Understanding Clinical Research

Download Understanding Clinical Research full books in PDF, epub, and Kindle. Read online Understanding Clinical Research ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Understanding Clinical Research

Author : Renato D. Lopes
Publisher : McGraw Hill Professional
ISBN 13 : 0071792651
Total Pages : 272 pages
Book Rating : 4.0/5 (717 download)

DOWNLOAD NOW!

Book Synopsis Understanding Clinical Research by : Renato D. Lopes

Download or read book Understanding Clinical Research written by Renato D. Lopes and published by McGraw Hill Professional. This book was released on 2013-05-22 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials

The Role of Purchasers and Payers in the Clinical Research Enterprise

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309182905
Total Pages : 120 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis The Role of Purchasers and Payers in the Clinical Research Enterprise by : Institute of Medicine

Download or read book The Role of Purchasers and Payers in the Clinical Research Enterprise written by Institute of Medicine and published by National Academies Press. This book was released on 2002-06-14 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a workshop organized by the Clinical Research roundtable, representatives from purchaser organizations (employers), payer organizations (health plans and insurance companies), and other stakeholder organizations (voluntary health associations, clinical researchers, research organizations, and the technology community) came together to explore: What do purchasers and payers need from the Clinical Research Enterprise? How have current efforts in clinical research met their needs? What are purchasers, payers, and other stakeholders willing to contribute to the enterprise? This book documents these discussions and summarizes what employers and insurers need from and are willing to contribute to clinical research from both a business and a national health care perspective.

An Introduction to Clinical Research

Author : Piers Page
Publisher : OUP Oxford
ISBN 13 : 0191629596
Total Pages : 224 pages
Book Rating : 4.1/5 (916 download)

DOWNLOAD NOW!

Book Synopsis An Introduction to Clinical Research by : Piers Page

Download or read book An Introduction to Clinical Research written by Piers Page and published by OUP Oxford. This book was released on 2011-11-10 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical book is written specifically for junior doctors by a team of highly experienced authors, as an introductory guide to clinical research. It covers all areas that a junior doctor needs to consider, including funding, study design, ethics, data analysis, disseminating findings, and furthering one's research career. It presents a balance view of clinical research and is written by authors actively involved in clinical research both at the 'coal-face' and at a more supervisory level. Research can be a difficult process and it is essential to make sure that the project is set up in the correct way in order to get verifiable results. This easy-to-read guide is available to help junior doctors develop a good study design and present evidence of a sound academic practice, which will make obtaining funding more likely and be time-efficient. Getting started early in research and developing a solid, gradual understanding of clinical research through using this approachable book will be of huge benefit to junior doctors and their discipline.

Understanding Clinical Data Analysis

Author : Ton J. Cleophas
Publisher : Springer
ISBN 13 : 3319395866
Total Pages : 234 pages
Book Rating : 4.3/5 (193 download)

DOWNLOAD NOW!

Book Synopsis Understanding Clinical Data Analysis by : Ton J. Cleophas

Download or read book Understanding Clinical Data Analysis written by Ton J. Cleophas and published by Springer. This book was released on 2016-08-23 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook consists of ten chapters, and is a must-read to all medical and health professionals, who already have basic knowledge of how to analyze their clinical data, but still, wonder, after having done so, why procedures were performed the way they were. The book is also a must-read to those who tend to submerge in the flood of novel statistical methodologies, as communicated in current clinical reports, and scientific meetings. In the past few years, the HOW-SO of current statistical tests has been made much more simple than it was in the past, thanks to the abundance of statistical software programs of an excellent quality. However, the WHY-SO may have been somewhat under-emphasized. For example, why do statistical tests constantly use unfamiliar terms, like probability distributions, hypothesis testing, randomness, normality, scientific rigor, and why are Gaussian curves so hard, and do they make non-mathematicians getting lost all the time? The book will cover the WHY-SOs.

Understanding Clinical Research

Author : Kathryn Biddle
Publisher : Scion Publishing Ltd
ISBN 13 : 1914961315
Total Pages : 202 pages
Book Rating : 4.9/5 (149 download)

DOWNLOAD NOW!

Book Synopsis Understanding Clinical Research by : Kathryn Biddle

Download or read book Understanding Clinical Research written by Kathryn Biddle and published by Scion Publishing Ltd. This book was released on 2023-05-17 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is important for healthcare professionals to understand the basics of clinical research. This book offers a thorough explanation of the principles of clinical research, alongside a wide range of worked examples which show how these principles are applied in practice. Understanding Clinical Research takes readers from how to develop research questions, through the design of research studies, to disseminating research findings. Ethical considerations, research integrity, patient involvement, and study funding are all covered, along with an introduction to the key statistical methods needed for data analysis. Ideal for any healthcare professional: interested in understanding more about the development of evidence-based practice wanting to undertake research but not sure where to start considering or just starting a PhD / MD, or a PGCert in Research Studies

Sharing Clinical Trial Data

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309316324
Total Pages : 304 pages
Book Rating : 4.3/5 (93 download)

DOWNLOAD NOW!

Book Synopsis Sharing Clinical Trial Data by : Institute of Medicine

Download or read book Sharing Clinical Trial Data written by Institute of Medicine and published by National Academies Press. This book was released on 2015-04-20 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research--from funders, to researchers, to journals, to physicians, and ultimately, to patients.

A Practical Guide to Managing Clinical Trials

Author : JoAnn Pfeiffer
Publisher : CRC Press
ISBN 13 : 1315299771
Total Pages : 292 pages
Book Rating : 4.3/5 (152 download)

DOWNLOAD NOW!

Book Synopsis A Practical Guide to Managing Clinical Trials by : JoAnn Pfeiffer

Download or read book A Practical Guide to Managing Clinical Trials written by JoAnn Pfeiffer and published by CRC Press. This book was released on 2017-05-18 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials. Designed for individuals working in research site operations, this user-friendly reference guides the reader through each step of the clinical trial process from site selection, to site set-up, subject recruitment, study visits, and to study close-out. Topics include staff roles/responsibilities/training, budget and contract review and management, subject study visits, data and document management, event reporting, research ethics, audits and inspections, consent processes, IRB, FDA regulations, and good clinical practices. Each chapter concludes with a review of key points and knowledge application. Unique to this book is "A View from India," a chapter-by-chapter comparison of clinical trial practices in India versus the U.S. Throughout the book and in Chapter 10, readers will glimpse some of the challenges and opportunities in the emerging and growing market of Indian clinical trials.

Designing Clinical Research

Author : Stephen B. Hulley
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451165854
Total Pages : 388 pages
Book Rating : 4.4/5 (511 download)

DOWNLOAD NOW!

Book Synopsis Designing Clinical Research by : Stephen B. Hulley

Download or read book Designing Clinical Research written by Stephen B. Hulley and published by Lippincott Williams & Wilkins. This book was released on 2011-11-30 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.

Fast Facts: Medical Statistics

Author : R. Kay
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1912776685
Total Pages : 110 pages
Book Rating : 4.9/5 (127 download)

DOWNLOAD NOW!

Book Synopsis Fast Facts: Medical Statistics by : R. Kay

Download or read book Fast Facts: Medical Statistics written by R. Kay and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-17 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using real examples from oncology trials, but keeping it simple, this concise resource explains the basic principles of medical statistics so that you can better appraise clinical trial results. Key concepts covered in this book include: • hypothesis testing • Kaplan–Meier curves and other graphic representations of data • calculating the power of a study • the stopping rules for efficacy and futility. ' Fast Facts: Medical Statistics' is aimed at all clinicians, clinical scientists, medical writers and regulatory personnel who need a better understanding of the statistical terms and methods used in the planning of studies and the analysis of clinical trial data. If you have ever wanted to know what a type I error is, how an odds ratio is calculated or what a forest plot is really all about, then this is the book for you. Contents: • Statistical inference • Analysis of time-to-event endpoints • Power and sample size • Multiplicity • Interim analysis • Modeling • Graphical methods

Understanding Clinical Papers

Author : David Bowers
Publisher : John Wiley & Sons
ISBN 13 : 1119573165
Total Pages : 304 pages
Book Rating : 4.1/5 (195 download)

DOWNLOAD NOW!

Book Synopsis Understanding Clinical Papers by : David Bowers

Download or read book Understanding Clinical Papers written by David Bowers and published by John Wiley & Sons. This book was released on 2021-03-08 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: For two decades, Understanding Clinical Papers has been helping students and professionals understand the research that supports evidence-based practice. Now in its fourth edition, this popular introductory textbook covers every major aspect of reading and evaluating clinical research literature, from identifying the aims and objectives of a paper to analysing the data with different multivariable methods. Numerous excerpts from actual clinical research papers make learning real and immediate, supported by a unique visual approach that reinforces key points and connects examples with the chapter material. The fourth edition includes extensively revised content throughout, including four brand-new chapters covering qualitative studies, Poisson regression, studies of complex interventions, and research using previously collected data. New and updated material discusses the difference between clinical and statistical significance, the consequences of multiple testing and methods of correction, how topic guides are used to explore and explain participants' experiences, standardised guidelines for writing trials and reviews, and much more. Offering clear explanations of important research-related topics, this reader-friendly resource: Offers a clear, concise, and accessible approach to learning how to read and analyse clinical research literature Features new coverage of qualitative research, including descriptive studies, sampling and populations, and identifying, summarising, and measuring qualitative characteristics Provides new material on missing data, sub-group analysis, feasibility and pilot studies, cluster randomised trials, and adaptive trial designs Includes new tables, abstracts, and excerpts from recent clinical research literature Understanding Clinical Papers is essential reading for all healthcare professionals and students, particularly those involved in clinical work and medical research, as well as general readers wanting to improve their understanding of research literature.

Strategy and Statistics in Clinical Trials

Author : Joseph Tal
Publisher : Academic Press
ISBN 13 : 0123869927
Total Pages : 278 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!

Book Synopsis Strategy and Statistics in Clinical Trials by : Joseph Tal

Download or read book Strategy and Statistics in Clinical Trials written by Joseph Tal and published by Academic Press. This book was released on 2011-06-26 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategy and Statistics in Clinical Trials deals with the research processes and the role of statistics in these processes. The book offers real-life case studies and provides a practical, how to guide to biomedical R&D. It describes the statistical building blocks and concepts of clinical trials and promotes effective cooperation between statisticians and important other parties. The discussion is organized around 15 chapters. After providing an overview of clinical development and statistics, the book explores questions when planning clinical trials, along with the attributes of medical products. It then explains how to set research objectives and goes on to consider statistical thinking, estimation, testing procedures, and statistical significance, explanation and prediction. The rest of the book focuses on exploratory and confirmatory clinical trials; hypothesis testing and multiplicity; elements of clinical trial design; choosing trial endpoints; and determination of sample size. This book is for all individuals engaged in clinical research who are interested in a better understanding of statistics, including professional clinical researchers, professors, physicians, and researchers in laboratory. It will also be of interest to corporate and government laboratories, clinical research nurses, members of the allied health professions, and post-doctoral and graduate students. Enables non-statisticians to better understand research processes and statistics' role in these processes Offers real-life case studies and provides a practical, "how to" guide to biomedical R&D Delineates the statistical building blocks and concepts of clinical trials Promotes effective cooperation between statisticians and important other parties

Understanding Clinical Trials and Research

Author : Ruth Sheard
Publisher :
ISBN 13 : 9781925651287
Total Pages : 64 pages
Book Rating : 4.6/5 (512 download)

DOWNLOAD NOW!

Book Synopsis Understanding Clinical Trials and Research by : Ruth Sheard

Download or read book Understanding Clinical Trials and Research written by Ruth Sheard and published by . This book was released on 2018-07 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: This booklet contains information about clinical research with a focus on clinical trials. It includes information about how to get involved in a clinical trial and practical issues to consider when deciding whether to take part. It was developed with help from a range of health professionals and people who have taken part in clinical trials.

The Practical Guide to Clinical Research and Publication

Author : Uzung Yoon
Publisher : Academic Press
ISBN 13 : 0128245182
Total Pages : 224 pages
Book Rating : 4.1/5 (282 download)

DOWNLOAD NOW!

Book Synopsis The Practical Guide to Clinical Research and Publication by : Uzung Yoon

Download or read book The Practical Guide to Clinical Research and Publication written by Uzung Yoon and published by Academic Press. This book was released on 2021-08-03 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Practical Guide to Clinical Research and Publication provides a comprehensive overview of the key foundations of epidemiology, statistics and epidemiological studies. This book presents the most important terms and knowledge in the field from a medical point-of-view. Sections contain numerous, clinically-oriented examples and drawings to facilitate understanding and clarify the relation to clinic and practice. The book contains many graphics and key points for easier understanding and is written using bullet points for ease of use and comprehension. It is ideal for physicians and clinical researchers who want to use it as guidance for clinical research or teaching. Contains numerous, clinically-oriented examples and drawings Provides an explanation of epidemiology and statistics to aid understanding of clinical research Written by a physician with extensive knowledge in research

Quick Guide to Good Clinical Practice

Author : Cemal Cingi
Publisher : Springer
ISBN 13 : 3319443445
Total Pages : 237 pages
Book Rating : 4.3/5 (194 download)

DOWNLOAD NOW!

Book Synopsis Quick Guide to Good Clinical Practice by : Cemal Cingi

Download or read book Quick Guide to Good Clinical Practice written by Cemal Cingi and published by Springer. This book was released on 2016-11-15 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brand-new book offers a reference guide to understanding and applying the rules for properly conducting clinical trials to meet the international quality standard – Good Clinical Practice – provided by the International Conference on Harmonization (ICH). The work offers an updated perspective on the clinical research landscape within the context of the clinical trial regulatory frameworks in Europe and the USA. In addition to providing a historical review and a detailed definition of GPC regulations, it includes step-by-step explanations of all the requirements that researchers should bear in mind when designing and performing new trials. Further topics covered include: ethics of clinical research; the drug development process and evolution of regulations; investigator and sponsor responsibilities; and clinical trial protocols. Written by clinicians for clinicians, the book represents a valuable read also for researchers, pharmacists and all professionals involved in applications to the ethic committees, whose approval is required for new clinical studies.

Understanding Clinical Investigations

Author : Susan Skinner
Publisher : Elsevier Health Sciences
ISBN 13 : 0702026832
Total Pages : 344 pages
Book Rating : 4.7/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Understanding Clinical Investigations by : Susan Skinner

Download or read book Understanding Clinical Investigations written by Susan Skinner and published by Elsevier Health Sciences. This book was released on 2005-06-02 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This indispensable handbook provides easily accessible explanations of the common investigations carried out on all body systems. It addresses the relationship between normal physiology and disease processes and the place of clinical investigation within these events. The rationale for investigation is made clear and some guidance for further care is offered. In this new edition each investigation has been updated in line in the light of recent guidelines and practice. New material has been added including chromosome studies and blood cholesterol values. Designed to give quickly referenced guidance on a broad spectrum of clinical investigation and monitoring, it will be helpful to all nursing staff and will assist in giving explaining tests to patients. Comprehensive range of common clinical investigations Combines normal physiology and clinical investigations and pathophysiology Appendix of normal values New design and format Each investigation has been updated in line in the light of recent guidelines and practice. New material has been added including chromosome studies and blood cholesterol values

Ethical Considerations When Preparing a Clinical Research Protocol

Author : Evan DeRenzo
Publisher : Academic Press
ISBN 13 : 0123869358
Total Pages : 368 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!

Book Synopsis Ethical Considerations When Preparing a Clinical Research Protocol by : Evan DeRenzo

Download or read book Ethical Considerations When Preparing a Clinical Research Protocol written by Evan DeRenzo and published by Academic Press. This book was released on 2020-06-25 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ethical Considerations When Preparing a Clinical Research Protocol, Second Edition, provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. It includes practical information on ethical principles in clinical research, how to design appropriate research studies, how to consent and assent documents, how to get protocols approved, special populations, confidentiality issues, and the reporting of adverse events. The book's valuable appendix includes a listing of web resources about research ethics, along with a glossary, making it an invaluable resource for scientists collaborating in clinical trials, physician investigators, clinical research fellows, and more. Walks investigators and trainees through the identification of the ethical aspects of each section of a clinical research protocol Includes case histories that illustrate key points Contains information on conducting clinical research within the pharmaceutical industry Includes internet resources and worldwide web addresses for important research ethics documents and regulations Contains a chapter on Study Design and Methodology that is purposely expanded to explicitly address biostatistical considerations

Developing a Successful Clinical Research Program

Author : Cara East
Publisher : Springer
ISBN 13 : 3319546937
Total Pages : 270 pages
Book Rating : 4.3/5 (195 download)

DOWNLOAD NOW!

Book Synopsis Developing a Successful Clinical Research Program by : Cara East

Download or read book Developing a Successful Clinical Research Program written by Cara East and published by Springer. This book was released on 2018-08-08 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book is designed to help a medical team become a clinical research team. It includes practical information and tips for the initial stages of clinical research: building a team, negotiating a contract, developing a budget, and writing and improving a patient consent. Chapters describing the nuts and bolts of how to actually perform the study follow, including patient recruiting and retention, screening, follow-ups and handling monitor visits. Finally, there is discussion of the yearly reviews and disclosures and not just surviving, but acing, the all-important Food and Drug Administration audit. Clinical research moves medicine forward and is a necessary part of bringing any new therapy, device, or procedure into routine medical care. However, it can be costly and convoluted, and the methodologies of clinical research are not widely standardized. Decreasing some of the chaos present in American clinical research is the primary goal of this book. The second goal is to improve the understanding and education of those who enter clinical research, whether in the frontline work of the clinical research site, in the middleman companies who have a high turnover rate, at a research hospital or institution, or at medical corporations that depend on good clinical research to bring their products to market. The third reason is to standardize American clinical research and to remove some of the vagaries and inconsistencies in the field. Practical and user-friendly, Developing a Successful Clinical Research Program fills a need for a clear guide to developing and improving a first-class research program in any clinical setting.