A Highly Sensitive SERS Sensor for Quantitative Analysis of Glucose Based on the Chemical Etching of Silver Nanoparticles

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ISBN 13 :
Total Pages : pages
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Book Synopsis A Highly Sensitive SERS Sensor for Quantitative Analysis of Glucose Based on the Chemical Etching of Silver Nanoparticles by :

Download or read book A Highly Sensitive SERS Sensor for Quantitative Analysis of Glucose Based on the Chemical Etching of Silver Nanoparticles written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis

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Publisher : Springer
ISBN 13 : 3662563339
Total Pages : 592 pages
Book Rating : 4.6/5 (625 download)

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Book Synopsis Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis by : Challa S.S.R. Kumar

Download or read book Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis written by Challa S.S.R. Kumar and published by Springer. This book was released on 2018-05-02 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eighth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Highly Sensitive Sers Immunosensor Via Extrinsic Nano-stress Sensing

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ISBN 13 : 9780438640412
Total Pages : 57 pages
Book Rating : 4.6/5 (44 download)

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Book Synopsis Highly Sensitive Sers Immunosensor Via Extrinsic Nano-stress Sensing by : Leonard James Apontti

Download or read book Highly Sensitive Sers Immunosensor Via Extrinsic Nano-stress Sensing written by Leonard James Apontti and published by . This book was released on 2018 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors have begun to attract and find widespread use in the medical field due to their potential for ultrasensitive detection, and as a reliable, high-throughput, and nondestructive diagnostic immunoassay, specifically aimed towards the early screening of cancer. Specifically, there is need to screen the early stages of tumor growth, as 90% of all cancer related deaths are due to metastasis. Matrix metalloproteinase-14 (MMP-14) is an important target for cancer research due to its ability to induce tissue remodeling, extracellular matrix degradation, tumor invasion and angiogenesis. Surface Enhanced Raman Spectroscopy (SERS) has emerged as a popular method of detection due to the high optical enhancement offered by the surface plasmon resonances (SPRs) of metallic nanostructures while preserving the structural specificity, rapid screening, and high flexibility of Raman spectroscopy. The direct SERS analysis of biomolecules often suffer from poor selectivity and sensitivity due to their weak Raman activities, lack of characteristic functional groups/polarizable moieties, and poor surface selection rules with the nanoparticle surface. This study hopes to take advantage of a novel indirect approach termed "nano-stress" sensing which provides an excellent alternative to conventional direct sensing. In short, a Raman reporter with a highly resolved, well characterized spectrum is chemically functionalized with a biorecognition element (e.g. antibodies) and undergoes a change in peak intensity or position in response to a molecular recognition event (e.g. antibody-antigen binding). Chapter 2 describes the synthesis of silver octahedral nanoparticles using a modified polyol process and their assembly into a large-scale, close-packed, two-dimensional, thin film SERS platform, using a homemade Langmuir-Blodgett (LB) trough. SEM images reveal many well-ordered, close-packed polycrystalline domains scattered throughout. Chapter 3 presents the fabrication of the SERS immunosensor using a self-assembled monolayer (SAM) of 4-MBA, its chemical modification to bind to Fab3A2, and the detection of cdMMP-14 through extrinsic nano-stress sensing. Optimization experiments using TRIS Buffer indicate that a 0.1M/0.1M EDC/NHS solution at pH 6.0 with stirring gives the highest 4-MBA conjugation (~50%). About 38.58% Fab3A2 conjugation was observed along with the successful sensing of the biorecognition event between Fab3A2 and cdMMP-14 at various concentrations. A maximum frequency shift of 0.95±0.37cm-1 was observed for 5x10 -7M cdMMP-14. A linear semilog relationship (R2=97.79%) was also observed giving the equation y = 0.31136x + 2.9109 for the concentration range 5x10-7M to 5x10-10M. Control experiments shows slight to relatively no binding with cdMMP-9 as well as minimal non-specific protein adsorption therefore confirming the specificity of the immunosensor.

Glucose Sensing

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Publisher : Springer Science & Business Media
ISBN 13 : 0387330151
Total Pages : 460 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Glucose Sensing by : Chris D. Geddes

Download or read book Glucose Sensing written by Chris D. Geddes and published by Springer Science & Business Media. This book was released on 2007-12-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.

Rational Design of SERS Active Silica Coated Silver Nanoparticles as a Versatile Platform for Semi-quantitative Bio-imaging

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)

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Book Synopsis Rational Design of SERS Active Silica Coated Silver Nanoparticles as a Versatile Platform for Semi-quantitative Bio-imaging by : Louise Rocks

Download or read book Rational Design of SERS Active Silica Coated Silver Nanoparticles as a Versatile Platform for Semi-quantitative Bio-imaging written by Louise Rocks and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there has been an increased demand for real-time detection of specific biological species and interactions within a meaningful environment. Surface enhanced Raman scattering (SERS) from metallic nanoparticles represents an approach under development with added advantages over fluorescence. One such benefit is the narrower vibrational bands in SERS compared to fluorescence which increases potential for simultaneous detection of more than one species. The use of metallic nanoparticles in Raman enhancement is hindered by non-specific adsorption of contaminating species and uncontrolled aggregation in vivo. Silica encapsulation of the nanoparticles results in a biocompatible and robust substrate with consistent surface chemistry. While gold nanoparticles have been shelled in silica by many different methods, transfer of encapsulation methods to silver has not been possible due to the reduced chemical stability of silver. New surface chemistries are therefore required to achieve reproducible, silica encapsulated silver nanoparticles. Tri-functional molecules were synthesised which stabilise the silver nanoparticle core, act as (resonance) Raman reporters and provide suitable precursors for subsequent silica encapsulation. Subsequent bio-functionalisation of these nanoparticles, by covalent attachment of proteins, generates SERS active bioimaging nanoparticles. Raman mapping of biological samples has been used for ex vivo detection and imaging of the inflammatory marker tumour necrosis factor. Semi-quantitative discrimination, of cerebral tissue sections, was achieved between mice infected with experimental cerebral malaria and uninfected controls. These results were produced using both 632.8 nm and 514.5 nm excitation wavelengths. In this work, a sensitive SERS based approach to biomolecule imaging has been developed. Successful targeting of TNF using silver nanoparticles, and excitation wavelengths in the visible region, may provide advantages over the use of gold in a wide range of SERS based applications.

Nanobiosensors

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Publisher : Academic Press
ISBN 13 : 0128043725
Total Pages : 928 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nanobiosensors by : Alexandru Grumezescu

Download or read book Nanobiosensors written by Alexandru Grumezescu and published by Academic Press. This book was released on 2016-09-28 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobiosensors: Nanotechnology in the Agri-Food Industry, Volume 8, provides the latest information on the increasing demand for robust, rapid, inexpensive, and safe alternative technologies that monitor, test, and detect harmful or potentially dangerous foods. Due to their high sensitivity and selectivity, nanobiosensors have attracted attention for their use in monitoring not only biological contaminants in food, but also potential chemical and physical hazards. This book offers a broad overview regarding the current progress made in the field of nanosensors, including cutting-edge technological progress and the impact of these devices on the food industry. Special attention is given to the detection of microbial contaminants and harmful metabolotes, such as toxins and hormones, which have a great impact on both humans and animal health and feed. - Includes the most up-to-date information on nanoparticles based biosensors and quantum dots for biological detection - Provides application methods and techniques for research analysis for bacteriological detection and food testing - Presents studies using analytical tools to improve food safety and quality analysis

Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions

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Publisher : Springer Nature
ISBN 13 : 3030761797
Total Pages : 256 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions by : Carlos G. Juan

Download or read book Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions written by Carlos G. Juan and published by Springer Nature. This book was released on 2021-06-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive study covering the design and application of microwave sensors for glucose concentration detection, with a special focus on glucose concentration tracking in watery and biological solutions. This book is based on the idea that changes in the glucose concentration provoke variations in the dielectric permittivity of the medium. Sensors whose electrical response is sensitive to the dielectric permittivity of the surrounding media should be able to perform as glucose concentration trackers. At first, this book offers an in-depth study of the dielectric permittivity of water–glucose solutions at concentrations relevant for diabetes purposes; in turn, it presents guidelines for designing suitable microwave resonators, which are then tested in both water–glucose solutions and multi-component human blood plasma solutions for their detection ability and sensitivities. Finally, a portable version is developed and tested on a large number of individuals in a real clinical scenario. All in all, the book reports on a comprehensive study on glucose monitoring devices based on microwave sensors. It covers in depth the theoretical background, provides extensive design guidelines to maximize sensitivity, and validates a portable device for applications in clinical settings.

A 3D SERS Device for Highly Sensitive Detection of Organic Chemicals in Liquid

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ISBN 13 :
Total Pages : 84 pages
Book Rating : 4.:/5 (132 download)

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Book Synopsis A 3D SERS Device for Highly Sensitive Detection of Organic Chemicals in Liquid by : Sankgeeth Vennila Sigamani

Download or read book A 3D SERS Device for Highly Sensitive Detection of Organic Chemicals in Liquid written by Sankgeeth Vennila Sigamani and published by . This book was released on 2021 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detection of organic chemicals in liquid medium have been gaining utmost attention in recent times. Real time detection and monitoring of a variety of environmental pollutants, explosive materials, chemical agents,and pharmaceutical drugs in liquid medium are of great need in today's technological advancements. While there are several scattering, emission and spectroscopy techniques in use, Raman spectroscopy is attractive because of its molecular specificity i.e., each molecule has a Raman fingerprint. Raman spectroscopy utilizes the inelastic portion of the scattered wave for detection. But since intensity of inelastic scattering (Raman scattering) is very low, compared to the elastic scattering, low concentration analysis has been challenging. Surface-Enhanced Raman spectroscopy or Surface-Enhanced Raman Scattering (SERS) potentially overcomes this challenge, with its good detection capabilities for lower concentrations in liquid solution. SERS enhances the Raman signal of molecules (capable of 1010-fold enhancement) when they are adsorbed on a metal nanostructure (termed as SERS substrate) surface. The design of SERS substrate plays a crucial part in the enhancement of the Raman signal. Conventional 2D substrates are not very efficient in providing binding of the analyte molecules to SERS sensitive hotspots and in-situ detection can be challenging, owing to the low volume of liquid on the surface. These challenges can be overcome by using three-dimensional (3D) hierarchical nanostructures as SERS substrates, because of its high hotspot density along all spatial directions.Single crystal 3D silver dendrites are desirable for such application,due to the presence of nanotips and nanogaps which act as hotspots enhancing the Raman signal. These silver nano dendrites can be generated by a simple Galvanic Replacement Reaction (GRR) between copper wire and silver nitrate solution, yielding a multi-level branched nanostructure. These branched surfaces in proximity, have the capability to enhance the Raman signal of the analyte present, due to Localized Surface Plasmon Resonance effect (LSPR).In this thesis, a reliable, reusable and low-cost SERS device,employing 3D silver nano dendrites, that can be used for in-situ monitoring of organic molecules in liquid flows is presented. This device has the capability to detect very low concentrations of organic chemicals, at parts per million range in liquid in real time, without much of an erroneous measurement and sample preparation. The device was made of 3D silver nano-dendrites enclosed in channels in PDMS. It is reusable, with good reproducibility and has the potential for multichannel configurations that can provide parallel analysis. This device is made reliable by calibrating using Rhodamine-6g, as a reference molecule. It can be then used to detect various Raman active molecules in liquid solution with varying concentrations. We detected molecules of 4-Mercaptobenzoic Acid (4- MBA) and Methylene blue in liquid solutions with very low concentrations. Detection of Acetaminophen and Thiabendazole with good reproducibility, makes the device to have significant potentials at real-world applications in different fields. The device was successful in detecting ultra-low concentrations with high sensitivity, as compared to previously reported nano substrates thus making it a significant SERS substrate.

