A Clinician’s Guide to HCV Treatment in the Primary Care Setting

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Author :
Publisher : Integritas Communications
ISBN 13 :
Total Pages : 31 pages
Book Rating : 4.:/5 (661 download)

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Book Synopsis A Clinician’s Guide to HCV Treatment in the Primary Care Setting by : Sherilyn Brinkley, MSN, CRNP

Download or read book A Clinician’s Guide to HCV Treatment in the Primary Care Setting written by Sherilyn Brinkley, MSN, CRNP and published by Integritas Communications. This book was released on 2022-07-19 with total page 31 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to treat and cure hepatitis C virus (HCV) infection is one of the greatest achievements of modern medicine. The simplified guidelines and the availability of highly effective and manageable direct-acting antiviral agents (DAA) regimens make it increasingly feasible to treat uncomplicated HCV in the primary care setting. This HCV eHealth SourceTM activity was developed to empower primary care clinicians, who are ideally positioned to lead frontline efforts to achieve the worldwide goal of eliminating HCV. Practices such as universal screening for HCV, the implementation of treatment regimens, and strategies for supporting, as well as monitoring, patients post-cure will be provided.

Hepatitis and Liver Cancer

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Author :
Publisher : National Academies Press
ISBN 13 : 0309153689
Total Pages : 252 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hepatitis and Liver Cancer by : Institute of Medicine

Download or read book Hepatitis and Liver Cancer written by Institute of Medicine and published by National Academies Press. This book was released on 2010-04-23 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

The Liver

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119436834
Total Pages : 3296 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-01-22 with total page 3296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Eliminating the Public Health Problem of Hepatitis B and C in the United States

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Author :
Publisher : National Academies Press
ISBN 13 : 0309438020
Total Pages : 187 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Eliminating the Public Health Problem of Hepatitis B and C in the United States by : National Academies of Sciences, Engineering, and Medicine

Download or read book Eliminating the Public Health Problem of Hepatitis B and C in the United States written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-06-01 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Guidelines on Hepatitis B and C Testing

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Author :
Publisher : World Health Organization
ISBN 13 : 9789241549981
Total Pages : 0 pages
Book Rating : 4.5/5 (499 download)

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Book Synopsis Guidelines on Hepatitis B and C Testing by : World Health Organization

Download or read book Guidelines on Hepatitis B and C Testing written by World Health Organization and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

A National Strategy for the Elimination of Hepatitis B and C

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Author :
Publisher : National Academies Press
ISBN 13 : 0309457297
Total Pages : 297 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis A National Strategy for the Elimination of Hepatitis B and C by : National Academies of Sciences, Engineering, and Medicine

Download or read book A National Strategy for the Elimination of Hepatitis B and C written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-30 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the second of two, builds off the conclusions of the first report and outlines a strategy for hepatitis reduction over time and specific actions to achieve them.

Guidelines for the Screening Care and Treatment of Persons with Chronic Hepatitis C Infection Updated Version April 2016

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Author :
Publisher : World Health Organization
ISBN 13 : 9241549610
Total Pages : 140 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Guidelines for the Screening Care and Treatment of Persons with Chronic Hepatitis C Infection Updated Version April 2016 by : World Health Organization

Download or read book Guidelines for the Screening Care and Treatment of Persons with Chronic Hepatitis C Infection Updated Version April 2016 written by World Health Organization and published by World Health Organization. This book was released on 2016-04-30 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of HCV therapeutics continues to evolve rapidly and since the World Health Organization (WHO) issued its first Guidelines for the screening care and treatment of persons with hepatitis C infection in 2014 several new medicines have been approved by at least one stringent regulatory authority. These medicines called direct-acting antivirals (DAAs) are transforming the treatment of HCV enabling regimens that can be administered orally are of shorter duration (as short as eight weeks) result in cure rates higher than 90% and are associated with fewer serious adverse events than the previous interfere on containing regimens. WHO is updating its hepatitis C treatment guidelines to provide recommendations for the use of these new medicines. The objectives of these WHO guidelines are to provide updated evidence-based recommendations for the treatment of persons with hepatitis C infection using where possible all DAA-only combinations. The guidelines also provide recommendations on the preferred regimens based on a patient?s HCV genotype and clinical history and assess the appropriateness of continued use of certain medicines. This document also includes existing recommendations on screening for HCV infection and care of persons infected with HCV that were first issued in 2014. The key audience for these guidelines are policy-makers in low- and middle-income countries who formulate country-specific treatment guidelines and who plan infectious disease treatment programmes and services in addition to those people responsible for delivering treatment. The guidelines are appropriate for all countries including high-income countries.

Comprehensive Handbook of Alcohol Related Pathology

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Author :
Publisher : Elsevier
ISBN 13 : 0080502318
Total Pages : 2556 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Comprehensive Handbook of Alcohol Related Pathology by : Victor R. Preedy

Download or read book Comprehensive Handbook of Alcohol Related Pathology written by Victor R. Preedy and published by Elsevier. This book was released on 2004-12-24 with total page 2556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive handbook is a "one-stop-shop" for all researchers involved in the field of alcohol-related harm at the whole body or cellular level. Over 100 chapters provide abundant information of a wide range of topics that extend from the evolutionary aspects of alcohol consumption and the prevalence of alcohol misuse to programmed cell death. Each chapter is highly illustrated with tables and figures making this a valuable reference for students, clinicians and researchers alike. *Over 100 chapters conveniently divided into 3 sections *Represents a 'one-stop-shop' of information with suitable indexing of the various pathways and processes *Each chapter is highly illustrated with tables as well as figures

Configurational Comparative Methods

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Author :
Publisher : SAGE
ISBN 13 : 1412942357
Total Pages : 241 pages
Book Rating : 4.4/5 (129 download)

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Book Synopsis Configurational Comparative Methods by : Benoît Rihoux

Download or read book Configurational Comparative Methods written by Benoît Rihoux and published by SAGE. This book was released on 2009 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new addition to the Applied Social Research Methods series is unrivalled, it is written by leaders in the growing field of rigorous, comparative techniques.

Chronic Illness Care

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Author :
Publisher : Springer
ISBN 13 : 3319718126
Total Pages : 561 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Chronic Illness Care by : Timothy P. Daaleman

Download or read book Chronic Illness Care written by Timothy P. Daaleman and published by Springer. This book was released on 2018-02-24 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive overview to chronic illness care, which is the coordinated, comprehensive, and sustained response to chronic diseases and conditions by a range of health care providers, formal and informal caregivers, healthcare systems, and community-based resources. Using an ecological framework, which looks at the interdependent influences between individuals and their larger environment, this unique text examines chronic illness care at multiple levels and includes sections on the individual influences on chronic illness, the role of family and social networks, and how chronic care is provided across the spectrum of health care settings; from home to clinic to the emergency department to hospital and residential care facilities. The book describes the organizational frameworks and strategies that are needed to provide quality care for chronically ill patients, including behavioral health, care management, transitions of care, and health information technology. The book also addresses the changing workforce needs in health care, and the fiscal models and policies that will be required to meet the needs of this population, with a focus on sustaining the ongoing transformation in health care. This book acts as a major reference for practitioners and students in medicine, nursing, social work, allied health, and behavioral medicine, as well as stakeholders in public health, health policy, and population health.

Sheehy's Manual of Emergency Care - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323710611
Total Pages : 578 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Sheehy's Manual of Emergency Care - E-Book by : Emergency Nurses Association

Download or read book Sheehy's Manual of Emergency Care - E-Book written by Emergency Nurses Association and published by Elsevier Health Sciences. This book was released on 2022-12-30 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: **American Journal of Nursing (AJN) Book of the Year Awards, 1st Place in Critical Care- Emergency Nursing, 2023** **Selected for Doody's Core Titles® 2024 in Emergency Care** Sheehy's Manual of Emergency Care, 8th Edition offers complete, up-to-date coverage of the essentials emergency nurses need to know. Each condition commonly seen in the emergency setting is thoroughly addressed, from signs and symptoms, to diagnosis, treatment, developmental considerations, patient education, and more. Updated material and easy-to-reference contents make this resource a must-have for current practice. - Quick-reference format is ideal for updating emergency nursing knowledge and improving patient care. - Detailed discussions for each condition include signs and symptoms, diagnosis/diagnostic testing, treatment/interventions, age/developmental considerations, and patient/family education/discharge instructions. - Authorship from the Emergency Nurses Association for more than 30 years ensures this book is a mainstay for best practices in emergency nursing. - Content presented in a bulleted format provides quick and easy access to vital information. - Practice points highlighted in special boxes offer quick reference to important content. - NEW! Restructured table of contents presents anatomically related medical and trauma chapters sequentially for quick reference. - NEW! Considerations for critical care in the ED. - NEW! Considerations for the transgender patient. - NEW! Section on human trafficking in the Interpersonal Violence and Abuse chapter. - NEW! Section on violent risk assessment in the Workplace Violence chapter. - NEW! Color photos insert visually highlights and clarifies key content. - EXPANDED! Substance Abuse and Addiction Emergencies chapter covers methamphetamines, bath salts, marijuana edibles, opioid abuse/prescription drug abuse, heroin/Narcan, and substance abuse disorder. - EXPANDED! Chapter on end-of-life includes information on palliative care considerations. - UPDATED! Infectious Diseases chapter addresses coronavirus 19 (COVID-19), Ebola, and vector-borne malaria.

Accelerating access to hepatitis C diagnostics and treatment

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Author :
Publisher : World Health Organization
ISBN 13 : 9240019006
Total Pages : 76 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Accelerating access to hepatitis C diagnostics and treatment by :

Download or read book Accelerating access to hepatitis C diagnostics and treatment written by and published by World Health Organization. This book was released on 2021-01-26 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO approved more hepatitis direct-acting antivirals (DAAs) for the treatment of infection with the hepatitis C virus (HCV) by 2020 which helped low- and middle-income countries increase the number of registered treatments, reduce prices of a full treatment under US$100 – update is as low as $60 for three months, and strive towards hepatitis C elimination. For the first time, this year’s report includes information on hepatitis C diagnostics. With a focus on selected countries with diverse HCV epidemics, the report provides updates on the various dimensions of access to HCV diagnostics and pharmaceutical products, including product pricing, the regulatory environment and patent status, which together shape the national hepatitis response in different settings. It highlights key areas for action by ministries of health and other government decision-makers, pharmaceutical manufacturers and technical partners. Globally, at the end of 2017, only 5 million – or 7% – of the 71 (62–79) million people chronically infected with HCV had cumulatively received treatment with DAAs. As countries continue to tackle the disease burden and service disruptions caused by the COVID-19 pandemic, it is critical to ensure that the recent momentum and gains in the response to hepatitis C are not lost. Against this backdrop, this report is a strong reminder to continue to invest in building resilient and sustainable health systems that are focused on universal health coverage.

Hepatitis C: Care and Treatment

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Author :
Publisher : Springer Nature
ISBN 13 : 3030677621
Total Pages : 219 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Hepatitis C: Care and Treatment by : Angelos Hatzakis

Download or read book Hepatitis C: Care and Treatment written by Angelos Hatzakis and published by Springer Nature. This book was released on 2021-05-10 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the reader with a detailed overview of the current state-of-the art approach of Hepatitis C management. It reviews the course of action in handling of chronic Hepatitis C patients with various HCV genotypes and treats special cases such as acute hepatitis, transplant and renal patients as well as people who inject drugs. The two volume work on Hepatitis C introduces to the topic by reviewing virology, diagnosis, epidemiology, prevention, management and elimination of HCV. The book provides a valuable source at full length for researchers and clinicians working on Hepatitis C.

Chronic Pain and HIV

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118777409
Total Pages : 192 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Chronic Pain and HIV by : Angela G. Giovanniello

Download or read book Chronic Pain and HIV written by Angela G. Giovanniello and published by John Wiley & Sons. This book was released on 2016-01-22 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients suffering from HIV/AIDS often experience chronic pain due to the many diseases and infections they pick up as a result of a weakened immune system. It interferes with their quality of life and physical functioning, impacts adherence to antiretroviral therapy and HIV primary care, and is associated with significant psychological/social distress and substance use disorders. Chronic Pain and HIV addresses all these complex issues that can influence pain care that can influence pain care for the patient with HIV and acts both as a primer and a comprehensive review to define the field of chronic pain management. Using a clear, clinical approach, key topics include the following: Musculoskeletal pain in individuals in HIV Headache in individuals with HIV Psychiatric comorbidities among individuals with HIV and chronic pain Potential benefit and harm of prescription opioids in HIV Pain at the end of life in individuals with AIDS Treatment of chronic pain syndromes in the HIV-infected person. Edited by an outstanding team with extensive experience in HIV/AIDS and pain/palliative care, every chapter is written by a world-famous expert in their field who provides a thorough review of the relevant literature, including the very latest in management guidelines from the leading international societies. Perfect for all those in primary care, as well as infectious disease specialists managing patients with HIV/AIDS, Chronic Pain and HIV provides sensible, straightforward clinical advice to ensure the best possible patient management.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016: Budget hearing: Department of Health and Human Services; Oversight hearing: The vital responsibilty of serving the nation's aging and disabled communities; National Institutes of Health; Department of Education; Department of Labor; Oversight hearing: Closing the achievement gap in higher education

Download Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016: Budget hearing: Department of Health and Human Services; Oversight hearing: The vital responsibilty of serving the nation's aging and disabled communities; National Institutes of Health; Department of Education; Department of Labor; Oversight hearing: Closing the achievement gap in higher education PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 594 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016: Budget hearing: Department of Health and Human Services; Oversight hearing: The vital responsibilty of serving the nation's aging and disabled communities; National Institutes of Health; Department of Education; Department of Labor; Oversight hearing: Closing the achievement gap in higher education by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016: Budget hearing: Department of Health and Human Services; Oversight hearing: The vital responsibilty of serving the nation's aging and disabled communities; National Institutes of Health; Department of Education; Department of Labor; Oversight hearing: Closing the achievement gap in higher education written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2015 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Infectious Diseases: A Clinical Approach

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Author :
Publisher : IP Communications
ISBN 13 : 0980458692
Total Pages : 769 pages
Book Rating : 4.9/5 (84 download)

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Book Synopsis Infectious Diseases: A Clinical Approach by : Allen Yung

Download or read book Infectious Diseases: A Clinical Approach written by Allen Yung and published by IP Communications. This book was released on 2010-06-01 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most textbooks on infectious diseases take a disease-specific and/or organ-specific approach. In this book a patient-centred approach is taken. The starting point is the patient’s presenting problem and its evolution. The focus is on clinical diagnosis and principles of management. The book comprises six parts. Part I, ‘General approach to infectious diseases’, establishes the patient-centred approach. Part II outlines presenting problems and syndromes, and Part III, infections of organ systems. These two sections highlight day-to-day problems faced by clinicians, differential diagnoses and management. Part IV covers specific infections, chosen for their importance or unique nature, and Part V deals with infectious problems in specific hosts and settings. Part VI outlines the principles of antimicrobial therapy and disease prevention through immunisation. The book concludes with a set of ‘golden rules of infectious diseases’. This is not a comprehensive infectious diseases textbook; it contains what the editors consider to be core knowledge and skills for the practising clinician. Infectious diseases in adults are the primary focus; paediatric infectious diseases are not covered in any detail. In this third edition All the original chapters have been thoroughly reviewed and updated. Three new chapters have been added: chapter 25, ‘Herpesvirus infections’, chapter 41, ‘Viral and rickettsial infections of particular relevance to Australia’, and chapter 43, ‘Infectious diseases in the South-East Asia region’. An Australasian character is evident, with the inclusion of five new authors from New Zealand and (where relevant and possible) the inclusion of data from New Zealand. The companion CD that was included in the second edition has not been retained. Senior medical students, graduates, and more experienced clinicians interested in the clinical skills of infectious diseases, will find this book refreshingly straightforward, easy to read, and rich with clinical pearls.

Adaptive Leadership: The Heifetz Collection (3 Items)

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Author :
Publisher : Harvard Business Review Press
ISBN 13 : 1625277784
Total Pages : 621 pages
Book Rating : 4.6/5 (252 download)

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Book Synopsis Adaptive Leadership: The Heifetz Collection (3 Items) by : Ronald A. Heifetz

Download or read book Adaptive Leadership: The Heifetz Collection (3 Items) written by Ronald A. Heifetz and published by Harvard Business Review Press. This book was released on 2014-09-23 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: In times of constant change, adaptive leadership is critical. This Harvard Business Review collection brings together the seminal ideas on how to adapt and thrive in challenging environments, from leading thinkers on the topic—most notably Ronald A. Heifetz of the Harvard Kennedy School and Cambridge Leadership Associates. The Heifetz Collection includes two classic books: Leadership on the Line, by Ron Heifetz and Marty Linsky, and The Practice of Adaptive Leadership, by Heifetz, Linsky, and Alexander Grashow. Also included is the popular Harvard Business Review article, “Leadership in a (Permanent) Crisis,” written by all three authors. Available together for the first time, this collection includes full digital editions of each work. Adaptive leadership is a practical framework for dealing with today’s mix of urgency, high stakes, and uncertainty. It has been used by individuals, organizations, businesses, and governments worldwide. In a world of challenging environments, adaptive leadership serves as a guide to distinguishing the essential from the expendable, beginning the meaningful process of adaption, and changing the status quo. Ronald A. Heifetz is a cofounder of the international leadership and consulting practice Cambridge Leadership Associates (CLA) and the founding director of the Center for Public Leadership at the Harvard Kennedy School. He is renowned worldwide for his innovative work on the practice and teaching of leadership. Marty Linsky is a cofounder of CLA and has taught at the Kennedy School for more than twenty-five years. Alexander Grashow is a Senior Advisor to CLA, having previously held the position of CEO.