A Guide to Safety in the Pharmaceutical or Chemical Industry

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Author :
Publisher : Kindle Direct Publishing
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.8/5 (642 download)

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Book Synopsis A Guide to Safety in the Pharmaceutical or Chemical Industry by : Dr. Shmmon Ahmad

Download or read book A Guide to Safety in the Pharmaceutical or Chemical Industry written by Dr. Shmmon Ahmad and published by Kindle Direct Publishing. This book was released on 2023-10-14 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: After many years of industrial experience in the Pharmaceutical Industry, serving as a Quality Assurance Officer and Production Officer, I felt compelled to share my insights. Throughout my career in various manufacturing companies, I witnessed a series of mishaps, accidents, injuries, near misses, fires, and other incidents that underscored a critical issue. It became evident that even seasoned safety professionals often lacked a comprehensive understanding of the techniques, terminology, procedures, and systems essential for assessing, measuring, and applying the necessary tools to achieve the desired safety performance. My journey eventually led me to the role of an educator at Glocal University Saharanpur, where I taught Quality Assurance subjects. In my opinion, these subjects require continuous evaluation and updating to remain relevant in an ever-evolving industrial landscape. I firmly believe that certain topics hold paramount importance, particularly for safety professionals and management personnel responsible for safety management within their organizations. This book delves into topics such as management responsibility, attitudinal problems, behaviour, safety thinking, motivation for creating a safety culture, and communication challenges. These subjects are approached from a practical standpoint, making them readily applicable to day-to-day safety administration. While extensive information and literature exist on motivation and communication, their specific applications in the realm of occupational safety and loss prevention are relatively scarce. I aspire to offer this book as a valuable resource to safety professionals, safety advisors and representatives, and industry line managers to improving plant facility design, training for operation and maintenance staff, and the development of safe operating procedures. Its purpose is to unravel what has gone wrong in the past and provide guidance on preventing similar incidents in the future. Regrettably, history has shown that many incidents tend to recur after a few months, often due to people moving on and lessons being forgotten. Among the various teaching methods, experiential learning has proven the most effective, as it helps retain subject matter for an extended period. Should you come across an incident described in this book that appears to have taken place in your plant, please be aware that certain details may have been altered. This alteration is intended to make it challenging for readers to pinpoint the exact location of the incident or to simplify complex narratives without compromising the core message. In some cases, the incident may not have occurred in your plant at all; it may have taken place in a different facility facing similar circumstances."

Safe Use of Chemicals

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Publisher : CRC Press
ISBN 13 : 1420080520
Total Pages : 310 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Safe Use of Chemicals by : T.S.S. Dikshith

Download or read book Safe Use of Chemicals written by T.S.S. Dikshith and published by CRC Press. This book was released on 2008-08-21 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Occupational workers frequently use, store, and dispose of toxic chemicals without knowing the possible consequences, both for the workplace and the environment. Improper use or misuse of chemical substances can result in health disorders, fatalities, or chemical disasters. Safe Use of Chemicals: A Practical Guide presents quick and comprehensive i

Chemical Laboratory Safety and Security

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Publisher : National Academies Press
ISBN 13 : 0309392209
Total Pages : 117 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Chemical Laboratory Safety and Security by : National Academies of Sciences, Engineering, and Medicine

Download or read book Chemical Laboratory Safety and Security written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-08-07 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. Department of State charged the Academies with the task of producing a protocol for development of standard operating procedures (SOPs) that would serve as a complement to the Chemical Laboratory Safety and Security: A Guide to Prudent Chemical Management and be included with the other materials in the 2010 toolkit. To accomplish this task, a committee with experience and knowledge in good chemical safety and security practices in academic and industrial laboratories with awareness of international standards and regulations was formed. The hope is that this toolkit expansion product will enhance the use of the previous reference book and the accompanying toolkit, especially in developing countries where safety resources are scarce and experience of operators and end-users may be limited.

Guidelines for Risk Based Process Safety

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Publisher : John Wiley & Sons
ISBN 13 : 111820963X
Total Pages : 761 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Guidelines for Risk Based Process Safety by : CCPS (Center for Chemical Process Safety)

Download or read book Guidelines for Risk Based Process Safety written by CCPS (Center for Chemical Process Safety) and published by John Wiley & Sons. This book was released on 2011-11-30 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guidelines for Risk Based Process Safety provides guidelines for industries that manufacture, consume, or handle chemicals, by focusing on new ways to design, correct, or improve process safety management practices. This new framework for thinking about process safety builds upon the original process safety management ideas published in the early 1990s, integrates industry lessons learned over the intervening years, utilizes applicable "total quality" principles (i.e., plan, do, check, act), and organizes it in a way that will be useful to all organizations - even those with relatively lower hazard activities - throughout the life-cycle of a company.

