Treatment Of Cystic Fibrosis And Other Rare Lung Diseases

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Treatment of Cystic Fibrosis and Other Rare Lung Diseases

Author : Arata Azuma
Publisher : Springer
ISBN 13 : 3034809778
Total Pages : 266 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Treatment of Cystic Fibrosis and Other Rare Lung Diseases by : Arata Azuma

Download or read book Treatment of Cystic Fibrosis and Other Rare Lung Diseases written by Arata Azuma and published by Springer. This book was released on 2017-01-28 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the pathogenesis and pathophysiology of several pulmonary diseases as well as their treatment. It also discusses the underlying genetic and molecular biological basis, which opens the way for new treatments for these conditions. It focuses on the treatment of cystic fibrosis including CFTR (cystic fibrosis transmembrane-conductance regulator) modulator therapies, drug therapies that augment airway surface liquid as well as anti-inflammatory and anti-infective therapies. Further topics include long-term, low-dose macrolide therapy for diffuse panbronchiolitis; novel agents for previously untreatable idiopathic pulmonary fibrosis; possible new treatments for pulmonary alveolar proteinosis (PAP); and multiple novel therapeutic targets for treating lymphangiomyomatosis. Research into these conditions has led to major advances in our understanding of the underlying genetic and molecular basis of this disease, and to dramatic improvements in survival and quality of life for affected individuals.

Orphan Lung Diseases

Author : Vincent Cottin
Publisher : Springer
ISBN 13 : 1447124014
Total Pages : 623 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Orphan Lung Diseases by : Vincent Cottin

Download or read book Orphan Lung Diseases written by Vincent Cottin and published by Springer. This book was released on 2015-01-10 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Orphan Lung Diseases: A Clinical Guide to Rare Lung Disease provides a comprehensive, clinically focused textbook on rare and so-called ‘orphan’ pulmonary diseases. The book is oriented towards the diagnostic approach, including manifestations suggesting the disease, diagnostic criteria, methods of diagnostic confirmation, and differential diagnosis, with an overview of management.

Molecular Basis of Pulmonary Disease

Author : Francis X. McCormack
Publisher : Springer Science & Business Media
ISBN 13 : 1597453846
Total Pages : 443 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Molecular Basis of Pulmonary Disease by : Francis X. McCormack

Download or read book Molecular Basis of Pulmonary Disease written by Francis X. McCormack and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Lung Disease: Insights from Rare Disorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy to read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture’s syndromes to Sarcoidosis and alpha one titrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis of Lung Disease: Insights from Rare Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.

Stem Cell-Based Therapy for Lung Disease

Author : Janette K. Burgess
Publisher : Springer Nature
ISBN 13 : 303029403X
Total Pages : 260 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Stem Cell-Based Therapy for Lung Disease by : Janette K. Burgess

Download or read book Stem Cell-Based Therapy for Lung Disease written by Janette K. Burgess and published by Springer Nature. This book was released on 2019-11-23 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.

Rare Lung Diseases

Author : Sujith V. Cherian
Publisher : CRC Press
ISBN 13 : 1000804887
Total Pages : 671 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Rare Lung Diseases by : Sujith V. Cherian

Download or read book Rare Lung Diseases written by Sujith V. Cherian and published by CRC Press. This book was released on 2023-03-13 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to be a complete guide to diagnose, manage, and treat rare lung diseases encountered by practicing pulmonologists and trainees. It extensively covers the "more common" of the rare lung diseases, categorizing them based on developmental lung anomalies in adults, airway disorders, diffuse parenchymal lung diseases, neoplasms, rare vascular disorders, and other miscellaneous conditions. This comprehensive review facilitates the study and understanding of this complex and diverse set of disorders, focusing on differential diagnosis, evidence-based discussions of management algorithms, and thoughtful analysis of treatment options. Key Features * Reviews multiple rare lung diseases, including ones acquired congenitally to be expressed in old age * Enriched with case studies and illustrations to guide respiratory physicians and trainees to devise an effective treatment plan *Focuses on concerned investigations, with a section on the role of new procedures in management

Diffuse Cystic Lung Diseases

Author : Nishant Gupta
Publisher : Springer Nature
ISBN 13 : 3030633659
Total Pages : 384 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Diffuse Cystic Lung Diseases by : Nishant Gupta

Download or read book Diffuse Cystic Lung Diseases written by Nishant Gupta and published by Springer Nature. This book was released on 2021-01-28 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive reference on diffuse cystic lung diseases (DCLDs). DCLDs are a group of pathophysiologically heterogenous processes that are characterized by the presence of multiple spherical or irregularly shaped, thin-walled, air-filled spaces within the pulmonary parenchyma. In recent years, tremendous advancements have been made in these diseases leading to improved understanding of the underlying pathophysiology, and improved outcomes with targeted therapies. The authors, who are leading experts in the field, delineate DCLDs as a separate category distinct from other interstitial lung diseases, and have created this textbook specifically dedicated to this disease group. This book begins with a chapter introducing the definition and classification of DCLDs. Subsequent chapters address the pathogenic mechanisms underlying pulmonary cyst formation and provide a detailed overview of the radiological and pathological features of DCLDs. The common as well as uncommon causes of DCLDs are comprehensively reviewed in individual chapters, as are the varied clinical presentations and extrapulmonary manifestations, and approaches to management and treatment. The book culminates in a final chapter that presents a practical algorithmic approach to diagnosis that progresses from least invasive to most invasive approaches. This textbook provides a one-stop, comprehensive and integrated, clinical, radiologic, and pathologic overview of DCLDs that will be as useful to the practicing clinician as it is to the clinical investigator.

Orphan Lung Diseases

Author : J-F. Cordier
Publisher : European Respiratory Society
ISBN 13 : 1849840148
Total Pages : 376 pages
Book Rating : 4.8/5 (498 download)

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Book Synopsis Orphan Lung Diseases by : J-F. Cordier

Download or read book Orphan Lung Diseases written by J-F. Cordier and published by European Respiratory Society. This book was released on 2011-12-01 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been replaced by "Rare Diseases of the Respiratory System", ISBN 978-1-84984-167-2 A respiratory physician is only likely to see a few orphan lung diseases each year or even during their career. However, it is essential that specialists are able identify, confirm and diagnosis orphan lung disease in a patient. This Monograph comprehensively covers the most common and/or complex orphan lung diseases. It should be seen as a solid companion to the respiratory specialist each time they need to consider a diagnosis of an orphan disease.

Rare and Interstitial Lung Diseases

Author : Claudio Sorino
Publisher : Elsevier Health Sciences
ISBN 13 : 0323935311
Total Pages : 287 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Rare and Interstitial Lung Diseases by : Claudio Sorino

Download or read book Rare and Interstitial Lung Diseases written by Claudio Sorino and published by Elsevier Health Sciences. This book was released on 2024-02-16 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by global leaders in this challenging field, Rare and Interstitial Lung Diseases: Clinical Cases and Real-World Discussions brings you up to date with the latest advances in complex or rare lung diseases managed on outpatient or inpatient respiratory or critical care units. Using a unique, case-based approach, a wide variety of cases are presented along with perspectives from a multidisciplinary team of experts who discuss therapeutic choices and rationales. This real-world approach allows the reader to become a virtual attending physician, simulating a realistic clinical reasoning process on the diagnosis, treatment, and follow-up of patients with rare and complex lung diseases. Reflects a nuanced, multidisciplinary, evidence-based approach to diagnoses, treatment options, and follow-up criteria for complex and rare pulmonary disorders such as idiopathic pulmonary fibrosis, interstitial lung disease related to connective tissue diseases, hypersensitivity pneumonitis, sarcoidosis, and pulmonary vascular disease. Each case includes onset of symptoms, diagnostic/therapeutic path, and discussions on the clinical choices made in accordance with evidence-based medical procedures. Describes each clinical and laboratory finding and features 150 images, including plain film, procedural photos, ultrasound images, CT scans, and histopathology specimens. Includes the most recent updates to international guidelines (ATS/ERS/JRS/ALAT) on idiopathic pulmonary fibrosis (IPF). Covers the progression of pulmonary fibrosis in patients with ILD other than IPF; the role of transbronchial lung cryobiopsy (TBLC) in obtaining a tissue diagnosis in patients with undiagnosed ILD; and the indications of antifibrosant drugs. A practical and interactive resource for pulmonologists, as well as critical care and internal medicine practitioners and fellows, thoracic surgeons, and thoracic radiologists. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Interstitial Lung Diseases in Children

Author : Lourdes R. Laraya-Cuasay
Publisher : CRC Press
ISBN 13 : 1000012565
Total Pages : 282 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Interstitial Lung Diseases in Children by : Lourdes R. Laraya-Cuasay

Download or read book Interstitial Lung Diseases in Children written by Lourdes R. Laraya-Cuasay and published by CRC Press. This book was released on 2019-06-04 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1988, Interstitial Lung Diseases in Children identifies, describes and offers insight into how to treat the vast array of lung diseases found in infants, children, and teenagers. Filled with clear and useful references, this book works best as a guide for Pediatricians and those with a keen interest in Medicine.

Rare and Interesting Cases in Pulmonary Medicine

Author : Ali Ataya
Publisher : Academic Press
ISBN 13 : 0128097671
Total Pages : 246 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Rare and Interesting Cases in Pulmonary Medicine by : Ali Ataya

Download or read book Rare and Interesting Cases in Pulmonary Medicine written by Ali Ataya and published by Academic Press. This book was released on 2017-02-01 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rare and Interesting Cases in Pulmonary Medicine provides a look into the uncommon diseases encountered in the field of pulmonary medicine. Using a case-based approach, the book provides clinical scenarios that include relevant accompanying radiology and pathology. Also included are frequently asked questions for each area, as well as a diagnosis and summary, presenting the reader with the most high yield information on each topic. Appropriate for medical students, residents, fellows, and physicians interested in pulmonary medicine, the case-based approach to each topic allows accessibility to the uncommon diseases of the field while also highlighting high yield and important points. Provides case-based approaches to the uncommon diseases of pulmonary medicine, including supporting radiology and pathology Includes uncommon case studies, providing relevant references for further reading and research opportunities Presents related topics with accompanying clinical pearls for direct application in the field

Difficult to Diagnose Rare Diffuse Lung Disease

Author : Alexander V. Averyanov
Publisher : Academic Press
ISBN 13 : 0128153768
Total Pages : 430 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Difficult to Diagnose Rare Diffuse Lung Disease by : Alexander V. Averyanov

Download or read book Difficult to Diagnose Rare Diffuse Lung Disease written by Alexander V. Averyanov and published by Academic Press. This book was released on 2019-08-24 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Difficult to Diagnose Rare Diffuse Lung Disease presents the theoretical basis and practical aspects of differential diagnoses of rare lung diseases with the use of new method of probe-based confocal laser endomicroscopy (alveoscopy) of the distal respiratory region. Each chapter describes signs and symptoms of the disease and its typical and atypical manifestations. The book contains full color illustrations, including high-resolution histological microphotographs, CT-scans and confocal laser endomicroscopy images. In combination, these elements make this book an invaluable reference and guide for pulmonary researchers, pulmonologists, radiologists, and pathologists who wish to broaden their spectrum of knowledge in rare lung diseases. Highlights the new method of probe-based confocal laser endomicroscopy (alveoscopy) of the distal respiratory region, opening new horizons in the minimally invasive diagnosis of lung diseases Discusses current treatment strategies in accordance with clinical guidelines, including data from the latest clinical trials Presented in tabular format to aid in the diagnostic process

Cystic Fibrosis

Author : Prashant Mohite
Publisher : BoD – Books on Demand
ISBN 13 : 1838810730
Total Pages : 126 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Cystic Fibrosis by : Prashant Mohite

Download or read book Cystic Fibrosis written by Prashant Mohite and published by BoD – Books on Demand. This book was released on 2021-06-09 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cystic fibrosis, a genetic disorder in children and young adults, is a multisystemic disease that mainly affects the lungs. Advances and improvements in the diagnosis and management of this condition have led to increased overall and symptom-free survival in cystic fibrosis patients. This book examines recent advances in the field and presents an evidence-based approach to the management of cystic fibrosis.

Rare and Orphan Lung Diseases, An Issue of Clinics in Chest Medicine, E-Book

Author : Robert Kotloff
Publisher : Elsevier Health Sciences
ISBN 13 : 032346274X
Total Pages : 409 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Rare and Orphan Lung Diseases, An Issue of Clinics in Chest Medicine, E-Book by : Robert Kotloff

Download or read book Rare and Orphan Lung Diseases, An Issue of Clinics in Chest Medicine, E-Book written by Robert Kotloff and published by Elsevier Health Sciences. This book was released on 2016-08-16 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs. Robert Kotloff and Francis McCormack have assembled an expert team of authors on the topic of Rare and Orphan Lung Diseases. Articles include: Lymphangioleiomyomatosis, Pulmonary Lymphangiomatosis, Langerhans Cell Histiocytosis and other Histiocytic Diseases of the Lung, Pulmonary Alveolar Proteinosis, Pulmonary Alveolar Microlithiasis, Primary Ciliary Dyskinesia, Birt-Hogg-Dube Syndrome, Hermansky-Pudlak Syndrome, Hereditary Hemorrhagic Telangiectasia, Non-CF Bronchiectasis, Eosinophilic Lung Diseases, Benign Metastasizing Leiomyomata, and more!

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Author : Venkataramana K Sidhaye
Publisher : Academic Press
ISBN 13 : 0128038810
Total Pages : 277 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease by : Venkataramana K Sidhaye

Download or read book Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease written by Venkataramana K Sidhaye and published by Academic Press. This book was released on 2017-03-09 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences

Disease Control Priorities, Third Edition (Volume 5)

Author : Dorairaj Prabhakaran
Publisher : World Bank Publications
ISBN 13 : 1464805202
Total Pages : 948 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 5) by : Dorairaj Prabhakaran

Download or read book Disease Control Priorities, Third Edition (Volume 5) written by Dorairaj Prabhakaran and published by World Bank Publications. This book was released on 2017-11-17 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Cystic Fibrosis Gene

Author : Joe Smith
Publisher : Independently Published
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.3/5 (276 download)

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Book Synopsis Cystic Fibrosis Gene by : Joe Smith

Download or read book Cystic Fibrosis Gene written by Joe Smith and published by Independently Published. This book was released on 2024-06-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cystic fibrosis (CF) is a genetic disorder that affects the lungs, pancreas, and other organs. It is a life-threatening condition that primarily affects the respiratory and digestive systems, leading to progressive lung damage, difficulty breathing, and malnutrition. CF is a relatively rare disease, with approximately 30,000 people living with the condition in the United States and about 70,000 people worldwide. The first recorded case of cystic fibrosis was in 1938, when Dr. Dorothy Anderson identified it as a distinct medical condition. However, it was not until the 1950s that researchers began to understand the cause of CF - a faulty gene known as the cystic fibrosis transmembrane conductance regulator (CFTR). This gene is responsible for creating a protein that regulates the movement of salt and water in and out of cells. In a person with CF, this protein does not function properly, causing a build-up of thick, sticky mucus in the lungs and other organs. The mucus traps bacteria and other foreign particles, leading to frequent respiratory infections and difficulty breathing. In the pancreas, the mucus obstructs the normal function of the organ, preventing the release of enzymes needed for proper digestion and absorption of nutrients. This results in malnutrition and growth issues in individuals with CF. CF is an autosomal recessive disorder, meaning that both parents must carry a mutated copy of the CFTR gene for a child to inherit the condition. If both parents are carriers, there is a 25% chance of having a child with CF.

How Tobacco Smoke Causes Disease

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.