“What is Damage suppressor Protein?-A Tardigrade (water bear)-Unique DNA-associated Protein improves Radiotolerance in Human-cultured cells.’’

Download “What is Damage suppressor Protein?-A Tardigrade (water bear)-Unique DNA-associated Protein improves Radiotolerance in Human-cultured cells.’’ PDF Online Free

Author :
Publisher : Dr.Hakim Saboowala
ISBN 13 :
Total Pages : 45 pages
Book Rating : 4./5 ( download)

DOWNLOAD NOW!


Book Synopsis “What is Damage suppressor Protein?-A Tardigrade (water bear)-Unique DNA-associated Protein improves Radiotolerance in Human-cultured cells.’’ by : Dr.Hakim Saboowala

Download or read book “What is Damage suppressor Protein?-A Tardigrade (water bear)-Unique DNA-associated Protein improves Radiotolerance in Human-cultured cells.’’ written by Dr.Hakim Saboowala and published by Dr.Hakim Saboowala. This book was released on 2020-02-02 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic DNA (Genomic deoxyribonucleic acid is chromosomal DNA, in contrast to extra-chromosomal DNAs like plasmids, abbreviated as gDNA) stores all genetic information and is indispensable for maintenance of normal cellular activity and propagation. Radiation causes severe DNA lesions, including double-strand breaks, and leads to genome instability and even lethality. Regardless of the toxicity of radiation, some organisms exhibit extraordinary tolerance against radiation. · These organisms are supposed to possess special mechanisms to mitigate radiation-induced DNA damages. Extensive study using radio-tolerant bacteria suggested that effective protection of proteins and enhanced DNA repair system play important roles in tolerability against high-dose radiation. Recent studies using an extremotolerant animal, the tardigrade, provides new evidence that a tardigrade-unique DNA-associating protein, termed Dsup, suppresses the occurrence of DNA breaks by radiation in human-cultured cells. An attempt has been made in this Booklet to provide a brief summary of the current knowledge on extremely radiotolerant animals, and present novel insights from the tardigrade research, which expand our understanding on molecular mechanism of exceptional radio-tolerability. ……. Dr. H. K. Saboowala.M.B.(BoM) M.R.S.H.(London)

Biotechnological Applications of Extremophilic Microorganisms

Download Biotechnological Applications of Extremophilic Microorganisms PDF Online Free

Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110424339
Total Pages : 424 pages
Book Rating : 4.1/5 (14 download)

DOWNLOAD NOW!


Book Synopsis Biotechnological Applications of Extremophilic Microorganisms by : Natuschka M. Lee

Download or read book Biotechnological Applications of Extremophilic Microorganisms written by Natuschka M. Lee and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-26 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad overview how extremophiles can be used in biotechnology, including for the production and degradation of compounds. It reviews various recent discoveries and applications related to a large variety of extremophiles, considering both prokaryotes as well as eukaryotes.

The Impact of the Space Environment on Microbial Growth and Behavior

Download The Impact of the Space Environment on Microbial Growth and Behavior PDF Online Free

Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832547141
Total Pages : 160 pages
Book Rating : 4.8/5 (325 download)

DOWNLOAD NOW!


Book Synopsis The Impact of the Space Environment on Microbial Growth and Behavior by : Camilla Urbaniak

Download or read book The Impact of the Space Environment on Microbial Growth and Behavior written by Camilla Urbaniak and published by Frontiers Media SA. This book was released on 2024-04-02 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microorganisms play an important role in life on Earth and can adapt and survive in harsh and changing environments. Their aptitude to thrive under hostile conditions is reflected by their survival and activity in some of the most extreme environments on Earth and their presence and growth in low earth orbit and outer space. Spaceflight and the space environment have a unique set of stressors compared to Earth (microgravity, galactic cosmic radiation, solar UV radiation, space vacuum, thermal extremes) that microbes are exposed to, but how they adapt and respond is still poorly understood. Studies to date, though, have shown that these responses can range from being beneficial for human exploration to negatively impact long duration missions. Hence, investigating the reaction of microorganisms to space conditions, the alterations in their physiology and virulence, not only helps shed light on the molecular basis of tolerance, but has implications for both space exploration and astrobiological missions.

Radiobiology Textbook

Download Radiobiology Textbook PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3031188101
Total Pages : 687 pages
Book Rating : 4.0/5 (311 download)

DOWNLOAD NOW!


