Alternatives to Animal Testing

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Author :
Publisher : Springer
ISBN 13 : 9811324476
Total Pages : 136 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Alternatives to Animal Testing by : Hajime Kojima

Download or read book Alternatives to Animal Testing written by Hajime Kojima and published by Springer. This book was released on 2018-12-27 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.

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Author :
Publisher : Bib. Orton IICA / CATIE
ISBN 13 :
Total Pages : 16 pages
Book Rating : 4./5 ( download)

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Book Synopsis by :

Download or read book written by and published by Bib. Orton IICA / CATIE. This book was released on with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The History of Alternative Test Methods in Toxicology

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Author :
Publisher : Academic Press
ISBN 13 : 0128136987
Total Pages : 384 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The History of Alternative Test Methods in Toxicology by :

Download or read book The History of Alternative Test Methods in Toxicology written by and published by Academic Press. This book was released on 2018-10-20 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated, miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing, capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialized areas, such as inhalation toxicity studies. The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement, Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now-classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialised areas, such as inhalation toxicity studies.

Encyclopedia of Animal Rights and Animal Welfare [2 volumes]

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Publisher : Bloomsbury Publishing USA
ISBN 13 : 0313352569
Total Pages : 748 pages
Book Rating : 4.3/5 (133 download)

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Book Synopsis Encyclopedia of Animal Rights and Animal Welfare [2 volumes] by : Marc Bekoff

Download or read book Encyclopedia of Animal Rights and Animal Welfare [2 volumes] written by Marc Bekoff and published by Bloomsbury Publishing USA. This book was released on 2009-11-25 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: A landmark publishing achievement on the subject, the new edition of this acclaimed encyclopedia is expanded to two volumes, covering the full range of issues related to animal protection. Expanded to two volumes, the comprehensively updated new edition, Encyclopedia of Animal Rights and Animal Welfare: Second Edition is an extraordinary publishing event. It remains the only reference to cover the entire scope of animal rights and welfare from a global interdisciplinary perspective, with an international team of contributors assembled by Marc Bekoff covering animal treatment issues in the United States, China, India, Kenya, Australia, and many other nations. With a focused emphasis on fairness and justice for animals evident on every page, Encyclopedia of Animal Rights and Animal Welfare: Second Edition offers clear explanations of hot-button topics like puppy mills, endangered species in zoos, no-kill shelters, dog fighting, factory farming and disease, veganism, conservation ethics, wildlife contraception, and more. The encyclopedia also explores a range of religious, ethical, and philosophical views on using animals, as well as the latest research on animal cognition and sentience. The work helps readers understand the different viewpoints of animal welfare advocates who want to improve conditions for animals and animal rights activists who don't want animals used at all.

The Welfare of Animals Used in Research

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Publisher : John Wiley & Sons
ISBN 13 : 1119967074
Total Pages : 294 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis The Welfare of Animals Used in Research by : Robert C. Hubrecht

Download or read book The Welfare of Animals Used in Research written by Robert C. Hubrecht and published by John Wiley & Sons. This book was released on 2014-05-05 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Welfare of Animals used in Research: Practice and Ethics gives a complete and balanced overview of the issues surrounding the use of animals in scientific research. The focus of the book is on the animal welfare implications and ethics of animals in research. It covers the topics with sufficient depth to show a real understanding of varied and complex subjects, but conveys the information in a beautifully reader-friendly manner. Key features: Provides those who are not working in the field with a reasonable understanding as to why and how animals are used in research. Gives an introduction to the ethical issues involved in using animals, and explains how these are addressed in practice. Details the advances in animal welfare and the use and development of the 3Rs principles, and how these have become fundamental to the everyday use and regulation of animals used in research. The focus is on principles making it suitable for an international audience. This book is a useful introduction to the issues involved in laboratory animal welfare for those who intend to work in research involving animals. It is also useful to prospective animal care staff and animal welfare scientists, and to those involved in ethical review. It will help inform debate amongst those who are not involved in experimentation but who are interested in the issues. Published as a part of the prestigious Wiley-Blackwell – UFAW Animal Welfare series. UFAW, founded 1926, is an internationally recognised, independent, scientific and educational animal welfare charity. For full details of all titles available in the series, please visit the UFAW Animal Welfare series website.

Teaching Science Online

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Publisher : Taylor & Francis
ISBN 13 : 1000979512
Total Pages : 240 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Teaching Science Online by : Dietmar Kennepohl

Download or read book Teaching Science Online written by Dietmar Kennepohl and published by Taylor & Francis. This book was released on 2023-07-03 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the increasing focus on science education, growing attention is being paid to how science is taught. Educators in science and science-related disciplines are recognizing that distance delivery opens up new opportunities for delivering information, providing interactivity, collaborative opportunities and feedback, as well as for increasing access for students. This book presents the guidance of expert science educators from the US and from around the globe. They describe key concepts, delivery modes and emerging technologies, and offer models of practice. The book places particular emphasis on experimentation, lab and field work as they are fundamentally part of the education in most scientific disciplines. Chapters include:* Discipline methodology and teaching strategies in the specific areas of physics, biology, chemistry and earth sciences.* An overview of the important and appropriate learning technologies (ICTs) for each major science.* Best practices for establishing and maintaining a successful course online.* Insights and tips for handling practical components like laboratories and field work.* Coverage of breaking topics, including MOOCs, learning analytics, open educational resources and m-learning.* Strategies for engaging your students online.

Environmental Health Perspectives

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Publisher :
ISBN 13 :
Total Pages : 458 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Environmental Health Perspectives by :

Download or read book Environmental Health Perspectives written by and published by . This book was released on 1996 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Experimentation: Working Towards a Paradigm Change

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Publisher : BRILL
ISBN 13 : 9004391193
Total Pages : 749 pages
Book Rating : 4.0/5 (43 download)

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Book Synopsis Animal Experimentation: Working Towards a Paradigm Change by : Kathrin Herrmann

Download or read book Animal Experimentation: Working Towards a Paradigm Change written by Kathrin Herrmann and published by BRILL. This book was released on 2019-04-30 with total page 749 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

Animal Welfare Information Center Newsletter

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Publisher :
ISBN 13 :
Total Pages : 178 pages
Book Rating : 4.U/5 (183 download)

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Book Synopsis Animal Welfare Information Center Newsletter by :

Download or read book Animal Welfare Information Center Newsletter written by and published by . This book was released on 1990 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Models for the Study of Human Disease

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Publisher : Academic Press
ISBN 13 : 0124159125
Total Pages : 1109 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Animal Models for the Study of Human Disease by : P. Michael Conn

Download or read book Animal Models for the Study of Human Disease written by P. Michael Conn and published by Academic Press. This book was released on 2013-05-29 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. - Organized by disease orientation for ease of searchability - Provides information on locating resources, animal alternatives and animal ethics - Covers a broad range of animal models used in research for human disease

Animal Models for the Study of Human Disease

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Author :
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128071923
Total Pages : 28 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Animal Models for the Study of Human Disease by : Judith Axler Turner

Download or read book Animal Models for the Study of Human Disease written by Judith Axler Turner and published by Elsevier Inc. Chapters. This book was released on 2013-05-29 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifying and selecting the most appropriate animal model is a challenge, but the U.S. Federal Government’s National Institutes of Health, has supported several efforts to make the job of finding disease models easier. These efforts began with support for databases about specific species, and have graduated to support for discipline-specific studies and cross-species resources. This article tracks LAMHDI, the initiative to Link Animal Models to Human DIsease (www.lamhdi.org), which brings together data about five species: flies, mice, rats, yeast, and zebrafish, and allows scientists to search across these data, principally by disease and gene. This chapter explains how LAMHDI was conceived, and where LAMHDI hopes to go in moving into phenotypical as well as genotypical data through networks and visualization.

Directory of Resources on Alternatives and Animal Use in the Life Sciences

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Author :
Publisher :
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Directory of Resources on Alternatives and Animal Use in the Life Sciences by :

Download or read book Directory of Resources on Alternatives and Animal Use in the Life Sciences written by and published by . This book was released on 1998 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alternative Methodologies for the Safety Evaluation of Chemicals in the Cosmetic Industry

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Author :
Publisher : CRC Press
ISBN 13 : 1000693708
Total Pages : 272 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Alternative Methodologies for the Safety Evaluation of Chemicals in the Cosmetic Industry by : Nicola Loprieno

Download or read book Alternative Methodologies for the Safety Evaluation of Chemicals in the Cosmetic Industry written by Nicola Loprieno and published by CRC Press. This book was released on 2019-08-15 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1995: Alternative Methodologies for the Safety Evaluation of Chemicals in the Cosmetic Industry presents a categorization and collection of information available for the evaluation of safety using in vitro techniques. It offers a comprehensive and complete look at the entire field. In doing so, the author provides the foundation for the next phase of significant growth for this discipline.

The Laboratory Mouse

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Publisher : Academic Press
ISBN 13 : 0123820081
Total Pages : 869 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis The Laboratory Mouse by : Hans Hedrich

Download or read book The Laboratory Mouse written by Hans Hedrich and published by Academic Press. This book was released on 2012-07-16 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse"--Provided by publisher.

Handbook of Laboratory Animal Science

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Publisher : CRC Press
ISBN 13 : 0429801602
Total Pages : 1013 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Handbook of Laboratory Animal Science by : Jann Hau

Download or read book Handbook of Laboratory Animal Science written by Jann Hau and published by CRC Press. This book was released on 2021-05-17 with total page 1013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide. It covers the essential principles and practices of Laboratory Animal Science as well as selected animal models in scientific disciplines where much progress has been made in recent years. Each individual chapter focuses on an important subdiscipline of laboratory animal science, and the chapters can be read and used as stand-alone texts, with only limited necessity to consult other chapters for information. With new contributors at the forefront of their fields, the book reflects the scientific and technological advances of the past decade. It also responds to advances in our understanding of animal behavior, emphasizing the importance of implementing the three Rs: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort. This fourth edition will be useful all over the world as a textbook for laboratory animal science courses for postgraduate and undergraduate students and as a handbook for scientists who work with animals in their research, for university veterinarians, and for other specialists in laboratory animal science.

Practical Field Ecology

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Publisher : John Wiley & Sons
ISBN 13 : 0470976705
Total Pages : 308 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Practical Field Ecology by : C. Philip Wheater

Download or read book Practical Field Ecology written by C. Philip Wheater and published by John Wiley & Sons. This book was released on 2011-04-12 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces experimental design and data analysis / interpretation as well as field monitoring skills for both plants and animals. Clearly structured throughout and written in a student-friendly manner, the main emphasis of the book concentrates on the techniques required to design a field based ecological survey and shows how to execute an appropriate sampling regime. The book evaluates appropriate methods, including the problems associated with various techniques and their inherent flaws (e.g. low sample sizes, large amount of field or laboratory work, high cost etc). This provides a resource base outlining details from the planning stage, into the field, guiding through sampling and finally through organism identification in the laboratory and computer based data analysis and interpretation. The text is divided into six distinct chapters. The first chapter covers planning, including health and safety together with information on a variety of statistical techniques for examining and analysing data. Following a chapter dealing with site characterisation and general aspects of species identification, subsequent chapters describe the techniques used to survey and census particular groups of organisms. The final chapter covers interpreting and presenting data and writing up the research. The emphasis here is on appropriate wording of interpretation and structure and content of the report.

Reflections on Bioethics

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Publisher : BoD – Books on Demand
ISBN 13 : 178923218X
Total Pages : 200 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Reflections on Bioethics by : Jose Antonio Morales-Gonzalez

Download or read book Reflections on Bioethics written by Jose Antonio Morales-Gonzalez and published by BoD – Books on Demand. This book was released on 2018-06-27 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Reflections on Bioethics is an effort that brings together works grouped into five sections: "Bioethics and Health", "Bioethics and Education", "Bioethics and Technology", "Bioethics in the Use of Experimental Animals",and "Selected Topics of Bioethics". In each of these sections, the fundamental concepts of bioethics and their relationship with each of these branches of knowledge are covered. The purpose is to give the reader a specific document of topics, it is not intended to be a treaty because the study of any of the five sections is very broad. However, this is an effort that manages to combine in interdisciplinary subjects that are fundamental for professionals of all fields of knowledge.