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Viral Fitness And Evolution
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Book Synopsis Origin and Evolution of Viruses by : Esteban Domingo
Download or read book Origin and Evolution of Viruses written by Esteban Domingo and published by Elsevier. This book was released on 2008-06-23 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. - NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution - UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups - SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts
Book Synopsis Viral Fitness and Evolution by : Esteban Domingo
Download or read book Viral Fitness and Evolution written by Esteban Domingo and published by Springer Nature. This book was released on 2023-01-02 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book unifies general concepts of plant and animal virus evolution and covers a broad range of topics related to theoretical and experimental aspects of virus population dynamics and viral fitness. Timely topics such as viral mechanisms to cope with antiviral agents, the adaptability of the virus to new hosts, emergence of new viral phenotypes, and the connections between short- and long-term virus evolution are included. By comparing plant and animal viruses, universal mechanisms responsible for fitness variations, viral emergence and disease mechanisms are explored. Although emphasis is put on specific plant and human viral pathogens, relevant similarities and differences to other viruses are highlighted. Additionally, readers will learn more about the adaptability of coronaviruses, including the recently emerged SARS-CoV-2, the causative agent of the COVID-19 pandemic. The book is aimed at students and scientists interested in basic and applied aspects of plant and animal virus population dynamics and evolution.
Book Synopsis Emerging Viruses by : Stephen S. Morse
Download or read book Emerging Viruses written by Stephen S. Morse and published by Oxford University Press. This book was released on 1996-08-01 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: New epidemics such as AIDS and "mad cow" disease have dramatized the need to explore the factors underlying rapid viral evolution and emerging viruses. This comprehensive volume is the first to describe this multifaceted new field. It places viral evolution and emergence in a historical context, describes the interaction of viruses with hosts, and details the advances in molecular biology and epidemiology that have provided the tools necessary to track developing viral epidemics and to detect new viruses far more successfully than could be done in the recent past. This unique book also lucidly details case histories and offers practical suggestions for the prevention of future epidemics. The contributors are leading authorities in their disciplines, and were selected both for their expert knowledge and for their ability to define and elucidate the fundamental issues. The book is highly accessible and has been written for a wide audience that includes virologists, public health authorities, medical anthropologists, evolutionary biologists, geneticists, infectious disease specialists, and social scientists interested in medical and health issues.
Book Synopsis Darwinian Dynamics by : Richard E. Michod
Download or read book Darwinian Dynamics written by Richard E. Michod and published by Princeton University Press. This book was released on 2021-01-12 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of fitness has long been a topic of intense debate among evolutionary biologists and their critics, with its definition and explanatory power coming under attack. In this book, Richard Michod offers a fresh, dynamical interpretation of evolution and fitness concepts. He argues that evolution has no enduring products; what matters is the process of genetic change. Whereas many biologists have focused on competition and aggression as determining factors in survival, Michod, by concentrating on the emergence of individuality at new and more complex levels, finds that cooperation plays even a greater role. Michod first considers the principles behind the hierarchically nested levels of organization that constitute life: genes, chromosomes, genomes, cells, multicellular organisms, and societies. By examining the evolutionary transitions from the molecular level up to the whole organism, the author explains how cooperation and conflict in a multilevel setting leads to new levels of fitness. He builds a model of fitness drawing on recent developments in ecology and multilevel selection theory and on new explanations of the origin of life. Michod concludes with a discussion of the philosophical implications of his theory of fitness, a theory that addresses the most fundamental and unique concept in all of biology.
Book Synopsis Viruses and Apoptosis by : Covadonga Alonso
Download or read book Viruses and Apoptosis written by Covadonga Alonso and published by Springer Science & Business Media. This book was released on 2004-03-24 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using different viral models, molecular pathways regulated by viral genes and their role in the pathogenesis of infection are analyzed. The book also offers an update of known signaling pathways in apoptosis and their role in normal and infected cells. Special emphasis is given to molecular pathways underlying viral transformation and oncogenesis and how research in this area is opening opportunities in cancer therapy.
Book Synopsis Plant Virus Evolution by : Marilyn J. Roossinck
Download or read book Plant Virus Evolution written by Marilyn J. Roossinck and published by Springer Science & Business Media. This book was released on 2008-02-23 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive look at the field of plant virus evolution. It is the first book ever published on the topic. Individual chapters, written by experts in the field, cover plant virus ecology, emerging viruses, plant viruses that integrate into the host genome, population biology, evolutionary mechanisms and appropriate methods for analysis. It covers RNA viruses, DNA viruses, pararetroviruses and viroids, and presents a number of thought-provoking ideas.
Book Synopsis Viruses and the Evolution of Life by : Luis P. Villarreal
Download or read book Viruses and the Evolution of Life written by Luis P. Villarreal and published by Amer Society for Microbiology. This book was released on 2005 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses and the Evolution of Life is an intriguing presentation of the virus–host relationship, as revealed through an examination of host evolution. This new volume avails the informed reader of a new perspective on the evolution of life while targeting the expert reader with discussions of specific scientific literature. Addresses the adaptation and evolution of viruses and, more importantly, the role of viruses in evolutionary biology Develops integrated themes for study of virology Contributes valuable information to the understanding of the virus–host relationship Integrates the relationship between genetic parasites found in host genomes with the virology of the host Communicates basic principles to the informed reader while presenting a scholarly evaluation of literature to challenge the specialist Written by one of the foremost experts in the field
Book Synopsis Virus as Populations by : Esteban Domingo
Download or read book Virus as Populations written by Esteban Domingo and published by Academic Press. This book was released on 2019-11-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. - Features current views on key steps in the origin of life and origins of viruses - Includes examples relating ancestral features of viruses with their current adaptive capacity - Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read - Considers quasispecies as a framework to understand virus adaptability and disease processes
Book Synopsis Virus Evolution by : Scott C. Weaver
Download or read book Virus Evolution written by Scott C. Weaver and published by Caister Academic Press Limited. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of virus evolution has developed during the past three decades, from one considered by many to be esoteric and unimportant for human and agricultural health, to a major driver of our thinking about infectious diseases of plants and animals. The field has been spurred on during the past 30 years by emerging viral diseases such as HIV/AIDS, hantaviruses, SARS, MERS, and Ebola, along with discoveries of the quasispecies nature and potential for rapid evolution and diversification of RNA virus populations. Over time, the focus of research has expanded and developed to encompass a diverse mixture of approaches, from highly theoretical and mechanistic studies of the basic evolutionary mechanisms to detailed research on the molecular host range, as well as virulence changes responsible for emerging viral diseases. This timely book addresses a wide range of current questions and research approaches at the forefront of the field and highlights recent advances in the understanding of the history and mechanisms of virus evolution. Wherever possible, the book's contributors have integrated information from the study of plant, animal, and bacterial viruses. Every effort has been made to unify findings and to highlight the diversity in patterns and modes of virus evolution between systems in order to aid comparative analysis. The book will be essential reading for everyone working on virus evolution and emerging viral diseases. It is also recommended for anyone working in the area of viral pathogenesis. [Subject: Microbiology, Virology, Life Science]
Download or read book Viruses written by Michael G. Cordingley and published by Harvard University Press. This book was released on 2017-06-19 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: While viruses—the world’s most abundant biological entities—are not technically alive, they invade, replicate, and evolve within living cells. Michael Cordingley goes beyond our familiarity with infections to show how viruses spur evolutionary change in their hosts and shape global ecosystems, from ocean photosynthesis to drug-resistant bacteria.
Book Synopsis The Evolution and Emergence of RNA Viruses by : Edward C. Holmes
Download or read book The Evolution and Emergence of RNA Viruses written by Edward C. Holmes and published by Oxford University Press. This book was released on 2009-06-25 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the study of viral evolution has developed rapidly in the last 30 years, little attention has been directed toward linking the mechanisms of viral evolution to the epidemiological outcomes of these processes. This book intends to fill this gap by considering the patterns and processes of viral evolution at all its spatial and temporal scales.
Book Synopsis Immunology and Evolution of Infectious Disease by : Steven A. Frank
Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Book Synopsis Antiviral Drug Resistance by : Douglas D. Richman
Download or read book Antiviral Drug Resistance written by Douglas D. Richman and published by Wiley. This book was released on 1996-12-02 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of antiviral drug resistance has provided important insights into the structure of virus enzymes, the functions of certain genes, mechanisms of action of antiviral drugs, the design of new antiviral compounds and the pathogenesis of viral diseases. The emergence of resistant strains must be explored at all stages of drug development: during the preclinical evaluation of candidate compounds; during the early clinical evaluation of new drugs; and as part of epidemiological surveillance for the prevalence of resistance during use of approved treatments. Accumulating understanding of antiviral drug resistance thus reflects progress in the chemotherapy of viral infection. Antiviral Drug Resistance provides state-of-the-art coverage of the basic and clinical aspects of this subject. It deals with the basic science, including the mechanisms of drug resistance and drug action, genetics of drug resistance, cross resistance, and X-ray crystallographic structural aspects of resistance, as well as the clinical aspects, including issues of assay of susceptibility of clinical isolates, descriptive aspects of emergence of reduced susceptibility, and clinical significance and impact of resistance. As such this unique volume will be essential to basic researchers in drug discovery and viral pathogenesis, as well as clinicians involved in antiviral chemotherapy.
Book Synopsis The New Evolution Diet by : Arthur De Vany
Download or read book The New Evolution Diet written by Arthur De Vany and published by Rodale. This book was released on 2010-12-21 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifies the dietary and lifestyle behaviors of the Paleolithic era while arguing that many common diseases, including aging, can be avoided, explaining the benefits of such principles as eating strategically, exercising periodically, and skipping meals.
Download or read book Virolution written by Frank Ryan and published by HarperCollins UK. This book was released on 2013-11-28 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The extraordinary role of viruses in evolution and how this is revolutionising biology and medicine.
Book Synopsis Experimental Evolution by : Theodore Garland
Download or read book Experimental Evolution written by Theodore Garland and published by Univ of California Press. This book was released on 2009-12-03 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes studies in experimental evolution, outlining current techniques and applications, and presenting the field's range of research.
Book Synopsis Mathematical Epidemiology of Infectious Diseases by : O. Diekmann
Download or read book Mathematical Epidemiology of Infectious Diseases written by O. Diekmann and published by John Wiley & Sons. This book was released on 2000-04-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Epidemiology of Infectious Diseases Model Building, Analysis and Interpretation O. Diekmann University of Utrecht, The Netherlands J. A. P. Heesterbeek Centre for Biometry Wageningen, The Netherlands The mathematical modelling of epidemics in populations is a vast and important area of study. It is about translating biological assumptions into mathematics, about mathematical analysis aided by interpretation and about obtaining insight into epidemic phenomena when translating mathematical results back into population biology. Model assumptions are formulated in terms of, usually stochastic, behaviour of individuals and then the resulting phenomena, at the population level, are unravelled. Conceptual clarity is attained, assumptions are stated clearly, hidden working hypotheses are attained and mechanistic links between different observables are exposed. Features: * Model construction, analysis and interpretation receive detailed attention * Uniquely covers both deterministic and stochastic viewpoints * Examples of applications given throughout * Extensive coverage of the latest research into the mathematical modelling of epidemics of infectious diseases * Provides a solid foundation of modelling skills The reader will learn to translate, model, analyse and interpret, with the help of the numerous exercises. In literally working through this text, the reader acquires modelling skills that are also valuable outside of epidemiology, certainly within population dynamics, but even beyond that. In addition, the reader receives training in mathematical argumentation. The text is aimed at applied mathematicians with an interest in population biology and epidemiology, at theoretical biologists and epidemiologists. Previous exposure to epidemic concepts is not required, as all background information is given. The book is primarily aimed at self-study and ideally suited for small discussion groups, or for use as a course text.
