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Author : Elvin Abraham Kabat
Publisher :
ISBN 13 :
Total Pages : 142 pages
Book Rating : 4.:/5 (319 download)
Download or read book Variable Regions of Immunoglobulin Chains written by Elvin Abraham Kabat and published by . This book was released on 1976 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Larry W. Moreland
Publisher : Springer Science & Business Media
ISBN 13 : 3540206256
Total Pages : 933 pages
Book Rating : 4.5/5 (42 download)
Download or read book Rheumatology and Immunology Therapy written by Larry W. Moreland and published by Springer Science & Business Media. This book was released on 2004-07-20 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Entries in a practical A to Z Format Highly therapy-focused Uniform and clearly arranged entries for ease of reference Comprehensive information on symptoms and therapeutical possibilities of rheumatologic and musculoskeletal diseases as well as drugs Written by leading experts in the field
Author : William R Strohl
Publisher : Elsevier
ISBN 13 : 1908818093
Total Pages : 697 pages
Book Rating : 4.9/5 (88 download)
Download or read book Therapeutic Antibody Engineering written by William R Strohl and published by Elsevier. This book was released on 2012-10-16 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering. - Goes beyond the standard engineering issues covered by most books and delves into structure-function relationships - Integration of knowledge across all areas of antibody engineering, development, and marketing - Discusses how current and future genetic engineering of cell lines will pave the way for much higher productivity
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Elvin Abraham Kabat
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (22 download)
Download or read book Variable Regions of Immunoglobulin Chains written by Elvin Abraham Kabat and published by . This book was released on 1976 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alfred I. Tauber
Publisher : Harvard University Press
ISBN 13 : 9780674001824
Total Pages : 532 pages
Book Rating : 4.0/5 (18 download)
Download or read book The Generation of Diversity written by Alfred I. Tauber and published by Harvard University Press. This book was released on 2000 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period. In recent years immunology has been one of the most exciting--and successful--fields of biomedical research; this book provides essential background for understanding the conceptual conflicts occurring in the field.
Author : Roald Nezlin
Publisher : Academic Press
ISBN 13 : 008053452X
Total Pages : 292 pages
Book Rating : 4.0/5 (85 download)
Download or read book The Immunoglobulins written by Roald Nezlin and published by Academic Press. This book was released on 1998-05-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive up-to-date information on the structure and function of immunoglobulins. It describes the basic features of these molecules, which assists the reader in understanding how they function as an integral part of the immune system. The Immunoglobulins describes the localization and structure of different binding sites of immunoglobulin molecules, including the antigen-binding site, on the basis of latest x-ray crystallography studies. It discusses recently developed biotechnological methods that allow scientists to obtain fully active antibody molecules in vitro even without immunization and to construct new variants of immunoglobulins and their fragments by fusing with various other active molecules. A survey of recent knowledge on immunoglobulin-binding molecules other than antigens and on flexibility of immunoglobulin molecules concludes the discussion of functional aspects of the problem. - Describes recent reviews on the structure and function of immunoglobulin molecules of various species - Summarizes in detail recent findings on the fine structure of the antigen-combining site - Presents comparative data on the antigen-recognizing sites of other molecules such as MHC proteins and T-cell receptors - Summarizes growing data on immunoglobulin binding sites responsible for the reaction of immunoglobulins with molecules other than antigens - Explores the rapid advance of recent biotechnological methods used for the construction of antibody molecules and their fragments with new properties - Presents extensive references and is lavishly illustrated
Author : Alfred Nisonoff
Publisher : Academic Press
ISBN 13 : 1483273857
Total Pages : 560 pages
Book Rating : 4.4/5 (832 download)
Download or read book The Antibody Molecule written by Alfred Nisonoff and published by Academic Press. This book was released on 2014-06-28 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Antibody Molecule reviews the literature leading to current knowledge of the structure of immunoglobulins. The book begins by outlining some of the basic structural characteristics of immunoglobulins without citing the references on which the information is based. Separate chapters follow covering the chemical nature of the active site of an antibody molecule and mechanisms of interaction with hapten; the general structural features and properties of the various classes of human immunoglobulin; and amino acid sequences of human and mouse L chains and of human and rabbit H chains. Subsequent chapters deal with the evolution of the immunoglobulin classes; special properties of mouse, guinea pig, rabbit, and horse immunoglobulins; idiotypic specificities of immunglobulins; and the genetic control of antibodies. This book is meant for immunologists who have not personally observed the development of this exciting period in the history of immunology. It will also provide useful supplemental reading for the serious student or investigator who wishes to become familiar with the nature of the antibody molecule, its genetic control, and mode of action.
Author : Bernd Kaspers
Publisher : Academic Press
ISBN 13 : 0123972728
Total Pages : 456 pages
Book Rating : 4.1/5 (239 download)
Download or read book Avian Immunology written by Bernd Kaspers and published by Academic Press. This book was released on 2012-12-02 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. - With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far - Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors - Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
Author : Eleftherios P. Diamandis
Publisher : Academic Press
ISBN 13 : 0080534503
Total Pages : 613 pages
Book Rating : 4.0/5 (85 download)
Download or read book Immunoassay written by Eleftherios P. Diamandis and published by Academic Press. This book was released on 1996-06-21 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunoassays are among the most powerful and sensitive technologies now available for patient diagnosis and monitoring. This book is an indispensable guide to information on the theory and practice of immunoassays. It discusses the scientific basis of these technologies in a logical, organized, and heuristic manner and provides protocols for specific assays. The contents of this unique book are balanced among theory, practical issues, quality control, automation, and subspecialty areas, making it ideal for health science students, laboratory scientists, and clinicians. - Presents up-to-date information - Provides extensive cross-referencing - Covers theory and practice in full detail - Written by leading authorities
Author : Marie-Paule Lefranc
Publisher : Academic Press
ISBN 13 : 0080574475
Total Pages : 472 pages
Book Rating : 4.0/5 (85 download)
Download or read book The Immunoglobulin FactsBook written by Marie-Paule Lefranc and published by Academic Press. This book was released on 2001-05-23 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The FactsBook series has established itself as the best source of easily accessible and accurate facts about protein groups. Books in the series use an easy-to-follow format and are meticulously researched and compiled by experts in the field.The Immunoglobulin FactsBook is the first published reference for all 203 human functional and ORF immunoglobulin genes. It is complete and standardized and employs nomenclature approved by the HUGO Nomenclature Committee.
Author : Gary Litman
Publisher : Springer Science & Business Media
ISBN 13 : 1468408054
Total Pages : 391 pages
Book Rating : 4.4/5 (684 download)
Download or read book Immunoglobulins written by Gary Litman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery more than thirty years ago that antibody actlvlty could be localized to discrete plasma protein fractions, the study of immunoglobulin struc ture and function has dominated the field of immunochemistry. During this time, sources of homogeneous immunoglobulin molecules have been discovered, the subunit nature of the proteins has been defined, and the three-dimensional struc tures of the antigen-recognition portion of several antibody molecules have been elucidated. Insights into the complicated genetic control of these proteins are being gained rapidly through analysis of amino acid sequences of naturally occurring and induced homogeneous immunoglobulins. Immunoglobulins have been analyzed by protein chemists as models of complex multimeric systems, examined by geneticists studying serum protein polymorphisms, and employed by molecular biologists as highly selective probes capable of distinguishing minor features of molecular topog raphy. Clinical applications have ranged from the now routine quantitation of immunoglobulin levels to the use of antibodies to detect trace levels of a variety of natural products and drug metabolites. All these applications have depended ulti mately on a thorough understanding of the immunoglobulin and its antigen-combin ing site. To cover the entire field of immunoglobulin structure and function would require many volumes this size; therefore, subjects presented in this volume represent those which we felt contribute most to our current understanding of this protein family. The first chapters deal with the structure and function of the immunoglobulin molecule.
Author : Richard L. Wasserman
Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.:/5 (894 download)
Download or read book Structure and Evolution of Immunoglobulin Heavy Chain Variable Regions written by Richard L. Wasserman and published by . This book was released on 1975 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : F. Calabi
Publisher : Elsevier
ISBN 13 : 0080860761
Total Pages : 261 pages
Book Rating : 4.0/5 (88 download)
Download or read book Molecular Genetics of Immunoglobulin written by F. Calabi and published by Elsevier. This book was released on 1987-12-01 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the molecular genetics of immunoglobulins has been enormously advanced by the application of recombinant DNA technology. This new volume in the popular series New Comprehensive Biochemistry contains eight chapters that draw together reviews summarising the research into immunoglobulins and the arrangement, rearrangement and expression of their gene structure.Molecular Genetics of Immunoglobulin will be of particular importance to those working in the areas of genetics and molecular biology, immunology, and cell biology.
Author : Tasuku Honjo
Publisher : Academic Press
ISBN 13 : 9780123979339
Total Pages : 0 pages
Book Rating : 4.9/5 (793 download)
Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Academic Press. This book was released on 2014-12-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
Author : Hans U. Lutz
Publisher : Springer Science & Business Media
ISBN 13 : 1461434610
Total Pages : 285 pages
Book Rating : 4.4/5 (614 download)
Download or read book Naturally Occurring Antibodies (NAbs) written by Hans U. Lutz and published by Springer Science & Business Media. This book was released on 2012-08-19 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume illustrates the functional properties of NAbs. Authors from pioneering groups report in their chapters on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. Scientists interested in the regulation and modulation of components of the immune system found a whole variety of NAbs to cytokines with regulatory and protective functions and NAbs that modulate, e.g., dendritic cells, regulatory T cells, B cells and granulocytes. Considering the large plasma pools and initial difficulties in preparing IVIG that does not induce adverse effects upon infusion into recipients, this volume ends with a historical chapter on how pooled human plasma was fractionated and the IgG component pretreated for a safe intravenous application.
Author : Gheorghita Isvoranu
Publisher : BoD – Books on Demand
ISBN 13 : 9535133438
Total Pages : 194 pages
Book Rating : 4.5/5 (351 download)
Download or read book Lymphocyte Updates written by Gheorghita Isvoranu and published by BoD – Books on Demand. This book was released on 2017-07-12 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a synergic effort of an international team of specialists in immunology to expand the scientific achievements in the field of lymphocytes. It offers important and specific updated information to researchers, students, teachers, and medical professionals. Moreover, considering the remarkable dynamics of immunology and immunotherapy, this book "Lymphocyte Updates - Cancer, Autoimmunity, and Infection" aims to represent a significant source of concise scientific data and advancement of knowledge in this field. The chapters offer new insights into the latest scientific progress on lymphocyte roles in protective immunity, as well as their involvement in pathogenesis of various disorders.