Chemical Engineering in the Pharmaceutical Industry

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Publisher : John Wiley & Sons
ISBN 13 : 111928550X
Total Pages : 1435 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : Mary T. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by Mary T. am Ende and published by John Wiley & Sons. This book was released on 2019-04-08 with total page 1435 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Chemical Engineering in the Pharmaceutical Industry

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Publisher : John Wiley & Sons
ISBN 13 : 1118088107
Total Pages : 1431 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : David J. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by David J. am Ende and published by John Wiley & Sons. This book was released on 2011-03-10 with total page 1431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences. Many of the experimental methods related to pharmaceutical process development are learned on the job. This book is intended to provide many of those important concepts that R&D Engineers and manufacturing Engineers should know and be familiar if they are going to be successful in the Pharmaceutical Industry. These include basic analytics for quantitation of reaction components– often skipped in ChE Reaction Engineering and kinetics books. In addition Chemical Engineering in the Pharmaceutical Industry introduces contemporary methods of data analysis for kinetic modeling and extends these concepts into Quality by Design strategies for regulatory filings. For the current professionals, in-silico process modeling tools that streamline experimental screening approaches is also new and presented here. Continuous flow processing, although mainstream for ChE, is unique in this context given the range of scales and the complex economics associated with transforming existing batch-plant capacity. The book will be split into four distinct yet related parts. These parts will address the fundamentals of analytical techniques for engineers, thermodynamic modeling, and finally provides an appendix with common engineering tools and examples of their applications.

Chemical Engineering in the Pharmaceutical Industry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119285860
Total Pages : 1172 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : David J. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by David J. am Ende and published by John Wiley & Sons. This book was released on 2019-04-23 with total page 1172 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the development and manufacturing of pharmaceutical products written for professionals in the industry, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry is a practical book that highlights chemistry and chemical engineering. The book’s regulatory quality strategies target the development and manufacturing of pharmaceutically active ingredients of pharmaceutical products. The expanded second edition contains revised content with many new case studies and additional example calculations that are of interest to chemical engineers. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The active pharmaceutical ingredients book puts the focus on the chemistry, chemical engineering, and unit operations specific to development and manufacturing of the active ingredients of the pharmaceutical product. The drug substance operations section includes information on chemical reactions, mixing, distillations, extractions, crystallizations, filtration, drying, and wet and dry milling. In addition, the book includes many applications of process modeling and modern software tools that are geared toward batch-scale and continuous drug substance pharmaceutical operations. This updated second edition: Contains 30new chapters or revised chapters specific to API, covering topics including: manufacturing quality by design, computational approaches, continuous manufacturing, crystallization and final form, process safety Expanded topics of scale-up, continuous processing, applications of thermodynamics and thermodynamic modeling, filtration and drying Presents updated and expanded example calculations Includes contributions from noted experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduate students, and professionals in the field of pharmaceutical sciences and manufacturing, the second edition of Chemical Engineering in the Pharmaceutical Industryf ocuses on the development and chemical engineering as well as operations specific to the design, formulation, and manufacture of drug substance and products.

Principles of Safety Pharmacology

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Publisher : Springer
ISBN 13 : 366246943X
Total Pages : 477 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Principles of Safety Pharmacology by : Michael K. Pugsley

Download or read book Principles of Safety Pharmacology written by Michael K. Pugsley and published by Springer. This book was released on 2015-06-19 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constitutes academic, pharmaceutical and biotechnology perspectives for Safety Pharmacology issues. Each chapter is written by an expert in the area and includes not only a fundamental background regarding the topic but also detailed descriptions of currently accepted, validated models and methods as well as innovative methodologies used in drug discovery.

Thermal Safety of Chemical Processes

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Publisher : John Wiley & Sons
ISBN 13 : 3527339213
Total Pages : 581 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Thermal Safety of Chemical Processes by : Francis Stoessel

Download or read book Thermal Safety of Chemical Processes written by Francis Stoessel and published by John Wiley & Sons. This book was released on 2021-05-24 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vollständig überarbeitete,aktualisierte 2. Auflage mit fünf neuen Kapiteln und den aktuellen IUPAC-Normen. Beschäftigt sich mit thermischen Risiken in der chemischen Prozessindustrie. Jedes Kapitel beginnt mit einer Fallstudie und den aus Zwischenfällen gewonnen Erkenntnissen.

