Vortex Formation In The Cardiovascular System

Download Vortex Formation In The Cardiovascular System full books in PDF, epub, and Kindle. Read online Vortex Formation In The Cardiovascular System ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Vortex Formation in the Cardiovascular System

Author : Arash Kheradvar
Publisher : Springer Science & Business Media
ISBN 13 : 1447122887
Total Pages : 166 pages
Book Rating : 4.4/5 (471 download)

DOWNLOAD NOW!

Book Synopsis Vortex Formation in the Cardiovascular System by : Arash Kheradvar

Download or read book Vortex Formation in the Cardiovascular System written by Arash Kheradvar and published by Springer Science & Business Media. This book was released on 2012-02-01 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vortex Formation in the Cardiovascular System will recapitulate the current knowledge about the vortex formation in the cardiovascular system, from mechanics to cardiology. This can facilitate the interaction between basic scientists and clinicians on the topic of the circulatory system. The book begins with a synopsis of the fundamentals aspects of fluid mechanics to give the reader the essential background to address the proceeding chapters. Then the fundamental elements of vortex dynamics will be discussed, explaining the conditions for their formation and the rules governing their dynamics. The main equations are accompanied by mathematical models. Cardiovascular vortex formation is first analyzed in physiological, healthy conditions in the heart chambers and in the large arterial vessels. The analysis is initially presented with an intuitive appeal grounded on the physical phenomena and a focus on its clinical significance.In the proceeding chapters, the knowledge gained from either clinical or basic science literature will be discussed. The corresponding mathematical elements will finally be presented to ensure the adequate diligence. The proceeding chapters ensue to the analysis of pathological conditions, when the reader may have developed the ability to recognize normal from abnormal vortex formation phenomenon. Pathological vortex formation represents vortices that develop at sites where normally laminar flow should exist, e.g. stenosis and aneurisms. This analysis naturally leads to the interaction of vortices due to the surgical procedures with respect to prediction of changes in vortex formation. The existing techniques, from medical imaging to numerical simulations, to explore vortex flows in the cardiovascular systems will also be described. The presentations are accompanied by the mathematical definitions can that be understandable for reader without the advanced mathematical background, while an interested reader with more advanced knowledge in mathematics can be referred to references for further quantitative analyses. The book pursues the objective to transfer the fundamental vortex formation phenomena with application to the cardiovascular system to the reader. This book will be a valuable support for physicians in the evaluation of vortex influence on diagnosis and therapeutic choices. At the same time, the book will provide the rigorous information for research scientists, either from medicine and mechanics, working on the cardiovascular circulation incurring with the physics of vortex dynamics.

Vortex Formation in the Cardiovascular System

Author : Arash Kheradvar
Publisher : Springer Science & Business Media
ISBN 13 : 1447122879
Total Pages : 176 pages
Book Rating : 4.4/5 (471 download)

DOWNLOAD NOW!

Book Synopsis Vortex Formation in the Cardiovascular System by : Arash Kheradvar

Download or read book Vortex Formation in the Cardiovascular System written by Arash Kheradvar and published by Springer Science & Business Media. This book was released on 2012-02-01 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vortex Formation in the Cardiovascular System will recapitulate the current knowledge about the vortex formation in the cardiovascular system, from mechanics to cardiology. This can facilitate the interaction between basic scientists and clinicians on the topic of the circulatory system. The book begins with a synopsis of the fundamentals aspects of fluid mechanics to give the reader the essential background to address the proceeding chapters. Then the fundamental elements of vortex dynamics will be discussed, explaining the conditions for their formation and the rules governing their dynamics. The main equations are accompanied by mathematical models. Cardiovascular vortex formation is first analyzed in physiological, healthy conditions in the heart chambers and in the large arterial vessels. The analysis is initially presented with an intuitive appeal grounded on the physical phenomena and a focus on its clinical significance.In the proceeding chapters, the knowledge gained from either clinical or basic science literature will be discussed. The corresponding mathematical elements will finally be presented to ensure the adequate diligence. The proceeding chapters ensue to the analysis of pathological conditions, when the reader may have developed the ability to recognize normal from abnormal vortex formation phenomenon. Pathological vortex formation represents vortices that develop at sites where normally laminar flow should exist, e.g. stenosis and aneurisms. This analysis naturally leads to the interaction of vortices due to the surgical procedures with respect to prediction of changes in vortex formation. The existing techniques, from medical imaging to numerical simulations, to explore vortex flows in the cardiovascular systems will also be described. The presentations are accompanied by the mathematical definitions can that be understandable for reader without the advanced mathematical background, while an interested reader with more advanced knowledge in mathematics can be referred to references for further quantitative analyses. The book pursues the objective to transfer the fundamental vortex formation phenomena with application to the cardiovascular system to the reader. This book will be a valuable support for physicians in the evaluation of vortex influence on diagnosis and therapeutic choices. At the same time, the book will provide the rigorous information for research scientists, either from medicine and mechanics, working on the cardiovascular circulation incurring with the physics of vortex dynamics.

Experimental Analysis Into the Main Artery of 2 Chamber Heart Model During Cardiac Cycle

Author : Quo Liang Loh
Publisher :
ISBN 13 :
Total Pages : 96 pages
Book Rating : 4.:/5 (953 download)

DOWNLOAD NOW!

Book Synopsis Experimental Analysis Into the Main Artery of 2 Chamber Heart Model During Cardiac Cycle by : Quo Liang Loh

Download or read book Experimental Analysis Into the Main Artery of 2 Chamber Heart Model During Cardiac Cycle written by Quo Liang Loh and published by . This book was released on 2013 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regarding to the report from World Health Organization (WHO), the most killer disease throughout the world is cardiovascular disease. There are millions of people deaths because of this disease every year. So, it is important to study the blood pumping mechanism in human body and what is the reason causing this device damage or fail to operate normally in detail. The objective of this study is to develop a heart model for investigating the patterns of fluid flow, and blood velocity diastolic. This heart model is able to observe the fluid flow pattern in left and right ventricle in a pressurized pulsate flow. A detail on fabrication, limitation, future improvement, and problem faced of heart model are discussed in this study. The whole system will be conduct in a close system which operated by using the combination of motor, and syringe. The results showed a relationship between heart beat, velocity, and blood vessel diameter especially for inferior, and superior vena cava can be establish. The result also proved that the relationship between heart beat and the velocity, and the difference of pressure between atrium and ventricle are directly proportional. Additionally, the relationship between vortex formation and septum in the heart chamber can be established at the end of this study. In conclusion, this study had succeeded to produce an equation relates to the velocity, diameter and heart beat in inferior, and superior vena cava. This result can contribute to future heart study as well as application in medical field.

Fluid Mechanics for Cardiovascular Engineering

Author : Gianni Pedrizzetti
Publisher : Springer Nature
ISBN 13 : 3030859436
Total Pages : 231 pages
Book Rating : 4.0/5 (38 download)

DOWNLOAD NOW!

Book Synopsis Fluid Mechanics for Cardiovascular Engineering by : Gianni Pedrizzetti

Download or read book Fluid Mechanics for Cardiovascular Engineering written by Gianni Pedrizzetti and published by Springer Nature. This book was released on 2021-10-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a guiding thread between the distant fields of fluid mechanics and clinical cardiology. Well rooted in the science of fluid dynamics, it drives the reader across progressively more realistic scenarios up to the complexity of routine medical applications. Based on the author’s 25 years of collaborations with cardiologists, it helps engineers learn communicating with clinicians, yet maintaining the rigor of scientific disciplines. This book starts with a description of the fundamental elements of fluid dynamics in large blood vessels. This is achieved by introducing a rigorous physical background accompanied by examples applied to the circulation, and by presenting classic and recent results related to the application of fluid dynamics to the cardiovascular physiology. It then explores more advanced topics for a physics-based understanding of phenomena effectively encountered in clinical cardiology. It stands as an ideal learning resource for physicists and engineers working in cardiovascular fluid dynamics, industry engineers working on biomedical/cardiovascular technology, and students in bio-fluid dynamics. Written with a concise style, this textbook is accessible to a broad readership, including students, physical scientists and engineers, offering an entry point into this multi-disciplinary field. It includes key concepts exemplified by illustrations using cutting-edge imaging, references to modelling and measurement technologies, and includes unique original insights.

Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges

Author : Oscar Camara
Publisher : Springer
ISBN 13 : 3642542689
Total Pages : 284 pages
Book Rating : 4.6/5 (425 download)

DOWNLOAD NOW!

Book Synopsis Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges by : Oscar Camara

Download or read book Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges written by Oscar Camara and published by Springer. This book was released on 2014-01-21 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the 4th International Workshop on Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges, STACOM 2013, held in conjunction with MICCAI 2013, in Nagoya, Japan, in September 2013. The 31 revised full papers were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on cardiac image processing; atlas construction; statistical modelling of cardiac function across different patient populations; cardiac mapping; cardiac computational physiology; model customization; atlas based functional analysis; ontological schemata for data and results; integrated functional and structural analyses; as well as the pre-clinical and clinical applicability of these methods.

Coherent Vortex Structures in Fluids and Plasmas

Author : Anatoli Tur
Publisher : Springer
ISBN 13 : 3319527339
Total Pages : 313 pages
Book Rating : 4.3/5 (195 download)

DOWNLOAD NOW!

Book Synopsis Coherent Vortex Structures in Fluids and Plasmas by : Anatoli Tur

Download or read book Coherent Vortex Structures in Fluids and Plasmas written by Anatoli Tur and published by Springer. This book was released on 2017-04-09 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph introduces readers to the hydrodynamics of vortex formation, and reviews the last decade of active research in the field, offering a unique focus on research topics at the crossroads of traditional fluids and plasmas. Vortices are responsible for the process of macroscopic transport of momentum, energy and mass, and are formed as the result of spontaneous self-organization. Playing an important role in nature and technology, localized, coherent vortices are regularly observed in shear flows, submerged jets, afterbody flows and in atmospheric boundary layers, sometimes taking on the form of vortex streets. In addition, the book addresses a number of open issues, including but not limited to: which singularities are permitted in a 2D Euler equation besides point vortices? Which other, even more complex, localized vortices could be contained in the Euler equation? How do point vortices interact with potential waves?

Numerical Investigation of Vortex Formation with Application to Left Ventricle Filling

Author : Lucas Ian Farrar
Publisher :
ISBN 13 :
Total Pages : 206 pages
Book Rating : 4.:/5 (1 download)

DOWNLOAD NOW!

Book Synopsis Numerical Investigation of Vortex Formation with Application to Left Ventricle Filling by : Lucas Ian Farrar

Download or read book Numerical Investigation of Vortex Formation with Application to Left Ventricle Filling written by Lucas Ian Farrar and published by . This book was released on 2017 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

TEXTBOOK OF BIOCHEMISTRY, BIOTECHNOLOGY, ALLIED AND MOLECULAR MEDICINE

Author : TALWAR, G.P.
Publisher : PHI Learning Pvt. Ltd.
ISBN 13 : 8120351258
Total Pages : 1593 pages
Book Rating : 4.1/5 (23 download)

DOWNLOAD NOW!

Book Synopsis TEXTBOOK OF BIOCHEMISTRY, BIOTECHNOLOGY, ALLIED AND MOLECULAR MEDICINE by : TALWAR, G.P.

Download or read book TEXTBOOK OF BIOCHEMISTRY, BIOTECHNOLOGY, ALLIED AND MOLECULAR MEDICINE written by TALWAR, G.P. and published by PHI Learning Pvt. Ltd.. This book was released on 2015 with total page 1593 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourth Edition of the compendium pools together the knowledge and experience of experts from all over the world, who are engaged in teaching and research in the field of biochemistry, medical sciences and allied disciplines. Comprising 20 sections, the present edition of the book has been substantially revised incorporating the latest research and achievements in the field. Beginning appropriately with chemical architecture of the living systems, role and significance of biochemical reactions, organization of specialised tissues, and importance of food and nutrition, the book explores beyond traditional boundaries of biochemistry. The knowledge of various organ systems has been expanded covering their normal function, ailments and dysfunction. A chapter on Eye and Vision explaining molecular basis of cataract and glaucoma have been added. Also, the book introduces stem cells and regenerative therapy and defines molecules associated with pleasure, happiness, stress and anxiety. A Section on Gastrointestinal and Biliary System elaborates on physiology and dysfunction including fatty liver and its implications, and hepatitis viruses. The knowledge of Human Genetics and Biochemical Basis of Inheritance has been appropriately expanded to reflect the latest advances in various domains. Besides DNA fingerprinting for identity establishment, the Section discusses epigenetics, micro-RNA and siRNA including their role in gene expression, chromatin modification and its association with human diseases, and genetic engineering. It also explores emerging areas such as metabolomics and proteomics; synthetic biology; and dual use technology in bioterrorism. Due emphasis has been given to the Section on Cell Replication and Cancer. Emergence of the use of probiotics in human health has also been highlighted. Besides, an entire Section has been devoted to male and female reproductive systems, fertilization, implantation, pregnancy, lactation, and assisted reproductive technology. Immunology, including vaccines and immunization, has been given due attention with latest updates in this fast growing area. Modern medicine, despite its stupendous advances cannot provide cure for all ailments. Thus, the new edition provides knowledge of alternative medicine systems—Ayurveda, Homeopathy, Unani, Yoga and Herbal Medicine. Incorporating vast information on the latest and emerging areas, the book will be of immense value to the students of medical sciences not only in their preclinical years, but also in all phases of medical course including postgraduate education and practice. Besides, it will also serve as a valuable source to the students of biochemistry and human bi

Principles of Heart Valve Engineering

Author : Arash Kheradvar
Publisher : Academic Press
ISBN 13 : 0128146621
Total Pages : 414 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Principles of Heart Valve Engineering by : Arash Kheradvar

Download or read book Principles of Heart Valve Engineering written by Arash Kheradvar and published by Academic Press. This book was released on 2019-08-28 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts. Covers the depth and breadth of this interdisciplinary area of research Encompasses a wide range of topics, from basic science, to the translational applications of heart valve engineering Contains contributions from leading experts in the field that are heavily illustrated

Ultrafast Ultrasound Imaging

Author : Hideyuki Hasegawa
Publisher : MDPI
ISBN 13 : 3038971278
Total Pages : 185 pages
Book Rating : 4.0/5 (389 download)

DOWNLOAD NOW!

Book Synopsis Ultrafast Ultrasound Imaging by : Hideyuki Hasegawa

Download or read book Ultrafast Ultrasound Imaging written by Hideyuki Hasegawa and published by MDPI. This book was released on 2018-09-21 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Ultrafast Ultrasound Imaging" that was published in Applied Sciences

Numerical Haemodynamics in the Human Heart

Author : Daub, Anna Christina
Publisher : KIT Scientific Publishing
ISBN 13 : 3731507579
Total Pages : 198 pages
Book Rating : 4.7/5 (315 download)

DOWNLOAD NOW!

Book Synopsis Numerical Haemodynamics in the Human Heart by : Daub, Anna Christina

Download or read book Numerical Haemodynamics in the Human Heart written by Daub, Anna Christina and published by KIT Scientific Publishing. This book was released on 2018-03-21 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The characteristic vortex formation in the ventricles is believed to be affected at an early stage of heart diseases. First, post-processing of patient-specific data has to be standardised. The chosen methods, a combination of Eulerian and Lagrangian techniques, are characterised by means of necessary spatial and temporal resolutions. Second, the goal is to find the best cost-benefit approach for modelling of the mitral valve, as it affects vortex formation and progression in the left ventricle.

Numerical Haemodynamics in the Human Heart

Author : Anna Christina Daub
Publisher :
ISBN 13 : 9781013278907
Total Pages : 194 pages
Book Rating : 4.2/5 (789 download)

DOWNLOAD NOW!

Book Synopsis Numerical Haemodynamics in the Human Heart by : Anna Christina Daub

Download or read book Numerical Haemodynamics in the Human Heart written by Anna Christina Daub and published by . This book was released on 2020-10-09 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: The characteristic vortex formation in the ventricles is believed to be affected at an early stage of heart diseases. First, post-processing of patient-specific data has to be standardised. The chosen methods, a combination of Eulerian and Lagrangian techniques, are characterised by means of necessary spatial and temporal resolutions. Second, the goal is to find the best cost-benefit approach for modelling of the mitral valve, as it affects vortex formation and progression in the left ventricle. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Heart's Vortex

Author : Ares Pasipoularides
Publisher : PMPH-USA
ISBN 13 : 9781607950332
Total Pages : 958 pages
Book Rating : 4.9/5 (53 download)

DOWNLOAD NOW!

Book Synopsis Heart's Vortex by : Ares Pasipoularides

Download or read book Heart's Vortex written by Ares Pasipoularides and published by PMPH-USA. This book was released on 2009-11 with total page 958 pages. Available in PDF, EPUB and Kindle. Book excerpt: This outstanding resource provides a comprehensive guide to intracardiac blood flow phenomena and cardiac hemodynamics, including the developmental history, theoretical frameworks, computational fluid dynamics, and practical applications for clinical cardiology, cardiac imaging and embryology. It is not a mere compilation of the most up-to-date scientific data and relevant concepts. Rather, it is an integrated educational means to developing pluridisciplinary background, knowledge, and understanding. Such understanding allows an appreciation of the crucial, albeit heretofore generally unappreciated, importance of intracardiac blood flow phenomena in a host of multifaceted functional and morphogenetic cardiac adaptations. The book includes over 400 figures, which were prepared by the author and form a vital part of the pedagogy. It is organized in three parts. Part I, Fundamentals of Intracardiac Flows and Their Measurement, provides comprehensive background from many disciplines that are necessary for a deep and broad understanding and appreciation of intracardiac blood flow phenomena. Such indispensable background spans several chapters and covers necessary mathematics, a brief history of the evolution of ideas and methodological approaches that are relevant to cardiac fluid dynamics and imaging, a qualitative introduction to fluid dynamic stability theory, chapters on physics and fluid dynamics of unsteady blood flows and an intuitive introduction to various kinds of relevant vortical fluid motions. Part II, Visualization of Intracardiac Blood Flows: Methodologies, Frameworks and Insights, is devoted to pluridisciplinary approaches to the visualization of intracardiac blood flows. It encompasses chapters on 3-D real-time and "live 3-D" echocardiography and Doppler echocardiography, CT tomographic scanning modalities, including multidetector spiral/helical dataset acquisitions, MRI and cardiac MRA, including phase contrast velocity mapping (PCVM), etc. An entire chapter is devoted to the understanding of post processing exploration techniques and the display of tomographic data, including "slice-and-dice" 3-D techniques and cine-MRI. Part II also encompasses an intuitive introduction to CFD as it pertains to intracardiac blood flow simulations, followed--in separate chapters--by conceptually rich treatments of the computational fluid dynamics of ejection and of diastolic filling. An entire chapter is devoted to fluid dynamic epigenetic factors in cardiogenesis and pre- and postnatal cardiac remodeling, and another to clinical and basic science perspectives, and their implications for emerging research frontiers. Part III contains an Appendix presenting technical aspects of the method of predetermined boundary motion, "PBM," developed at Duke University by the author and his collaborators.

Vortex Formation in the Starting Flow of Rotating, Low-Aspect-Ratio Plates

Author : Adam DeVoria
Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.:/5 (79 download)

DOWNLOAD NOW!

Book Synopsis Vortex Formation in the Starting Flow of Rotating, Low-Aspect-Ratio Plates by : Adam DeVoria

Download or read book Vortex Formation in the Starting Flow of Rotating, Low-Aspect-Ratio Plates written by Adam DeVoria and published by . This book was released on 2011 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-dimensional vortex formation of a low-aspect-ratio (AR = 1.7), trapezoidal flat plate performing low Reynolds number (order 10^3) pure rotation from rest at a 90° angle of attack and is experimentally investigated. The objectives are to characterize the time-dependent, three-dimensional vortex structure as the plate motion progresses, to ascertain the ramifications of the significant root-to-tip flow on the vortex formation, and to determine the presence of and subsequently investigate any evidence of vortex saturation ("formation parameter") effects. The experiments are conducted in a glass water tank facility, and the diagnostics tools used are dye flow visualization and planar digital particle image velocimetry (DPIV). The vortex structures created by the low-aspect-ratio plate are symmetric ring-like vortices comprised mainly of vorticity generated at the tip edge of the plate. For large rotation amplitudes the dye flow visualization shows the shedding of this ring-like vortex end even the generation of a secondary ring-like vortex, all while the plate is still in motion, indicating the saturation of the primary vortex. The time-varying vortex circulation, calculated from the DPIV measurements in the symmetry plane of the flow, provides quantitative evidence of vortex saturation. It was found that the temporal development of the vortex circulation is complex, which obscures the objective determination of physically relevant saturation times. This difficulty is a direct result of an interaction between the evolving formation of the final ring-like vortex via Kelvin-Helmholtz-like instabilities that are inherent in the separated shear layers emanating from the free edges of the plate, and the strong root-to-tip flow, which is induced by the tip-edge- and side-edge-vortices.

Vortex Dynamics Theories and Applications

Author : Zambri Harun
Publisher : BoD – Books on Demand
ISBN 13 : 183962616X
Total Pages : 236 pages
Book Rating : 4.8/5 (396 download)

DOWNLOAD NOW!

Book Synopsis Vortex Dynamics Theories and Applications by : Zambri Harun

Download or read book Vortex Dynamics Theories and Applications written by Zambri Harun and published by BoD – Books on Demand. This book was released on 2020-12-09 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprises of different areas in which vortex dynamics is important, its generation, evolution, interactions with other motions, and finally the ways it can be controlled. Vortex characteristics are important in many aspects of our lives, from blood circulation in the arteries to the high-speed jet. Flow control and manipulation of vortices have been used to reduce drag for large tankers resulting in billions of dollars in savings. An effective smoke management system must be put in place for critical areas to ensure the safety of people, for example in a very large shopping complex or a large airport. Advanced computational and cloud-computing facilities have contributed significantly to large-scale simulation projects. Therefore, validations could be performed for larger windows of study so that it can now cover the entire e.g. central business district (CBD) for urban heat island (UHI) study or land-ocean interactions.

Vortex Formation of the LVAD-assisted Left Ventricle Studied in a Cardiac Simulator

Author :
Publisher :
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4.:/5 (861 download)

DOWNLOAD NOW!

Book Synopsis Vortex Formation of the LVAD-assisted Left Ventricle Studied in a Cardiac Simulator by :

Download or read book Vortex Formation of the LVAD-assisted Left Ventricle Studied in a Cardiac Simulator written by and published by . This book was released on 2013 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart transplantation remains the primary treatment for heart failure (HF), a deadly disease in which the heart fails to pump sufficient blood to meet the body's needs. Unfortunately, of the 600,000 new HF patients per year, only 2200 (0.3%) of them receive heart transplantation. The critical organ shortage presents a need for artificial devices. Left ventricular assist devices (LVADs) are implantable blood pumps that serve as an alternative treatment for HF. Unfortunately, stroke is a devastating complication that occurs in about 17-20% of LVAD patients. Since stroke is the result of blood vessel blockage, we hypothesize that LVADs create flow disturbances such as localized stagnation regions that encourages excessive blood clotting (thrombosis) in the LV, which detach and release into the bloodstream. Experiments were performed using the in vitro SDSU cardiac simulator, which reproduces the flow and hemodynamics of a left ventricle attached to a HeartMate II LVAD. The effect of LVAD support on LV flow patterns was assessed by varying the LVAD speed from low (6500rpm) to high (12500rpm). Particle Image Velocimetry was used to image 2-D fluid structures in the LV model. Briefly, fluorescent tracer particles were seeded into the simulator, the particles were illuminated by a laser plane and their motion captured by a high frame-rate camera. Localized stagnation was measured by the stagnicity (S[subscript I], defined as the reciprocal of average velocity within the region of interest. The flow patterns resemble a HF patient as the ventricular inflow jet follows an asymmetric recirculation pattern that redirects the momentum of the fluid stream to the LV outflow tract (LVOT). Once the LVAD is incorporated into the circulation, the fluid stream bifurcates into ventricular outflow and LVAD outflow. As LVAD speed increases further, more fluid is ejected through the LVAD until finally there is a complete series flow. We observe a local stagnation region in the LVOT regardless of LVAD speed. The level of stagnation increases progressively from Pre-LVAD (S[subscript I] =4.20(m/s)−1), parallel (S[subscript I] =4.75 (m/s)−1), to series flow (SI =7.75 (m/s)−1). The results suggest that LVAD support alters the cardiac ejection pathways and increases the risk of thrombosis within the left ventricle.

Spirals and Vortices

Author : Kinko Tsuji
Publisher : Springer
ISBN 13 : 3030057984
Total Pages : 297 pages
Book Rating : 4.0/5 (3 download)

DOWNLOAD NOW!

Book Synopsis Spirals and Vortices by : Kinko Tsuji

Download or read book Spirals and Vortices written by Kinko Tsuji and published by Springer. This book was released on 2019-04-04 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated book explores the fascinating and ubiquitous occurrence of spirals and vortices in human culture and in nature. Spiral forms have been used as elements in the arts for thousands of years, whereas their role in nature and science – from DNA and sea shells to galaxies – is still a topic of investigation in numerous fields. Following an introduction to the cultural history of spiral forms, the book presents contributions from leading experts, who describe the origins, mechanisms and dynamics of spirals and vortices in their special fields. As a whole the book provides a valuable source of information, while also taking the reader on an aesthetic and scientific journey through the world of spiral forms.