Mast Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 1592599672
Total Pages : 434 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Mast Cells by : Guha Krishnaswamy

Download or read book Mast Cells written by Guha Krishnaswamy and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cutting-edge collection of readily reproducible techniques for the isolation, culture, and study of activation and signaling in human mast cells. These methods take advantage of the latest advances in molecular biology, technology, and information science. They include methods for the identification of mast cells, the development of mast cells in vitro, the study of mast cell signaling and gene expression, and the measurement of mast cell expression of inflammatory mediators. Additional chapters cover methods for studying mast cell interactions with other cell types (endothelial cells, fibroblasts, and B cells), the roles of mast cells in host defense, and mast cell apoptosis.

Basophils and Mast Cells

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Publisher : Springer Nature
ISBN 13 : 1071606964
Total Pages : 379 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Basophils and Mast Cells by : Bernhard F. Gibbs

Download or read book Basophils and Mast Cells written by Bernhard F. Gibbs and published by Springer Nature. This book was released on 2020-08-06 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides updated and new chapters to build on and extend the strengths of the first edition. Chapters guide readers through basic biology of basophils, obtaining the cells by purification, culture of stem cells progenitors, peripheral CD34+ stem cell-derived mast cells, basophils from CD34+ progenitors, diagnostic applications, gene expression patterns in basophils, roles of basophils in different asthma phenotypes, knockout, and disease models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Basophils and Mast Cells: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.

Basophil and Mast Cell Degranulation and Recovery

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306437526
Total Pages : 436 pages
Book Rating : 4.4/5 (375 download)

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Book Synopsis Basophil and Mast Cell Degranulation and Recovery by : Ann M. Dvorak

Download or read book Basophil and Mast Cell Degranulation and Recovery written by Ann M. Dvorak and published by Springer Science & Business Media. This book was released on 1991-08-31 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basophils and mast cells are similar but unique secretory cells with a well-documented role in immediate-hypersensitivity reactions. The presence of these cells in various cell mediated hypersensitivity reactions, in tissues of multiple diseases, and as a component of the host reaction to injury and repair in numerous circumstances is well known. Release of stored and newly generated mediators of inflammation from basophils and mast cells contributes to the cascade of pathogenetic events in circumstances under which these release reactions occur. Despite insights acquired through studies of these pathologic events, the role of basophils and mast cells and their secretory products in health is not known. In this book, I review much of the structural information regarding basophils and mast cells of multiple species. Ultrastructural studies of rat mast cells historically precede and quantitatively exceed similar studies of basophils and mast cells of other species. Therefore, I first review these background studies as an entity. Then I discuss the contents of two prominent organelles-granules and lipid bodies-in basophils and mast cells of several species. The ultrastructural morphology of basophils and mast cells in three species is presented in detail to establish appropriate guidelines for their recognition and to provide general rules for analysis which are appropriate for the identification of these cells in other species as well.

Mast Cells and Tumours

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Publisher : Springer Science & Business Media
ISBN 13 : 9400714696
Total Pages : 147 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Mast Cells and Tumours by : Domenico Ribatti

Download or read book Mast Cells and Tumours written by Domenico Ribatti and published by Springer Science & Business Media. This book was released on 2011-06-21 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast cells are versatile, tissue-homing secretory cells, which were first described by Paul Ehrlich in 1878. Mast cells have long been implicated in the pathogenesis of allergic reactions and certain protective responses to parasites. Their functional role, however, has been discovered to be increasingly complex and multifarious. Mast cells have been implicated in various cell-mediated immune reactions, being found in tissues from multiple disease sites, and as a component of the host reaction to bacteria, parasite, and even virus infections. They have also been shown to participate to angiogenic and tissue repair processes after injury. The importance of a possible functional link between chronic inflammation and cancer has long been recognized. As most tumours contain inflammatory cell infiltrates, which often include plentiful mast cells, the question as to the possible contribution of mast cells to tumour development has progressively been emerged. In this book, the general biology of these cells, their development, anatomical distribution and phenotype as well as their secretory products will first be discussed. The biology of tumour cells, their structural and molecular characteristics, the specificity of the tumour microenvironment and the development of a vascular network in the tumour context will be analyzed. The involvement of mast cells in tumour biology and tumour fate will then be considered, with particular emphasis on the capacity of these cells to stimulate tumour growth by promoting angiogenesis and lymphangiogenesis. The last chapter suggest that mast cells may serve as a novel therapeutic target for cancer treatment.

McBride Mast Families

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Publisher : Lulu.com
ISBN 13 : 0987822756
Total Pages : 194 pages
Book Rating : 4.9/5 (878 download)

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Book Synopsis McBride Mast Families by : John Eacott

Download or read book McBride Mast Families written by John Eacott and published by Lulu.com. This book was released on 2017-08-19 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes the descendents of Thomas Clarke McBride and Mary Elizabeth Mast. It more importantly gives the history of their ancestors from the earliest colonial times until the mid 1800's with both original research and existing material. Anyone interested in McBride, Mast, Farthing, Baird, Smith, Wilson, Green, Eggers, Harmon families with connection to the Watauga County area of North Carolina will be interested in this book. With today's interest in DNA and family trees this book may provide answers to who we are, where we came from, and why.

Program Manual for MAST Programs

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Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Program Manual for MAST Programs by : United States. Department of Transportation

Download or read book Program Manual for MAST Programs written by United States. Department of Transportation and published by . This book was released on 1977 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Signal Transduction in Mast Cells and Basophils

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Publisher : Springer Science & Business Media
ISBN 13 : 1461221544
Total Pages : 438 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Signal Transduction in Mast Cells and Basophils by : Ehud Razin

Download or read book Signal Transduction in Mast Cells and Basophils written by Ehud Razin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focussing on the molecular mechanisms that govern mast cell and basophil cell biology and function, this book also provides a comprehensive summary of the field of signal transduction, giving insights into areas that have therapeutic potential. It gives detailed insights into mast cell and basophil growth and development, their activation by allergens, including details of receptor activation and downstream events, and the regulators of morphology and degranulation. The metabolic pathways involved in prostaglandin and leukotriene production are discussed as is the role of transcription factors in mast cell growth and cytokine production. Written by leaders in the field, this volume will provide readers with an up-to-date account of a topic whose rapid progress makes conventional information gathering difficult.

Program Manual for MAST Programs

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Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Program Manual for MAST Programs by :

Download or read book Program Manual for MAST Programs written by and published by . This book was released on 1977 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Deciphering new molecular mechanisms of mast cell activation

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Author :
Publisher : Frontiers E-books
ISBN 13 : 2889191869
Total Pages : 135 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Deciphering new molecular mechanisms of mast cell activation by : Ulrich Blank

Download or read book Deciphering new molecular mechanisms of mast cell activation written by Ulrich Blank and published by Frontiers E-books. This book was released on 2014-03-20 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast cells are tissue-localized cells that play an important role in immunity and inflammation. Following an offensive event they act as cellular sensors that via the activation of cell surface receptors launch a cellular response culminating in the release of a whole set of inflammatory mediators and products. This response is initially destined to restore tissue homeostasis, but in case of chronic injury or deregulation also promotes pathology. To further understand the action of mast cells in their environmental context it is necessary to decipher the molecular mechanisms of their activation as well as the ensuing cellular responses. This will allow identification of new strategies to promote their beneficial actions or, at the contrary, to interfere with their pathological consequences. While in the past many studies have focused on responses engaged by high affinity IgE receptor because of its implication in the allergic response, it has become clear that mast cells can be activated by multiple types of receptors initiating an intense molecular crosstalk between receptors and signaling pathways that can either synergize, antagonize and in some cases produce new types of responses. Mast cells can indeed react with an astounding diverse array of cellular responses that sometimes are engaged selectively. This Research Topic will focus on selected articles that shed some new light on the molecular mechanisms of mast cell activation, the possible crosstalk between signaling pathways and the ensuing cellular responses that allow mast cells to act as cellular sensors in tissues.

The Trifecta Passport: Tools for Mast Cell Activation Syndrome, Postural Orthostatic Tachycardia Syndrome and Ehlers-Danlos Syndrome

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Author :
Publisher : Amber Walker
ISBN 13 : 1733711732
Total Pages : 503 pages
Book Rating : 4.7/5 (337 download)

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Book Synopsis The Trifecta Passport: Tools for Mast Cell Activation Syndrome, Postural Orthostatic Tachycardia Syndrome and Ehlers-Danlos Syndrome by : Amber Walker

Download or read book The Trifecta Passport: Tools for Mast Cell Activation Syndrome, Postural Orthostatic Tachycardia Syndrome and Ehlers-Danlos Syndrome written by Amber Walker and published by Amber Walker. This book was released on 2021-01-27 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The “trifecta” refers to three conditions that commonly occur together: mast cell activation syndrome (MCAS), postural orthostatic tachycardia syndrome (POTS) and the hypermobile type of Ehlers-Danlos syndrome (hEDS). These three conditions are gradually becoming more recognized in the mainstream medical world as more and more patients find themselves struggling with debilitating and often mysterious symptoms. However, recognizing these conditions is only the first step on the healing journey. With the right approach and toolbox, patients can reverse many of these symptoms to find lasting vitality. Written by a Doctor of Physical Therapy who has additional certifications in functional medicine and nutrition and extensive experience in working with these conditions, this book serves as patient guide that empowers individuals to put all of the puzzle pieces together as part of an individualized healing plan. Part One (3 chapters) is an overview of the three trifecta conditions, and Part Two (9 chapters) outlines the important pillars of an essential plan to address any (or all) of these conditions holistically. The book wraps up with a chapter of patient case stories. Accompanying the purchase of this book is access to a free 20-page PDF document that serves as a customizable workbook for readers to use as they read along. The Trifecta Passport dives into topics such as nervous system regulation, mold and other biotoxins, nutrition, exercise, detoxification, mental/emotional health and trauma, structural/musculoskeletal issues and the many underlying root issues (related to hormones, bacterial/viral load, gut health, etc.) that can trigger or exacerbate these conditions. This resource unpacks many different tools and practical treatment options that should be on the radar of patients living with these (and other) chronic conditions. When faced with these labels, it can be overwhelming to weed through all the resources out there to figure out how to move forward with a comprehensive and personalized road map. By helping readers put it all together in an organized manner, this book is a great resource for any patient with chronic illness as well as the caregivers and doctors who support them.

Mast Cells and Basophils

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Publisher : John Wiley & Sons
ISBN 13 : 0470030518
Total Pages : 274 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Mast Cells and Basophils by : Derek J. Chadwick

Download or read book Mast Cells and Basophils written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2006-01-04 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic possibilities for the treatment of diseases such as allergic inflammation and autoimmune disease which are mediated, in part, by these granulocytes.

Advances in Mast Cell Physiology and Mast Cell-Driven Diseases

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Publisher : Frontiers Media SA
ISBN 13 : 2832538541
Total Pages : 157 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Advances in Mast Cell Physiology and Mast Cell-Driven Diseases by : Carlo Pucillo

Download or read book Advances in Mast Cell Physiology and Mast Cell-Driven Diseases written by Carlo Pucillo and published by Frontiers Media SA. This book was released on 2023-11-22 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast cells (MCs) are tissue-resident, innate immune cells with heterogenous phenotypes imprinted by cytokines, growth factors, and other stimuli in their immediate microenvironment. Populating tissues in several waves including during fetal development, in adults bone marrow-derived progenitor cells circulate in the blood and migrate and differentiate into mature MCs in tissue. MCs are abundantly present in the skin and mucosal tissues but can be found in virtually all organs often increasing in numbers during inflammation. MCs are key effectors in IgE-associated immune responses, including allergic disorders and associated protective immune responses. They release a variety of mediators acting on immune and non-immune cells, including nerve cells, fibroblasts, endothelial cells, smooth muscle cells, and epithelial cells. MCs, via the expression of numerous other receptors, can be triggered by many other stimuli including TLR ligands, complement, and neuropeptides etc. Playing a protective role in parasitic, bacterial, and viral infections but also venom and toxin neutralization, MCs are best known for their role in the pathogenesis of allergic diseases. Several lines of evidence have implicated MCs in the development of autoimmune diseases and a whole variety of chronic inflammatory disorders, including cardiovascular diseases, urticaria, mastocytosis, and several cancers. The manifestations of MC-driven disease are considered to be a consequence of an inappropriate activation of MC immune responses which have evolved to protect the body against a host of pathogens and perhaps toxins.

A brief history of Bishop Jacob Mast and other Mast pioneers

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Author :
Publisher : Рипол Классик
ISBN 13 : 5873929858
Total Pages : 823 pages
Book Rating : 4.8/5 (739 download)

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Book Synopsis A brief history of Bishop Jacob Mast and other Mast pioneers by : C. Z. Mast

Download or read book A brief history of Bishop Jacob Mast and other Mast pioneers written by C. Z. Mast and published by Рипол Классик. This book was released on 1911 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: with Biographies of their Descendants from the earliest available records to the present time; with Portraits and other illustrations.

My Year Before the Mast

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Publisher : Dundurn
ISBN 13 : 1554882370
Total Pages : 229 pages
Book Rating : 4.5/5 (548 download)

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Book Synopsis My Year Before the Mast by : Annette Brock Davis

Download or read book My Year Before the Mast written by Annette Brock Davis and published by Dundurn. This book was released on 1999-04-01 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1933, a young Canadian woman rejected the expectations of society and her upper-class family and became a crew member aboard one of the last great four-masted sailing vessels that still plied the ocean. It was not an easy task. Young Annette had to fight pressures from her family, rejection from schools of navigation, and doubts from ship owners. When she finally found a berth as an apprentice seaman, she faced hostility from officers and crew, who grumbled that she should be home "raising babies." In the end, however, Annette won their respect, taking in sails, standing night watches, hauling and coiling ropes all the tasks the men were doing, with no concession to a girl’s lesser strength. My Year Before the Mast tells the story of Annette Brock Davis’s life on the sea as the first female crew member of a commercial sailing line. Her courage and determination to break into a closed male world are central to this book, but we cannot ignore the fact that, while this is a book about a woman’s struggle, it is also a book about the sea. Davis brings to life an era long gone, and introduces an incredible cast of characters the crew, officers, and passengers, each with his own foibles, humour, generosity, and flashes of meanness. But through it all, Annette emerges as the most remarkable character of them all.

Mast Cell Proteases in Immunology and Biology

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Publisher : CRC Press
ISBN 13 : 9780824794842
Total Pages : 380 pages
Book Rating : 4.7/5 (948 download)

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Book Synopsis Mast Cell Proteases in Immunology and Biology by : Caughey

Download or read book Mast Cell Proteases in Immunology and Biology written by Caughey and published by CRC Press. This book was released on 1995-05-11 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art reference provides timely and clinically and experimentally useful information on the major proteins of mast cell secretory granules that are released into the lung, skin, gut, eye, and other tissues under the influence of diverse stimuli-including cytokines, growth factors, neuropeptides, and allergen-bound immunoglobulin E. Demonstrates the important roles proteases play in the maintenance of tissue homeostasis as well as in the damaging events linked with allergy and other varieties of inflammation!

Rudimentary Treatise on Masting, Mast-making, and Rigging of Ships ... [With Illustrations.]

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Publisher :
ISBN 13 :
Total Pages : 198 pages
Book Rating : 4.R/5 (6 download)

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Book Synopsis Rudimentary Treatise on Masting, Mast-making, and Rigging of Ships ... [With Illustrations.] by : Robert Kipping

Download or read book Rudimentary Treatise on Masting, Mast-making, and Rigging of Ships ... [With Illustrations.] written by Robert Kipping and published by . This book was released on 1864 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Role of Mast Cells in Immediate Hypersensitivity Reactions

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889718174
Total Pages : 114 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The Role of Mast Cells in Immediate Hypersensitivity Reactions by : Marcelo Vivolo Aun

Download or read book The Role of Mast Cells in Immediate Hypersensitivity Reactions written by Marcelo Vivolo Aun and published by Frontiers Media SA. This book was released on 2021-12-06 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: