Whole Genome Sequencing

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Next-Generation Genome Sequencing

Author : Michal Janitz
Publisher : John Wiley & Sons
ISBN 13 : 3527644733
Total Pages : 281 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Next-Generation Genome Sequencing by : Michal Janitz

Download or read book Next-Generation Genome Sequencing written by Michal Janitz and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.

Mapping and Sequencing the Human Genome

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Whole Genome Sequencing

Author : Joseph P. Damon
Publisher : Nova Science Publishers
ISBN 13 : 9781631171574
Total Pages : 0 pages
Book Rating : 4.1/5 (715 download)

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Book Synopsis Whole Genome Sequencing by : Joseph P. Damon

Download or read book Whole Genome Sequencing written by Joseph P. Damon and published by Nova Science Publishers. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the course of less than a decade, whole genome sequencing has progressed from being one of our nations boldest scientific aspirations to becoming a readily available technique for determining the complete sequence of an individuals deoxyribonucleic acid (DNA) -- that persons unique genetic blueprint. This book focuses on the privacy and progress in whole genome sequencing; and provides a scientific background for policymakers in genetic testing.

Clinical Genome Sequencing

Author : Aad Tibben
Publisher : Academic Press
ISBN 13 : 9780128133354
Total Pages : 0 pages
Book Rating : 4.1/5 (333 download)

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Book Synopsis Clinical Genome Sequencing by : Aad Tibben

Download or read book Clinical Genome Sequencing written by Aad Tibben and published by Academic Press. This book was released on 2019-04-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.

Sequence — Evolution — Function

Author : Eugene V. Koonin
Publisher : Springer Science & Business Media
ISBN 13 : 1475737831
Total Pages : 482 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Sequence — Evolution — Function by : Eugene V. Koonin

Download or read book Sequence — Evolution — Function written by Eugene V. Koonin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Genome Sequencing Technology and Algorithms

Author : Sun Kim
Publisher : Artech House Publishers
ISBN 13 :
Total Pages : 288 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Genome Sequencing Technology and Algorithms by : Sun Kim

Download or read book Genome Sequencing Technology and Algorithms written by Sun Kim and published by Artech House Publishers. This book was released on 2008 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2003 completion of the Human Genome Project was just one step in the evolution of DNA sequencing. This trailblazing work gives researchers unparalleled access to state-of-the-art DNA sequencing technologies, new algorithmic sequence assembly techniques, and emerging methods for both resequencing and genome analysis.

The Yeast Two-hybrid System

Author : Paul L. Bartel
Publisher : Oxford University Press, USA
ISBN 13 : 9780195109382
Total Pages : 362 pages
Book Rating : 4.1/5 (93 download)

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Book Synopsis The Yeast Two-hybrid System by : Paul L. Bartel

Download or read book The Yeast Two-hybrid System written by Paul L. Bartel and published by Oxford University Press, USA. This book was released on 1997 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, part of the Advances in Molecular Biology series, presents work by pioneers in the field and is the first publication devoted solely to the yeast two-hybrid system. It includes detailed protocols, practical advice on troubleshooting, and suggestions for future development. In addition, it illustrates how to construct an activation domain hybrid library, how to identify mutations that disrupt an interaction, and how to use the system in mammalian cells. Many of the contributors have developed new applications and variations of the technique.

Next Generation Sequencing and Whole Genome Selection in Aquaculture

Author : Zhanjiang (John) Liu
Publisher : John Wiley and Sons
ISBN 13 : 0470958928
Total Pages : 248 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Next Generation Sequencing and Whole Genome Selection in Aquaculture by : Zhanjiang (John) Liu

Download or read book Next Generation Sequencing and Whole Genome Selection in Aquaculture written by Zhanjiang (John) Liu and published by John Wiley and Sons. This book was released on 2010-12-01 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in DNA marker technologies, in particular the emergence of Single Nucleotide Polymorphism (SNP) discovery, have rendered some of the traditional methods of genetic research outdated. Next Generation Sequencing and Whole Genome Selection in Aquaculture comprehensively covers the current state of research in whole genome selection and applies these discoveries to the aquaculture industry specifically. The text begins with a thorough review of SNP and transitions into topics such as next generation sequencing, EST data mining, SNP quality assessment, and whole genome selection principles. Ending with a discussion of the technology's specific applications to the industry, this text will be a valuable reference for those involved in all aspects of aquaculture research. Special Features: Unique linking of SNP technologies, next generation sequencing technologies, and whole genome selection in the context of aquaculture research Thorough review of Single Nucleotide Polymorphism and existing research 8-page color plate section featuring detailed illustrations

