Treatment Planning of High Dose-Rate Brachytherapy - Mathematical Modelling and Optimization

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Publisher : Linköping University Electronic Press
ISBN 13 : 9179297382
Total Pages : 53 pages
Book Rating : 4.1/5 (792 download)

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Book Synopsis Treatment Planning of High Dose-Rate Brachytherapy - Mathematical Modelling and Optimization by : Björn Morén

Download or read book Treatment Planning of High Dose-Rate Brachytherapy - Mathematical Modelling and Optimization written by Björn Morén and published by Linköping University Electronic Press. This book was released on 2021-01-12 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a widespread class of diseases that each year affects millions of people. It is mostly treated with chemotherapy, surgery, radiation therapy, or combinations thereof. High doserate (HDR) brachytherapy (BT) is one modality of radiation therapy, which is used to treat for example prostate cancer and gynecologic cancer. In BT, catheters (i.e., hollow needles) or applicators are used to place a single, small, but highly radioactive source of ionizing radiation close to or within a tumour, at dwell positions. An emerging technique for HDR BT treatment is intensity modulated brachytherapy (IMBT), in which static or dynamic shields are used to further shape the dose distribution, by hindering the radiation in certain directions. The topic of this thesis is the application of mathematical optimization to model and solve the treatment planning problem. The treatment planning includes decisions on catheter placement, that is, how many catheters to use and where to place them, as well as decisions for dwell times. Our focus is on the latter decisions. The primary treatment goals are to give the tumour a sufficiently high radiation dose while limiting the dose to the surrounding healthy organs, to avoid severe side effects. Because these aims are typically in conflict, optimization models of the treatment planning problem are inherently multiobjective. Compared to manual treatment planning, there are several advantages of using mathematical optimization for treatment planning. First, the optimization of treatment plans requires less time, compared to the time-consuming manual planning. Secondly, treatment plan quality can be improved by using optimization models and algorithms. Finally, with the use of sophisticated optimization models and algorithms the requirements of experience and skill level for the planners are lower. The use of optimization for treatment planning of IMBT is especially important because the degrees of freedom are too many for manual planning. The contributions of this thesis include the study of properties of treatment planning models, suggestions for extensions and improvements of proposed models, and the development of new optimization models that take clinically relevant, but uncustomary aspects, into account in the treatment planning. A common theme is the modelling of constraints on dosimetric indices, each of which is a restriction on the portion of a volume that receives at least a specified dose, or on the lowest dose that is received by a portion of a volume. Modelling dosimetric indices explicitly yields mixed-integer programs which are computationally demanding to solve. We have therefore investigated approximations of dosimetric indices, for example using smooth non-linear functions or convex functions. Contributions of this thesis are also a literature review of proposed treatment planning models for HDR BT, including mathematical analyses and comparisons of models, and a study of treatment planning for IMBT, which shows how robust optimization can be used to mitigate the risks from rotational errors in the shield placement. Cancer är en grupp av sjukdomar som varje år drabbar miljontals människor. De vanligaste behandlingsformerna är cellgifter, kirurgi, strålbehandling eller en kombination av dessa. I denna avhandling studeras högdosrat brachyterapi (HDR BT), vilket är en form av strålbehandling som till exempel används vid behandling av prostatacancer och gynekologisk cancer. Vid brachyterapibehandling används ihåliga nålar eller applikatorer för att placera en millimeterstor strålkälla antingen inuti eller intill en tumör. I varje nål finns det ett antal så kallade dröjpositioner där strålkällan kan stanna en viss tid för att bestråla den omkringliggande vävnaden, i alla riktningar. Genom att välja lämpliga tider för dröjpositionerna kan dosfördelningen formas efter patientens anatomi. Utöver HDR BT studeras också den nya tekniken intensitetsmodulerad brachyterapi (IMBT) vilket är en variation på HDR BT där skärmning används för att minska strålningen i vissa riktningar vilket gör det möjligt att forma dosfördelningen bättre. Planeringen av en behandling med HDR BT omfattar hur många nålar som ska användas, var de ska placeras samt hur länge strålkällan ska stanna i de olika dröjpositionerna. För HDR BT kan dessa vara flera hundra stycken medan det för IMBT snarare handlar om tusentals möjliga kombinationer av dröjpositioner och inställningar av skärmarna. Planeringen resulterar i en dosplan som beskriver hur hög stråldos som tumören och intilliggande frisk vävnad och riskorgan utsätts för. Dosplaneringen kan formuleras som ett matematiskt optimeringsproblem vilket är ämnet för avhandlingen. De övergripande målsättningarna för behandlingen är att ge en tillräckligt hög stråldos till tumören, för att döda alla cancerceller, samt att undvika att bestråla riskorgan eftersom det kan ge allvarliga biverkningar. Då alla målsättningarna inte samtidigt kan uppnås fullt ut så fås optimeringsproblem där flera målsättningar behöver prioriteras mot varandra. Utöver att dosplanen uppfyller kliniska behandlingsriktlinjer så är också tidsaspekten av planeringen viktig eftersom det är vanligt att den görs medan patienten är bedövad eller sövd. Vid utvärdering av en dosplan används dos-volymmått. För en tumör anger ett dosvolymmått hur stor andel av tumören som får en stråldos som är högre än en specificerad nivå. Dos-volymmått utgör en viktig del av målen för dosplaner som tas upp i kliniska behandlingsriktlinjer och ett exempel på ett sådant mål vid behandling av prostatacancer är att 95% av prostatans volym ska få en stråldos som är minst den föreskrivna dosen. Dos-volymmått utläses ur de kliniskt betydelsefulla dos-volym histogrammen som för varje stråldosnivå anger motsvarande volym som erhåller den dosen. En fördel med att använda matematisk optimering för dosplanering är att det kan spara tid jämfört med manuell planering. Med väl utvecklade modeller så finns det också möjlighet att skapa bättre dosplaner, till exempel genom att riskorganen nås av en lägre dos men med bibehållen dos till tumören. Vidare så finns det även fördelar med en process som inte är lika personberoende och som inte kräver erfarenhet i lika stor utsträckning som manuell dosplanering i dagsläget gör. Vid IMBT är det dessutom så många frihetsgrader att manuell planering i stort sett blir omöjligt. I avhandlingen ligger fokus på hur dos-volymmått kan användas och modelleras explicit i optimeringsmodeller, så kallade dos-volymmodeller. Detta omfattar såväl analys av egenskaper hos befintliga modeller, utvidgningar av tidigare använda modeller samt utveckling av nya optimeringsmodeller. Eftersom dos-volymmodeller modelleras som heltalsproblem, vilka är beräkningskrävande att lösa, så är det också viktigt att utveckla algoritmer som kan lösa dem tillräckligt snabbt för klinisk användning. Ett annat mål för modellutvecklingen är att kunna ta hänsyn till fler kriterier som är kliniskt relevanta men som inte ingår i dos-volymmodeller. En sådan kategori av mått är hur dosen är fördelad rumsligt, exempelvis att volymen av sammanhängande områden som får en alldeles för hög dos ska vara liten. Sådana områden går dock inte att undvika helt eftersom det är typiskt för dosplaner för brachyterapi att stråldosen fördelar sig ojämnt, med väldigt höga doser till små volymer precis intill strålkällorna. Vidare studeras hur små fel i inställningarna av skärmningen i IMBT påverkar dosplanens kvalitet och de olika utvärderingsmått som används kliniskt. Robust optimering har använts för att säkerställa att en dosplan tas fram som är robust sett till dessa möjliga fel i hur skärmningen är placerad. Slutligen ges en omfattande översikt över optimeringsmodeller för dosplanering av HDR BT och speciellt hur optimeringsmodellerna hanterar de motstridiga målsättningarna.

