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Zinc Metabolism In Man
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Book Synopsis Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc by : Institute of Medicine
Download or read book Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc written by Institute of Medicine and published by National Academies Press. This book was released on 2002-07-19 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.
Book Synopsis Zinc in Human Biology by : Colin F. Mills
Download or read book Zinc in Human Biology written by Colin F. Mills and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume is one of a series concerned with topics considered to be of growing interest to those whose ultimate aim is the understanding of the nutrition of man. Volumes on Sweetness, Calcium in Human Biology and Sucrose: Nutritional and Safety Aspects, have already been published, and another, on Dietary Starches and Sugars in Man: A Comparison, is in preparation. Written for workers in the nutritional and allied sciences rather than for the specialist, they aim to fill the gap between the textbook on the one hand and the many publications addressed to the expert on the other. The target readership spans medicine, nutrition and the biological sciences generally and includes those in the food, chemical and allied industries who need to take account of advances in these fields relevant to their products. Funded by industry but with an independent status, the Inter national Life Sciences Institute (ILSI) is a non-profit organization founded to deal objectively with the numerous health and safety issues that today concern industry internationally. ILSI sponsors scientific research, organizes conferences and publishes monographs relative to these problems. London Ian Macdonald March 1988 Series Editor Preface This volume has been prepared at a time when interest in both the biological roles of zinc and its nutritional significance is growing rapidly.
Book Synopsis Zinc Metabolism in Man by : Kevin Edward Mohr
Download or read book Zinc Metabolism in Man written by Kevin Edward Mohr and published by . This book was released on 1977 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Assessment of Zinc Metabolism in Humans Using Stable Zinc Isotope Techniques by : International Atomic Energy Agency
Download or read book Assessment of Zinc Metabolism in Humans Using Stable Zinc Isotope Techniques written by International Atomic Energy Agency and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Chronic Exposure to 3% CO2 on Zinc Metabolism in Man by : Carl Lee Giannetta
Download or read book Effects of Chronic Exposure to 3% CO2 on Zinc Metabolism in Man written by Carl Lee Giannetta and published by . This book was released on 1973 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Assessment of Zinc Metabolism in Humans Using Stable Zinc Isotope Techniques by : International Atomic Energy Agency
Download or read book Assessment of Zinc Metabolism in Humans Using Stable Zinc Isotope Techniques written by International Atomic Energy Agency and published by . This book was released on 2019-02-25 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assessment of Zinc Metabolism in Humans Using Stable Zinc Isotope Techniques
Book Synopsis Clinical Applications of Recent Advances in Zinc Metabolism by : Ananda Shiva Prasad
Download or read book Clinical Applications of Recent Advances in Zinc Metabolism written by Ananda Shiva Prasad and published by . This book was released on 1982 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Twelve papers from a 1981 clinical workshop address a number of issues in zinc (Zn) research that are ofparticular relevance to clinicians and health care professionals. Emphasis is placed on areas of fundamental Znresearch that have the greatest clinical importance, and on new findings that are directly related to human nutritional health. The papers cover: historical aspects of Zn in human nutrition; the role of Zn at particular human developmental stages (prenatal; maternal nutritional status and pregnancy outcome), and in total parenteral nutrition; clinical disorders of Zn deficiency, and its diagnosis by hair and plasma analysis; the presence and distribution of Zn in milk, and an assessment of current knowledge on the role of Zn in normal cellular function. (wz).
Book Synopsis Zinc Metabolism by : Ananda Shiva Prasad
Download or read book Zinc Metabolism written by Ananda Shiva Prasad and published by . This book was released on 1966 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Kinetic Studies of Zinc Metabolism in Man and Animals by : Nicola Mary Lowe
Download or read book Kinetic Studies of Zinc Metabolism in Man and Animals written by Nicola Mary Lowe and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effect of a Low Zinc Intake on Zinc Homeostasis and Immune Function in Adult Men by : Kathryn Pinna
Download or read book Effect of a Low Zinc Intake on Zinc Homeostasis and Immune Function in Adult Men written by Kathryn Pinna and published by . This book was released on 1999 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Diet and Health by : National Research Council
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Book Synopsis Zinc in Human Nutrition by : Ananda Shiva Prasad
Download or read book Zinc in Human Nutrition written by Ananda Shiva Prasad and published by . This book was released on 1979 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Zinc and Human Health by : Sara H. Wuehler
Download or read book Zinc and Human Health written by Sara H. Wuehler and published by Initiative micronutriments = Micronutrient Initiative. This book was released on 2000 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zinc and Human Health: Results of Recent Trials and Implications for Program Interventions and Research
Book Synopsis Zinc Metabolism and Its Effect on Man with Particular Emphasis on Bone and Dental Tissues by : Gaber Moustafa K. Yakot
Download or read book Zinc Metabolism and Its Effect on Man with Particular Emphasis on Bone and Dental Tissues written by Gaber Moustafa K. Yakot and published by . This book was released on 1982 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nutrition and Traumatic Brain Injury by : Institute of Medicine
Download or read book Nutrition and Traumatic Brain Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.
Book Synopsis Studies on Zinc Metabolism and Metallothionein in Man and Animals by : Michael Anthony Sweeney
Download or read book Studies on Zinc Metabolism and Metallothionein in Man and Animals written by Michael Anthony Sweeney and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Whole Body, Cellular, and Molecular Changes in Healthy Men Consuming Low, Moderate, Or Supplemental Zinc Intakes by : Sarah J. Zyba
Download or read book Whole Body, Cellular, and Molecular Changes in Healthy Men Consuming Low, Moderate, Or Supplemental Zinc Intakes written by Sarah J. Zyba and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Zinc deficiency is a leading global health concern and is a contributing factor to stunting and impaired immune function. The World Health Organization estimates that 1.4% of deaths worldwide can be attributed to zinc deficiency. However, due to the fact that zinc is required for many metabolic pathways in the human body and symptoms of zinc deficiency are non-specific, scientists have struggled to identify a sensitive and specific biomarker for zinc. To evaluate the effect changes in dietary zinc have on healthy individuals, a zinc depletion/ repletion study was conducted. In this study, eighteen healthy men, age 18-39, were provided a moderately low zinc (6 mg/day) diet with added phytic acid (1.5 g/d) for two weeks to facilitate zinc deficiency followed by a moderate zinc (10 mg/day) diet for four weeks. They then consumed an ad libitum diet while taking a 25mg zinc supplement for three weeks. The study diet was based on a traditional high-carbohydrate, low-animal source protein Bangladeshi diet. To determine what effect changing dietary zinc has on zinc absorption and whole-body zinc metabolism, fractional zinc absorption (FZA) and the size of the exchangeable zinc pool (EZP) were measured using a dual-tracer isotope method. Total absorbed zinc (TAZ) was then calculated from FZA. Blood samples were also collected throughout the study to look at cellular markers of zinc status and changes in the proteome. The results of this study are presented in three chapters. The first chapter evaluated the impact an increase of 4 mg dietary zinc per day had on the absorption and size of the exchangeable zinc pool of the participants. FZA decreased by 6.4% with the moderate zinc diet compared to the low-zinc diet, but TAZ increased by 0.7 mg with the moderate zinc diet. EZP did not change with any changes to the diet. These results indicate that neither an increase in 4 mg dietary zinc per day for four weeks, nor a 25 mg zinc supplement for three weeks was sufficient to affect the EZP of adult men. However, an increase in 4mg zinc per day increased absorbed zinc by 0.7 mg.The second chapter evaluated changes in cellular zinc markers including white blood cell (WBC), and red blood cell (RBC) zinc concentrations, WBC zinc transporters and metallothionein gene expression, in vitro WBC 65Zn uptake, and WBC DNA damage in the participants during the zinc depletion/repletion study. mRNA expression of zinc transporters, including ZIP1, ZIP4, ZIP8, ZNT1, and ZNT7, and a metallothionein gene (MT2a) was examined in isolated WBCs. ZNT1 and ZNT7 gene expression increased while ZIP4 gene expression decreased during the low zinc phase, although total plasma and WBC zinc concentrations did not change nor did in vitro WBC 65Zn uptake. Total DNA strand breaks and DNA strand breaks due to oxidative damage increased with a low zinc diet. Total DNA strand breaks then returned to baseline levels when the dietary zinc was increased to 10 mg/d during the moderate zinc phase, but strand breaks due to oxidative damage did not. These results show that a two-week, low zinc intake alters gene expression of ZNT1, ZNT7 and ZIP4 in WBCs, without any change in plasma zinc concentration. Also, DNA integrity is sensitive to changes in dietary zinc as small as 4 mg/d. Both WBC zinc transporter gene expression and DNA integrity may be useful to evaluate zinc deficiency and the effectiveness of zinc interventions even when plasma zinc concentrations remain unchanged.The fourth chapter evaluated changes in plasma proteins when healthy men consume a low zinc diet followed by moderate dietary zinc and when they consumed a zinc supplement. Of 1129 proteins that were measured, 19 proteins responded to changes in dietary zinc. These proteins either increased or decreased significantly with a 6 mg + phytate diet and then returned to the baseline after the participants consumed a 10 mg zinc diet for four weeks. The proteins that responded to the dietary zinc changes generally belonged to two metabolic categories: inflammation and apoptosis. The 6 mg zinc diet led to a pro-inflammatory and pro-apoptotic state that recovered when participants were fed a 10 mg zinc diet for four weeks. Forty-one proteins changed between baseline and the 3-week supplementation period with 25 mg zinc. These proteins varied in function and did no show a clear effect of zinc supplementation on a specific aspect of the proteome. Consuming a 6 mg zinc diet with added phytate induced a pro-inflammatory pro-apoptotic state in healthy men. Increasing dietary zinc to 10 mg /d and removing phytate permitted the plasma proteins to return to the baseline levels. Together these results show that even small changes in dietary zinc can have a significant impact on cellular function and zinc metabolism as well as the plasma proteome even when plasma zinc concentration is not affected. Some of the cellular and proteomic markers measured here may provide a sensitive and specific marker for diagnosing zinc deficiency or evaluating effectiveness of zinc dietary interventions.
