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Translational Research In Cancer
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Book Synopsis Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics by : Erika Ruiz-Garcia
Download or read book Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics written by Erika Ruiz-Garcia and published by Springer Nature. This book was released on 2019-11-11 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.
Book Synopsis Translational Research in Breast Cancer by : Dong-Young Noh
Download or read book Translational Research in Breast Cancer written by Dong-Young Noh and published by Springer Nature. This book was released on 2021-05-13 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.
Book Synopsis Targeted Therapy in Translational Cancer Research by : Apostolia-Maria Tsimberidou
Download or read book Targeted Therapy in Translational Cancer Research written by Apostolia-Maria Tsimberidou and published by John Wiley & Sons. This book was released on 2015-12-21 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities
Book Synopsis Translational Research in Cancer by : Sivapatham Sundaresan
Download or read book Translational Research in Cancer written by Sivapatham Sundaresan and published by BoD – Books on Demand. This book was released on 2021-02-03 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies concerning the molecular pathways involved in tumorigenesis. Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Experimental cancer treatments are studied in clinical trials to compare the proposed treatment to the best existing treatment through translational research. The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis) 2) Translational perspective on hepatocellular carcinoma 3) Brachytherapy for endometrial cancer 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer
Book Synopsis Immunotherapy in Translational Cancer Research by : Laurence J. N. Cooper
Download or read book Immunotherapy in Translational Cancer Research written by Laurence J. N. Cooper and published by John Wiley & Sons. This book was released on 2018-05-01 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues. Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.
Book Synopsis The Comprehensive Cancer Center by : Mahmoud Aljurf
Download or read book The Comprehensive Cancer Center written by Mahmoud Aljurf and published by Springer Nature. This book was released on 2021-10-28 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a valuable resource for hospitals, institutions, and health authorities worldwide in their plans to set up and develop comprehensive cancer care centers. The development and implementation of a comprehensive cancer program allows for a systematic approach to evidence-based strategies of prevention, early detection, diagnosis, treatment, and palliation. Comprehensive cancer programs also provide a nexus for the running of clinical trials and implementation of novel cancer therapies with the overall aim of optimizing comprehensive and holistic care of cancer patients and providing them with the best opportunity to improve quality of life and overall survival. This book's self-contained chapter format aims to reinforce the critical importance of comprehensive cancer care centers while providing a practical guide for the essential components needed to achieve them, such as operational considerations, guidelines for best clinical inpatient and outpatient care, and research and quality management structures. Intended to be wide-ranging and applicable at a global level for both high and low income countries, this book is also instructive for regions with limited resources. The Comprehensive Cancer Center: Development, Integration, and Implementation is an essential resource for oncology physicians including hematologists, medical oncologists, radiation oncologists, surgical oncologists, and oncology nurses as well as hospitals, health departments, university authorities, governments and legislators.
Book Synopsis Lost in Translation by : Rakesh K. Srivastava
Download or read book Lost in Translation written by Rakesh K. Srivastava and published by World Scientific. This book was released on 2014 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an effort to bring together scientists active in various areas of translational research to share science and, hopefully, generate new ideas and potential collaborations. The book provides a comprehensive overview of translational work that includes significant discoveries and pioneering contributions, e.g., in immunology, gene therapy, stem cells and population sciences. It may be used as an advanced textbook by graduate students and even ambitious undergraduates in biomedical sciences. It is also suitable for non-experts, i.e. medical doctors, who wish to have an overview of some of the fundamental models in translational research. Managing the translational enterprise remains a work in progress. The world is changing rapidly, and the scientific world needs to seek new ways to ensure that discoveries get translated for patients efficiently and as quickly as possible. In addition, everyone expects the investment in biomedical research should pay dividends through effective therapeutic solutions. This unique project provides a broad collaborative approach of the international scientific team to present its view and opinion how to cross barriers to incentives for translational research in medical sciences. Contributing to the book is an international team of prominent co-authors. The book consists of unique and widely treated topics, and includes new hypotheses, data and analyses. Sample Chapter(s). Foreword (41 KB). Chapter 1: Translational Research: Lost in Complexity (305 KB). Contents: Barriers to Incentives for Translational Research; Integrating Emerging Science into Clinical Practice; Organization, Prioritization, Review and Funding for the Translational Research; Translational Sciences in Cancer Research; Translational Science in Infectious Diseases; Translation Research in Endocrinology and Nutrition; Translation Research and Neuroscience; Stem Cells and Translation Research; The Role of Translational Research in Public Health and Behavioral Sciences; Translational Epidemiology, Biostatistics and Informatics; Translational Research Outcomes and Resources. Readership: Graduate students and researchers in cancer research, pharmacology/drug discovery/pharmaceuticals, immunology, infectious diseases and public health.
Book Synopsis Principles of Translational Science in Medicine by : Martin Wehling
Download or read book Principles of Translational Science in Medicine written by Martin Wehling and published by Academic Press. This book was released on 2015-04-02 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies Details IPR issues of translation, especially for public-private-partnerships Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions
Book Synopsis Translational Research in Breast Cancer by : Erwei Song
Download or read book Translational Research in Breast Cancer written by Erwei Song and published by Springer. This book was released on 2017-12-28 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer. With the latest developments in breast cancer research, our understanding of the genomic changes and the oncogenic signaling cascade of breast cancer has made considerable strides. Further, the immuno-environment has been demonstrated as the barrier to clinical cancer. In addition, major advances in cancer biology, immunology, genomics and metabolism have broken new ground for designing therapeutic approaches and selecting appropriate treatments on the basis of more precise information on the individual patient. As a result of these two trends, a clearer picture of the molecular landscape of breast cancers has facilitated the development of diagnostic, prognostic and predictive biomarkers for clinical oncology. All these aspects are addressed in this volume, which offers a comprehensive resource for researchers, graduate students and oncologists in cancer research.
Book Synopsis Translational Cancer Research for Surgeons, An Issue of Surgical Oncology Clinics by : William G. Cance
Download or read book Translational Cancer Research for Surgeons, An Issue of Surgical Oncology Clinics written by William G. Cance and published by Elsevier Health Sciences. This book was released on 2013-09-19 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. William G. Cance, is devoted to Translational Cancer Research for Surgeons. Translational Cancer research aims to move bench research to the bedside by applying basic science toward potential therapies. This issue will present the concepts of translational research and development of targeted therapeutics, and its implications for surgeons. It will show clinical applications for surgeons regarding sarcoma/GIST, melanoma, colorectal cancer, breast cancer, and endocrine cancer.
Book Synopsis Translational Research in Thyroid Cancer by : Vasyl Vasko
Download or read book Translational Research in Thyroid Cancer written by Vasyl Vasko and published by Frontiers Media SA. This book was released on 2020-06-05 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Combinatorial Approaches for Cancer Treatment: from Basic to Translational Research by : Daniela Spano
Download or read book Combinatorial Approaches for Cancer Treatment: from Basic to Translational Research written by Daniela Spano and published by Frontiers Media SA. This book was released on 2022-03-03 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Translational Radiation Oncology by : Adam Eltorai
Download or read book Translational Radiation Oncology written by Adam Eltorai and published by Elsevier. This book was released on 2023-08-01 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Radiation Oncology covers the principles of evidence-based medicine and applies them to the design of translational research. The book provides valuable discussions on the critical appraisal of published studies and recent developments in radiation oncology, allowing readers to learn how to evaluate the quality of such studies with respect to measuring outcomes and make effective use of all types of evidence. By reading this book, researchers have access to a practical approach to help them navigate challenging considerations in study design and implementation. It is a valuable resource for researchers, oncologists and members of biomedical field who want to understand more about translational research applied to the field of radiation oncology. Translational medicine serves as an indispensable tool in grant writing and funding efforts, so understanding how to apply its principles to research is necessary to guarantee that results will be impactful to patients. Provides a clear process for understanding, designing, executing and analyzing clinical and translational research Presents practical, step-by-step guidance to help readers take ideas from the lab to the bedside Written by a team of oncologists, radiologists and clinical research experts that fully cover translational research in radiation oncology
Book Synopsis Translational Pain Research by : Lawrence Kruger
Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical
Book Synopsis Perspectives in Cancer Prevention-Translational Cancer Research by : Perumana R. Sudhakaran
Download or read book Perspectives in Cancer Prevention-Translational Cancer Research written by Perumana R. Sudhakaran and published by Springer. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory or population studies into clinical application to reduce incidence of cancer , morbidity and mortality. It is becoming increasingly evident that cancer is a preventable disease. The IVth International Symposium on Translational Cancer Research held in Udaipur, India in December 2011, discussed various aspects of the biological processes in cancer cells and approaches to cancer prevention. A few contributions from this meeting are presented in this book, providing an in depth analysis of data on cancer prevention and therapeutics. These contributions are either critical reviews or research reports. The topics discussed include evidence-based nutritional recommendations for cancer patients and survivors, risk factors such as stress, enrichment of tumour stem cells by anticancer drug treatment contributing to tumour recurrence and the mechanism of anticancer effects of various natural products. Chemosensitizing effect of curcumin, anti-cancer effect of products from neem, action of sulforaphane and cytotoxic effect of a number of novel synthetic coordination complexes of trace metals have been discussed. Novel molecular targets of angiogenesis and molecular basis of the gender bias to thyroid cancer have also been discussed . This book provides useful information on translational cancer research to clinicians and biomedical scientists.
Book Synopsis ESMO Handbook on Principles of Translational Research by : Håkan Mellstedt
Download or read book ESMO Handbook on Principles of Translational Research written by Håkan Mellstedt and published by CRC Press. This book was released on 2007-05-21 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using state-of-the-art and evidence-based literature references and reviews, the authors present an overview of translational research that is both reliable and easily understood. The book begins with principles of normal cell biology and normal immunology. It examines tumor biology and basic tumor immunology. It then discusses limitless replicativ
Book Synopsis Oxford Handbook of Palliative Care by : Max Watson
Download or read book Oxford Handbook of Palliative Care written by Max Watson and published by Oxford University Press. This book was released on 2009-03-26 with total page 1078 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised throughout with an additional emphasis on nursing care, this handbook is a concise and authoritative guide to modern palliative care. An ideal resource for the busy professional management of patients with end of life care needs.