A Combined Mri And Histology Atlas Of The Rhesus Monkey Brain In Stereotaxic Coordinates

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A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates

Author : Kadharbatcha S. Saleem
Publisher : Elsevier
ISBN 13 : 0080467776
Total Pages : 337 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates by : Kadharbatcha S. Saleem

Download or read book A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates written by Kadharbatcha S. Saleem and published by Elsevier. This book was released on 2006-11-21 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This book presents the detailed mapping of the architectonic areas in the horizontal plane of sections with reference to the MRI that has not been reported previously in macaque monkeys. In the second part of the atlas, the coronal plane is presented using the same technique. A third part shows the quick identification of several important cortical and subcortical areas (around 30 areas) in horizontal, coronal and sagittal MR images. This atlas is unlike anything else available as it includes and compares each section to imaging data. This is a significant progress, as the vast majority of research in the field now routinely work with fMRI images. · Provides the first combined MRI and Histology maps of the cortical and subcortical areas of any non-human primate species· Shows the first detailed delineations of the cortical and subcortical areas in both horizontal and coronal planes in the same animal using five different staining methods· Illustrates the entire dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographs matched with 47 detailed diagrams (Chapter 3) · Presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographs, and 76 corresponding drawings (Chapter 4)· Illustrates the selected cortical and subcortical areas in horizontal, coronal and sagittal MRI planes (Chapter 5)· Provides the sterotaxic grid derived from the in-vivo MR image· Likely to become a standard reference for anatomical, physiological, and functional imaging studies in primates (fMRI, PET and MEG)

A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates

Author : Kadharbatcha S. Saleem
Publisher : Academic Press
ISBN 13 : 0123850878
Total Pages : 402 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates by : Kadharbatcha S. Saleem

Download or read book A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates written by Kadharbatcha S. Saleem and published by Academic Press. This book was released on 2012-04-23 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates, Second Edition maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This edition of the atlas is unlike anything else available as it includes the detailed cyto- and chemoarchitectonic delineations of the brain areas in all three planes of sections (horizontal, coronal, and sagittal) that are derived from the same animal. This is a significant progress because in functional imaging studies, such as fMRI, both the horizontal and sagittal planes of sections are often the preferred planes given that multiple functionally active regions can be visualized simultaneously in a single horizontal or sagittal section. This combined MRI and histology atlas is designed to provide an easy-to-use reference for anatomical and physiological studies in macaque monkeys, and in functional-imaging studies in human and non-human primates using fMRI and PET. The first rhesus monkey brain atlas with horizontal, coronal, and sagittal planes of sections, derived from the same animal Shows the first detailed delineations of the cortical and subcortical areas in horizontal, coronal, and sagittal plane of sections in the same animal using different staining methods Horizonal series illustrates the dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographic sections matched with 47 detailed diagrams (Chapter 3) Coronal series presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographic sections, with 76 corresponding drawings (Chapter 4) Sagittal series shows the complete mediolateral extent of the left hemisphere in 30 sagittal MRI sections, with 30 corresponding drawings (Chapter 5). The sagittal series also illustrates the location of different fiber tracts in the white matter Individual variability - provides selected cortical and subcortical areas in three-dimensional MRI (horizontal, coronal, and sagittal MRI planes). For comparison, it also provides similar areas in coronal MRI section in six other monkeys. (Chapter 6) Vasculature - indicates the corresponding location of all major blood vessels in horizontal, coronal, and sagittal series of sections Provides updated information on the cortical and subcortical areas, such as architectonic areas and nomenclature, with references, in chapter 2 Provides the sterotaxic grid derived from the in-vivo MR image

The Rhesus Monkey Brain in Stereotaxic Coordinates

Author : George Paxinos
Publisher : Academic Press
ISBN 13 : 0128158530
Total Pages : 394 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Rhesus Monkey Brain in Stereotaxic Coordinates by : George Paxinos

