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A Model Study
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Book Synopsis Animal Models for the Study of Human Disease by : P. Michael Conn
Download or read book Animal Models for the Study of Human Disease written by P. Michael Conn and published by Academic Press. This book was released on 2013-05-29 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. - Organized by disease orientation for ease of searchability - Provides information on locating resources, animal alternatives and animal ethics - Covers a broad range of animal models used in research for human disease
Book Synopsis A Model Study of Dynamically Loaded Square Footings on Dry Sand by : Jack K. Poplin
Download or read book A Model Study of Dynamically Loaded Square Footings on Dry Sand written by Jack K. Poplin and published by . This book was released on 1969 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: The investigation reported herein was undertaken to develop an approach to modeling displacements of surface and shallow-buried footings on dry sand subject to high-intensity, single-pulse loads. A hypothetical shallow-bured structure with an isolated footing loaded by airblast overpressure produced by detonation of a nuclear weapon was assumed for design of load pulses on nine model footings used: footing widths of 4.5, 6.0, and 7.5 in. and depth-of-burial to footing width ratios of 0, 0.5, and 1.0. The principles of similitude were used to scale length, force, and time in the models. The models were placed in mobile test bins of uniform, fine, dry sand (90 percent relative density) and subjected to dynamic and static loading. Nondimensional load-displacement relations dependent only on depth-of-burial ratio were developed relating maximum displacement to peak dynamic load, footing width, and soil shear strength gradient. When the dynamic response of the footings in the form of reaction-displacement curves was compared with static response, an increase in initial stiffness and ultimate strength was observed for dynamic loading. However, these dynamic increases were greatest when the static shear strength was lowest, i.e. footings on the surface, and were least for footings buried at a depth equal to its width where the static overburden produced a substantial increase in shear strength. (Author).
Book Synopsis A Model Study of the Entrance Channel, Depoe Bay, Oregon by : John P. Ahrens
Download or read book A Model Study of the Entrance Channel, Depoe Bay, Oregon written by John P. Ahrens and published by . This book was released on 1967 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Model Study of the Small Boy Footing Behavior by : Paul F. Hadala
Download or read book A Model Study of the Small Boy Footing Behavior written by Paul F. Hadala and published by . This book was released on 1967 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Concepts and Models for Drug Permeability Studies by : Bruno Sarmento
Download or read book Concepts and Models for Drug Permeability Studies written by Bruno Sarmento and published by Woodhead Publishing. This book was released on 2015-09-30 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route. - Updated information regarding the most recent in vitro models to study the permeability of drugs - Short and concise chapters covering all the biological barriers with interest in drug permeability - A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models - Simple and clear scientific content, adaptable for young scientists and experimented researchers
Book Synopsis A Model Study of Maintenance Works at Ballona Creek Outlet, Venice, California by : Waterways Experiment Station (U.S.)
Download or read book A Model Study of Maintenance Works at Ballona Creek Outlet, Venice, California written by Waterways Experiment Station (U.S.) and published by . This book was released on 1937 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis R for Data Science by : Hadley Wickham
Download or read book R for Data Science written by Hadley Wickham and published by "O'Reilly Media, Inc.". This book was released on 2016-12-12 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how to use R to turn raw data into insight, knowledge, and understanding. This book introduces you to R, RStudio, and the tidyverse, a collection of R packages designed to work together to make data science fast, fluent, and fun. Suitable for readers with no previous programming experience, R for Data Science is designed to get you doing data science as quickly as possible. Authors Hadley Wickham and Garrett Grolemund guide you through the steps of importing, wrangling, exploring, and modeling your data and communicating the results. You'll get a complete, big-picture understanding of the data science cycle, along with basic tools you need to manage the details. Each section of the book is paired with exercises to help you practice what you've learned along the way. You'll learn how to: Wrangle—transform your datasets into a form convenient for analysis Program—learn powerful R tools for solving data problems with greater clarity and ease Explore—examine your data, generate hypotheses, and quickly test them Model—provide a low-dimensional summary that captures true "signals" in your dataset Communicate—learn R Markdown for integrating prose, code, and results
Download or read book What Is a Book? written by JOSEPH A. DANE and published by . This book was released on 2022-01-15 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Joseph A. Dane's What Is a Book? is an introduction to the study of books produced during the period of the hand press, dating from around 1450 through 1800. Using his own bibliographic interests as a guide, Dane selects illustrative examples primarily from fifteenth-century books, books of particular interest to students of English literature, and books central to the development of Anglo-American bibliography. Part I of What Is a Book? covers the basic procedures of printing and the parts of the physical book--size, paper, type, illustration; Part II treats the history of book-copies--from cataloging conventions and provenance to electronic media and their implications for the study of books. Dane begins with the central distinction between a "book-copy"--the particular, individual, physical book--and a "book"--the abstract category that organizes these copies into editions, whereby each copy is interchangeable with any other. Among other issues, Dane addresses such basic questions as: How do students, bibliographers, and collectors discuss these things? And when is it legitimate to generalize on the basis of particular examples? Dane considers each issue in terms of a practical example or question a reader might confront: How do you identify books on the basis of typography? What is the status of paper evidence? How are the various elements on the page defined? What are the implications of the images available in an online database? And, significantly, how does a scholar's personal experience with books challenge or conform to the standard language of book history and bibliography? Dane's accessible and lively tour of the field is a useful guide for all students of book history, from the beginner to the specialist.
Book Synopsis Data and Evidence in Linguistics by : András Kertész
Download or read book Data and Evidence in Linguistics written by András Kertész and published by Cambridge University Press. This book was released on 2012-02-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The question of what types of data and evidence can be used is one of the most important topics in linguistics. This book is the first to comprehensively present the methodological problems associated with linguistic data and evidence. Its originality is twofold. First, the authors' approach accounts for a series of unexplained characteristics of linguistic theorising: the uncertainty and diversity of data, the role of evidence in the evaluation of hypotheses, the problem solving strategies as well as the emergence and resolution of inconsistencies. Second, the findings are obtained by the application of a new model of plausible argumentation which is also of relevance from a general argumentation theoretical point of view. All concepts and theses are systematically introduced and illustrated by a number of examples from different linguistic theories, and a detailed case-study section shows how the proposed model can be applied to specific linguistic problems.
Book Synopsis Clinical Prediction Models by : Ewout W. Steyerberg
Download or read book Clinical Prediction Models written by Ewout W. Steyerberg and published by Springer. This book was released on 2019-07-22 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this volume provides insight and practical illustrations on how modern statistical concepts and regression methods can be applied in medical prediction problems, including diagnostic and prognostic outcomes. Many advances have been made in statistical approaches towards outcome prediction, but a sensible strategy is needed for model development, validation, and updating, such that prediction models can better support medical practice. There is an increasing need for personalized evidence-based medicine that uses an individualized approach to medical decision-making. In this Big Data era, there is expanded access to large volumes of routinely collected data and an increased number of applications for prediction models, such as targeted early detection of disease and individualized approaches to diagnostic testing and treatment. Clinical Prediction Models presents a practical checklist that needs to be considered for development of a valid prediction model. Steps include preliminary considerations such as dealing with missing values; coding of predictors; selection of main effects and interactions for a multivariable model; estimation of model parameters with shrinkage methods and incorporation of external data; evaluation of performance and usefulness; internal validation; and presentation formatting. The text also addresses common issues that make prediction models suboptimal, such as small sample sizes, exaggerated claims, and poor generalizability. The text is primarily intended for clinical epidemiologists and biostatisticians. Including many case studies and publicly available R code and data sets, the book is also appropriate as a textbook for a graduate course on predictive modeling in diagnosis and prognosis. While practical in nature, the book also provides a philosophical perspective on data analysis in medicine that goes beyond predictive modeling. Updates to this new and expanded edition include: • A discussion of Big Data and its implications for the design of prediction models • Machine learning issues • More simulations with missing ‘y’ values • Extended discussion on between-cohort heterogeneity • Description of ShinyApp • Updated LASSO illustration • New case studies
Book Synopsis Thresholds of Translation by : Marie-Alice Belle
Download or read book Thresholds of Translation written by Marie-Alice Belle and published by Springer. This book was released on 2018-07-28 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume revisits Genette’s definition of the printed book’s liminal devices, or paratexts, as ‘thresholds of interpretation’ by focussing specifically on translations produced in Britain in the early age of print (1473-1660). At a time when translation played a major role in shaping English and Scottish literary culture, paratexts afforded translators and their printers a privileged space in which to advertise their activities, display their social and ideological affiliations, influence literary tastes, and fashion Britain’s representations of the cultural ‘other’. Written by an international team of scholars of translation and material culture, the ten essays in the volume examine the various material shapes, textual forms, and cultural uses of paratexts as markers (and makers) of cultural exchange in early modern Britain. The collection will be of interest to scholars of early modern translation, print, and literary culture, and, more broadly, to those studying the material and cultural aspects of text production and circulation in early modern Europe.
