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Author : Beverley Rebecca Vaughan
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)
Download or read book A molecular cytogenetic profile of the chronic myeloproliferative disorders written by Beverley Rebecca Vaughan and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Barbara J. Bain
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805573073
Total Pages : 137 pages
Book Rating : 4.8/5 (55 download)
Download or read book Chronic Myeloproliferative Disorders written by Barbara J. Bain and published by Karger Medical and Scientific Publishers. This book was released on 2003 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides a comprehensive and up-to-date review of the significance of cytogenetic and molecular genetic abnormalities in the chronic myeloid leukaemias and other myeloproliferative disorders. This book will therefore be an important reference text, not only for haematologists, but also for molecular geneticists and cytogeneticists, and anyone involved in leukaemia research.
Author : H.L. Pahl
Publisher : Springer Science & Business Media
ISBN 13 : 3642187382
Total Pages : 242 pages
Book Rating : 4.6/5 (421 download)
Download or read book Molecular Basis of Chronic Myeloproliferative Disorders written by H.L. Pahl and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first description of Philadelphia chromosome-negative chronic myeloproliferative disorders more than 100 years ago, the diagnosis and therapy of these conditions have been based primarily on clinical experience and judgement. Until recently very little was known about the molecular basis of these diseases. In order to spark research in this area basic scientists and clinicians from various parts of the world have contributed to this volume, the first of its kind to put together the current knowledge. The book deals with the new WHO classification of these disorders, novel aspects of diagnostic pathology, the search for disease-relevant genes utilizing molecular biology and proteomic techniques, the description of the roles of PVR-1 and VHL genes for polycythemias and the discovery of the gene mutation responsible for the idiopathic hypereosinophilic syndrome. A chapter on anagrelide, an important novel drug for the treatment of primary thrombocythemia, is included.
Author : B.J. Bain
Publisher :
ISBN 13 : 9783318007725
Total Pages : 0 pages
Book Rating : 4.0/5 (77 download)
Download or read book Chronic Myeloproliferative Disorders written by B.J. Bain and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides a comprehensive and up-to-date review of the significance of cytogenetic and molecular genetic abnormalities in the chronic myeloid leukaemias and other myeloproliferative disorders. Subjects discussed include polycythaemia vera, essential thrombocythaemia, 'idiopathic' myelofibrosis and BCR-ABL-positive chronic myeloid leukaemia. The role of cytogenetic and molecular genetic analysis in monitoring residual disease in chronic myeloid leukaemia is also comprehensively covered. In addition, the less common entities of the 8p11 syndrome, systemic mastocytosis, eosinophilic leukaemia and chronic myeloid leukaemia associated with t(5;12) are reviewed in detail. With the development of drugs with a specific molecular target, molecular aspects of chronic leukaemias will become increasingly relevant to the practice of haematology, making this publication very timely. The contributing authors include leaders in the fields of haematology and cytogenetics who have carefully reviewed and updated published data and drawn on their own considerable experience. This book will therefore be an important reference text, not only for haematologists, but also for molecular geneticists and cytogeneticists, and anyone involved in leukaemia research.
Author : Barbara J. Bain
Publisher :
ISBN 13 : 9783805574099
Total Pages : 0 pages
Book Rating : 4.5/5 (74 download)
Download or read book Cytogenetic and Molecular Genetic Aspects of Myeloproliferative Disorders written by Barbara J. Bain and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides a comprehensive and up-to-date review of the significance of cytogenetic and molecular genetic abnormalities in the chronic myeloid leukaemias and systemic mastocytosis. Subjects discussed include BCR-ABL-positive chronic myeloid leukaemia, the 8p11 syndrome, and chronic myelomonocytic and other leukaemias associated with t(5;12). The role of cytogenetic and molecular genetic analysis in monitoring residual disease in chronic myeloid leukaemia is also comprehensively covered. With the development of drugs with a specific molecular target, molecular aspects of chronic leukaemias will become increasingly relevant to the practice of haematology, making this special issue very timely. The contributing authors include leaders in the fields of haematology and cytogenetics who have carefully reviewed and updated published data and drawn on their own considerable experience. Therefore, this issue will be an important reference not only for haematologists, but also for molecular geneticists and cytogeneticists, and anyone involved in leukaemia research.
Author : J.V. Melo
Publisher : Springer Science & Business Media
ISBN 13 : 354034506X
Total Pages : 356 pages
Book Rating : 4.5/5 (43 download)
Download or read book Myeloproliferative Disorders written by J.V. Melo and published by Springer Science & Business Media. This book was released on 2007-03-06 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a series of contributions from internationally renowned academics with special expertise in one or other diseases which collectively are grouped under the heading myeloproliferative disorders. There have been many recent developments in understanding the pathophysiology and a number therapeutic innovations in this area. A feature of this book is the speed with which it has been produced – an important factor in this rapidly moving field.
Author : Chung-Che (Jeff) Chang
Publisher : Springer
ISBN 13 : 3319621467
Total Pages : 428 pages
Book Rating : 4.3/5 (196 download)
Download or read book Precision Molecular Pathology of Myeloid Neoplasms written by Chung-Che (Jeff) Chang and published by Springer. This book was released on 2017-09-25 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive, state-of-the art review of myeloid neoplasms. The book presents updated information on epidemiology, clinical presentation, morphologic findings, molecular genomic abnormalities, pathogenesis, and target therapies. The text helps to guide accurate diagnosis, the administration of appropriate ancillary molecular tests, patient management, and investigative efforts. The book also includes over 200 illustrations, photographs, and tables. Written by experts in the field, Precision Molecular Pathology of Myeloid Neoplasms serves as a valuable resource for pathologists, hematologists/oncologists, fellows, and researchers in understanding the molecular pathology of myeloid neoplasms.
Author : Richard T. Silver
Publisher : CRC Press
ISBN 13 : 1420061631
Total Pages : 239 pages
Book Rating : 4.4/5 (2 download)
Download or read book Myeloproliferative Disorders written by Richard T. Silver and published by CRC Press. This book was released on 2007-10-11 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the recent discovery of JAK2 mutations in myeloproliferative disorders, medical science has taken a revolutionary stride forward toward understanding the pathogenesis of these diseases. This new advancement translates not only to a more rapid and reliable diagnosis, but also allows groundbreaking research into the development of new therapeuti
Author : Sverre Heim
Publisher : John Wiley & Sons
ISBN 13 : 1118210581
Total Pages : 799 pages
Book Rating : 4.1/5 (182 download)
Download or read book Cancer Cytogenetics written by Sverre Heim and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 799 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Cytogenetics, 3rd Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area and incorporates a vast amount of new data from the latest basic and clinical investigations. Edited by two leading experts, and now involving a new panel of international experts, the book offers an authoritative description of neoplastic processes at the chromosomal level of genomic organization. Researchers in cytogenetics, medical and molecular genetics, cellular and molecular biology, cancer research, clinical oncology, and hematology will find this reference both thorough and authoritative.
Author : Tariq Mughal
Publisher : CRC Press
ISBN 13 : 9780415415989
Total Pages : 0 pages
Book Rating : 4.4/5 (159 download)
Download or read book Chronic Myeloproliferative Disorders written by Tariq Mughal and published by CRC Press. This book was released on 2008-08-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the new classification of chronic myeloproliferative disorders, and the rise of interest in molecularly targeted therapies, this timely text brings together international experts on the topic to discuss the current technologies and their implications for the treatment of patients. This title comprehensively covers chronic myeloid leukemia and Ph-negative chronic myeloproliferative disorders and is an essential resource for all practitioners in Hematologic Oncology.
Author : Hillard M. Lazarus
Publisher : Springer Science & Business Media
ISBN 13 : 1597454788
Total Pages : 885 pages
Book Rating : 4.5/5 (974 download)
Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Author : Tiziano Barbui
Publisher : Springer Science & Business Media
ISBN 13 : 3642249884
Total Pages : 235 pages
Book Rating : 4.6/5 (422 download)
Download or read book Myeloproliferative Neoplasms written by Tiziano Barbui and published by Springer Science & Business Media. This book was released on 2012-02-03 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.
Author : Debra G.B. Leonard
Publisher : Springer Science & Business Media
ISBN 13 : 0387332278
Total Pages : 589 pages
Book Rating : 4.3/5 (873 download)
Download or read book Molecular Pathology in Clinical Practice written by Debra G.B. Leonard and published by Springer Science & Business Media. This book was released on 2007-11-25 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. The text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. Discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more. Includes 189 illustrations, 45 in full-color. This textbook is a classic in the making and a must-have reference.
Author : Faramarz Naeim
Publisher : Academic Press
ISBN 13 : 0080919480
Total Pages : 612 pages
Book Rating : 4.0/5 (89 download)
Download or read book Hematopathology written by Faramarz Naeim and published by Academic Press. This book was released on 2009-03-05 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review of immunophenotypic, cytogenetic and molecular findings. The text is balanced with large numbers of full color images, graphs, charts, and tables to assist the reader in understanding these highly technical issues. Emphasizes the immunophenotypic features, cytogenetic studies, and diagnostic molecular aspects of hematology Features hundreds of images, charts and tables for the identification of hematologic disorders not only based on histopathologic features, but also with the use of advanced accessory techniques
Author : Anna Porwit
Publisher :
ISBN 13 : 9780702031472
Total Pages : 0 pages
Book Rating : 4.0/5 (314 download)
Download or read book Blood and Bone Marrow Pathology written by Anna Porwit and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Already a standard reference work in the field, the new edition of Blood and Bone Marrow Pathology incorporates the latest WHO classification schemes and the latest ancillary diagnostic techniques in immunohistochemistry and molecular biology in order to provide a comprehensive, well balanced and authoritative guide to the interpretation and diagnosis of neoplastic and non-neoplastic diseases of blood and bone marrow. The text is lavishly illustrated with high quality colour images that demonstrate the relevant pathological,features and immunohistochemical and molecular markers. The text features a well-organized approach that incorporates practical tips and clues to help avoid pitfalls and to ensure optimal diagnosis The book is lavishly illustrated with high quality color images that demonstrate the relevant pathological features and immunohistochemical and molecular markers. The text features a well-organized approach that incorporates practical tips and clues to help avoid pitfalls and to ensure optimal diagnosis. Chapters have been totally rewritten and new chapters have been added, especially on myeloid malignancies. The chapters on hematological malignancies have been written so that the reader can apply the latest WHO Classifications in their routine daily practice (especially the 2008 WHO Classification of Tumors of Hemopoietic and Lymphoid Tissues) All chapters have been revised to include new aspects of molecular biology and flow cytometry diagnostics. Many new schematic diagrams and color illustrations have been added to illustrate blood and bone marrow pathology. Access the full text online and download images via Expert Consult. Chapters have been totally rewritten and some new chapters have been added especially on myeloid malignancies, in line with the WHO 2008 Classification All chapters have been revised to include new aspects of molecular biology and updated concerning flow cytometry diagnostics Greater emphasis on practical diagnostic aspects for all disorders Brand new editorial and contributing author team. Full Online text through Expert Consult. Full downloadable Image Bank Already a standard reference work in the field, the new edition of Blood and Bone Marrow Pathology incorporates the latest WHO classification schemes and the latest ancillary diagnostic techniques in immunohistochemistry and molecular biology in order to provide a comprehensive, well balanced and authoritative guide to the interpretation and diagnosis of neoplastic and non-neoplastic diseases of blood and bone marrow. The text is lavishly illustrated with high quality colour images that demonstrate the relevant pathological,features and immunohistochemical and molecular markers. The text features a well-organized approach that incorporates practical tips and clues to help avoid pitfalls and to ensure optimal diagnosis
Author : Ruben A. Mesa
Publisher : Cambridge University Press
ISBN 13 : 1316033775
Total Pages : 207 pages
Book Rating : 4.3/5 (16 download)
Download or read book Managing Myeloproliferative Neoplasms written by Ruben A. Mesa and published by Cambridge University Press. This book was released on 2016-03-31 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise, practical, case-based book documenting examples and scenarios that will help you manage challenging clinical issues for patients with myeloproliferative neoplasms. The editors and authors have strived to distil the very latest information in this rapidly advancing field in a way that will help you to update your practice and manage your patients. The key focuses are: diagnosis, both standard and challenging; both day-to-day management as well as special situations such as surgery, thrombotic events and pregnancy; and finally, managing evolving situations with MPN such as progression to acute myeloid leukemia. This book is an outstanding resource that includes a discussion of both classical myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera and myelofibrosis, and also less common disorders such as systemic mast cell disease, hypereosinophilia, MPN/MBS overlap syndromes and atypical CML, amongst others. This book is a practical reference for practitioners, hematologists, medical oncologists and trainees.
Author : Pedro A. de Alarcón
Publisher : Cambridge University Press
ISBN 13 : 1108488986
Total Pages : 501 pages
Book Rating : 4.1/5 (84 download)
Download or read book Neonatal Hematology written by Pedro A. de Alarcón and published by Cambridge University Press. This book was released on 2021-02-18 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.