Surface-Enhanced Vibrational Spectroscopy

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Publisher : John Wiley & Sons
ISBN 13 : 9780470035658
Total Pages : 260 pages
Book Rating : 4.0/5 (356 download)

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Book Synopsis Surface-Enhanced Vibrational Spectroscopy by : Ricardo Aroca

Download or read book Surface-Enhanced Vibrational Spectroscopy written by Ricardo Aroca and published by John Wiley & Sons. This book was released on 2006-05-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Enhanced Vibrational Spectroscopy (SEVS) has reached maturity as an analytical technique, but until now there has been no single work that describes the theory and experiments of SEVS. This book combines the two important techniques of surface-enhanced Raman scattering (SERS) and surface-enhanced infrared (SEIR) into one text that serves as the definitive resource on SEVS. Discusses both the theory and the applications of SEVS and provides an up-to-date study of the state of the art Offers interpretations of SEVS spectra for practicing analysts Discusses interpretation of SEVS spectra, which can often be very different to the non-enhanced spectrum - aids the practicing analyst

Electrochemical Sensing for Food Quality and Safety

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (865 download)

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Book Synopsis Electrochemical Sensing for Food Quality and Safety by :

Download or read book Electrochemical Sensing for Food Quality and Safety written by and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An electrochemical sensor is a self-contained integrated device capable of generating specific quantitative or semi-quantitative analytical signals based on a biological or chemical recognition element/receptor in combination with an electrochemical transduction element. Electrochemical analytical sensors are used a wide range of industries such as pharmaceutical, healthcare, food, agriculture, environment and water. Food and drink industries are in need for reliable detection technologies to assure product quality, monitor deleterious ingredients and contaminants and process control. Electrochemical sensors afford such promising applications in food processing and quality control owing to their simplicity, rapidity, affordability and miniaturization for on-site detection. Carbon, as an array of atoms in certain structural forms, exists as diamond, graphite, graphene, fullerenes, carbon nanotubes and amorphous carbon (soft, hard, diamond-like or graphitic carbon) with a number of appealing properties for different purposes. This group of materials is being used in the construction of biosensors as transducers, immobilization matrices, stabilizers, and mediators. In this thesis, different carbon or carbon hybrid based electrochemical biosensors are developed for detection of food ingredients and additives such as sugars. Sugars are not only extensively involved in the production of thousands of food products from cured meat through preserves and frozen fruits to confections, but also directly related to human health such as obesity, glycemic index, metabolism and diseases. The most known health problem is diabetes which is associated with elevated glucose (Glc) level in blood and sometimes in urine and it is yet completely cured as a chronic disease. Several enzyme-free electrochemical sensors were developed for detection of Glc based on different carbon hybrid nanocomposite materials. Vertically well-aligned multi-walled carbonnanotubes (MWCNTs) were firstly synthesized by chemical vapor deposition (CVD) on a tantalum (Ta) foil substrate using a thin layer of magnetron-sputtered cobalt (Co) as catalyst. The as-synthesized MWCNTs were then modified with copper nanoparticles or cobalt oxide/hydroxide nanoparticles. The modified nanocomposites exhibit much higher electrocatalytic activity towards Glc than before modification, with a high sensitivity, fast response time, wide linear range, low detection limit (at signal/noise ratio=3) and long-term stability for weeks. In another work, a facile one-step approach is used to directly deposit chitosan-reduced graphene oxide-nickel nanoparticle (CS-ERGO-NiNPs) composites onto a screen-printed carbon electrode (SPE) with outstanding analytical performances. A microfluidic electrochemical device with polydimethylsiloxane(PDMS) chambers and acrylonitrile butadiene styrene (ABS) plastic holders was fabricated to feature the as-synthesized SPE sensor. Enzymatic electrochemical biosensors were also developed. The first sensor was based on electrochemically-reduced graphene oxide (ERGO) modified with heterogeneous bimetallic gold-palladium (AuPd) nanoparticles, and the as-synthesized material showed extraordinary sensitivity and stability towards oxygen reduction. A biosensor was then constructed by immobilizing glucose oxidase (GOx) as a model enzyme on the nanocomposites for glucose detection through oxygen consumption during the enzymatic reaction and thus this type of sensor is basically suitable for any oxidase-based biosensing. The second enzymatic sensor was fabricated based on platinum nanoparticles (PtNPs)-modified SPE and enzyme-immobilized cellulose paper and the detection was achieved by detection of the hydrogen peroxide (H2O2) generated in the enzymatic reaction which is different from the first sensor. The enzyme-modified paper showed better mechanical properties and the paper fluidic device has many advantages in sensing such as reagent storage, sample delivery, concentration and low cost. Moreover, a disposable indium tin oxide-coated glass (ITO) working electrode was modified by gold nanoparticles (AuNPs)-ERGO for quick detection of lean meat powder compounds in meat samples at low cost for clinical diagnostic and therapeutic purposes as well as to prevent possible illegal use in animal feed. The neurotransmitter dopamine (4-(2-aminoethyl)benzene-1,2-diol) (DA) can be detected using the one-time-use electrode by either amperometry or differential pulse voltammetry (DPV). The electrochemical catalysis of DA was proven to be a surface process and correlates well with the conventional UV-vis spectrophotometric approach but with more than thrice the dynamic range. The sensor also exhibited good stability and capability to detect DA in beef samples, and thus is a promising candidate for simple and inexpensive sub-nanomolar detection of DA, especially in the presence of UV-absorbing compounds. Lastly, a novel and facile approach was developed to synthesize thin films of magnetite (Fe3O4) with epitaxial needle-like columnar grains on titanium nitride (TiN) buffered substrate using DC magnetron reactive sputtering. The electrocatalytic activity of the epitaxial peroxidase-mimetic Fe3O4 thin-film sensor against H2O2 reduction was rapid with a response time less than 5 s. The sensor also exhibited an acceptable stability, a satisfactory sensitivity, good selectivity to the substrate, a dynamic working range and a low detection limit. The sensor performance correlated well (R2= 0.996) with results obtained using a commercial HPLC-UV device. The sensor performance was robust and accurate in measuring H2O2 in some complex food matrices. The advantages of relative simplicity and ease of mass production make the epitaxial Fe3O4 thin film promising candidate for use in sensing applications.