Book Synopsis Occupancy Estimation and Modeling by : Darryl I. MacKenzie
Download or read book Occupancy Estimation and Modeling written by Darryl I. MacKenzie and published by Elsevier. This book was released on 2017-11-17 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Occupancy Estimation and Modeling: Inferring Patterns and Dynamics of Species Occurrence, Second Edition, provides a synthesis of model-based approaches for analyzing presence-absence data, allowing for imperfect detection. Beginning from the relatively simple case of estimating the proportion of area or sampling units occupied at the time of surveying, the authors describe a wide variety of extensions that have been developed since the early 2000s. This provides an improved insight about species and community ecology, including, detection heterogeneity; correlated detections; spatial autocorrelation; multiple states or classes of occupancy; changes in occupancy over time; species co-occurrence; community-level modeling, and more. Occupancy Estimation and Modeling: Inferring Patterns and Dynamics of Species Occurrence, Second Edition has been greatly expanded and detail is provided regarding the estimation methods and examples of their application are given. Important study design recommendations are also covered to give a well rounded view of modeling. - Provides authoritative insights into the latest in occupancy modeling - Examines the latest methods in analyzing detection/no detection data surveys - Addresses critical issues of imperfect detectability and its effects on species occurrence estimation - Discusses important study design considerations such as defining sample units, sample size determination and optimal effort allocation
Book Synopsis Model Study of Hopper Dredge Dragheads by : John J. Franco
Download or read book Model Study of Hopper Dredge Dragheads written by John J. Franco and published by . This book was released on 1967 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Collaborative Information Behavior: User Engagement and Communication Sharing by : Foster, Jonathan
Download or read book Collaborative Information Behavior: User Engagement and Communication Sharing written by Foster, Jonathan and published by IGI Global. This book was released on 2010-06-30 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book coordinates and integrates current research and practices in the area of collaborative information behavior, providing information on empirical research findings, theoretical frameworks, and models relevant to understanding collaborative information behavior"--Provided by publisher.
Book Synopsis Hydraulic Research in the United States and Canada by : United States. National Bureau of Standards
Download or read book Hydraulic Research in the United States and Canada written by United States. National Bureau of Standards and published by . This book was released on 1972 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Public Works for Water and Power Development and Energy Research Appropriations for Fiscal Year 1977 by : United States. Congress. Senate. Committee on Appropriations
Download or read book Public Works for Water and Power Development and Energy Research Appropriations for Fiscal Year 1977 written by United States. Congress. Senate. Committee on Appropriations and published by . This book was released on 1976 with total page 1396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hearings, Reports and Prints of the House Committee on Public Works by : United States. Congress. House. Committee on Public Works
Download or read book Hearings, Reports and Prints of the House Committee on Public Works written by United States. Congress. House. Committee on Public Works and published by . This book was released on 1968 with total page 1376 pages. Available in PDF, EPUB and Kindle. Book excerpt:
