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Vascular Mechanisms In Cns Trauma
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Book Synopsis Vascular Mechanisms in CNS Trauma by : Eng H. Lo
Download or read book Vascular Mechanisms in CNS Trauma written by Eng H. Lo and published by Springer Science & Business Media. This book was released on 2013-11-04 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there are a number of books on the market that deal with neuronal mechanisms and targets, the proposed book will be the only one to cover the vascular aspects of CNS trauma. The contributing authors will present basic mechanisms, explain cutting-edge experimental models and techniques, and provide several clinical chapters that provide treating physicians with some insight on the cases that they see in the ICU. The table of contents is diverse and comprehensive with chapters on molecular mechanisms, physiology, pharmacology, stem cells, genomics and proteomics, in vivo MRI and PET, as well as the clinical management of vascular parameters.
Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy
Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
Book Synopsis Central Nervous System Trauma by : S. Tsuyoshi Ohnishi
Download or read book Central Nervous System Trauma written by S. Tsuyoshi Ohnishi and published by CRC Press. This book was released on 1995-07-27 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Central nervous system trauma, which encompasses stroke, subarachnoid hemorrhage, head injury, and spinal cord injury, is a leading cause of death in developed countries. In the search for underlying mechanisms, membrane involvement has been the common link. This fourth volume in the Membrane-Linked Diseases series is therefore dedicated to research on CNS trauma. Focusing on the mechanism of membrane damage, Central Nervous System Trauma: Research Techniques presents a variety of experimental techniques to study the mechanism of CNS trauma. Animal and tissue culture models provide the bulk of the research findings in this area. Possible pharmacological interventions are analyzed. This volume offers numerous illustrative examples, including full color figures. This book serves as a valuable resource for students and researchers, assisting in the comprehension of current trends in CNS trauma and helping to stimulate the discovery of new research areas.
Book Synopsis Immunological Mechanisms and Therapies in Brain Injuries and Stroke by : Jun Chen
Download or read book Immunological Mechanisms and Therapies in Brain Injuries and Stroke written by Jun Chen and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.
Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler
Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Book Synopsis Cerebral Blood Flow, Metabolism, and Head Trauma by : Christian W. Kreipke
Download or read book Cerebral Blood Flow, Metabolism, and Head Trauma written by Christian W. Kreipke and published by Springer Science & Business Media. This book was released on 2012-08-07 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written to satisfy a wide audience, from basic scientist to clinical researcher, this volume explores such varied concepts as: the influence of CBF in the pathotrajectory of TBI, modeling TBI as a means to understand underlying pathological states associated with brain injury victims, disrupted vasculature following head trauma and advanced imaging techniques, vasoreactive substances underlying disrupted blood flow, the role of age and sex on injury outcome, and the latest pre-clinical rationale for focusing on CBF and strategies to improve blood flow as a means to improve outcome in patients suffering the effects of TBI.
Book Synopsis The Vegetative State by : Bryan Jennett
Download or read book The Vegetative State written by Bryan Jennett and published by Cambridge University Press. This book was released on 2002-02-28 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A survey of the medical, ethical and legal issues that surround this controversial topic.
Book Synopsis Nutrition and Traumatic Brain Injury by : Institute of Medicine
Download or read book Nutrition and Traumatic Brain Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.
Book Synopsis Core Topics in Neuroanaesthesia and Neurointensive Care by : Basil F. Matta
Download or read book Core Topics in Neuroanaesthesia and Neurointensive Care written by Basil F. Matta and published by Cambridge University Press. This book was released on 2011-10-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Core Topics in Neuroanesthesia and Neurointensive Care is an authoritative and practical clinical text that offers clear diagnostic and management guidance for a wide range of neuroanesthesia and neurocritical care problems. With coverage of every aspect of the discipline by outstanding world experts, this should be the first book to which practitioners turn for easily accessible and definitive advice. Initial sections cover relevant anatomy, physiology and pharmacology, intraoperative and critical care monitoring and neuroimaging. These are followed by detailed sections covering all aspects of neuroanesthesia and neurointensive care in both adult and pediatric patients. The final chapter discusses ethical and legal issues. Each chapter delivers a state-of-the art review of clinical practice, including outcome data when available. Enhanced throughout with numerous clinical photographs and line drawings, this practical and accessible text is key reading for trainee and consultant anesthetists and critical care specialists.
Book Synopsis Innate Tolerance in the CNS by : Jeffrey M. Gidday
Download or read book Innate Tolerance in the CNS written by Jeffrey M. Gidday and published by Springer Science & Business Media. This book was released on 2012-09-21 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral preconditioning is a phenomenon wherein a mild insult or stress induces cellular and tissue adaptation or tolerance to a later, severe injury, therefore reflecting the efficacy of endogenous mechanisms of cerebrovascular protection. Initially identified for rapid cardiac protection, preconditioning has expanded to all aspects of CNS protection from ischemia, trauma and potentially neurodegeneration. Many different stimuli or stressors have been identified as preconditioning agents, suggesting a downstream convergence of mechanisms and underscoring the potential for translational application of preconditioning in the clinic. Moreover, the fundamental mechanisms responsible for preconditioning-induced tolerance will help in the design novel pharmacological approaches for neuroprotection. While stroke and many other brain injuries are not predictable, in some populations (e.g., metabolic syndrome, patients undergoing carotid endarterectomy, aneurysm clipping, or with recent TIAs) the risk for stroke is identifiable and significant, and preconditioning may represent a useful strategy for neuroprotection. For unpredictable injuries, post-conditioning the brain – or inducing endogenous protective mechanisms after the initial injury – can also abrogate the extent of injury. Finally, remote pre- and post-conditioning methods have been developed in animals, and are now being tested in clinical trials, wherein a brief, noninjurious stress to a noncerebral tissue (i.e., skeletal muscle) can provide protection to the CNS and thereby allows clinicians the opportunity to circumvent concerns regarding the direct preconditioning of neurological tissues.
Book Synopsis Imaging Acute Neurologic Disease by : Massimo Filippi
Download or read book Imaging Acute Neurologic Disease written by Massimo Filippi and published by Cambridge University Press. This book was released on 2014-09-11 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of best practice in using diagnostic imaging in acute neurologic conditions. The symptom-based approach guides the choice of the available imaging tools for efficient, accurate, and cost-effective diagnosis. Effective examination algorithms integrate neurological and imaging concepts with the practical demands and constraints of emergency care.
Book Synopsis The Neurobiology of Central Nervous System Trauma by : Steven K. Salzman
Download or read book The Neurobiology of Central Nervous System Trauma written by Steven K. Salzman and published by . This book was released on 1994 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a reference text in the field of experimental traumatology. Chapters are written by the recognized leaders in each area. The first section covers methodological considerations, including discussion of in vitro and in vivo models; metabolic and hemodynamic factors; anatomical and electrophysiological correlates; and behavioral evaluation. The second section discusses pathophysiological factors including ischemia, ionic changes, immune-inflammatory responses, neurotransmitter/neuromodulatory alterations, effects of lipid metabolism, astroglial responses and molecular mechanisms. The final section reviews treatments including experimental pharmacology, growth factors, regeneration, transplantation and clinical treatment. This book is invaluable to researchers as well as clinicians involved in head or spinal cord injury.
Download or read book Neurotrauma written by Raj K. Narayan and published by McGraw-Hill. This book was released on 1996 with total page 1558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a comprehensive work in the field of neurotrauma and critical care. It incorporates the fields of head injury, spinal injury and basic neurotrauma research into one source. The major emphasis is on the treatment of patients with head and spinal cord injury, including the management of all other problems that bear upon the care of these patients.
Book Synopsis Mechanisms of Neuroinflammation and Inflammatory Neurodegeneration in Acute Brain Injury by : Arthur Liesz
Download or read book Mechanisms of Neuroinflammation and Inflammatory Neurodegeneration in Acute Brain Injury written by Arthur Liesz and published by Frontiers Media SA. This book was released on 2015-11-13 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of brain-immune interactions became a cutting-edge topic in systemic neurosciences over the past years. Acute lesions of the brain parenchyma, particularly, induce a profound and highly complex neuroinflammatory reaction with similar mechanistic properties between differing disease paradigms like ischemic stroke, intracerebral hemorrhage (ICH) and traumatic brain injury (TBI). Resident microglial cells sense tissue damage and initiate inflammation, activation of the endothelial brain-immune interface promotes recruitment of systemic immune cells to the brain and systemic humoral immune mediators (e.g. complements and cytokines) enter the brain through the damaged blood-brain barrier. These cellular and humoral constituents of the neuroinflammatory reaction to brain injury contribute substantially to secondary brain damage and neurodegeneration. Diverse inflammatory cascades such as pro-inflammatory cytokine secretion of invading leukocytes and direct cell-cell-contact cytotoxicity between lymphocytes and neurons have been demonstrated to mediate the inflammatory ‘collateral damage’ in models of acute brain injury. Besides mediating neuronal cell loss and degeneration, secondary inflammatory mechanisms also contribute to functional modulation of neurons and the impact of post-lesional neuroinflammation can even be detected on the behavioral level. The contribution of several specific immune cell subpopulations to the complex orchestration of secondary neuroinflammation has been revealed just recently. However, the differential vulnerability of specific neuronal cell types and the molecular mechanisms of inflammatory neurodegeneration are still elusive. Furthermore, we are only on the verge of characterizing the control of long-term recovery and neuronal plasticity after brain damage by inflammatory pathways. Yet, a more detailed but also comprehensive understanding of the multifaceted interaction of these two supersystems is of direct translational relevance. Immunotherapeutic strategies currently shift to the center of translational research in acute CNS lesion since all clinical trials investigating direct neuroprotective therapies failed. To advance our knowledge on brain-immune communications after brain damage an interdisciplinary approach covered by cellular neuroscience as well as neuroimmunology, brain imaging and behavioral sciences is crucial to thoroughly depict the intricate mechanisms.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309486890 Total Pages :211 pages Book Rating :4.3/5 (94 download)
Book Synopsis Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans by : National Academies of Sciences, Engineering, and Medicine
Download or read book Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-05-20 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Veterans Benefits Administration (VBA) provides disability compensation to veterans with a service-connected injury, and to receive disability compensation from the Department of Veterans Affairs (VA), a veteran must submit a claim or have a claim submitted on his or her behalf. Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans reviews the process by which the VA assesses impairments resulting from traumatic brain injury for purposes of awarding disability compensation. This report also provides recommendations for legislative or administrative action for improving the adjudication of veterans' claims seeking entitlement to compensation for all impairments arising from a traumatic brain injury.
Book Synopsis Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care by : Arun Gupta
Download or read book Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care written by Arun Gupta and published by Cambridge University Press. This book was released on 2018-06-21 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition presents core clinical neuroanesthesia and neurointensive care knowledge in a practical, user-friendly format.
