Electric Cell-Substrate Impedance Sensing and Cancer Metastasis

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Publisher : Springer Science & Business Media
ISBN 13 : 9400749279
Total Pages : 261 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Electric Cell-Substrate Impedance Sensing and Cancer Metastasis by : Wen G. Jiang

Download or read book Electric Cell-Substrate Impedance Sensing and Cancer Metastasis written by Wen G. Jiang and published by Springer Science & Business Media. This book was released on 2012-09-14 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell based impedance sensing is becoming a new biophysical and cellular technology in cell based analyses. The technology has been used in investigation of cellular growth and death, cell adhesion and migration, cell invasion and cell-cell interactions, cell toxicity, angiogenesis, cell permeability, signal transduction and cellular behaviour under flow conditions. It is a probe free, highly sensitive, and versatile technology platform. Recent development in the technology has also allowed high throughput, automated analyses. It has been widely explored in chemistry, toxicity, cell biology, cancer biology, and other areas of chemistry, medicinal chemistry, life and medical science. Written by experts in the area of cell impedance sensing, including the Nobel Laureate Dr Ivar Giaever, this books covers the background of electric cell-substrate impedance sensing, their applications in cell based investigations, particularly in the area of cancer biology. This book is the first on this technology platform and will be a highly useful reference for molecular and cell biologists, cancer biologists, chemists and biochemists, clinical researchers who work in the areas of cell biology, molecular biology, toxicology, pharmaceutical industry, life science and medical research.

Dissertation Abstracts International

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Publisher :
ISBN 13 :
Total Pages : 800 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2008 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Surface and Interfacial Aspects of Cell Adhesion

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Publisher : CRC Press
ISBN 13 : 9004190783
Total Pages : 545 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Surface and Interfacial Aspects of Cell Adhesion by : Alain Carré

Download or read book Surface and Interfacial Aspects of Cell Adhesion written by Alain Carré and published by CRC Press. This book was released on 2011-01-19 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell adhesion comes into play in almost all domains of life. The range of situations in which it occurs, involving organisms, living tissues, microorganisms or single cells, is endless. Cell adhesion is involved in the binding of a cell to a surface, extracellular matrix, or another cell using cell adhesion molecules. It is crucial in the formation and maintenance of coherent multicellular structures. Cell surface adhesion molecules (integrins, for example) which transmit information from the extracellular matrix to the cell play vital roles in numerous cellular processes. Some of these include: cell growth, differentiation, embryogenesis, immune cell transmigration and response, and cancer metastasis. Also cell adhesion is involved in most of pathological situations. This book is divided into four parts as follows: Part 1: Fundamentals of Cell Adhesion; Part 2: Methods to Study Cell Adhesion; Part 3: Surface Treatments to Control Cell Adhesion and Behavior; and Part 4: Cell Adhesion in Medicine and Therapy. A bountiful information is covered in this book which represents the cumulative wisdom of many world-renowned researchers( physicists, materials scientists, chemists and biologists) engaged in unraveling the mechanisms of cell adhesion and how to mitigate or control it. It quite patent from the topics covered in this book that the subject of cell adhesion is truly interdisciplinary. This book should be of great interest and value to anyone interested in cell adhesion which is vitally important to human life.

Electroporation and Electrofusion in Cell Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 1489925287
Total Pages : 435 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Electroporation and Electrofusion in Cell Biology by : C.A. Jordan

Download or read book Electroporation and Electrofusion in Cell Biology written by C.A. Jordan and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells can be funny. Try to grow them with a slightly wrong recipe, and they turn over and die. But hit them with an electric field strong enough to knock over a horse, and they do enough things to justify international meetings, to fill a sizable book, and to lead one to speak of an entirely new technology for cell manipulation. The very improbability of these events not only raises questions about why things happen but also leads to a long list of practical systems in which the application of strong electric fields might enable the merger of cell contents or the introduction of alien but vital material. Inevitably, the basic questions and the practical applications will not keep in step. The questions are intrinsically tough. It is hard enough to analyze the action of the relatively weak fields that rotate or align cells, but it is nearly impossible to predict responses to the cell-shredding bursts of electricity that cause them to fuse or to open up to very large molecular assemblies. Even so, theoretical studies and systematic examination of model systems have produced some creditable results, ideas which should ultimately provide hints of what to try next.

Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors

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Author :
Publisher : Springer
ISBN 13 : 331945384X
Total Pages : 391 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors by : Maximilian Oberleitner

Download or read book Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors written by Maximilian Oberleitner and published by Springer. This book was released on 2017-09-26 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis describes novel substrate embedded physical sensors that can be used to monitor different types of cell-based assays non-invasively and label-free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedical research. The author, Maximilian Oberleitner, describes approaches in which the cells are directly grown on different sensor surfaces (gold-film electrodes, shear wave resonators or dye-doped polymer films). This approach, with the reacting cells in particularly close proximity and contact with the sensor surface, is key to a remarkable sensitivity, opening the way for a variety of new applications. This thesis not only introduces the fundamentals of each approach, but it also describes in great detail the design principles and elucidates the boundary conditions of the new sensors.

Cell-based Biosensors

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Publisher : Artech House
ISBN 13 : 1596934409
Total Pages : 291 pages
Book Rating : 4.5/5 (969 download)

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Book Synopsis Cell-based Biosensors by : Qingjun Liu

Download or read book Cell-based Biosensors written by Qingjun Liu and published by Artech House. This book was released on 2009-10 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by recognized experts the field, this leading-edge resource is the first book to systematically introduce the concept, technology, and development of cell-based biosensors. You find details on the latest cell-based biosensor models and novel micro-structure biosensor techniques. Taking an interdisciplinary approach, this unique volume presents the latest innovative applications of cell-based biosensors in a variety of biomedical fields. The book also explores future trends of cell-based biosensors, including integrated chips, nanotechnology and microfluidics. Over 140 illustrations help clarify key topics throughout the book.

Angiogenesis Assays

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Publisher : John Wiley & Sons
ISBN 13 : 047002934X
Total Pages : 410 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Angiogenesis Assays by : Carolyn A. Staton

Download or read book Angiogenesis Assays written by Carolyn A. Staton and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.

Electrochemistry

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Publisher : Oxford University Press on Demand
ISBN 13 : 9780198553885
Total Pages : 427 pages
Book Rating : 4.5/5 (538 download)

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Book Synopsis Electrochemistry by : Christopher M. A. Brett

Download or read book Electrochemistry written by Christopher M. A. Brett and published by Oxford University Press on Demand. This book was released on 1993 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book describes modern electrochemistry, from fundamental principles to the methods that can be used to study electrode and electrochemical processes, and finally, at the wide-ranging applications in sensors, industry, corrosion, and bioelectrochemistry. The breadth of coverage ensures that this volume will be valuable not only to undergraduate and graduate students, but also to research workers.

Bioimpedance in Biomedical Applications and Research

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Publisher : Springer
ISBN 13 : 3319743880
Total Pages : 288 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Bioimpedance in Biomedical Applications and Research by : Franco Simini

Download or read book Bioimpedance in Biomedical Applications and Research written by Franco Simini and published by Springer. This book was released on 2018-03-16 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the best contributions to the advancement of bioimpedance knowledge and use from the Latin American Congress series, CLABIO. Basic bioimpedance facts as well as promising and original contributions to bioimpedance theory and applications are presented, giving the reader stimulating material for reflection, decision making, and further experiments. Contributions come from a diverse international pool of experts and address topics on electrode and skin impedance modelling, tomography, spectroscopy, instrumentation, and clinical applications.

Cell Analysis on Microfluidics

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Publisher : Springer
ISBN 13 : 9811053944
Total Pages : 435 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Cell Analysis on Microfluidics by : Jin-Ming Lin

Download or read book Cell Analysis on Microfluidics written by Jin-Ming Lin and published by Springer. This book was released on 2017-10-25 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.

A Current Integrator

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Publisher :
ISBN 13 :
Total Pages : 6 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Current Integrator by : H. T. Gittings

Download or read book A Current Integrator written by H. T. Gittings and published by . This book was released on 1948 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt:

3D Electro-Rotation of Single Cells

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Publisher : Springer Nature
ISBN 13 : 3031016661
Total Pages : 101 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis 3D Electro-Rotation of Single Cells by : Liang Huang

Download or read book 3D Electro-Rotation of Single Cells written by Liang Huang and published by Springer Nature. This book was released on 2022-05-31 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dielectrophoresis microfluidic chips have been widely used in various biological applications due to their advantages of convenient operation, high throughput, and low cost. However, most of the DEP microfluidic chips are based on 2D planar electrodes which have some limitations, such as electric field attenuation, small effective working regions, and weak DEP forces. In order to overcome the limitations of 2D planar electrodes, two kinds of thick-electrode DEP chips were designed to realize manipulation and multi-parameter measurement of single cells. Based on the multi-electrode structure of thick-electrode DEP, a single-cell 3D electro-rotation chip of "Armillary Sphere" was designed. The chip uses four thick electrodes and a bottom planar electrode to form an electric field chamber, which can control 3D rotation of single cells under different electric signal configurations. Electrical property measurement and 3D image reconstruction of single cells are achieved based on single-cell 3D rotation. This work overcomes the limitations of 2D planar electrodes and effectively solves the problem of unstable spatial position of single-cell samples, and provides a new platform for single-cell analysis. Based on multi-electrode structure of thick-electrode DEP, a microfluidic chip with optoelectronic integration was presented. A dual-fiber optical stretcher embedded in thick electrodes can trap and stretch a single cell while the thick electrodes are used for single-cell rotation. Stretching and rotation manipulation gives the chip the ability to simultaneously measure mechanical and electrical properties of single cells, providing a versatile platform for single-cell analysis, further extending the application of thick-electrode DEP in biological manipulation and analysis.

BioMEMS and Biomedical Nanotechnology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387258434
Total Pages : 554 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis BioMEMS and Biomedical Nanotechnology by : Mihrimah Ozkan

Download or read book BioMEMS and Biomedical Nanotechnology written by Mihrimah Ozkan and published by Springer Science & Business Media. This book was released on 2007-04-03 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributions reporting on fundamental and applied investigations of the material science, biochemistry, and physics of biomedical microdevices with applications to Genomics and Proteomics. Topics include gene expression profiling utilizing microarray technology; imaging and sensing for gene detection and use in DNA analysis; and coverage of advanced microfluidic devices and the Humane Genome Project.

Handbook of Cell Biosensors

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Publisher : Springer
ISBN 13 : 9783030232160
Total Pages : 992 pages
Book Rating : 4.2/5 (321 download)

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Book Synopsis Handbook of Cell Biosensors by : Gérald Thouand

Download or read book Handbook of Cell Biosensors written by Gérald Thouand and published by Springer. This book was released on 2021-10-01 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is an interdisciplinary and comprehensive reference covering all aspects of cell biosensors. It is divided into four main sections which are led and organized by numerous international experts. The scope of coverage includes: Fundamentals and genetics for biosensor applications Transducers, Materials and Systems Markets, innovation and education Application of biosensors in business Biosensor research is an exciting hybrid world where biologists, chemists, physicists, engineers and computer engineers come together. This handbook will serve as an invaluable living resource for all researchers in academia and industry working with cell biosensors.

Dorland's Dictionary of Medical Acronyms and Abbreviations

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323442544
Total Pages : 481 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Dorland's Dictionary of Medical Acronyms and Abbreviations by : Dorland

Download or read book Dorland's Dictionary of Medical Acronyms and Abbreviations written by Dorland and published by Elsevier Health Sciences. This book was released on 2015-07-24 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland's suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. - Symbols section makes it easier to locate unusual or seldom-used symbols. - Convenient alphabetical format allows you to find the entry you need more intuitively. - More than 90,000 entries and definitions. - Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. - New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. - Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).

Label-Free Monitoring of Cells in vitro

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Publisher : Springer Nature
ISBN 13 : 3030324338
Total Pages : 286 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Label-Free Monitoring of Cells in vitro by : Joachim Wegener

Download or read book Label-Free Monitoring of Cells in vitro written by Joachim Wegener and published by Springer Nature. This book was released on 2019-11-18 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is dedicated to label-free, non-invasive monitoring of cell-based assays and it comprises the most widely applied techniques. Each approach is described and critically evaluated by an expert in the field such that researchers get an overview on what is possible and where the limitations are. The book provides the theoretical basis for each technique as well as the most successful and exciting applications. Label-free bioanalytical techniques have been known for a long time as valuable tools to monitor adsorption processes at the solid-liquid interface in general – and biomolecular interaction analysis (BIA) in particular. The underlying concepts have been progressively transferred to the analysis of cell-based assays. The strength of these approaches is implicitly given with the name 'label-free': the readout is independent of any label, reagent or additive that contaminates the system under study and potentially affects its properties. Thus, label-free techniques provide an unbiased analytical perspective in the sense that the sample is not manipulated by additives but pure. They are commonly based on physical principles and read changes in integral physical properties of the sample like refractive index, conductivity, capacitance or elastic modulus to mention just a few. Even though it is not implied in the name, label-free approaches usually monitor the cells under study non-invasively meaning that the amplitude of the signal (e.g. electric field strength, mechanical elongation) that is used for the measurement is too low to interfere or affect. In contrast to label-based analytical techniques that are commonly restricted to a single reading at a predefined time point, label-free approaches allow for a continuous observation so that the dynamics of the biological system or reaction become accessible.

Transport in Biological Media

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Publisher : Newnes
ISBN 13 : 0123978491
Total Pages : 575 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Transport in Biological Media by : Sid M. Becker

Download or read book Transport in Biological Media written by Sid M. Becker and published by Newnes. This book was released on 2013-05-21 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling will find this resource indispensible. - Provides detailed mathematical model development to interpret experiments and provides current modeling practices - Provides a wide range of biological and clinical applications - Includes physiological descriptions of models