Book Synopsis Radiobiology Textbook by : Sarah Baatout

Download or read book Radiobiology Textbook written by Sarah Baatout and published by Springer Nature. This book was released on 2023-09-23 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook focuses on the various aspects of radiobiology. The goal of radiobiological research is to better understand the effects of radiation exposure at the cellular and molecular levels in order to determine the impact on health. This book offers a unique perspective, by covering not only radiation biology but also radiation physics, radiation oncology, radiotherapy, radiochemistry, radiopharmacy, nuclear medicine, space radiation biology & physics, environmental and human radiation protection, nuclear emergency planning, molecular biology and bioinformatics, as well as the ethical, legal and social considerations related to radiobiology. This range of disciplines contributes to making radiobiology a broad and rather complex topic. This textbook is intended to provide a solid foundation to those interested in the basics and practice of radiobiological science. It is a learning resource, meeting the needs of students, scientists and medical staff with an interest in this rapidly evolving discipline, as well as a teaching tool, with accompanying teaching material to help educators.

Water Bears: The Biology of Tardigrades

Download Water Bears: The Biology of Tardigrades PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319957023
Total Pages : 419 pages
Book Rating : 4.3/5 (199 download)

DOWNLOAD NOW!


Book Synopsis Water Bears: The Biology of Tardigrades by : Ralph O. Schill

Download or read book Water Bears: The Biology of Tardigrades written by Ralph O. Schill and published by Springer. This book was released on 2019-02-14 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering extensive information on tardigrades, this volume begins with a chapter on the history of tardigrades, from the first description by Goeze in 1773, until 1929, when the most comprehensive monographic approach by E. Marcus was published. Tardigrades’ organ systems, including their integument, body cavity, digestive, muscular, nervous and reproductive systems, as well as their overall external morphology, are summarized in the second chapter. Subsequent chapters present the current state of knowledge on tardigrade phylogeny, biogeography, paleontology, cytology and cytogenetics. In addition, the book provides insights into the ecology of tardigrades in marine, freshwater and terrestrial habitats. The reproduction, development and life cycles are summarized and the extraordinary environmental adaptations of encystment and cyclomorphosis, desiccation tolerance, freezing tolerance and radiation tolerance are discussed in detail. Further chapters provide an overview of key approaches in molecular tardigrade studies and describe techniques for sampling and sample processing. The book closes with a list of tardigrade taxa up to a sub-generic level, including the type species of each genus, the numbers of lower taxa in each taxon, and the main environments in which the taxa were found. Given its depth of coverage, the volume offers an invaluable resource for scientists from various disciplines who plan to research tardigrades, and for all others who are interested in these fascinating animals.

Human Enhancements for Space Missions

Download Human Enhancements for Space Missions PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030420361
Total Pages : 295 pages
Book Rating : 4.0/5 (34 download)

DOWNLOAD NOW!


Book Synopsis Human Enhancements for Space Missions by : Konrad Szocik

Download or read book Human Enhancements for Space Missions written by Konrad Szocik and published by Springer Nature. This book was released on 2020-08-07 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a collection of chapters, which address various contexts and challenges of the idea of human enhancement for the purposes of human space missions. The authors discuss pros and cons of mostly biological enhancement of human astronauts operating in hostile space environments, but also ethical and theological aspects are addressed. In contrast to the idea and program of human enhancement on Earth, human enhancement in space is considered a serious and necessary option. This book aims at scholars in the following fields: ethics and philosophy, space policy, public policy, as well as biologists and psychologists.

Physiological and Biotechnological Aspects of Extremophiles

Download Physiological and Biotechnological Aspects of Extremophiles PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128183233
Total Pages : 388 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Physiological and Biotechnological Aspects of Extremophiles by : Richa Salwan

Download or read book Physiological and Biotechnological Aspects of Extremophiles written by Richa Salwan and published by Academic Press. This book was released on 2020-06-04 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiological and Biotechnological Aspects of Extremophiles highlights the current and topical areas of research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms of these fascinating organisms use to survive.The vast majority of extremophiles are microbes which include archaea, bacteria and some eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and even thrive. Extremophiles have important practical uses. They are a valuable source of industrially important enzymes and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining, and bioremediation.Aimed at research scientists, students, microbiologists, and biotechnologists, this book is an essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology, bioprospecting, biomining, biofuels, and extremozymes of these organisms. Shows the implications of the physiological adaptations of microbes from extreme habitats that are largely contributed by their biomolecules from basic to applied research Provides in-depth knowledge of genomic plasticity and proteome of different extremophiles Gives detailed and comprehensive insight about use of genetic engineering as well as genome editing for industrial applications

Exploring the World of Biology

Download Exploring the World of Biology PDF Online Free

Author :
Publisher : New Leaf Publishing Group
ISBN 13 : 1614581533
Total Pages : 158 pages
Book Rating : 4.6/5 (145 download)

DOWNLOAD NOW!


Book Synopsis Exploring the World of Biology by : John Hudson Tiner

Download or read book Exploring the World of Biology written by John Hudson Tiner and published by New Leaf Publishing Group. This book was released on 2008-11-01 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: DISCOVER THE WORLD OF LIFE AS GOD CREATED IT! The field of biology focuses on living things, from the smallest microscopic protozoa to the largest mammal. In this book you will read and explore the life of plants, insects, spiders and other arachnids, life in water, reptiles, birds, and mammals, highlighting God's amazing creatio. You will learn about the following and so much more: How does biological classification give each different type of plant or animal a unique name? In what ways are seeds spread around the world? What food does the body use for long-term storage of energy? How did biologists learn how the stomach digested food? What plant gave George de Mestral the idea for Velcro? For most of history, biologists used the visible appearance of plants or animals to classify them. They grouped plants or animals with similar-looking features into families. Starting in the 1990s, biologists have extracted DNA and RNA from cells as a guide to how plants or animals should be grouped. Like visual structures, these reveal the underlying design or creation. The newest book in our Exploring series, Exploring the World of Biology is a fascinating look at life - from the smallest proteins and spores, to the complex life systems of humans and animals.

Anhydrobiosis

Download Anhydrobiosis PDF Online Free

Author :
Publisher : Hutchinson Ross Publishing Company
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.:/5 (318 download)

DOWNLOAD NOW!


Book Synopsis Anhydrobiosis by : John H. Crowe

Download or read book Anhydrobiosis written by John H. Crowe and published by Hutchinson Ross Publishing Company. This book was released on 1973 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Evo-Devo: Non-model Species in Cell and Developmental Biology

Download Evo-Devo: Non-model Species in Cell and Developmental Biology PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030234592
Total Pages : 551 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!


Book Synopsis Evo-Devo: Non-model Species in Cell and Developmental Biology by : Waclaw Tworzydlo

Download or read book Evo-Devo: Non-model Species in Cell and Developmental Biology written by Waclaw Tworzydlo and published by Springer Nature. This book was released on 2019-10-09 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolutionary developmental biology or evo-devo is a field of biological research that compares the underlying mechanisms of developmental processes in different organisms to infer the ancestral condition of these processes and elucidate how they have evolved. It addresses questions about the developmental bases of evolutionary changes and evolution of developmental processes. The book’s content is divided into three parts, the first of which discusses the theoretical background of evo-devo. The second part highlights new and emerging model organisms in the evo-devo field, while the third and last part explores the evo-devo approach in a broad comparative context. To the best of our knowledge, no other book combines these three evo-devo aspects: theoretical considerations, a comprehensive list of emerging model species, and comparative analyses of developmental processes. Given its scope, the book will offer readers a new perspective on the natural diversity of processes at work in cells and during the development of various animal groups, and expand the horizons of seasoned and young researchers alike.

Cellular Biology of the Endoplasmic Reticulum

Download Cellular Biology of the Endoplasmic Reticulum PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 303067696X
Total Pages : 329 pages
Book Rating : 4.0/5 (36 download)

DOWNLOAD NOW!


Book Synopsis Cellular Biology of the Endoplasmic Reticulum by : Luis B. Agellon

Download or read book Cellular Biology of the Endoplasmic Reticulum written by Luis B. Agellon and published by Springer Nature. This book was released on 2021-05-29 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the biology of the endoplasmic reticulum (ER) and the associated ER proteins, it discusses their structure, function and signaling mechanisms in the cell and their role in disease. This book also offers insights into the practical aspects of research and demonstrates the use of non-mammalian models to study the structure and function of the ER. Written by leading experts in the field, the book enables readers to gain a thorough understanding of current ER biology. It is intended for scientists and clinical researchers working on the endoplasmic reticulum in all its various roles and facets in health and disease.

Dormancy and Resistance in Harsh Environments

Download Dormancy and Resistance in Harsh Environments PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642124224
Total Pages : 291 pages
Book Rating : 4.6/5 (421 download)

DOWNLOAD NOW!


Book Synopsis Dormancy and Resistance in Harsh Environments by : Esther Lubzens

Download or read book Dormancy and Resistance in Harsh Environments written by Esther Lubzens and published by Springer Science & Business Media. This book was released on 2010-07-30 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many organisms have evolved the ability to enter into and revive from a dormant state. They can survive for long periods in this state (often even months to years), yet can become responsive again within minutes or hours. This is often, but not necessarily, associated with desiccation. Preserving one’s body and reviving it in future generations is a dream of mankind. To date, however, we have failed to learn how cells, tissues or entire organisms can be made dormant or be effectively revived at ambient temperatures. In this book studies on organisms, ranging from aquatic cyanobacteria that produce akinetes to hibernating mammals, are presented, and reveal common but also divergent physiological and molecular pathways for surviving in a dormant form or for tolerating harsh environments. Attempting to learn the functions associated with dormancy and how they are regulated is one of the great future challenges. Its relevance to the preservation of cells and tissues is one of the key concerns of this book.

Polyextremophiles

Download Polyextremophiles PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 940076488X
Total Pages : 626 pages
Book Rating : 4.4/5 (7 download)

DOWNLOAD NOW!


Book Synopsis Polyextremophiles by : Joseph Seckbach

Download or read book Polyextremophiles written by Joseph Seckbach and published by Springer Science & Business Media. This book was released on 2013-05-13 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many Microorganisms and some macro-organisms can live under extreme conditions. For example, high and low temperature, acidic and alkaline conditions, high salt areas, high pressure, toxic compounds, high level of ionizing radiation, anoxia and absence of light, etc. Many organisms inhabit environments characterized by more than one form of stress (Polyextremophiles). Among them are those who live in hypersaline and alkaline, hot and acidic, cold/hot and high hydrostatic pressure, etc. Polyextremophiles found in desert regions have to copy with intense UV irradiation and desiccation, high as well as low temperatures, and low availability of water and nutrients. This book provides novel results of application to polyextremophiles research ranging from nanotechnology to synthetic biology to the origin of life and beyond.

Ecology and Evolution of Cancer

Download Ecology and Evolution of Cancer PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128043806
Total Pages : 292 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Ecology and Evolution of Cancer by : Beata Ujvari

Download or read book Ecology and Evolution of Cancer written by Beata Ujvari and published by Academic Press. This book was released on 2017-02-08 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies

Adaptive Oncogenesis

Download Adaptive Oncogenesis PDF Online Free

Author :
Publisher : Harvard University Press
ISBN 13 : 0674545397
Total Pages : 289 pages
Book Rating : 4.6/5 (745 download)

DOWNLOAD NOW!


Book Synopsis Adaptive Oncogenesis by : James DeGregori

Download or read book Adaptive Oncogenesis written by James DeGregori and published by Harvard University Press. This book was released on 2018-03-09 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Popular understanding holds that genetic changes create cancer. James DeGregori uses evolutionary principles to propose a new way of thinking about cancerÕs occurrence. Cancer is as much a disease of evolution as it is of mutation, one in which mutated cells outcompete healthy cells in the ecosystem of the bodyÕs tissues. His theory ties cancerÕs progression, or lack thereof, to evolved strategies to maximize reproductive success. Through natural selection, humans evolved genetic programs to maintain bodily health for as long as necessary to increase the odds of passing on our genesÑbut not much longer. These mechanisms engender a tissue environment that favors normal stem cells over precancerous ones. Healthy tissues thwart cancer cellsÕ ability to outcompete their precancerous rivals. But as our tissues age or accumulate damage from exposures such as smoking, normal stem cells find themselves less optimized to their ecosystem. Cancer-causing mutations can now help cells adapt to these altered tissue environments, and thus outcompete normal cells. Just as changes in a speciesÕ habitat favor the evolution of new species, changes in tissue environments favor the growth of cancerous cells. DeGregoriÕs perspective goes far in explaining who gets cancer, when it appears, and why. While we cannot avoid mutations, it may be possible to sustain our tissuesÕ natural and effective system of defense, even in the face of aging or harmful exposures. For those interested in learning how cancers arise within the human body, the insights in Adaptive Oncogenesis offer a compelling perspective.

Protein Dimerization and Oligomerization in Biology

Download Protein Dimerization and Oligomerization in Biology PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461432294
Total Pages : 184 pages
Book Rating : 4.4/5 (614 download)

DOWNLOAD NOW!


Book Synopsis Protein Dimerization and Oligomerization in Biology by : Jacqueline M. Matthews

Download or read book Protein Dimerization and Oligomerization in Biology written by Jacqueline M. Matthews and published by Springer Science & Business Media. This book was released on 2012-09-04 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Prebiotic Chemistry

Download Prebiotic Chemistry PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783540277590
Total Pages : 248 pages
Book Rating : 4.2/5 (775 download)

DOWNLOAD NOW!


Book Synopsis Prebiotic Chemistry by : Peter Walde

Download or read book Prebiotic Chemistry written by Peter Walde and published by Springer Science & Business Media. This book was released on 2005-10-13 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: