Vaccine Cell Substrates 2004

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Vaccine Cell Substrates 2004

Author : Rebecca Sheets
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Vaccine Cell Substrates 2004 by : Rebecca Sheets

Download or read book Vaccine Cell Substrates 2004 written by Rebecca Sheets and published by S. Karger AG (Switzerland). This book was released on 2006 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication comprises the proceedings of the Vaccine Cell Substrates 2004 conference. The purpose of this conference was to review current data and progress in the field of cell substrates, discuss the continued use of existing tests and the appropriateness of new ones at this time, and develop consensus recommendations on how to address these issues, by either recommending implementation or identifying research gaps that preclude decision-making. Scientific topics covered oncogenicity of cellular components, both latent viruses and cellular DNA, viral adventitious agent test methods, level of assurance provided by the current tests, bovine (and porcine) viruses in (primarily) bovine-derived raw materials, and bovine spongiform encephalopathy agents as potential contaminants of cell substrates. Also presented were tests that ensure the safety and quality of novel vaccine cell substrates for investigational vaccine production. Academia, regulators, the vaccine industry and the testing industry developing, regulating or testing viral vaccines will greatly benefit from the wealth of new findings.

Evolving Scientific and Regulatory Perspectives on Cell Substrates for Vaccine Development

Author : Fred Brown
Publisher :
ISBN 13 :
Total Pages : 564 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Evolving Scientific and Regulatory Perspectives on Cell Substrates for Vaccine Development by : Fred Brown

Download or read book Evolving Scientific and Regulatory Perspectives on Cell Substrates for Vaccine Development written by Fred Brown and published by . This book was released on 2001 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: In September 1999, the cell substrate workshop entitled 'Evolution of Cell Substrates Used in the Manufacture of Biologicals' was held as a means to consider in depth the issues raised by the need to use neoplastic, i.e. continuous, cells as substrates for viral vaccine manufacture. Workshop goals included identifying the risks and concerns associated with the use of neoplastic cell substrates and determining the manner in which these could be assessed. Volume 106 of Developments in Biologicals presents the edited proceedings of this workshop. It is the latest in a series of monographs that go back to 1967 and record the proceedings of meetings devoted to issues concerning the use of cells cultured in vitro as substrates for the manufacture of viral vaccines. The current workshop covered the following: - a review of the history of cell substrate use in the production of biologicals - scientific issues related to the development of the neoplastic state and tumorigenicity - viral-viral and viral-cell interactions - the oncogenic potential of residual cell-substrate DNA - adventitious agent testing - ways to generate immortalized cells in vitro The purpose of these discussions was to build on the concepts and precedents for the scientifically based, regulatory management of viral vaccines documented in the earlier monographs. It is the hope of the meeting organizers and sponsors that this volume will assist in generating confidence among vaccine developers, manufacturers, regulatory agencies and the general public that the use of neoplastic cell substrates, within an effective, reasoned, regulatory approach, is feasible.

Vaccine Cell Substrates 2004

Author : Rebecca Sheets
Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805579995
Total Pages : 380 pages
Book Rating : 4.5/5 (799 download)

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Book Synopsis Vaccine Cell Substrates 2004 by : Rebecca Sheets

THE STANDARDIZATION OF CELL SUBSTRATES FOR THE PRODUCTION OF VIRUS VACCINES- PROCEEDINGS OF THE 62ND JOINT WHO

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (846 download)

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Book Synopsis THE STANDARDIZATION OF CELL SUBSTRATES FOR THE PRODUCTION OF VIRUS VACCINES- PROCEEDINGS OF THE 62ND JOINT WHO by :

Download or read book THE STANDARDIZATION OF CELL SUBSTRATES FOR THE PRODUCTION OF VIRUS VACCINES- PROCEEDINGS OF THE 62ND JOINT WHO written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transcript of Proceedings

Author : National Institute of Allergy and Infectious Diseases (U.S.)
Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.:/5 (143 download)

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Book Synopsis Transcript of Proceedings by : National Institute of Allergy and Infectious Diseases (U.S.)

Download or read book Transcript of Proceedings written by National Institute of Allergy and Infectious Diseases (U.S.) and published by . This book was released on 1976 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Industrial Scale Suspension Culture of Living Cells

Author : Hans-Peter Meyer
Publisher : John Wiley & Sons
ISBN 13 : 3527335471
Total Pages : 642 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Industrial Scale Suspension Culture of Living Cells by : Hans-Peter Meyer

Download or read book Industrial Scale Suspension Culture of Living Cells written by Hans-Peter Meyer and published by John Wiley & Sons. This book was released on 2014-08-04 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: The submersed cultivation of organisms in sterile containments or fermenters has become the standard manufacturing procedure, and will remain the gold standard for some time to come. This book thus addresses submersed cell culture and fermentation and its importance for the manufacturing industry. It goes beyond expression systems and integrally investigates all those factors relevant for manufacturing using suspension cultures. In so doing, the contributions cover all industrial cultivation methods in a comprehensive and comparative manner, with most of the authors coming from the industry itself. Depending on the maturity of the technology, the chapters address in turn the expression system, basic process design, key factors affecting process economics, plant and bioreactor design, and regulatory aspects.

Biological Safety

Author : Dawn P. Wooley
Publisher : John Wiley & Sons
ISBN 13 : 155581963X
Total Pages : 300 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Biological Safety by : Dawn P. Wooley

Download or read book Biological Safety written by Dawn P. Wooley and published by John Wiley & Sons. This book was released on 2020-07-02 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.

Vaccines and Diagnostics for Transboundary Animal Diseases

Author : J.A. Roth
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318023663
Total Pages : 231 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Vaccines and Diagnostics for Transboundary Animal Diseases by : J.A. Roth

Download or read book Vaccines and Diagnostics for Transboundary Animal Diseases written by J.A. Roth and published by Karger Medical and Scientific Publishers. This book was released on 2013-04-18 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transboundary animal diseases (TADs) are a major threat to livestock. They are highly contagious or transmissible, and they have the potential to cause high morbidity and mortality in both susceptible animal populations and humans. In addition, not only are TADs detrimental to national economies, they are also a serious threat to world food security. This volume presents the proceedings of an international workshop on Vaccines and Diagnostics for Transboundary Animal Diseases that was held in Ames (Iowa, USA) in 2012. Experts and scientists from academia, industry and government reviewed the current status of vaccines and diagnostics for high priority TADs, decision-making and regulatory processes for veterinary biologics, and the roles and responsibilities of government agencies. The discussions also addressed achievements and gaps in vaccine and diagnostics development for 11 important TADs as well as the translation of research findings into licensed novel vaccines and diagnostics for high-priority TADs.

The Virus and the Vaccine

Author : Debbie Bookchin
Publisher : Macmillan + ORM
ISBN 13 : 1466848995
Total Pages : 541 pages
Book Rating : 4.4/5 (668 download)

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Book Synopsis The Virus and the Vaccine by : Debbie Bookchin

Download or read book The Virus and the Vaccine written by Debbie Bookchin and published by Macmillan + ORM. This book was released on 2013-07-02 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jonas Salk's polio vaccine has taken on an almost legendary quality as a medical miracle, for it largely eradicated one of the most feared diseases of the 20th century. But the story of the vaccine has a dark side, one that has never been fully told before... Between 1954 and 1963, close to 98 million Americans received polio vaccinations contaminated with a carcinogenic monkey virus, now known as SV40. A concerted government effort downplayed the incident, and it was generally accepted that although oncogenic to laboratory animals, SV40 was harmless to humans. But now SV40 in showing up in human cancers, and prominent researchers are demanding a serious public health response to this forgotten polio vaccine contaminant. A gripping medical detective story, The Virus and the Vaccine raises major questions about vaccine policy.

Vaccines

Author : Stanley A. Plotkin
Publisher : Elsevier Health Sciences
ISBN 13 : 1437721583
Total Pages : 1748 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Vaccines by : Stanley A. Plotkin

Download or read book Vaccines written by Stanley A. Plotkin and published by Elsevier Health Sciences. This book was released on 2008-02-11 with total page 1748 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety...recommendations for vaccine use, with rationales...data on the impact of vaccination programs on morbidity and mortality...and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage. Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies. Analyses the cost-benefit and cost-effectiveness of vaccines. Discusses the proper use of immune globulins and antitoxins. Illustrates concepts and objective data with approximately 600 tables and figures. Includes access to a companion web site offering the complete contents of the book - fully searchable - for rapid consultation from anyplace with an Internet connection.

Animal Genomics for Animal Health

Author : Marie-Hélène Pinard
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805586191
Total Pages : 455 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Animal Genomics for Animal Health by : Marie-Hélène Pinard

Download or read book Animal Genomics for Animal Health written by Marie-Hélène Pinard and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: "It includes a review of the state of the art in animal genomics and its applications to animal health. The contributions describe the new tools available, such as HapMaps for chicken and cattle, and show how the understanding of gene structure and function can be successfully applied to delineate the molecular mechanisms of disease and determine complex phenotypes associated with health traits. A critical evaluation of future needs and future applications of animal genomics is also presented. The integration of animal genomics in animal health research is likely to revolutionize the way scientists approach the challenges of discovering highly effective drugs and vaccines for animal diseases."--BOOK JACKET.

New Diagnostic Technology

Author : Philippe Vannier
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis New Diagnostic Technology by : Philippe Vannier

Download or read book New Diagnostic Technology written by Philippe Vannier and published by S. Karger AG (Switzerland). This book was released on 2006 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological advances have resulted in the development of several new biochemistry-based test procedures such as DNA micro-arrays, rapid sequencing and multiple applications of polymerase chain reaction. The limitations of such tests and the problems of standardization and validation related to their use for the detection of agents and toxins, diagnosis of human and animal diseases, and quality control of human and veterinary biological products must be considered. Practical examples of the use of these new technologies, but also the difficulties, limits and uncertainties encountered in their application need to be shared. This volume presents the proceedings of a conference in Saint-Malo, France, held to facilitate discussion between government authorities, industry, scientists and other users of these new techniques. Information on the principles of these novel methods, the need for standardization and validation, applications in diagnosis and surveillance, certainties and uncertainties in agent or toxin identification as well as examples of quality control of human and veterinary biological products were addressed. Conclusions and recommendations concerning the development and standardization of these new technologies were developed by the participants and are published in these proceedings. Professionals involved in biological standardization, diagnosis, and human and animal health programs should find this to be a very valuable book.

Vaccination

Author : Betty Dodet
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Vaccination by : Betty Dodet

Download or read book Vaccination written by Betty Dodet and published by S. Karger AG (Switzerland). This book was released on 2007 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The international community is confronted with a crisis caused by the unprecedented global spread of highly pathogenic avian influenza and its consequent scientific, economic, political, social and ethical challenges. Control strategies based only on the application of sanitary measures and the culling of animals that are infected or suspected of being infected have proven insufficient to avoid the propagation of infection. The OIE, together with the FAO, recommend the strategic use of poultry vaccination in certain situations as part of an overall integrated strategy to control the disease. This volume presents the proceedings of a scientific conference co-organized by the OIE, FAO and the Istituto Zooprofilattico Sperimentale delle Venezie with the support of the European Commission. The conference brought together scientists, representatives of government authorities, industry and other stakeholders to review current methods and recent experiences in the use of vaccination as a means to control and prevent losses due to avian influenza. They also scrutinized international standards and regulations for vaccination and considered the implementation of vaccination programmes. The proceedings include presentations on the experiences made in various parts of the world and the challenges and constraints faced by developing countries in implementing effective vaccination campaigns. Other contributions provide guidance to decision makers concerned with planning vaccination campaigns and up-to-date information on developments in avian influenza vaccines, their efficacy, their performance in different avian species and on strategies of differentiating infected from vaccinated animals as well as their application.

History of Vaccine Development

Author : Stanley A. Plotkin
Publisher : Springer Science & Business Media
ISBN 13 : 1441913394
Total Pages : 352 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis History of Vaccine Development by : Stanley A. Plotkin

Download or read book History of Vaccine Development written by Stanley A. Plotkin and published by Springer Science & Business Media. This book was released on 2011-05-11 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.

Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention

Author : Charles Edward Rupprecht
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention by : Charles Edward Rupprecht

Download or read book Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention written by Charles Edward Rupprecht and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Veterinary Vaccines

Author : Samia Metwally
Publisher : John Wiley & Sons
ISBN 13 : 1119506263
Total Pages : 350 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Veterinary Vaccines by : Samia Metwally

Download or read book Veterinary Vaccines written by Samia Metwally and published by John Wiley & Sons. This book was released on 2021-04-01 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a concise and authoritative reference on the use of vaccines against diseases of livestock Compiled by Senior Animal Health Officers at The Food and Agriculture Organization of the United Nations, and with contributions from international leading experts, Veterinary Vaccines: Principles and Applications is a concise and authoritative reference featuring easily readable reviews of the latest research in vaccinology and vaccine immune response to pathogens of major economic impact to livestock. It covers advice and recommendations for vaccine production, quality control, and effective vaccination schemes including vaccine selection, specifications, vaccination programs, vaccine handling in the field, application, failures, and assessment of herd protection. In addition, the book presents discussions on the current status and potential future developments of vaccines and vaccination against selected transboundary animal diseases. Provides a clear and comprehensive guide on using veterinary vaccines to protect livestock from diseases Teaches the principles of vaccinology and vaccine immune response Highlights the vaccine production schemes and standards for quality control testing Offers easy-to-read reviews of the most current research on the subject Gives readers advice and recommendations on which vaccination schemes are most effective Discusses the today’s state of vaccines and vaccination against selected transboundary animal diseases as well as possible future developments in the field Veterinary Vaccines: Principles and Applications is an important resource for veterinary practitioners, animal health department officials, vaccine scientists, and veterinary students. It will also be of interest to professional associations and NGO active in livestock industry.

The Flaviviruses: Detection, Diagnosis and Vaccine Development

Author :
Publisher : Elsevier
ISBN 13 : 0080493831
Total Pages : 607 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Flaviviruses: Detection, Diagnosis and Vaccine Development by :

Download or read book The Flaviviruses: Detection, Diagnosis and Vaccine Development written by and published by Elsevier. This book was released on 2003-12-18 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research. - Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions - Descibes the technologies that have contributed to our current knowledge about the Flaviviruses - Identifies the major problems faced in understanding the virus-host interactins that result in disease - An exhaustive compendium of current and past knowledge on the Flavivirus family