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Author : Maria Teresa Pérez-Gracia
Publisher : Frontiers Media SA
ISBN 13 : 2889743373
Total Pages : 104 pages
Book Rating : 4.8/5 (897 download)
Download or read book Translational Research in Hepatitis E written by Maria Teresa Pérez-Gracia and published by Frontiers Media SA. This book was released on 2022-02-04 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Helga Rübsamen-Schaeff
Publisher : John Wiley & Sons
ISBN 13 : 3527810706
Total Pages : 530 pages
Book Rating : 4.5/5 (278 download)
Download or read book New Drug Development for Known and Emerging Viruses written by Helga Rübsamen-Schaeff and published by John Wiley & Sons. This book was released on 2021-11-30 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the ;pharmaceutical industry and public health agencies.
Author : Manja Marz
Publisher : MDPI
ISBN 13 : 3039218824
Total Pages : 330 pages
Book Rating : 4.0/5 (392 download)
Download or read book Virus Bioinformatics written by Manja Marz and published by MDPI. This book was released on 2020-02-21 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309438020
Total Pages : 187 pages
Book Rating : 4.3/5 (94 download)
Download or read book Eliminating the Public Health Problem of Hepatitis B and C in the United States written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-06-01 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.
Author : Sofie J. S. Bekaert
Publisher : Frontiers Media SA
ISBN 13 : 2889660168
Total Pages : 109 pages
Book Rating : 4.8/5 (896 download)
Download or read book Biobanks as Essential Tools for Translational Research: The Belgian Landscape written by Sofie J. S. Bekaert and published by Frontiers Media SA. This book was released on 2020-09-17 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Stanley M. Lemon
Publisher : Perspectives Cshl
ISBN 13 : 9781621821625
Total Pages : 400 pages
Book Rating : 4.8/5 (216 download)
Download or read book Enteric Hepatitis Viruses written by Stanley M. Lemon and published by Perspectives Cshl. This book was released on 2018 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from Cold Spring Harbor Perspectives in Medicine"--title page.
Author : Frederick J. Suchy
Publisher : Cambridge University Press
ISBN 13 : 1139464035
Total Pages : 995 pages
Book Rating : 4.1/5 (394 download)
Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2007-05-07 with total page 995 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.
Author : Irwin M. Arias
Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)
Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.
Author : Franco Maria Ruggeri
Publisher : Springer Science & Business Media
ISBN 13 : 1461475228
Total Pages : 89 pages
Book Rating : 4.4/5 (614 download)
Download or read book Hepatitis E Virus written by Franco Maria Ruggeri and published by Springer Science & Business Media. This book was released on 2013-06-06 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis E (HEV) is a viral infectious disease that infects humans and domestic, wild, and synanthropic animals alike. In developing countries, the disease often presents as an epidemic, transmitted primarily through the fecal-oral route. In recent years, sporadic cases have also been documented in industrial countries, including Europe. The identification and characterization of animal strains of HEV from pigs, wild boar, and deer, and the demonstrated ability of cross-species infection by these animal strains raise potential public health concerns for foodborne and zoonotic transmission of the virus. This Brief will provide a thorough overview of HEV. It will discuss the epidemiology and pathogenesis of the virus in both humans and animals, review detection methods, and provide methods for its control and prevention.
Author : W. Michael Scheld
Publisher : American Society for Microbiology Press
ISBN 13 : 1555815251
Total Pages : 527 pages
Book Rating : 4.5/5 (558 download)
Download or read book Emerging Infections 9 written by W. Michael Scheld and published by American Society for Microbiology Press. This book was released on 2010-09-02 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the recent Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America sessions. • Focuses on a broad range of infectious agents that pose challenges for the clinical, laboratory, research, public health, and animal health communities. • Reflects the diversity of infectious agent threats in the 21st century. Some of these agents have been only recently discovered, such as the Acanthamoeba polyphaga mimivirus. Others are known pathogens presenting new challenges, such as human adenovirus 14.
Author : Roger Detels
Publisher : Oxford University Press
ISBN 13 : 019881013X
Total Pages : 1717 pages
Book Rating : 4.1/5 (988 download)
Download or read book Oxford Textbook of Global Public Health written by Roger Detels and published by Oxford University Press. This book was released on 2017 with total page 1717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline
Author : John L. Casey
Publisher : Springer
ISBN 13 : 9783642067518
Total Pages : 0 pages
Book Rating : 4.0/5 (675 download)
Download or read book Hepatitis Delta Virus written by John L. Casey and published by Springer. This book was released on 2010-02-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis delta virus (HDV), which causes severe acute and chronic liver disease, was discovered nearly 30 years ago following the detection of a novel antigen-antibody system in hepatitis B virus carriers. HDV has continued to surprise and fascinate medical science ever since. This volume reviews recent developments in HDV research, from molecular virology to genetics to experimental investigation of new therapeutic and vaccine candidates.
Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 290 pages
Book Rating : 4.1/5 (281 download)
Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Author : Haitao Guo
Publisher : Springer Nature
ISBN 13 : 1071640275
Total Pages : 278 pages
Book Rating : 4.0/5 (716 download)
Download or read book Hepatitis B Virus written by Haitao Guo and published by Springer Nature. This book was released on with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John A. J. Barbara
Publisher : Cambridge University Press
ISBN 13 : 0521453933
Total Pages : 0 pages
Book Rating : 4.5/5 (214 download)
Download or read book Transfusion Microbiology written by John A. J. Barbara and published by Cambridge University Press. This book was released on 2008-04-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive resource for all practitioners and researchers involved in transfusion medicine.
Author : M. P. G. Koopmans
Publisher :
ISBN 13 : 9781628702248
Total Pages : 245 pages
Book Rating : 4.7/5 (22 download)
Download or read book Food-borne Viruses written by M. P. G. Koopmans and published by . This book was released on 2008 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food-borne viruses are recognized as a major health concern, but their distribution, definition, and impact are poorly understood. The volume Food-Borne Viruses goes a long way in correcting that problem. Written by leading scientists in the field, it brings together the latest knowledge on these viral strains, their detection and control, and associated challenges.
Author : Tim F. Greten
Publisher : Springer
ISBN 13 : 9783319879116
Total Pages : 0 pages
Book Rating : 4.8/5 (791 download)
Download or read book Immunotherapy of Hepatocellular Carcinoma written by Tim F. Greten and published by Springer. This book was released on 2018-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.