Mathematical Modelling of Dose Planning in High Dose-Rate Brachytherapy

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Publisher : Linköping University Electronic Press
ISBN 13 : 9176851311
Total Pages : 63 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Mathematical Modelling of Dose Planning in High Dose-Rate Brachytherapy by : Björn Morén

Download or read book Mathematical Modelling of Dose Planning in High Dose-Rate Brachytherapy written by Björn Morén and published by Linköping University Electronic Press. This book was released on 2019-04-24 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a widespread type of diseases that each year affects millions of people. It is mainly treated by chemotherapy, surgery or radiation therapy, or a combination of them. One modality of radiation therapy is high dose-rate brachytherapy, used in treatment of for example prostate cancer and gynecologic cancer. Brachytherapy is an invasive treatment in which catheters (hollow needles) or applicators are used to place the highly active radiation source close to or within a tumour. The treatment planning problem, which can be modelled as a mathematical optimization problem, is the topic of this thesis. The treatment planning includes decisions on how many catheters to use and where to place them as well as the dwell times for the radiation source. There are multiple aims with the treatment and these are primarily to give the tumour a radiation dose that is sufficiently high and to give the surrounding healthy tissue and organs (organs at risk) a dose that is sufficiently low. Because these aims are in conflict, modelling the treatment planning gives optimization problems which essentially are multiobjective. To evaluate treatment plans, a concept called dosimetric indices is commonly used and they constitute an essential part of the clinical treatment guidelines. For the tumour, the portion of the volume that receives at least a specified dose is of interest while for an organ at risk it is rather the portion of the volume that receives at most a specified dose. The dosimetric indices are derived from the dose-volume histogram, which for each dose level shows the corresponding dosimetric index. Dose-volume histograms are commonly used to visualise the three-dimensional dose distribution. The research focus of this thesis is mathematical modelling of the treatment planning and properties of optimization models explicitly including dosimetric indices, which the clinical treatment guidelines are based on. Modelling dosimetric indices explicitly yields mixedinteger programs which are computationally demanding to solve. The computing time of the treatment planning is of clinical relevance as the planning is typically conducted while the patient is under anaesthesia. Research topics in this thesis include both studying properties of models, extending and improving models, and developing new optimization models to be able to take more aspects into account in the treatment planning. There are several advantages of using mathematical optimization for treatment planning in comparison to manual planning. First, the treatment planning phase can be shortened compared to the time consuming manual planning. Secondly, also the quality of treatment plans can be improved by using optimization models and algorithms, for example by considering more of the clinically relevant aspects. Finally, with the use of optimization algorithms the requirements of experience and skill level for the planners are lower. This thesis summary contains a literature review over optimization models for treatment planning, including the catheter placement problem. How optimization models consider the multiobjective nature of the treatment planning problem is also discussed.

Emerging Technologies in Brachytherapy

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Publisher : CRC Press
ISBN 13 : 1498736548
Total Pages : 416 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Emerging Technologies in Brachytherapy by : William Y. Song

Download or read book Emerging Technologies in Brachytherapy written by William Y. Song and published by CRC Press. This book was released on 2017-05-19 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brachytherapy is continuously advancing. Years of accumulated experience have led to clinical evidence of its benefit in numerous clinical sites such as gynecological, prostate, breast, rectum, ocular, and many other cancers. Brachytherapy continues to expand in its scope of practice and complexity, driven by strong academic and commercial research, by advances in competing modalities, and due to the diversity in the political and economic landscape. It is a true challenge for practicing professionals and students to readily grasp the overarching trends of the field, especially of those technologies and innovative practices that are not yet established but are certainly on the rise. Addressing this challenge, Emerging Technologies in Brachytherapy presents a comprehensive collection of chapters on the latest trending/emerging technologies and expert opinions. It is divided into five broad sections: Section I: Physics of Brachytherapy Section II: Imaging for Brachytherapy Guidance Section III: Brachytherapy Suites Section IV: Is Brachytherapy a Competitive Modality? Section V: Vision 20/20: Industry Perspective Each section has a carefully selected collection of chapters, which covers the spectrum of topics in comprehensive detail. By drawing on recognized experts and key opinion leaders from academia and commercial sectors worldwide (100+ contributors), Emerging Technologies in Brachytherapy provides readers with a wealth of relevant information needed to comprehend the rapidly advancing technologies and trends of today and the prospects for the future.

Optimization of Human Cancer Radiotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642464416
Total Pages : 293 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Optimization of Human Cancer Radiotherapy by : G.W. Swan

Download or read book Optimization of Human Cancer Radiotherapy written by G.W. Swan and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mathematical models in this book are concerned with a variety of approaches to the manner in which the clinical radiologic treatment of human neoplasms can be improved. These improvements comprise ways of delivering radiation to the malignan cies so as to create considerable damage to tumor cells while sparing neighboring normal tissues. There is no unique way of dealing with these improvements. Accord ingly, in this book a number of different presentations are given. Each presentation has as its goal some aspect of the improvement, or optimization, of radiotherapy. This book is a collection of current ideas concerned with the optimization of human cancer radiotherapy. It is hoped that readers will build on this collection and develop superior approaches for the understanding of the ways to improve therapy. The author owes a special debt of thanks to Kathy Prindle who breezed through the typing of this book with considerable dexterity. TABLE OF CONTENTS Chapter GENERAL INTRODUCTION 1. 1 Introduction 1 1. 2 History of Cancer and its Treatment by Radiotherapy 8 1. 3 Some Mathematical Models of Tumor Growth 12 1. 4 Spatial Distribution of the Radiation Dose 20 Chapter 2 SURVIVAL CURVES FROM STATISTICAL MODELS 24 2. 1 Introduction 24 2. 2 The Target Model 26 2. 3 Single-hit-to-kill Model 27 2. 4 Multitarget, Single-hit Survival 29 2. 5 Multitarget, Multihit Survival 31 2. 6 Single-target, Multihit Survival 31 2.

Decision Analytics and Optimization in Disease Prevention and Treatment

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Publisher : John Wiley & Sons
ISBN 13 : 1118960122
Total Pages : 406 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Decision Analytics and Optimization in Disease Prevention and Treatment by : Nan Kong

Download or read book Decision Analytics and Optimization in Disease Prevention and Treatment written by Nan Kong and published by John Wiley & Sons. This book was released on 2018-03-13 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: A systematic review of the most current decision models and techniques for disease prevention and treatment Decision Analytics and Optimization in Disease Prevention and Treatment offers a comprehensive resource of the most current decision models and techniques for disease prevention and treatment. With contributions from leading experts in the field, this important resource presents information on the optimization of chronic disease prevention, infectious disease control and prevention, and disease treatment and treatment technology. Designed to be accessible, in each chapter the text presents one decision problem with the related methodology to showcase the vast applicability of operations research tools and techniques in advancing medical decision making. This vital resource features the most recent and effective approaches to the quickly growing field of healthcare decision analytics, which involves cost-effectiveness analysis, stochastic modeling, and computer simulation. Throughout the book, the contributors discuss clinical applications of modeling and optimization techniques to assist medical decision making within complex environments. Accessible and authoritative, Decision Analytics and Optimization in Disease Prevention and Treatment: Presents summaries of the state-of-the-art research that has successfully utilized both decision analytics and optimization tools within healthcare operations research Highlights the optimization of chronic disease prevention, infectious disease control and prevention, and disease treatment and treatment technology Includes contributions by well-known experts from operations researchers to clinical researchers, and from data scientists to public health administrators Offers clarification on common misunderstandings and misnomers while shedding light on new approaches in this growing area Designed for use by academics, practitioners, and researchers, Decision Analytics and Optimization in Disease Prevention and Treatment offers a comprehensive resource for accessing the power of decision analytics and optimization tools within healthcare operations research.

Radiation Therapy Physics

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Publisher : Springer Science & Business Media
ISBN 13 : 3662031078
Total Pages : 468 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Radiation Therapy Physics by : Alfred R. Smith

Download or read book Radiation Therapy Physics written by Alfred R. Smith and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide a uniquely comprehensive source of information on the entire field of radiation therapy physics. The very significant advances in imaging, computational, and accelerator technologies receive full consideration, as do such topics as the dosimetry of radiolabeled antibodies and dose calculation models. The scope of the book and the expertise of the authors make it essential reading for interested physicians and physicists and for radiation dosimetrists.

Operations Research Proceedings 2017

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Publisher : Springer
ISBN 13 : 3319899201
Total Pages : 758 pages
Book Rating : 4.3/5 (198 download)

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Book Synopsis Operations Research Proceedings 2017 by : Natalia Kliewer

Download or read book Operations Research Proceedings 2017 written by Natalia Kliewer and published by Springer. This book was released on 2018-05-25 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers a selection of peer-reviewed papers presented at the International Conference on Operations Research (OR 2017), which was held at Freie Universität Berlin, Germany on September 6-8, 2017. More than 800 scientists, practitioners and students from mathematics, computer science, business/economics and related fields attended the conference and presented more than 500 papers in parallel topic streams, as well as special award sessions. The main theme of the conference and its proceedings was "Decision Analytics for the Digital Economy."

Personalization in Modern Radiation Oncology: Methods, Results and Pitfalls

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Publisher : Frontiers Media SA
ISBN 13 : 2889766373
Total Pages : 257 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Personalization in Modern Radiation Oncology: Methods, Results and Pitfalls by : Francesco Cellini

Download or read book Personalization in Modern Radiation Oncology: Methods, Results and Pitfalls written by Francesco Cellini and published by Frontiers Media SA. This book was released on 2022-07-28 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiobjective Optimization in Imrt Treatment Planning

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Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783838372631
Total Pages : 196 pages
Book Rating : 4.3/5 (726 download)

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Book Synopsis Multiobjective Optimization in Imrt Treatment Planning by : Lizhen Shao

Download or read book Multiobjective Optimization in Imrt Treatment Planning written by Lizhen Shao and published by LAP Lambert Academic Publishing. This book was released on 2010-07 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of intensity modulated radiation therapy (IMRT) is to kill tumor cells while at the same time protecting the surrounding tissue and organs from the damaging effect of radiation. Given the number of beams and beam directions, beam intensity optimization needs to determine beam intensity profiles that yield the best dose distribution under consideration of clinical and physical constraints. In this book, we first review existing mathematical models and computation methods for the beam intensity optimization problem. Then we formulate the beam intensity optimization problem as a multiobjective linear programme (MOLP) with three objectives. The rest of the book is dedicated to developing methods to solve this large MOLP efficiently and to the application in the beam intensity optimization problem. The book provides the necessary mathmatical foundation of multiobjective optimization to solve multiobjective linear programming problems. It is well suitable to be used as a reference book on multiobjective optimization. Moreover it should also be useful to professionals who may be considering using multiobjective optimization.

Technical Basis of Radiation Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642115713
Total Pages : 1145 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Technical Basis of Radiation Therapy by : Seymour H. Levitt

Download or read book Technical Basis of Radiation Therapy written by Seymour H. Levitt and published by Springer Science & Business Media. This book was released on 2012-01-25 with total page 1145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a detailed examination of the technological basis of radiation therapy. It is jointly written by North American and European authors, which broadens the contents and increases the book’s applicability in daily practice throughout the world.

Applications of Multi-objective Evolutionary Algorithms

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Publisher : World Scientific
ISBN 13 : 9812561064
Total Pages : 792 pages
Book Rating : 4.8/5 (125 download)

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Book Synopsis Applications of Multi-objective Evolutionary Algorithms by : Carlos A. Coello Coello

Download or read book Applications of Multi-objective Evolutionary Algorithms written by Carlos A. Coello Coello and published by World Scientific. This book was released on 2004 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Detailed MOEA applications discussed by international experts - State-of-the-art practical insights in tackling statistical optimization with MOEAs - A unique monograph covering a wide spectrum of real-world applications - Step-by-step discussion of MOEA applications in a variety of domains

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1840 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 2520 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

World Congress on Medical Physics and Biomedical Engineering September 7 - 12, 2009 Munich, Germany

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Publisher : Springer Science & Business Media
ISBN 13 : 3642034748
Total Pages : 1112 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis World Congress on Medical Physics and Biomedical Engineering September 7 - 12, 2009 Munich, Germany by : Olaf Dössel

Download or read book World Congress on Medical Physics and Biomedical Engineering September 7 - 12, 2009 Munich, Germany written by Olaf Dössel and published by Springer Science & Business Media. This book was released on 2010-01-01 with total page 1112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Present Your Research to the World! The World Congress 2009 on Medical Physics and Biomedical Engineering – the triennial scientific meeting of the IUPESM - is the world’s leading forum for presenting the results of current scientific work in health-related physics and technologies to an international audience. With more than 2,800 presentations it will be the biggest conference in the fields of Medical Physics and Biomedical Engineering in 2009! Medical physics, biomedical engineering and bioengineering have been driving forces of innovation and progress in medicine and healthcare over the past two decades. As new key technologies arise with significant potential to open new options in diagnostics and therapeutics, it is a multidisciplinary task to evaluate their benefit for medicine and healthcare with respect to the quality of performance and therapeutic output. Covering key aspects such as information and communication technologies, micro- and nanosystems, optics and biotechnology, the congress will serve as an inter- and multidisciplinary platform that brings together people from basic research, R&D, industry and medical application to discuss these issues. As a major event for science, medicine and technology the congress provides a comprehensive overview and in–depth, first-hand information on new developments, advanced technologies and current and future applications. With this Final Program we would like to give you an overview of the dimension of the congress and invite you to join us in Munich! Olaf Dössel Congress President Wolfgang C.

Advances and Trends in Optimization with Engineering Applications

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Publisher : SIAM
ISBN 13 : 1611974674
Total Pages : 730 pages
Book Rating : 4.6/5 (119 download)

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Book Synopsis Advances and Trends in Optimization with Engineering Applications by : Tamas Terlaky

Download or read book Advances and Trends in Optimization with Engineering Applications written by Tamas Terlaky and published by SIAM. This book was released on 2017-04-26 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optimization is of critical importance in engineering. Engineers constantly strive for the best possible solutions, the most economical use of limited resources, and the greatest efficiency. As system complexity increases, these goals mandate the use of state-of-the-art optimization techniques. In recent years, the theory and methodology of optimization have seen revolutionary improvements. Moreover, the exponential growth in computational power, along with the availability of multicore computing with virtually unlimited memory and storage capacity, has fundamentally changed what engineers can do to optimize their designs. This is a two-way process: engineers benefit from developments in optimization methodology, and challenging new classes of optimization problems arise from novel engineering applications. Advances and Trends in Optimization with Engineering Applications reviews 10 major areas of optimization and related engineering applications, providing a broad summary of state-of-the-art optimization techniques most important to engineering practice. Each part provides a clear overview of a specific area and discusses a range of real-world problems. The book provides a solid foundation for engineers and mathematical optimizers alike who want to understand the importance of optimization methods to engineering and the capabilities of these methods.

Abeloff's Clinical Oncology E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 1455728810
Total Pages : 2712 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Abeloff's Clinical Oncology E-Book by : John E. Niederhuber

Download or read book Abeloff's Clinical Oncology E-Book written by John E. Niederhuber and published by Elsevier Health Sciences. This book was released on 2013-09-12 with total page 2712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.

Practical Radiation Oncology Physics E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323263755
Total Pages : 400 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Practical Radiation Oncology Physics E-Book by : Sonja Dieterich

Download or read book Practical Radiation Oncology Physics E-Book written by Sonja Dieterich and published by Elsevier Health Sciences. This book was released on 2015-06-24 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perfect for radiation oncologists, medical physicists, and residents in both fields, Practical Radiation Oncology Physics provides a concise and practical summary of the current practice standards in therapeutic medical physics. A companion to the fourth edition of Clinical Radiation Oncology, by Drs. Leonard Gunderson and Joel Tepper, this indispensable guide helps you ensure a current, state-of-the art clinical practice. Covers key topics such as relative and in-vivo dosimetry, imaging and clinical imaging, stereotactic body radiation therapy, and brachytherapy. Describes technical aspects and patient-related aspects of current clinical practice. Offers key practice guideline recommendations from professional societies throughout — including AAPM, ASTRO, ABS, ACR, IAEA, and others. Includes therapeutic applications of x-rays, gamma rays, electron and charged particle beams, neutrons, and radiation from sealed radionuclide sources, plus the equipment associated with their production, use, measurement, and evaluation. Features a "For the Physician" box in each chapter, which summarizes the key points with the most impact on the quality and safety of patient care. Provides a user-friendly appendix with annotated compilations of all relevant recommendation documents. Medicine eBook is accessible on a variety of devices.