A Highly Sensitive and Selective Surface-Enhanced Nanobiosensor

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Publisher :
ISBN 13 :
Total Pages : 6 pages
Book Rating : 4.:/5 (742 download)

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Book Synopsis A Highly Sensitive and Selective Surface-Enhanced Nanobiosensor by : Amanda J. Haes

Download or read book A Highly Sensitive and Selective Surface-Enhanced Nanobiosensor written by Amanda J. Haes and published by . This book was released on 2002 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanosphere lithography (NSL) derived triangular Ag nanoparticles were used to create an extremely sensitive and specific optical biological and chemical nanosensor. Using simple UV-vis spectroscopy, biotinylated surface-confined Ag nanoparticles were used to detect streptavidin down to one picomolar concentrations. The system was tested for nonspecific binding interactions with bovine serum albumin and was found to display virtually no adverse results. The extremely sensitive and selective response of the Ag nanoparticle sensor indicates an exciting use for biological and chemical sensing.

Truly Non Invasive Glucose Optical Sensor Based on Metal Nanoparticles Generation

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Publisher :
ISBN 13 :
Total Pages : 41 pages
Book Rating : 4.:/5 (979 download)

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Book Synopsis Truly Non Invasive Glucose Optical Sensor Based on Metal Nanoparticles Generation by : Marisol Garcia

Download or read book Truly Non Invasive Glucose Optical Sensor Based on Metal Nanoparticles Generation written by Marisol Garcia and published by . This book was released on 2006 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is a disease that causes many complications in human normal function. This disease represents the sixth-leading cause of death in USA. Prevention of diabetes-related complications can be accomplished through tight control of glucose levels in blood. In the last decades many different glucose sensors have been developed, however, none of them are really non invasive. Herein, we present the study of the application of gold and silver nanoparticles with different shapes and aspect ratios to detect glucose traces in human fluids such as tears and sweat. This is to our knowledge the first truly non invasive glucose optical sensor, with extraordinary limit of detection and selectivity. The best proven nanoparticles for this application were gold nanospheres. Gold nanospheres were synthesized using chloroauric acid tri-hydrated (HAuCl4.3H2O) in solution, in the presence of glucose and ammonia hydroxide. The higher the glucose concentration, the higher the number of nanoparticles generated, thus the higher the extinction efficiency of the solution. The linear dependence of the extinction efficiency of the gold nanoparticles solution with glucose concentration makes of this new sensor suitable for direct applications in biomedical sensing. Our approach is based on the well known Tollens test.

