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Transporting Epithelia
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Book Synopsis Transporting Epithelia by : Michael Berridge
Download or read book Transporting Epithelia written by Michael Berridge and published by Elsevier. This book was released on 2012-12-02 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transporting Epithelia summarizes the progress that has been made in understanding a wide range of epithelial transport systems. This book discusses the epithelia involved in osmotic and ionic regulation from protonephridia to the mammalian kidney. It also explains the digestive and absorptive epithelia, as well as the epithelia that produce special secretions, such as milk, endolymph, aqueous humor, cerebrospinal fluid, sweat, and tears. Furthermore, this book describes the role of the epithelium in the physiology of the animal and the structure of the epithelium. Then, the structure of the epithelium is correlated with its physiological properties. This book will be valuable both for teaching and as a reference for research workers interested in comparative aspects of transport phenomena.
Book Synopsis Epithelial Transport by : N.K. Wills
Download or read book Epithelial Transport written by N.K. Wills and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building from general principles, the authors clearly explain the fundamental role of epithelia in plasma electrolyte and water balance. Emphasis is placed on experimental approaches and methodology. A comprehensive glossary of terms is included.
Book Synopsis Epithelial Transport Physiology by : George A. Gerencser
Download or read book Epithelial Transport Physiology written by George A. Gerencser and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological cell membranes regulate the transfer of matter and information between the intracellular and extracellular compartments as basic survival and maintenance functions for an organism. This volume contains a series of reviews that are c- cerned with how epithelial plasma membranes regulate the transport of solutes between the intracellular and extracellular compartments of a cell. This book is also an attempt to analyze the molecular basis for the movement of various solutes across an epithelial cell membrane. This volume is devoted to a diversity of epithelial transport mechanisms in rep- sentative cell membranes of a variety of living things. The ?rst section of the book (Chapters 1–6) focuses on mechanisms of solute transport in epithelia of inver- brates. The last section which comprises ten chapters (Chapters 7–16) deals with solute transporters in epithelial cell membranes of vertebrates. It is hoped that with this particular ordering the reader can glean a telescopic view of the evolutionary history of the various epithelial solute transporters.
Book Synopsis Basic Epithelial Ion Transport Principles and Function by : Kirk L. Hamilton
Download or read book Basic Epithelial Ion Transport Principles and Function written by Kirk L. Hamilton and published by Springer Nature. This book was released on 2020-11-26 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike.
Book Synopsis NaCl Transport in Epithelia by : R. Greger
Download or read book NaCl Transport in Epithelia written by R. Greger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way. The first phase of the phenomenological description of the cell as a black box has been follow ed by studies of cellular mechanisms, the interplay of the different trans port components, and the mechanisms of regulation. A broad spectrum of methods has been applied to many epithelia in a variety of species. For the individual epithelia transport schemes have been proposed, and, at this point I think it is appropriate to take a pause and search for elements common to several epithelia. This aspect triggered the publica tion of this book, and in fact the various chapters emphasize that the funetional eomponents, expressed in the various epithelia, are not in finite in number, but they occur in epithelia which are separated in evolu tion by several hundred million years. The authors come both from the field of veterinary and human physiology as weIl as from biology. In my opinion, the close contacts and eollaborations between physiologists and biologists have been essential for the progress in this field. I wish to thank all authors for their con tributions, and I hope that the reader will appreciate this collection of up to date reviews on epithelia in nonvertebrates and vertebrates.
Book Synopsis Studies of Epithelial Transporters and Ion Channels by : Kirk L. Hamilton
Download or read book Studies of Epithelial Transporters and Ion Channels written by Kirk L. Hamilton and published by Springer Nature. This book was released on 2021-03-04 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. The focus of this volume lies with different ion channel and transporter families. Additionally, this volume benefits from pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual epithelial ion channels and transporters from the 1st Edition, along with eleven new chapters. That makes Volume 3 an insightful contribution for physiology students, scientists and clinicians.
Download or read book Epithelia written by C.J. Jones and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epithelial cells probably constitute the most diverse group of cells found in the body. In addition to serving as interfaces between external and internal environments, their functions include ion and fluid secretion and reabsorp tion, protein exocytosis, hormone secretion, recognition, surface protection and the control of ciliary movement. By their very exposure on the surfaces of the body, epithelial cells are subjected to wide-ranging assault, by micro organisms and by chemical and physical forces. They are the targets for abrasion, infection and malignant transformation. Some epithelial cells show altered behaviour in inherited syndromes, such as cystic fibrosis, characterized by serious pancreatic and pulmonary disease. In view of the importance of epithelia and the fact that their function can be altered by environmental and inherited factors, they are the subject of intensive research, particularly so in the case of cancer where most tumours are of epithelial origin. The use of animal tissues in epithelial research continues to provide important advances and this, coupled with the need to focus more on human tissues, has prompted a greater research emphasis on accessible human epithelia and on the establishment of cell cultures from animal and human sources. For primary cell cultures and cell lines to be of value, they need to express properties appropriate to their progenitors and relevant to the study in progress.
Book Synopsis Ion Channels and Transporters of Epithelia in Health and Disease by : Kirk L. Hamilton
Download or read book Ion Channels and Transporters of Epithelia in Health and Disease written by Kirk L. Hamilton and published by Springer. This book was released on 2015-12-14 with total page 1015 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.
Book Synopsis Ion Transport by Epithelia by : Stanley G. Schultz
Download or read book Ion Transport by Epithelia written by Stanley G. Schultz and published by Raven Press (ID). This book was released on 1981 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Introduction to Cellular Biophysics, Volume 2 by : Armin Kargol
Download or read book Introduction to Cellular Biophysics, Volume 2 written by Armin Kargol and published by Morgan & Claypool Publishers. This book was released on 2019-12-13 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What the cells consists of? Where are its organelles? What function each organelle fulfils? From a chemists’ point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, some of the fundamental questions are about the physical movement of all these molecules between organelles within the cell, their exchange with the extracellular medium, as well as electrical phenomena resulting from such transport. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and various electrical effects, and that in turn leads to biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfill its function as a part of a larger organ or organism. The first volume of this book is an inventory of physical transport processes occurring in cells while this second volume provides a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.
Book Synopsis Transport Mechanisms in Epithelia by : Hans H. Ussing
Download or read book Transport Mechanisms in Epithelia written by Hans H. Ussing and published by . This book was released on 1973 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Epithelial Anion Transport in Health and Disease by : Derek J. Chadwick
Download or read book Epithelial Anion Transport in Health and Disease written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2006-07-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear that the SLC26 transporters have broad physiological functions since mutations in several members are linked to a variety of diseases. This book describes the properties of this family in detail, with contributions from the leading global researchers in the field. Complementary views from experts on other ion channels are offered in the discussions, which make fascinating reading. This family consists of at least 10 genes, each of which has several splice variants. Most members of the family are expressed in the luminal membrane of epithelial cells. Characterization of anion transport by three members has revealed that all function as Cl-/HCO3- exchangers, suggesting that SLC26 transporters are responsible for the luminal Cl-/HCO3- exchange activity. The SLC26 transporters are activated by the CF transmembrane conductance regulator and activate it in turn, leading to a model in which these molecules act together to mediate epithelial Cl- absorption and HCO3- secretion. The book includes chapters on the transport of other molecules by the SLC26 family, including oxalate in the kidney and sugars in cochlear hair cells amongst others. It also describes recent discoveries that most SLC26 transporters bind to scaffold proteins and that they all contain a conserved domain predicted to participate in protein-protein interactions. These suggest the SLC26 transporters exist in complexes with other Cl- and HCO3- transporters, and possibly other regulatory proteins. This book explores the functional role of these interactions, leading to better understanding of transepithelial fluid and electrolyte secretion and the diseases associated with it.
Book Synopsis Water Transport Across Epithelia by : Hans H. Ussing
Download or read book Water Transport Across Epithelia written by Hans H. Ussing and published by Nankodo Company, Limited. This book was released on 1981 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NaCl Transport in Epithelia by : R. Greger
Download or read book NaCl Transport in Epithelia written by R. Greger and published by Springer. This book was released on 1988-05-30 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way. The first phase of the phenomenological description of the cell as a black box has been follow ed by studies of cellular mechanisms, the interplay of the different trans port components, and the mechanisms of regulation. A broad spectrum of methods has been applied to many epithelia in a variety of species. For the individual epithelia transport schemes have been proposed, and, at this point I think it is appropriate to take a pause and search for elements common to several epithelia. This aspect triggered the publica tion of this book, and in fact the various chapters emphasize that the funetional eomponents, expressed in the various epithelia, are not in finite in number, but they occur in epithelia which are separated in evolu tion by several hundred million years. The authors come both from the field of veterinary and human physiology as weIl as from biology. In my opinion, the close contacts and eollaborations between physiologists and biologists have been essential for the progress in this field. I wish to thank all authors for their con tributions, and I hope that the reader will appreciate this collection of up to date reviews on epithelia in nonvertebrates and vertebrates.
Book Synopsis Epithelial Ion and Water Transport by : Anthony D. C. Macknight
Download or read book Epithelial Ion and Water Transport written by Anthony D. C. Macknight and published by Raven Press (ID). This book was released on 1981 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transporting Epithelia by : Michael J. Berridge
Download or read book Transporting Epithelia written by Michael J. Berridge and published by . This book was released on 1972 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Epithelial Transport Physiology by :
Download or read book Epithelial Transport Physiology written by and published by . This book was released on 2011-07 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: