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Author : Eugene L. Parrott
Publisher : Burgess International Group Incorporated
ISBN 13 :
Total Pages : 348 pages
Book Rating : 4.3/5 (91 download)
Download or read book Experimental Pharmaceutics written by Eugene L. Parrott and published by Burgess International Group Incorporated. This book was released on 1977 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Abolghasem Jouyban
Publisher : CRC Press
ISBN 13 : 1439804885
Total Pages : 554 pages
Book Rating : 4.4/5 (398 download)
Download or read book Handbook of Solubility Data for Pharmaceuticals written by Abolghasem Jouyban and published by CRC Press. This book was released on 2009-08-26 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aqueous solubility is one of the major challenges in the early stages of drug discovery. One of the most common and effective methods for enhancing solubility is the addition of an organic solvent to the aqueous solution. Along with an introduction to cosolvency models, the Handbook of Solubility Data for Pharmaceuticals provides an extensive datab
Author : Walkiria S. Schlindwein
Publisher : John Wiley & Sons
ISBN 13 : 1118895215
Total Pages : 319 pages
Book Rating : 4.1/5 (188 download)
Download or read book Pharmaceutical Quality by Design written by Walkiria S. Schlindwein and published by John Wiley & Sons. This book was released on 2018-01-05 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to Quality by Design for pharmaceutical product development Pharmaceutical Quality by Design: A Practical Approach outlines a new and proven approach to pharmaceutical product development which is now being rolled out across the pharmaceutical industry internationally. Written by experts in the field, the text explores the QbD approach to product development. This innovative approach is based on the application of product and process understanding underpinned by a systematic methodology which can enable pharmaceutical companies to ensure that quality is built into the product. Familiarity with Quality by Design is essential for scientists working in the pharmaceutical industry. The authors take a practical approach and put the focus on the industrial aspects of the new QbD approach to pharmaceutical product development and manufacturing. The text covers quality risk management tools and analysis, applications of QbD to analytical methods, regulatory aspects, quality systems and knowledge management. In addition, the book explores the development and manufacture of drug substance and product, design of experiments, the role of excipients, multivariate analysis, and include several examples of applications of QbD in actual practice. This important resource: Covers the essential information about Quality by Design (QbD) that is at the heart of modern pharmaceutical development Puts the focus on the industrial aspects of the new QbD approach Includes several illustrative examples of applications of QbD in practice Offers advanced specialist topics that can be systematically applied to industry Pharmaceutical Quality by Design offers a guide to the principles and application of Quality by Design (QbD), the holistic approach to manufacturing that offers a complete understanding of the manufacturing processes involved, in order to yield consistent and high quality products.
Author : Reynir Eyjolfsson
Publisher : Academic Press
ISBN 13 : 012802187X
Total Pages : 68 pages
Book Rating : 4.1/5 (28 download)
Download or read book Design and Manufacture of Pharmaceutical Tablets written by Reynir Eyjolfsson and published by Academic Press. This book was released on 2014-10-09 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design and Manufacture of Pharmaceutical Tablets offers real world solutions and outcomes of formulation and processing challenges of pharmaceutical tablets. This book includes numerous practical examples related to actual formulations that have been validated and marketed and covers important data in the areas of stability, dissolution, bioavailibity and processing. It provides important background and theoretical information on design and manufacturing and includes a full section dedicated to design experimental methodology and statistics. In addition, this book offers a a general discussion of excipients used in proper tablet design along with practical examples related to excipients. Drug development scientists in industry and academia, as well as students in the pharmaceutical sciences will greatly benefit from the practical knowledge and case examples provided throughout this book. - Incorporates important mathematical models and computational applications - Includes unique content on central composite design and augmented simplex lattice - Provides background on important design principles with emphasis on quality-based design (QBD) of pharmaceutical dosage forms
Author : Tapan Kumar Chatterjee
Publisher : Pharmamed Press
ISBN 13 : 9789385433511
Total Pages : 306 pages
Book Rating : 4.4/5 (335 download)
Download or read book Rodents for Pharmacological Experiments written by Tapan Kumar Chatterjee and published by Pharmamed Press. This book was released on 2017-09-03 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book entitled "Rodents for Pharmacological Experiments" covers important pharmacological experiments on two kinds of rodents (mice and rats). The book describes wide range of contents and author has taken into consideration to enlighten all important topics related to pharmacological experiments with mice and rats. Section A of this book comprises about care, breeding, handling and nutrition etc. of laboratory mice and rats. Section B assembles most important methods for screening pharmacologically active substances using mice and rats. The methods described here are thoroughly and vividly written, thus providing readers with up-to-date information. This book also include two important topics like "Guidelines for care and use of animals in research" and "GLP for animal research." The book would obviously create interest to those researchers, who are in the quest of new pharmacologically active drugs. A variety of investigators in the field of Pharmacology, pharmaceutics, physiology, pharmacognosy, toxicology may find useful information and data for their research works from this book.
Author : Dr. Dharmendra Singh, Dr. Ravinesh Mishra, Dr. Chirag Goda, Dr Suhani Sinha, Kiran Singh
Publisher : Shashwat Publication
ISBN 13 : 9360875473
Total Pages : 222 pages
Book Rating : 4.3/5 (68 download)
Download or read book A Comprehensive Text Book for Fundamentals of Pharmaceutics written by Dr. Dharmendra Singh, Dr. Ravinesh Mishra, Dr. Chirag Goda, Dr Suhani Sinha, Kiran Singh and published by Shashwat Publication. This book was released on 2024-05-07 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Pharmaceutics" equips pharmacy students with the foundational knowledge outlined in the PCI syllabus (BP103T). Cornerstones of Pharmacy Explore the rich history of pharmacy in India, its evolution in education, industry, and career opportunities. Understand the role of pharmacopeias like IP, BP, and USP in drug standardization. It also coveres in depth knowledge of pharmaceutical calculations and have relevant information on monophasic liquids like syrups and biphasic systems like suspensions and emulsions, including their preparation and stability considerations. This book also covers suppositories, their types, benefits, and drawbacks, along with methods of preparation and evaluation. Understand pharmaceutical incompatibilities and learn about factors influencing drug penetration and the preparation methods for these formulations. All efforts have been made to present the subject in student friendly and easy to understand. This book is a genuine effort to clarify the basics of Pharmaceutics.
Author : Michael E. Aulton
Publisher : Elsevier Health Sciences
ISBN 13 : 0702042900
Total Pages : 909 pages
Book Rating : 4.7/5 (2 download)
Download or read book Aulton's Pharmaceutics written by Michael E. Aulton and published by Elsevier Health Sciences. This book was released on 2013 with total page 909 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Pharmaceutics is the art of pharmaceutical preparations. It encompasses design of drugs, their manufacture and the elimination of micro-organisms from the products. This book encompasses all of these areas."--Provided by publisher.
Author : Dr. Tejas Shivram Pachpute
Publisher : Academic Guru Publishing House
ISBN 13 : 8119843630
Total Pages : 216 pages
Book Rating : 4.1/5 (198 download)
Download or read book A Comprehensive Textbook Of Physical Pharmaceutics written by Dr. Tejas Shivram Pachpute and published by Academic Guru Publishing House. This book was released on 2024-02-16 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to offer students and professionals in the area of pharmacy and associated subjects a comprehensive grasp of physical principles that underlie the formulation of pharmaceuticals and the administration of drugs. Physical pharmaceutics is a subfield of the pharmaceutical sciences that focuses on the application of the fundamentals of physics and chemistry to the formulation, manufacture, and assessment of various dosage forms used in the pharmaceutical industry. It covers a broad variety of subjects, including solubility, diffusion, rheology, and interfacial phenomena, all of which are very important in the process of developing pharmaceutical products and ensuring their effectiveness. In this textbook, the goal is to address these subjects in a way that is both clear and organized. Also have presented the basic ideas and principles associated with the discipline, along with practical applications and examples from the field. A general introduction to the subject at hand is provided at the beginning of each chapter, which is then followed by in-depth examinations of pertinent theories, experimental methods, and applications in the actual world. Additionally, this book has included images, tables, and examples that have been worked out throughout the whole of the book to improve comprehension and make learning easier. This textbook will prove to be an invaluable resource for you, regardless of whether you are a student who is just starting in the field of pharmaceutical sciences or an experienced professional who is eager to enhance your knowledge. you will find it not only educational but also interesting, and ultimately helpful to your study of physical pharmaceutics as well as your practice in the field.
Author : Jiben Roy
Publisher : Elsevier
ISBN 13 : 1908818042
Total Pages : 449 pages
Book Rating : 4.9/5 (88 download)
Download or read book An Introduction to Pharmaceutical Sciences written by Jiben Roy and published by Elsevier. This book was released on 2011-07-25 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences.This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry.A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. - Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions - Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processes - Covers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries
Author : Sarwar Beg
Publisher :
ISBN 13 : 9789813343528
Total Pages : 0 pages
Book Rating : 4.3/5 (435 download)
Download or read book Design of Experiments for Pharmaceutical Product Development written by Sarwar Beg and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book volume provides complete and updated information on the applications of Design of Experiments (DoE) and related multivariate techniques at various stages of pharmaceutical product development. It discusses the applications of experimental designs that shall include oral, topical, transdermal, injectables preparations, and beyond for nanopharmaceutical product development, leading to dedicated case studies on various pharmaceutical experiments through illustrations, art-works, tables and figures. This book is a valuable guide for all academic and industrial researchers, pharmaceutical and biomedical scientists, undergraduate and postgraduate research scholars, pharmacists, biostatisticians, biotechnologists, formulations and process engineers, regulatory affairs and quality assurance personnel. .
Author : Sarwar Beg
Publisher : Academic Press
ISBN 13 : 0128163720
Total Pages : 450 pages
Book Rating : 4.1/5 (281 download)
Download or read book Pharmaceutical Quality by Design written by Sarwar Beg and published by Academic Press. This book was released on 2019-03-27 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Quality by Design: Principles and Applications discusses the Quality by Design (QbD) concept implemented by regulatory agencies to ensure the development of a consistent and high-quality pharmaceutical product that safely provides the maximum therapeutic benefit to patients. The book walks readers through the QbD framework by covering the fundamental principles of QbD, the current regulatory requirements, and the applications of QbD at various stages of pharmaceutical product development, including drug substance and excipient development, analytical development, formulation development, dissolution testing, manufacturing, stability studies, bioequivalence testing, risk and assessment, and clinical trials. Contributions from global leaders in QbD provide specific insight in its application in a diversity of pharmaceutical products, including nanopharmaceuticals, biopharmaceuticals, and vaccines. The inclusion of illustrations, practical examples, and case studies makes this book a useful reference guide to pharmaceutical scientists and researchers who are engaged in the formulation of various delivery systems and the analysis of pharmaceutical product development and drug manufacturing process. - Discusses vital QbD precepts and fundamental aspects of QbD implementation in the pharma, biopharma and biotechnology industries - Provides helpful illustrations, practical examples and research case studies to explain QbD concepts to readers - Includes contributions from global leaders and experts from academia, industry and regulatory agencies
Author : Françoise Nielloud
Publisher : CRC Press
ISBN 13 : 9780824703042
Total Pages : 660 pages
Book Rating : 4.7/5 (3 download)
Download or read book Pharmaceutical Emulsions and Suspensions written by Françoise Nielloud and published by CRC Press. This book was released on 2000-02-25 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analyzes construction of experiments, focusing on variables, models, matrices, and reproducibility. This timely reference systematically examines the basic concepts and theoretical issues, methodologies for experiment and measurement, and practical health applications of emulsions and dispersions-describing formulation problems and identifying potential carriers for the delivery or targeting of new drugs. Evaluates anionic, cationic, and nonionic surfactants as dispersing, emulsifying, foaming, penetrating, and wetting agents. Written by more than 20 international researchers, Pharmaceutical Emulsions and Suspensions discusses uses of macroemulsions and (submicron) microemulsions illuminates delivery devices such as microparticles, nanospheres, liposomes, and mixed micelles investigates the application of self-emulsifying drug delivery systems (SEDDS) introduces techniques for increasing drug solubility with nanosuspensions addresses stabilization, flocculation, and coagulation problems in pharmaceutical and cosmetic suspensions surveys drug delivery by way of dermatological, follicular, and ocular routes explains the pharmacodynamics, bioavailability, and pharmacokinetics in the drug formulation development process compares and contrasts monomeric and micellar adsorption at oil-water interfaces and more! Containing over 1800 references, tables, equations, drawings, and micrographs, Pharmaceutical Emulsions and Suspensions is an ideal resource for pharmacists; physical, surface, colloid, cosmetic, food, and agricultural chemists; and upper-level undergraduate and graduate students in these disciplines.
Author : Sarwar Beg
Publisher : Springer Nature
ISBN 13 : 9813347171
Total Pages : 99 pages
Book Rating : 4.8/5 (133 download)
Download or read book Design of Experiments for Pharmaceutical Product Development written by Sarwar Beg and published by Springer Nature. This book was released on 2021-01-12 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book volume provides complete and updated information on the applications of Design of Experiments (DoE) and related multivariate techniques at various stages of pharmaceutical product development. It discusses the applications of experimental designs that shall include oral, topical, transdermal, injectables preparations, and beyond for nanopharmaceutical product development, leading to dedicated case studies on various pharmaceutical experiments through illustrations, art-works, tables and figures. This book is a valuable guide for all academic and industrial researchers, pharmaceutical and biomedical scientists, undergraduate and postgraduate research scholars, pharmacists, biostatisticians, biotechnologists, formulations and process engineers, regulatory affairs and quality assurance personnel.
Author : D. C. Young
Publisher : John Wiley & Sons
ISBN 13 : 9780470451847
Total Pages : 344 pages
Book Rating : 4.4/5 (518 download)
Download or read book Computational Drug Design written by D. C. Young and published by John Wiley & Sons. This book was released on 2009-01-28 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helps you choose the right computational tools and techniques to meet your drug design goals Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts: Part One, The Drug Design Process, sets forth a variety of design processes suitable for a number of different drug development scenarios and drug targets. The author demonstrates how computational techniques are typically used during the design process, helping readers choose the best computational tools to meet their goals. Part Two, Computational Tools and Techniques, offers a series of chapters, each one dedicated to a single computational technique. Readers discover the strengths and weaknesses of each technique. Moreover, the book tabulates comparative accuracy studies, giving readers an unbiased comparison of all the available techniques. Part Three, Related Topics, addresses new, emerging, and complementary technologies, including bioinformatics, simulations at the cellular and organ level, synthesis route prediction, proteomics, and prodrug approaches. The book's accompanying CD-ROM, a special feature, offers graphics of the molecular structures and dynamic reactions discussed in the book as well as demos from computational drug design software companies. Computational Drug Design is ideal for both students and professionals in drug design, helping them choose and take full advantage of the best computational tools available. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Author : Chao Han
Publisher : John Wiley & Sons
ISBN 13 : 0470044918
Total Pages : 306 pages
Book Rating : 4.4/5 (7 download)
Download or read book Evaluation of Drug Candidates for Preclinical Development written by Chao Han and published by John Wiley & Sons. This book was released on 2010-01-19 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the "right" drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds. Now, Evaluation of Drug Candidates for Preclinical Development provides a complete view and understanding of why absorption-distribution-metabolism-excretion-toxicology (ADMET) plays a pivotal role in drug discovery and development. Encompassing the three major interrelated areas in which optimization and evaluation of drug developability is most critical—pharmacokinetics and drug metabolism, pharmaceutics, and safety assessment—this unique resource encourages integrated thinking in drug discovery. The contributors to this volume: Cover drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, stability, drug formulation, preclinical safety assessment, toxicology, and toxicokinetics Address developability issues that challenge pharma companies, moving beyond isolated experimental results Reveal connections between the key scientific areas that are critical for successful drug discovery and development Inspire forward-thinking strategies and decision-making processes in preclinical evaluation to maximize the potential of drug candidates to progress through development efficiently and meet the increasing demands of the marketplace Evaluation of Drug Candidates for Preclinical Development serves as an introductory reference for those new to the pharmaceutical industry and drug discovery in particular. It is especially well suited for scientists and management teams in small- to mid-sized pharmaceutical companies, as well as academic researchers and graduate students concerned with the practical aspects related to the evaluation of drug developability.
Author : N. Anthony Armstrong
Publisher : Taylor & Francis Group
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.3/5 (91 download)
Download or read book Understanding Experimental Design and Interpretation in Pharmaceutics written by N. Anthony Armstrong and published by Taylor & Francis Group. This book was released on 1990 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses experimental and optimization techniques in the context of pharmaceutical research, formulation and manufacture. Specific techniques are described, showing concepts, benefits and limitations. The book includes clinical and consumer trials from a spectrum of pharmaceutical sciences.
Author : Sarwar Beg
Publisher : Academic Press
ISBN 13 : 0128203331
Total Pages : 225 pages
Book Rating : 4.1/5 (282 download)
Download or read book Handbook of Analytical Quality by Design written by Sarwar Beg and published by Academic Press. This book was released on 2021-01-09 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Analytical Quality by Design addresses the steps involved in analytical method development and validation in an effort to avoid quality crises in later stages. The AQbD approach significantly enhances method performance and robustness which are crucial during inter-laboratory studies and also affect the analytical lifecycle of the developed method. Sections cover sample preparation problems and the usefulness of the QbD concept involving Quality Risk Management (QRM), Design of Experiments (DoE) and Multivariate (MVT) Statistical Approaches to solve by optimizing the developed method, along with validation for different techniques like HPLC, UPLC, UFLC, LC-MS and electrophoresis. This will be an ideal resource for graduate students and professionals working in the pharmaceutical industry, analytical chemistry, regulatory agencies, and those in related academic fields. - Concise language for easy understanding of the novel and holistic concept - Covers key aspects of analytical development and validation - Provides a robust, flexible, operable range for an analytical method with greater excellence and regulatory compliance
