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Ww Domain Proteins In Signaling Cancer Growth Neural Diseases And Metabolic Disorders
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Book Synopsis WW Domain Proteins in Signaling, Cancer Growth, Neural Diseases, and Metabolic Disorders by : Nan-Shan Chang
Download or read book WW Domain Proteins in Signaling, Cancer Growth, Neural Diseases, and Metabolic Disorders written by Nan-Shan Chang and published by Frontiers Media SA. This book was released on 2019-11-18 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Signal Transduction in Cancer by : David A. Frank
Download or read book Signal Transduction in Cancer written by David A. Frank and published by Springer Science & Business Media. This book was released on 2002-12-31 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Glycome Informatics by : Kiyoko F. Aoki-Kinoshita
Download or read book Glycome Informatics written by Kiyoko F. Aoki-Kinoshita and published by CRC Press. This book was released on 2009-11-19 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Focused, State-of-the-Art Overview of This Evolving FieldPresents Various Techniques for GlycoinformaticsThe development and use of informatics tools and databases for glycobiology and glycomics research have increased considerably in recent years. In addition to accumulating well-structured glyco-related data, researchers have now developed semi
Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Book Synopsis Leucine-Rich Repeat Kinase 2 (LRRK2) by : Hardy J. Rideout
Download or read book Leucine-Rich Repeat Kinase 2 (LRRK2) written by Hardy J. Rideout and published by Springer. This book was released on 2017-03-28 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Essentials of Glycobiology by : Ajit Varki
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Book Synopsis Autophagy in Health and Disease by : Roberta A. Gottlieb
Download or read book Autophagy in Health and Disease written by Roberta A. Gottlieb and published by Academic Press. This book was released on 2012-12-31 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information. Discusses current understanding of the roles of autophagy in health and disease Covers the background of autophagy, the development of tools and therapeutics to measure and modulate autophagy, and autophagy in tissues and disease processes
Book Synopsis Emerging Cellular Stress Sensors in Neurological Disorders: Closing in on the Nucleolus and the Primary Cilium by : Rosanna Parlato
Download or read book Emerging Cellular Stress Sensors in Neurological Disorders: Closing in on the Nucleolus and the Primary Cilium written by Rosanna Parlato and published by Frontiers Media SA. This book was released on 2020-05-21 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Mechanism of Alzheimer's Disease by : Ian Macreadie
Download or read book Molecular Mechanism of Alzheimer's Disease written by Ian Macreadie and published by MDPI. This book was released on 2019-10-25 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer’s disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue.
Book Synopsis Regulation of Ubiquitination and Sumoylation Signaling in Disease by : Zhenghong Lin
Download or read book Regulation of Ubiquitination and Sumoylation Signaling in Disease written by Zhenghong Lin and published by Frontiers Media SA. This book was released on 2022-08-05 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Epidemiology of Brain and Spinal Tumors by : Jahangir Moini
Download or read book Epidemiology of Brain and Spinal Tumors written by Jahangir Moini and published by Academic Press. This book was released on 2021-04-09 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment
Book Synopsis The Molecular Basis of Programmed Cell Death and Neuroinflammation in Neurodegenerative Diseases by : Ramkumar Mathur
Download or read book The Molecular Basis of Programmed Cell Death and Neuroinflammation in Neurodegenerative Diseases written by Ramkumar Mathur and published by Frontiers Media SA. This book was released on 2024-01-25 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Age-related neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuroinflammation as well as neuronal degeneration. Apoptosis, necrosis, and autophagy are all types of programmed cell death that are morphologically distinct from one another. Over the last decade, extensive research has been conducted on necroptosis, resulting in a better understanding of its molecular underpinnings and role in neurodegenerative diseases. A later study investigates the processes of apoptosis and necroptosis, as well as their roles in the activation of inflammatory immune responses. Although there is a distinct mode of cell death with distinct morphological characteristics, its identification and implications in neurological diseases are still unknown. Interestingly, emerging evidence has established a direct link between epigenetic and posttranslational modifications and neurodegenerative disease. Using epigenetic and proteomic methods, researchers uncovered genes and proteins that may play a function in the area of neuroinflammation, a role that has hitherto been overlooked. New pharmacological targets and therapeutic options for neurodegenerative diseases are being investigated in order to gain a better understanding of the disease's origins and progression by using neuronal death and neuroinflammation models that are associated with epigenetic changes.
Book Synopsis Brain Neurosecretory Cytokines by : Armen A. Galoyan
Download or read book Brain Neurosecretory Cytokines written by Armen A. Galoyan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the reviews: ""Brain Neurosecretory Cytokines is an excellent book, a veritable goldmine of information, at the cutting edge of neuroscience. It should stimulate ideas for future directions in neuroscience for years to come. This volume should be highly useful for medical libraries, neuroscientists, endocrinologists and graduate students in these fields."" (Arthur S. Brecher, TRENDS in Endocrinology & Metabolism, Vol. 16 (6), 2005)
Book Synopsis Epilepsy and Mental Retardation by : Matti Sillanpää
Download or read book Epilepsy and Mental Retardation written by Matti Sillanpää and published by Routledge. This book was released on 1999 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest in our successful series of epilepsy edited by this experienced Scandinavian group addressed the clinically challenging area of epilepsy in mentally retarded patients. While epilepsy and intellectual disability are frequently comorbid (each may precipitate the other and both can be a consequence of brain damage), their elucidation can be complex; there is a high risk of misdiagnosis due to the occurence in mentally retarded patients of paroxysmal phenomena which resemble epileptic seizures, and the presentation of other psychiatric problems can obscure symptoms of epilepsy. Treatment too, is problematic with a tendency towards polytherapy with its increased risk of undesirable side effects which are less easily discovered and poorly tolerated in mentally retarded patients.Such patients have in the past usually been institutionalized but they are now more often in ambulatory or primary care, There is thus a greater than ever need to recognize the particular difficulties involved withtheir care.This book clarifies interrelationships between mental retardation, intellectual deterioration, and epilepsy and delivers practical solutions to the problems associated with accurate diagnosis, treatment, and long term management of epilepsy in patients with intellectual disabilities.
Book Synopsis Unfolded Protein Response (UPR): An Impending Target for Multiple Neurological Disorders by : Safikur Rahman
Download or read book Unfolded Protein Response (UPR): An Impending Target for Multiple Neurological Disorders written by Safikur Rahman and published by Frontiers Media SA. This book was released on 2022-11-08 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: