A Functional View Of Smooth Muscle

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A Functional View of Smooth Muscle

Author : L. Barr
Publisher : Elsevier Science
ISBN 13 : 9780762306138
Total Pages : 0 pages
Book Rating : 4.3/5 (61 download)

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Book Synopsis A Functional View of Smooth Muscle by : L. Barr

Download or read book A Functional View of Smooth Muscle written by L. Barr and published by Elsevier Science. This book was released on 2000-10-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea of this volume was to provide for advanced graduate students, medical students, and postdoctoral who are beginning to do research related to smooth muscle a sampling of the orienting ideas of the researchers working on problems in smooth muscle physiology and pathophysiology. Therefore, an essential goal of the volume is to identify the lines of investigation that are currently being pursued by investigators whose concerns are with smooth muscle or with organs with parenchumal tissues consisting of smooth muscle. Various types of smooth muscle constitute the parenchuma or characteristic tissues of a large number of organs or regions of organs. In each case, the phenotype is distinctly different and, while smooth muscles do not exhibit the diversity of epithelia, they nevertheless span a great range of physiological responsiveness. Undoubtedly, the variations in the characteristic responses of different smooth muscles result from the expression of sets of transduction subserving proteins. However, it is what the sets are and how they work and are regulated that fascinated the physiologist. In this book, the contrast between sameness and diversity recurs as a theme.

Mechanisms of Vascular Disease

Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Anatomy and Physiology

Author : J. Gordon Betts
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anatomy & Physiology

Author : Lindsay Biga
Publisher :
ISBN 13 : 9781955101158
Total Pages : pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Anatomy & Physiology by : Lindsay Biga

Download or read book Anatomy & Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text

Cellular Aspects of Smooth Muscle Function

Author : C. Y. Kao
Publisher : Cambridge University Press
ISBN 13 : 9780521482103
Total Pages : 324 pages
Book Rating : 4.4/5 (821 download)

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Book Synopsis Cellular Aspects of Smooth Muscle Function by : C. Y. Kao

Download or read book Cellular Aspects of Smooth Muscle Function written by C. Y. Kao and published by Cambridge University Press. This book was released on 1997-08-28 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smooth muscles line many internal organs and, in general, are involved in moving fluids and slurry around the body. They are controlled by the action of hormones, by nervous stimulation, and can be influenced by drugs. This 1997 book provides a review of our understanding of smooth muscle and integrates molecular, cellular and physiological information with tissue and anatomical studies. Well-known researchers have written chapters giving detailed reviews of our current knowledge of the biochemistry, pharmacology, physiology and anatomy of smooth muscle. In particular, they cover the seven most important areas of smooth muscle function including morphology, electrophysiology, mechanisms of electromechanical and pharmacomechanical coupling, calcium homeostasis, signal transduction, mechanics of contraction, and the contractile proteins. All those interested in muscular contraction will find this book worthwhile, whether they are biochemists, physiologists, or cell biologists.

Colonic Motility

Author : Sushil K. Sarna
Publisher : Biota Publishing
ISBN 13 : 1615041516
Total Pages : 159 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Colonic Motility by : Sushil K. Sarna

Download or read book Colonic Motility written by Sushil K. Sarna and published by Biota Publishing. This book was released on 2010-11-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.

An Introduction to Smooth Muscle Mechanics (2nd Edition)

Author : Chun Y. Seow
Publisher : Cambridge Scholars Publishing
ISBN 13 : 152756228X
Total Pages : 189 pages
Book Rating : 4.5/5 (275 download)

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Book Synopsis An Introduction to Smooth Muscle Mechanics (2nd Edition) by : Chun Y. Seow

Download or read book An Introduction to Smooth Muscle Mechanics (2nd Edition) written by Chun Y. Seow and published by Cambridge Scholars Publishing. This book was released on 2020-11-13 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition is an updated version of an introductory level textbook intended for students who are interested in understanding the mechanical properties of smooth muscle. Compared with skeletal and cardiac muscles, smooth muscle is the least understood in terms of its contraction mechanism and the structure of its contractile apparatus. Nevertheless, it is an important tissue that is vital in many organ functions, such as blood pressure control, intestinal peristalsis, and the emptying of the bladder. Dysfunction of the muscle has been implicated in many diseases such as high blood pressure, asthma, and overactive bladders. This is the only book-length treatment of functional models of a variety of smooth muscle behaviors with their corresponding mathematical descriptions, and offers an easy-to-follow, step-by-step mathematical derivation that will help students to appreciate the muscle cell as a fine-tuned aggregate of mechanisms governed by the fundamental laws of physics. In addition to providing a detailed description of the known subcellular structure and mechanical function of the contractile apparatus of smooth muscle, it also covers experimentation techniques, instrumentation, and data analysis. The book is a must-have information source for anyone interested in smooth muscle cell ultrastructure, physiology, biochemistry, and pharmacology.

Respiratory Muscle Training

Author : Alison McConnell
Publisher : Elsevier Health Sciences
ISBN 13 : 0702054550
Total Pages : 403 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Respiratory Muscle Training by : Alison McConnell

Download or read book Respiratory Muscle Training written by Alison McConnell and published by Elsevier Health Sciences. This book was released on 2013-04-18 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Respiratory Muscle Training: theory and practice is the world’s first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts – theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge – and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. Introductory overviews of respiratory and exercise physiology, as well as training theory Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation Evidence-based guidance on the implementation of inspiratory muscle resistance training Over 150 functional exercises that incorporate a breathing challenge www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec’s RMT exercise module (via www.physiotec.ca)

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Signal Transduction and Smooth Muscle

Author : Mohamed Trebak
Publisher : CRC Press
ISBN 13 : 1498774237
Total Pages : 433 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Signal Transduction and Smooth Muscle by : Mohamed Trebak

Download or read book Signal Transduction and Smooth Muscle written by Mohamed Trebak and published by CRC Press. This book was released on 2018-08-06 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling. Key selling features: Focuses on smooth muscles of different types Describes ion channel signaling mechanisms Reviews calcium and receptor signaling Includes novel, cutting-edge methodologies Summarizes studies of mice with genetically encoding sensors in smooth muscle Chapter 9 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution (CC-BY) 4.0 license.

Keynes & Aidley's Nerve and Muscle

Author : Christopher L.-H. Huang
Publisher : Cambridge University Press
ISBN 13 : 1108495052
Total Pages : 327 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Keynes & Aidley's Nerve and Muscle by : Christopher L.-H. Huang

Download or read book Keynes & Aidley's Nerve and Muscle written by Christopher L.-H. Huang and published by Cambridge University Press. This book was released on 2020-11-19 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Editions previous to this one had R.D. Keynes and David J. Aidley as primary and secondary authors.

Skeletal Muscle Circulation

Author : Ronald J. Korthuis
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041834
Total Pages : 147 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Skeletal Muscle Circulation by : Ronald J. Korthuis

Download or read book Skeletal Muscle Circulation written by Ronald J. Korthuis and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References

Biochemistry of Smooth Muscle Contraction

Author : Michael Barany
Publisher : Elsevier
ISBN 13 : 0080527892
Total Pages : 455 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Biochemistry of Smooth Muscle Contraction by : Michael Barany

Download or read book Biochemistry of Smooth Muscle Contraction written by Michael Barany and published by Elsevier. This book was released on 1996-01-04 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.

Motor Function of the Pharynx, Esophagus, and Its Sphincters

Author : Ravinder Mittal
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615043330
Total Pages : 87 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Motor Function of the Pharynx, Esophagus, and Its Sphincters by : Ravinder Mittal