Download or read book The Rhesus Monkey Brain in Stereotaxic Coordinates written by George Paxinos and published by Academic Press. This book was released on 2024-03-01 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paxinos and Petrides' The Rhesus Monkey Brain in Stereotaxic Coordinates is the most comprehensive and accurate atlas of the monkey brain currently available. The fourth edition of this classic book will be a complete revision, featuring many improvements and upgrades. Containing coronal diagrams and accompanying photographic plates spaced at 120 μm intervals, this atlas follows the same nomenclature and abbreviations conventions as the mouse, rat, chicken, and human brain atlases published under George Paxinos’ leadership. This atlas is suitable for researchers who work with both monkeys and humans. Constructed by the established leaders in neuroanatomical atlas development, the new edition will again be the indispensable resource for all scientists working on the primate nervous system. 141 completely revised coronal diagrams and accompanying colour photographic plates spaced at approximately 120 μm intervals 60 colour photographic coronal plates of SMI immunoreactivity with completely revised delineations Includes MR images at approximately the same levels as the coronal diagrams Follows the same nomenclature and abbreviations as the mouse, rat, chicken, marmoset and human brain atlases, with indications of correspondence to alternative macaque nomenclatures This atlas was used for the delineation and nomenclature of MRI-based macaque brain atlases for neuroimaging analyses, including the SARM

Cyto- and Myeloarchitectural Brain Atlas of the Ferret (Mustela putorius) in MRI Aided Stereotaxic Coordinates

Author : Susanne Radtke-Schuller
Publisher : Springer
ISBN 13 : 3319766260
Total Pages : 374 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Cyto- and Myeloarchitectural Brain Atlas of the Ferret (Mustela putorius) in MRI Aided Stereotaxic Coordinates by : Susanne Radtke-Schuller

Download or read book Cyto- and Myeloarchitectural Brain Atlas of the Ferret (Mustela putorius) in MRI Aided Stereotaxic Coordinates written by Susanne Radtke-Schuller and published by Springer. This book was released on 2018-11-04 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Description This stereotaxic atlas of the ferret brain provides detailed architectonic subdivisions of the cortical and subcortical areas in the ferret brain using high-quality histological material stained for cells and myelin together with in vivo magnetic resonance (MR) images of the same animal. The skull-related position of the ferret brain was established according to in vivo MRI and additional CT measurements of the skull. Functional denotations from published physiology and connectivity studies are mapped onto the atlas sections and onto the brain surface, together with the architectonic subdivisions. High-resolution MR images are provided at levels of the corresponding histology atlas plates with labels of the respective brain structures. The book is the first atlas of the ferret brain and the most detailed brain atlas of a carnivore available to date. It provides a common reference base to collect and compare data from any kind of research in the ferret brain. Key Features Provides the first ferret brain atlas with detailed delineations of cortical and subcortical areas in frontal plane. Provides the most detailed brain atlas of a carnivore to date. Presents a stereotaxic atlas coordinate system derived from high-quality histological material and in vivo magnetic resonance (MR) images of the same animal. Covers the ferret brain from forebrain to spinal cord at intervals of 0.6 mm on 58 anterior-posterior levels with 5 plates each. Presents cell (Nissl) stained frontal sections (plate 1) and myelin stained sections (plate 2) in a stereotaxic frame. Provides detailed delineations of brain structures and their denomination on a Nissl stained background on a separate plate (3). Compiles abbreviations on plate 4, a plate that also displays the low resolution MRI of the atlas brain with the outlines of the Nissl sections in overlay. Displays high-resolution MR images at intervals of 0.15 mm from another animal with labeled brain structures as plate 5 corresponding to the anterior-posterior level of each atlas plate. Provides detailed references used for delineation of brain areas. Target audience of the book: The book addresses researchers and students in neurosciences who are interested in brain anatomy in general (e.g., for translational purposes/comparative aspects), particularly those who study the ferret as important animal model of growing interest in neurosciences.

The Marmoset Brain in Stereotaxic Coordinates

Author : George Paxinos
Publisher : Academic Press
ISBN 13 : 9780124158184
Total Pages : 0 pages
Book Rating : 4.1/5 (581 download)

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Book Synopsis The Marmoset Brain in Stereotaxic Coordinates by : George Paxinos

Download or read book The Marmoset Brain in Stereotaxic Coordinates written by George Paxinos and published by Academic Press. This book was released on 2011-10-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Marmoset Brain in Stereotaxic Coordinates is the most comprehensive atlas of the brain of this animal available. The atlas is constructed in the style of The Rat Brain in Stereotaxic Coordinates, the most-cited book in neuroscience. It represents a collaboration between world leaders in neuroanatomy of the primate cortex and subcortex. It will be an indispensible tool for neuroanatomists, behavioral neuroscientists, and molecular biologists trying to understand the primate brain. ENDORSED BY SOCIETY FOR BRAIN MAPPING AND THERAPEUTICS (SBMT) - SBMT is a non-profit society organized for the purpose of encouraging basic and clinical scientists who are interested in areas of Brain Mapping, engineering, stem cell, nanotechnology, imaging and medical device to improve the diagnosis, treatment and rehabilitation of patients afflicted with neurological disorders. This society promotes the public welfare and improves patient care through the translation of new technologies/therapies into life saving diagnostic and therapeutic procedures. The Society is focused in breaking boundaries of science, technology, medicine, art and healthcare policy. For more information about how to become a member or participate in SBMT programs please visit: www.WorldBrainMapping.org

The 3-Dimensional Atlas of the Marmoset Brain

Author : Atsushi Iriki
Publisher : Springer
ISBN 13 : 4431566120
Total Pages : 388 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis The 3-Dimensional Atlas of the Marmoset Brain by : Atsushi Iriki

Download or read book The 3-Dimensional Atlas of the Marmoset Brain written by Atsushi Iriki and published by Springer. This book was released on 2018-12-12 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides accurate, comprehensive, and convenient reference for usages of the “freely rotatable three dimensional combined Nissl-stained and MRI digital data of the marmoset brain”. The key features of the original 3D digital data and of this atlas are: 1. The original digital datasets are freely rotatable in three dimensions, thus expected to be useful for any disciplines and anatomical interest, using any coordinate system, 2. Combined Nissl stained and MRI images are obtained from the same marmoset, to allow cross-modality matched references for multiple usages, 3. 86 Horizontal Series of Images with Neurosurgical Plane (based on the actual data), with more accuracy and resolution (Chapter 2) than the web-based digital images, 4. 32 Coronal Series of Images with Neurosurgical Plane (reproduced from the brain model) (Chapter 3), 5. 10 Parasagittal Series of Images with Neurosurgical Plane (reproduced from the brain model) (Chapter 4), 6. 3 Omnidirectionally Sliceable Planes (reproduced from the brain model) (Chapter 5), 7. In order to provide higher resolution structures to match systematic accuracy for supplementation of the digital data on the website, additional information are included. They are: 1) Nomenclature, 2) List of Brain Structures in Hierarchical Order, 3) Index of Abbreviations, together with 143 useful Bibliographic References list as of 2016, 8. Horsley-Clarke’s stereotaxic coordinates were adopted in the present atlas.

Atlas of Regional Anatomy of the Brain Using MRI

Author : Jean C. Tamraz
Publisher : Springer Science & Business Media
ISBN 13 : 3540306722
Total Pages : 344 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Atlas of Regional Anatomy of the Brain Using MRI by : Jean C. Tamraz

Download or read book Atlas of Regional Anatomy of the Brain Using MRI written by Jean C. Tamraz and published by Springer Science & Business Media. This book was released on 2006-02-08 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique review of the essential topographical anatomy of the brain from an MRI perspective, correlating high-quality anatomical plates with high-resolution MRI images. The book includes a historical review of brain mapping and an analysis of the essential reference planes used. It provides a detailed review of the sulcal and the gyral anatomy of the human cortex, guiding readers through an interpretation of the individual brain atlas provided by high-resolution MRI. The relationship between brain structure and function is approached in a topographical fashion with an analysis of the necessary imaging methodology and displayed anatomy. An extensive coronal atlas rounds off the book.

Neuraxial Therapeutics

Author : Tony Yaksh
Publisher : Springer Nature
ISBN 13 : 3031395581
Total Pages : 829 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Neuraxial Therapeutics by : Tony Yaksh

Download or read book Neuraxial Therapeutics written by Tony Yaksh and published by Springer Nature. This book was released on 2024-01-02 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive reference of the neuraxial route for the delivery of therapeutics. It reviews the historical evolution of this approach from its inception in the later 1800's to present day. This amply referenced text covers basic discussions of spinal anatomy, embryogenesis, neuraxial vascularity, cerebrospinal fluid flow dynamics and parenchymal molecule movement. The pharmacokinetic and pharmacodynamic properties of different intrathecal agents are explored in detail with particular reference to clinical correlates in pain and spasticity. Particular attention is paid to the issues relevant to preclinical models of intrathecal delivery and the assessment of spinal pathologies arising from acute and chronic intrathecal drug delivery. Chapters provide essential discussions of clinical aspects of patient care, including patient evaluation and screening, trialing and device management, troubleshooting problems and addressing complications, best practices, cost-effectiveness and future of the therapy. Clinicians and researchers who practice intrathecal therapy and study neuraxial mechanisms will find Neuraxial Therapeutics, to be an invaluable guide to this treatment modality.

Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464964114
Total Pages : 1751 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition by :

Download or read book Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 1751 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Applied, Analytical, and Imaging Sciences Research. The editors have built Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Applied, Analytical, and Imaging Sciences Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Neuroprosthetics

Author : Justin C. Sanchez
Publisher : CRC Press
ISBN 13 : 1466553243
Total Pages : 236 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Neuroprosthetics by : Justin C. Sanchez

Download or read book Neuroprosthetics written by Justin C. Sanchez and published by CRC Press. This book was released on 2018-09-03 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master the tools of design thinking using Neuroprosthetics: Principles and Applications. Developed from successfully tested material used in an undergraduate and graduate level course taught to biomedical engineering and neuroscience students, this book focuses on the use of direct neural sensing and stimulation as a therapeutic intervention for complex disorders of the brain. It covers the theory and applications behind neuroprosthetics and explores how neuroprosthetic design thinking can enhance value for users of a direct neural interface. The book explains the fundamentals of design thinking, introduces essential concepts from neuroscience and engineering illustrating the major components of neuroprosthetics, and presents practical applications. In addition to describing the approach of design thinking (based on facts about the user’s needs, desires, habits, attitudes, and experiences with neuroprosthetics), it also examines how effectively "human centered" neuroprosthetics can address people’s needs and interactions in their daily lives. Identifying concepts and features of devices that work well with users of a direct neural interface, this book: Outlines the signal sensing capabilities and trade-offs for common electrode designs, and determines the most appropriate electrode for any neuroprosthetic application Specifies neurosurgical techniques and how electronics should be tailored to capture neural signals Provides an understanding of the mechanisms of neural–electrode performance and information contained in neural signals Provides understanding of neural decoding in neuroprosthetic applications Describes the strategies that can be used to promote long-term therapeutic interventions for humans through the use of neuroprosthetics The first true primary text for undergraduate and graduate students in departments of neuroscience and bioengineering that covers the theory and applications behind this science, Neuroprosthetics: Principles and Applications provides the fundamental knowledge needed to understand how electrodes translate neural activity into signals that are useable by machines and enables readers to master the tools of design thinking and apply them to any neuroprosthetic application.

MRI Atlas of the Human Cerebellum

Author : Jeremy D. Schmahmann
Publisher : Academic Press
ISBN 13 : 0080574076
Total Pages : 187 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis MRI Atlas of the Human Cerebellum by : Jeremy D. Schmahmann

Download or read book MRI Atlas of the Human Cerebellum written by Jeremy D. Schmahmann and published by Academic Press. This book was released on 2000-08-16 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: The MRI Atlas of the Human Cerebellum constitutes the most complete, detailed work on the human cerebellum to date. This definitive work provides images in the three cardinal planes (sagittal, transverse, and coronal) at closely spaced intervals of 2 millimeters. The images are derived from MRI scans of one individual and from postmortem sections of another. It is the only such atlas set within the universally accepted framework of the Talairach stereotaxic system, derived from standard landmarks in the brain. The book includes a new nomenclature system (labeling system) which is easier to use, aids in understanding the organization of the cerebellum, and is consistent with earlier work on the anatomy of the cerebellum in animals and the development of the human cerebellum in infants.Recent studies have shown that the cerebellum is involved in much more than motor coordination alone: also in higher functions including memory, language, emotion, and attention, as well as sensory discrimination. This atlas facilitates this new era of study of the cerebellum, allowing investigators to identify cerebellar structures with precision. Everyone concerned with the anatomy, function, or dysfunction of the cerebellum should have a copy. Key Features* Provides the most comprehensive, detailed, and authoritative atlas of the human cerebellum* Contains 110 MRI images and 110 corresponding cryosection images* Includes a CD with all of the images and text from the book, supported by both PC and Macintosh computer platforms* Developed within the universally accepted framework of the Talairach stereotaxic system* Contains detailed myelin- and Nissl-stained histology of major nuclei* Presents a new, easy-to-use nomenclature system* Allows investigators to identify structures with precision and to address detailed structure-function correlations

The Auditory Cortex

Author : Jeffery A. Winer
Publisher : Springer Science & Business Media
ISBN 13 : 1441900748
Total Pages : 711 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis The Auditory Cortex by : Jeffery A. Winer

Download or read book The Auditory Cortex written by Jeffery A. Winer and published by Springer Science & Business Media. This book was released on 2010-12-02 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been substantial progress in understanding the contributions of the auditory forebrain to hearing, sound localization, communication, emotive behavior, and cognition. The Auditory Cortex covers the latest knowledge about the auditory forebrain, including the auditory cortex as well as the medial geniculate body in the thalamus. This book will cover all important aspects of the auditory forebrain organization and function, integrating the auditory thalamus and cortex into a smooth, coherent whole. Volume One covers basic auditory neuroscience. It complements The Auditory Cortex, Volume 2: Integrative Neuroscience, which takes a more applied/clinical perspective.

Neuroanatomy

Author : Adam Fisch
Publisher : Oxford University Press
ISBN 13 : 0199845794
Total Pages : 476 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Neuroanatomy by : Adam Fisch

Download or read book Neuroanatomy written by Adam Fisch and published by Oxford University Press. This book was released on 2012-03-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroanatomy: Draw It to Know It, Second Edition teaches neuroanatomy in a purely kinesthetic way. In using this book, the reader draws each neuroanatomical pathway and structure, and in the process, creates memorable and reproducible schematics for the various learning points in Neuroanatomy in a hands-on, enjoyable and highly effective manner. In addition to this unique method, Neuroanatomy: Draw it to Know It also provides a remarkable repository of reference materials, including numerous anatomic and radiographic brain images, muscle-testing photographs, and illustrations from many other classic texts, which enhance the learning experience.

Fundamental Neuropathology for Pathologists and Toxicologists

Author : Brad Bolon
Publisher : John Wiley & Sons
ISBN 13 : 0470227338
Total Pages : 661 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis Fundamental Neuropathology for Pathologists and Toxicologists by : Brad Bolon

Download or read book Fundamental Neuropathology for Pathologists and Toxicologists written by Brad Bolon and published by John Wiley & Sons. This book was released on 2011-10-04 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers pathologists, toxicologists, other medical professionals, and students an introduction to the discipline and techniques of neuropathology – including chemical and environmental, biological, medical, and regulatory details important for performing an analysis of toxicant-induced neurodiseases. In addition to a section on fundamentals, the book provides detailed coverage of current practices (bioassays, molecular analysis, and nervous system pathology) and practical aspects (data interpretation, regulatory considerations, and tips for preparing reports).

The Oxford Handbook of Voice Perception

Author : Sascha Frühholz
Publisher :
ISBN 13 : 0198743181
Total Pages : 977 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis The Oxford Handbook of Voice Perception by : Sascha Frühholz

Download or read book The Oxford Handbook of Voice Perception written by Sascha Frühholz and published by . This book was released on 2019 with total page 977 pages. Available in PDF, EPUB and Kindle. Book excerpt: Speech perception has been the focus of innumerable studies over the past decades. While our abilities to recognize individuals by their voice state plays a central role in our everyday social interactions, limited scientific attention has been devoted to the perceptual and cerebral mechanisms underlying nonverbal information processing in voices. The Oxford Handbook of Voice Perception takes a comprehensive look at this emerging field and presents a selection of current research in voice perception. The forty chapters summarise the most exciting research from across several disciplines covering acoustical, clinical, evolutionary, cognitive, and computational perspectives. In particular, this handbook offers an invaluable window into the development and evolution of the 'vocal brain', and considers in detail the voice processing abilities of non-human animals or human infants. By providing a full and unique perspective on the recent developments in this burgeoning area of study, this text is an important and interdisciplinary resource for students, researchers, and scientific journalists interested in voice perception.

Toxicologic Pathology

Author : Pritam S. Sahota
Publisher : CRC Press
ISBN 13 : 0429997469
Total Pages : 1224 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Toxicologic Pathology by : Pritam S. Sahota

Download or read book Toxicologic Pathology written by Pritam S. Sahota and published by CRC Press. This book was released on 2018-08-14 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the success of the first edition, this book is designed to provide practical and timely information for toxicologic pathologists working in pharmaceutical drug discovery and development. The majority of the book (Organ Systems) will provide detailed descriptions of histopathological lesions observed in drug development. In addition, it will provide information to assist the pathologist in making determinations of the origin of lesions as well as its relevance to human risk. Toxicologic Pathology: Nonclinical Safety Assessment, Second Edition includes 2 new concept chapters. The first of the new chapters address approaches for the evaluation of unique therapeutic modalities such as cell therapies, gene therapies, and gene expression knockdown therapies. While these still represent new developing therapeutic approaches, there has been significant experience with the therapeutic modalities in the last 5 years. The second new chapter addresses the nonclinical safety assessment of medical devices, a topic of increasing importance that was not addressed in a unique chapter in the first edition. The other concept chapters have been updated and cover important topics including the overview of drug development; principles of nonclinical safety assessment; an introduction to toxicologic pathology; techniques used in toxicologic pathology, clinical pathology, toxicokinetics, and drug development toxicogenomics; and spontaneous lesions. The 13 organ system chapters provide the specifics related to pathologic characteristics, differential diagnosis, and interpretation of toxic responses in each organ system. These chapters are specifically important for the bench pathologist but also for the toxicologist who interacts with pathologists and function as study toxicologists and project team representatives in the drug development arena.

The Rat Brain in Stereotaxic Coordinates

Author : George Paxinos
Publisher : Elsevier
ISBN 13 : 0080475159
Total Pages : 451 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Rat Brain in Stereotaxic Coordinates by : George Paxinos

Download or read book The Rat Brain in Stereotaxic Coordinates written by George Paxinos and published by Elsevier. This book was released on 2006-11-02 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: This completely revised edition of The Rat Brain in Stereotaxic Coordinates, the second most cited book in science, represents a dramatic update from the previous edition. Based on a single rat brain, this edition features an entirely new coronal set of tissue cut in regular 120 micron intervals with accompanying photographs and drawings of coronal, horizontal and sagittal sections of this new set. The use of the single brain allows for greater consistency between sections, while advances in histochemistry techniques provides increased refinement in the definition of brain areas, making this the most accurate and detailed stereotaxic rat atlas produced to date. The atlas will also include a CD-ROM featuring all of the graphics and text. Every lab working with the rat as an experimental animal model will want to use this book as their atlas of choice. This book is also available in a softcover spiral binding at the same price. Includes twice as many coronal sections, nissl plates, and sagittal plates as the previous edition Uses a single rat brain allowing for better consistency and better delineations in the line drawings of structures Provides improved stereotaxic coordinates at a higher level of detail Accompanying CD-ROM features graphics and text Now available as hardcover version and softcover version with a spiral binding at the same price