Guidelines for Chemical Process Quantitative Risk Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 0470935413
Total Pages : 784 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Guidelines for Chemical Process Quantitative Risk Analysis by : CCPS (Center for Chemical Process Safety)

Download or read book Guidelines for Chemical Process Quantitative Risk Analysis written by CCPS (Center for Chemical Process Safety) and published by John Wiley & Sons. This book was released on 2010-08-27 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical process quantitative risk analysis (CPQRA) as applied to the CPI was first fully described in the first edition of this CCPS Guidelines book. This second edition is packed with information reflecting advances in this evolving methodology, and includes worked examples on a CD-ROM. CPQRA is used to identify incident scenarios and evaluate their risk by defining the probability of failure, the various consequences and the potential impact of those consequences. It is an invaluable methodology to evaluate these when qualitative analysis cannot provide adequate understanding and when more information is needed for risk management. This technique provides a means to evaluate acute hazards and alternative risk reduction strategies, and identify areas for cost-effective risk reduction. There are no simple answers when complex issues are concerned, but CPQRA2 offers a cogent, well-illustrated guide to applying these risk-analysis techniques, particularly to risk control studies. Special Details: Includes CD-ROM with example problems worked using Excel and Quattro Pro. For use with Windows 95, 98, and NT.

Guidelines for Inherently Safer Chemical Processes

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Publisher : John Wiley & Sons
ISBN 13 : 1119529220
Total Pages : 388 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Guidelines for Inherently Safer Chemical Processes by : CCPS (Center for Chemical Process Safety)

Download or read book Guidelines for Inherently Safer Chemical Processes written by CCPS (Center for Chemical Process Safety) and published by John Wiley & Sons. This book was released on 2019-10-16 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the second edition several United States jurisdictions have mandated consideration of inherently safer design for certain facilities. Notable examples are the inherently safer technology (IST) review requirement in the New Jersey Toxic Chemical Prevention Act (TCPA), and the Inherently Safer Systems Analysis (ISSA) required by the Contra Costa County (California) Industrial Safety Ordinance. More recently, similar requirements have been proposed at the U.S. Federal level in the pending EPA Risk Management Plan (RMP) revisions. Since the concept of inherently safer design applies globally, with its origins in the United Kingdom, the book will apply globally. The new edition builds on the same philosophy as the first two editions, but further clarifies the concept with recent research, practitioner observations, added examples and industry methods, and discussions of security and regulatory issues. Inherently Safer Chemical Processes presents a holistic approach to making the development, manufacture, and use of chemicals safer. The main goal of this book is to help guide the future state of chemical process evolution by illustrating and emphasizing the merits of integrating inherently safer design process-related research, development, and design into a comprehensive process that balances safety, capital, and environmental concerns throughout the life cycle of the process. It discusses strategies of how to: substitute more benign chemicals at the development stage, minimize risk in the transportation of chemicals, use safer processing methods at the manufacturing stage, and decommission a manufacturing plant so that what is left behind does not endanger the public or environment.

Bow Ties in Risk Management

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Publisher : John Wiley & Sons
ISBN 13 : 1119490391
Total Pages : 224 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Bow Ties in Risk Management by : CCPS (Center for Chemical Process Safety)

Download or read book Bow Ties in Risk Management written by CCPS (Center for Chemical Process Safety) and published by John Wiley & Sons. This book was released on 2018-10-09 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: AN AUTHORITATIVE GUIDE THAT EXPLAINS THE EFFECTIVENESS AND IMPLEMENTATION OF BOW TIE ANALYSIS, A QUALITATIVE RISK ASSESSMENT AND BARRIER MANAGEMENT METHODOLOGY From a collaborative effort of the Center for Chemical Process Safety (CCPS) and the Energy Institute (EI) comes an invaluable book that puts the focus on a specific qualitative risk management methodology – bow tie barrier analysis. The book contains practical advice for conducting an effective bow tie analysis and offers guidance for creating bow tie diagrams for process safety and risk management. Bow Ties in Risk Management clearly shows how bow tie analysis and diagrams fit into an overall process safety and risk management framework. Implementing the methods outlined in this book will improve the quality of bow tie analysis and bow tie diagrams across an organization and the industry. This important guide: Explains the proven concept of bow tie barrier analysis for the preventing and mitigation of incident pathways, especially related to major accidents Shows how to avoid common pitfalls and is filled with real-world examples Explains the practical application of the bow tie method throughout an organization Reveals how to treat human and organizational factors in a sound and practical manner Includes additional material available online Although this book is written primarily for anyone involved with or responsible for managing process safety risks, this book is applicable to anyone using bow tie risk management practices in other safety and environmental or Enterprise Risk Management applications. It is designed for a wide audience, from beginners with little to no background in barrier management, to experienced professionals who may already be familiar with bow ties, their elements, the methodology, and their relation to risk management. The missions of both the CCPS and EI include developing and disseminating knowledge, skills, and good practices to protect people, property and the environment by bringing the best knowledge and practices to industry, academia, governments and the public around the world through collective wisdom, tools, training and expertise. The CCPS has been at the forefront of documenting and sharing important process safety risk assessment methodologies for more than 30 years. The EI's Technical Work Program addresses the depth and breadth of the energy sector, from fuels and fuels distribution to health and safety, sustainability and the environment. The EI program provides cost-effective, value-adding knowledge on key current and future international issues affecting those in the energy sector.

Pharmaceutical Production

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Publisher : IChemE
ISBN 13 : 9780852954409
Total Pages : 500 pages
Book Rating : 4.9/5 (544 download)

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Book Synopsis Pharmaceutical Production by : Bill Bennett

Download or read book Pharmaceutical Production written by Bill Bennett and published by IChemE. This book was released on 2003 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is a general introduction aimed at all those involved in the engineering stages required for the manufacturr of the active ingredient and its dosage forms.

Safety in the Use of Chemicals at Work

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Author :
Publisher : International Labour Organization
ISBN 13 : 9789221080060
Total Pages : 116 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Safety in the Use of Chemicals at Work by : International Labour Office

Download or read book Safety in the Use of Chemicals at Work written by International Labour Office and published by International Labour Organization. This book was released on 1993 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This code of practice provides guidance on extablishing a systematic approach to safety in the use of chemicals at work. Intended for all those engaged in framing provisions, its recommendations are designed to ensure an efficient flow of information from manufacturers to users.

Pharmaceutical Process Development

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1849733074
Total Pages : 375 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Pharmaceutical Process Development by : John Blacker

Download or read book Pharmaceutical Process Development written by John Blacker and published by Royal Society of Chemistry. This book was released on 2011-08-17 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book provides a valuable overview of: both early and late stage chemical development, how safe and scaleable synthetic routes are designed, selected and developed, the importance of the chemical engineering, analytical and manufacturing interfaces, the key enabling technologies, including catalysis and biocatalysis, the importance of the green chemical perspective and solid form issues. The book, written and edited by experts in the field, is a contemporary, holistic treatise, with a logical sequence for process development and mini-case histories within the chapters to bring alive different aspects of the process. It is completely pharmaceutical themed, encompassing all essential aspects, from route and reagent selection to manufacture of the active compound. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry. It informs them about the breadth of the work carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. The book is also of value to academics who often understand the drug discovery arena, but have far less appreciation of the drug development area, and are thus unable to advise their students about the relative merits of careers in chemical development versus discovery.

Guidelines for Process Safety Documentation

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470938064
Total Pages : 416 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Guidelines for Process Safety Documentation by : CCPS (Center for Chemical Process Safety)

Download or read book Guidelines for Process Safety Documentation written by CCPS (Center for Chemical Process Safety) and published by John Wiley & Sons. This book was released on 2010-09-09 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The process industry has developed integrated process safety management programs to reduce or eliminate incidents and major consequences, such as injury, loss of life, property damage, environmental harm, and business interruption. Good documentation practices are a crucial part of retaining past knowledge and experience, and avoiding relearning old lessons. Following an introduction, which offers examples of how proper documentation might have prevented major explosions and serious incidents, the 21 sections in this book clearly present aims, goals, and methodology in all areas of documentation. The text contains examples of dozens of needed forms, lists of relevant industry organizations, sources for software, references, OSHA regulations, sample plans, and more.

Guidelines for Process Safety Metrics

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470572124
Total Pages : 202 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Guidelines for Process Safety Metrics by : CCPS (Center for Chemical Process Safety)

Download or read book Guidelines for Process Safety Metrics written by CCPS (Center for Chemical Process Safety) and published by John Wiley & Sons. This book was released on 2009-11-02 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Process safety metrics is a topic of frequent conversation within chemical industry associations. Guidelines for Process Safety Metrics provides basic information on process safety performance indicators, including a comprehensive list of metrics for measuring performance and examples as to how they can be successfully applied over both the short and long term. For engineers, insurers, corporate traininers, military personnel, government officials, students, and managers involved in production, product and process development, Guidelines for Process Safety Metrics can help determine appropriate metrics useful in monitoring performance and improving process safety programs. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.