The Soybean Genome

Author : Henry T. Nguyen
Publisher : Springer
ISBN 13 : 3319641980
Total Pages : 211 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis The Soybean Genome by : Henry T. Nguyen

Download or read book The Soybean Genome written by Henry T. Nguyen and published by Springer. This book was released on 2017-09-20 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the application of soybean genome sequences to comparative, structural, and functional genomics. Since the availability of the soybean genome sequence has revolutionized molecular research on this important crop species, the book also describes how the genome sequence has shaped research on transposon biology and applications for gene identification, tilling and positional gene cloning. Further, the book shows how the genome sequence influences research in the areas of genetic mapping, marker development, and genome-wide association mapping for identifying important trait genes and soybean breeding. In closing, the economic and botanical aspects of the soybean are also addressed.

Precision Cancer Medicine

Author : Sameek Roychowdhury
Publisher : Springer Nature
ISBN 13 : 3030236374
Total Pages : 196 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Precision Cancer Medicine by : Sameek Roychowdhury

Download or read book Precision Cancer Medicine written by Sameek Roychowdhury and published by Springer Nature. This book was released on 2020-01-02 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic sequencing technologies have augmented the classification of cancer beyond tissue of origin and towards a molecular taxonomy of cancer. This has created opportunities to guide treatment decisions for individual patients with cancer based on their cancer’s unique molecular characteristics, also known as precision cancer medicine. The purpose of this text will be to describe the contribution and need for multiple disciplines working together to deliver precision cancer medicine. This entails a multi-disciplinary approach across fields including molecular pathology, computational biology, clinical oncology, cancer biology, drug development, genetics, immunology, and bioethics. Thus, we have outlined a current text on each of these fields as they work together to overcome various challenges and create opportunities to deliver precision cancer medicine. As trainees and junior faculty enter their respective fields, this text will provide a framework for understanding the role and responsibility for each specialist to contribute to this team science approach.

The $1,000 Genome

Author : Kevin Davies
Publisher : Simon and Schuster
ISBN 13 : 1416569618
Total Pages : 352 pages
Book Rating : 4.4/5 (165 download)

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Book Synopsis The $1,000 Genome by : Kevin Davies

Download or read book The $1,000 Genome written by Kevin Davies and published by Simon and Schuster. This book was released on 2015-08-18 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2000, President Bill Clinton signaled the completion of the Human Genome Project at a cost in excess of $2 billion. A decade later, the price for any of us to order our own personal genome sequence--a comprehensive map of the 3 billion letters in our DNA--is rapidly and inevitably dropping to just $1,000. Dozens of men and women--scientists, entrepreneurs, celebrities, and patients--have already been sequenced, pioneers in a bold new era of personalized genomic medicine. The $1,000 genome has long been considered the tipping point that would open the floodgates to this revolution. Do you have gene variants associated with Alzheimer's or diabetes, heart disease or cancer? Which drugs should you consider taking for various diseases, and at what dosage? In the years to come, doctors will likely be able to tackle all of these questions--and many more--by using a computer in their offices to call up your unique genome sequence, which will become as much a part of your medical record as your blood pressure.

Next Generation Sequencing and Sequence Assembly

Author : Ali Masoudi-Nejad
Publisher : Springer Science & Business Media
ISBN 13 : 1461477263
Total Pages : 92 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Next Generation Sequencing and Sequence Assembly by : Ali Masoudi-Nejad

Download or read book Next Generation Sequencing and Sequence Assembly written by Ali Masoudi-Nejad and published by Springer Science & Business Media. This book was released on 2013-07-09 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about sequencing and assembly methods together, helps both biologists and computer scientists to get a clear idea about the field. Chapters will include information about new sequencing technologies such as ChIp-seq, ChIp-chip, and De Novo sequence assembly.

Bioinformatics for High Throughput Sequencing

Author : Naiara Rodríguez-Ezpeleta
Publisher : Springer Science & Business Media
ISBN 13 : 1461407826
Total Pages : 258 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Bioinformatics for High Throughput Sequencing by : Naiara Rodríguez-Ezpeleta

Download or read book Bioinformatics for High Throughput Sequencing written by Naiara Rodríguez-Ezpeleta and published by Springer Science & Business Media. This book was released on 2011-10-26 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. The generation of gigabases of sequence information for each of this huge bandwidth of applications in just a few days makes the development of bioinformatics applications for next generation sequencing data analysis as urgent as challenging.

Medical and Health Genomics

Author : Dhavendra Kumar
Publisher : Academic Press
ISBN 13 : 0127999221
Total Pages : 360 pages
Book Rating : 4.1/5 (279 download)

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Book Synopsis Medical and Health Genomics by : Dhavendra Kumar

Download or read book Medical and Health Genomics written by Dhavendra Kumar and published by Academic Press. This book was released on 2016-06-04 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

Computational Exome and Genome Analysis

Author : Peter N. Robinson
Publisher : CRC Press
ISBN 13 : 1351650815
Total Pages : 518 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Computational Exome and Genome Analysis by : Peter N. Robinson

Download or read book Computational Exome and Genome Analysis written by Peter N. Robinson and published by CRC Press. This book was released on 2017-09-13 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exome and genome sequencing are revolutionizing medical research and diagnostics, but the computational analysis of the data has become an extremely heterogeneous and often challenging area of bioinformatics. Computational Exome and Genome Analysis provides a practical introduction to all of the major areas in the field, enabling readers to develop a comprehensive understanding of the sequencing process and the entire computational analysis pipeline.

Whole Genome Sequencing

Author : Fouad Sabry
Publisher : One Billion Knowledgeable
ISBN 13 :
Total Pages : 386 pages
Book Rating : 4.:/5 (661 download)

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Book Synopsis Whole Genome Sequencing by : Fouad Sabry

Download or read book Whole Genome Sequencing written by Fouad Sabry and published by One Billion Knowledgeable. This book was released on 2022-10-05 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: What Is Whole Genome Sequencing The process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a single time is referred to as whole genome sequencing (WGS), full genome sequencing, complete genome sequencing, or entire genome sequencing. Other names for this process include entire genome sequencing, complete genome sequencing, and full genome sequencing. In order to do this, the chromosomal DNA of an organism, as well as the DNA found in the mitochondria and, in the case of plants, the chloroplasts, must be sequenced. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Whole genome sequencing Chapter 2: Genome Chapter 3: Human genome Chapter 4: Genomics Chapter 5: Molecular genetics Chapter 6: BGI Group Chapter 7: Gene duplication Chapter 8: DNA sequencing Chapter 9: Gene Chapter 10: Personal genomics Chapter 11: 1000 Genomes Project Chapter 12: Exome Chapter 13: Complete Genomics Chapter 14: Cancer genome sequencing Chapter 15: Exome sequencing Chapter 16: $1,000 genome Chapter 17: Single cell sequencing Chapter 18: Variant of uncertain significance Chapter 19: Whole genome bisulfite sequencing Chapter 20: Plant genome assembly Chapter 21: Personalized onco-genomics (II) Answering the public top questions about whole genome sequencing. (III) Real world examples for the usage of whole genome sequencing in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of whole genome sequencing' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of whole genome sequencing.

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

Author : Sorin Hostiuc
Publisher : Academic Press
ISBN 13 : 0128137657
Total Pages : 431 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies by : Sorin Hostiuc

Download or read book Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies written by Sorin Hostiuc and published by Academic Press. This book was released on 2018-08-07 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students. As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource. Provides practical analysis of the ethical issues raised by cutting-edge techniques and recent advances in prenatal and reproductive genetics Contains contributions from leading bioethicists and clinicians who offer a global, holistic perspective on applied challenges and moral questions relating to genetic and genomic reproductive technology Discusses preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, ethical issues, and more