages
Book Rating : 4.4/5 (711 download)
Download or read book Princesses Don't Parp written by Peter Bently and published by Simon and Schuster. This book was released on 2019-08-08 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Princess is getting ready for her ball at the palace of Par Ping. She's starting to feel nervous. What happens if she pumps or parps or does bum-blasts or toots, bottom-burps, whizpops or poots? That shouldn't be a problem though, as everyone knows princesses don't pump... A new laugh-out-loud new text from Peter Bently, author of Meet the Parents and Dustbin Dad.
Author :
Publisher : Prentice Hall
ISBN 13 : 9780835911788
Total Pages : 0 pages
Book Rating : 4.9/5 (117 download)
Download or read book Globe Life Science written by and published by Prentice Hall. This book was released on 1998-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jerry L. Workman
Publisher : Springer Science & Business Media
ISBN 13 : 1461486246
Total Pages : 594 pages
Book Rating : 4.4/5 (614 download)
Download or read book Fundamentals of Chromatin written by Jerry L. Workman and published by Springer Science & Business Media. This book was released on 2013-12-04 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.