Download or read book Motor Function of the Pharynx, Esophagus, and Its Sphincters written by Ravinder Mittal and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deglutition or a swallow begins as a voluntary act in the oral cavity but proceeds autonomously in the pharynx and esophagus. Bilateral sequenced activation and inhibition of more than 25 pairs of muscles of mouth, pharynx, larynx, and esophagus is required during a swallow. A single swallow elicits peristalsis in the pharynx and esophagus along with relaxation of upper and lower esophageal sphincters. Multiple swallows, at closely spaced time intervals, demonstrate deglutitive inhibition; sphincters remain relaxed during the entire period, but only the last swallow elicits peristalsis. Laryngeal inlet closure or airway protection is very important during swallow. Upper part of the esophagus that includes upper esophageal sphincter is composed of skeletal muscles, middle esophagus is composed of a mixture of skeletal and smooth muscles, and lower esophagus, including lower esophageal sphincter, is composed of smooth muscles. Peristalsis progresses in seamless fashion, despite separate control mechanism, from the skeletal to smooth muscle esophagus. The esophagus's circular and longitudinal muscle layers contract synchronously during peristalsis. Sphincters maintain continuous tone; neuromuscular mechanisms for tonic closure in the upper and lower esophageal sphincters are different. Lower esophageal sphincter transient relaxation, belching mechanism, regurgitation, vomiting, and reflux are mediated via the brain stem. Table of Contents: Introduction / Central Program Generator and Brain Stem / Pharynx-Anatomy, Neural Innervation, and Motor Pattern / Upper Esophageal Sphincter / Neuromuscular Anatomy of Esophagus and Lower Esophageal Sphincter / Extrinsic Innervation: Parasympathetic and Sympathetic / Interstitial Cells of Cajal / Recording Techniques / Motor Patterns of the Esophagus-Aboral and Oral Transport / Deglutitive Inhibition and Muscle Refractoriness / Peristalsis in the Circular and Longitudinal Muscles of the Esophagus / Neural and Myogenic Mechanism of Peristalsis / Central Mechanism of Peristalsis-Cortical and Brain Stem Control / Peripheral Mechanisms of Peristalsis / Central Versus Peripheral Mechanism of Deglutitive Inhibition / Neural Control of Longitudinal Muscle Contraction / Modulation of Primary and Secondary Peristalsis / Neural Control of Lower Esophageal Sphincter and Crural Diaphragm / Lower Esophageal Sphincter / Swallow-Induced LES Relaxation / Crural Diaphragm Contribution to EGJ and Neural Control / Transient LES Relaxation and Pharmacological Inhibition / Compliance of the EGJ / References

Functional Somatic Symptoms in Children and Adolescents

Author : Kasia Kozlowska
Publisher : Springer Nature
ISBN 13 : 303046184X
Total Pages : 397 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Functional Somatic Symptoms in Children and Adolescents by : Kasia Kozlowska

Download or read book Functional Somatic Symptoms in Children and Adolescents written by Kasia Kozlowska and published by Springer Nature. This book was released on 2020-09-30 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system. This approach both provides a new understanding of how such symptoms emerge – typically, through a history of recurrent or chronic stress, either physical or psychological – and points the way to effective assessment, management, and treatment that put the child (and family) back on the road to health and well-being.

Muscle Development in Drosophilia

Author : Helen Sink
Publisher : Springer Science & Business Media
ISBN 13 : 0387329633
Total Pages : 214 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Muscle Development in Drosophilia by : Helen Sink

Download or read book Muscle Development in Drosophilia written by Helen Sink and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations. The book will appeal to those studying muscle development and muscle biology in any organism.

Wheater's Functional Histology

Author : Barbara Young
Publisher : Elsevier Health Sciences
ISBN 13 : 1437700756
Total Pages : 449 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Wheater's Functional Histology by : Barbara Young

Download or read book Wheater's Functional Histology written by Barbara Young and published by Elsevier Health Sciences. This book was released on 2006-03-31 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This best-selling atlas contains over 900 images and illustrations to help you learn and review the microstructure of human tissues. The book starts with a section on general cell structure and replication. Basic tissue types are covered in the following section, and the third section presents the microstructures of each of the major body systems. The highest -quality color light micrographs and electron micrograph images are accompanied by concise text and captions which explain the appearance, function, and clinical significance of each image. The accompanying website lets you view all the images from the atlas with a "virtual microscope", allowing you to view the image at a variety of pre-set magnifications. Utilizes "virtual microscope" function on the website, allowing you to see images first in low-powered and then in high powered magnification. Incorporates new information on histology of bone marrow, male reproductive system, respiratory system, pancreas, blood, cartilage, muscle types, staining methods, and more. Uses Color coding at the side of each page to make it easier to access information quickly and efficiently. Includes access to www.studentconsult.com, an interactive community center with a wealth of additional resources!