Functional Nanomaterials and their Applications

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Publisher : Trans Tech Publications Ltd
ISBN 13 : 3038260819
Total Pages : 270 pages
Book Rating : 4.0/5 (382 download)

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Book Synopsis Functional Nanomaterials and their Applications by : Hardev Singh Virk

Download or read book Functional Nanomaterials and their Applications written by Hardev Singh Virk and published by Trans Tech Publications Ltd. This book was released on 2013-05-14 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume is indexed by Thomson Reuters BCI (WoS). Functional nanomaterials are the basis of newly emerging nanotechnologies for various device applications. Nanomaterials with many kinds of morphologies and compositions have been extensively investigated, and display various kinds of functionality in areas such as electronic structure, optical effects, spin dynamics, and gas sensing. Because of advanced characterization and new fabrication techniques, nanomaterials are now central to multiple disciplines, including materials science, chemistry, physics, engineering and medicine. This special volume presents a detailed overview of recent research developments on functional nanomaterials, including synthesis, characterization, and applications.

Sers-active Silver Nanoparticle Arrays on Track Etch Membrane Support as Flow-through Water Quality Sensors

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (129 download)

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Book Synopsis Sers-active Silver Nanoparticle Arrays on Track Etch Membrane Support as Flow-through Water Quality Sensors by : Julian S. Taurozzi

Download or read book Sers-active Silver Nanoparticle Arrays on Track Etch Membrane Support as Flow-through Water Quality Sensors written by Julian S. Taurozzi and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Non-enzymatic Glucose Sensors Based on Laser-induced Graphene Integrated with Skin-interfaced Microfluidic Component for On-body Measurement

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (133 download)

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Book Synopsis Non-enzymatic Glucose Sensors Based on Laser-induced Graphene Integrated with Skin-interfaced Microfluidic Component for On-body Measurement by : Shangbin Liu

Download or read book Non-enzymatic Glucose Sensors Based on Laser-induced Graphene Integrated with Skin-interfaced Microfluidic Component for On-body Measurement written by Shangbin Liu and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent increased interest in wearable and mobile technologies has prompted increasing research efforts in developing non-invasive glucose monitoring platforms. In comparison with enzymatic glucose sensors, non-enzymatic glucose sensors have low cost, high stability, and easy integration and have the potential to be wearable real-time monitoring sensors. However, due to the trace amount of glucose in sweat, the sensitivity of existing non-enzymatic glucose sensors still needs to be further improved. To demonstrate practical approaches with bimetals or 3D porous structures, the porous laser-induced graphene (LIG) on flexible polymers demonstrates good conductivity and a simple fabrication process to integrate sensing materials. The uniform electroless plating of the nickel and gold layer on LIG electrodes demonstrates significantly enhanced sensitivity and an extensive linear range for glucose sensing. The sensor with the porous LIG foam exhibits a high sensitivity of 1080 [mu]A·mM-1·cm-2 , whereas a further increased sensitivity of 3500 [mu]A·mM-1·cm-2 is obtained with LIG fibers (LIGF). Impressively, a significant linear range (0--30 mM) can be achieved by changing the bias voltage from 0.5 to 0.1 V due to the Au coating. In order to store and evaluate the sweat content of sweat on the skin, this work integrates a porous encapsulated reaction chamber with an alkaline solution containing an alkaline solution with a soft, skin-interface microfluidic component. In addition, we tested glucose levels in human sweat and cell culture media before and after meals using the amperometric response of the sensor that demonstrates non-enzymatic sweat glucose biosensors are expected to be the prospect of commercial wearable devices.

Comprehensive Foodomics

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Publisher : Elsevier
ISBN 13 : 0128163968
Total Pages : 2444 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Comprehensive Foodomics by :

Download or read book Comprehensive Foodomics written by and published by Elsevier. This book was released on 2020-11-12 with total page 2444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josic, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljevic Pavelic, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain Brings all relevant foodomics information together in one place, offering readers a ‘one-stop,’ comprehensive resource for access to a wealth of information Includes articles written by academics and practitioners from various fields and regions Provides an ideal resource for students, researchers and professionals who need to find relevant information quickly and easily Includes content from high quality authors from across the globe

Metal Nanoparticles in Microbiology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642183123
Total Pages : 306 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Metal Nanoparticles in Microbiology by : Mahendra Rai

Download or read book Metal Nanoparticles in Microbiology written by Mahendra Rai and published by Springer Science & Business Media. This book was released on 2011-04-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.