Translational Neuroimmunology In Multiple Sclerosis

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Translational Neuroimmunology in Multiple Sclerosis

Author : Ruth Arnon
Publisher : Academic Press
ISBN 13 : 0128020075
Total Pages : 504 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Translational Neuroimmunology in Multiple Sclerosis by : Ruth Arnon

Download or read book Translational Neuroimmunology in Multiple Sclerosis written by Ruth Arnon and published by Academic Press. This book was released on 2016-05-10 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development. - Provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis and the translation of this research to immunotherapy treatment - Edited by renowned leaders in the field of neuroimmunology and multiple sclerosis - Contains the latest resource material for basic and clinical scientists and practitioners in neuroscience, neurology, immunology, and pharmacology - 2017 BMA Medical Book Awards Highly Commended in Neurology

Translational Methods for Multiple Sclerosis Research

Author : Sergiu Groppa
Publisher : Humana
ISBN 13 : 9781071612125
Total Pages : 335 pages
Book Rating : 4.6/5 (121 download)

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Book Synopsis Translational Methods for Multiple Sclerosis Research by : Sergiu Groppa

Download or read book Translational Methods for Multiple Sclerosis Research written by Sergiu Groppa and published by Humana. This book was released on 2021-08-03 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements.

Conn's Translational Neuroscience

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 0128025964
Total Pages : 778 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Conn's Translational Neuroscience by : P. Michael Conn

Download or read book Conn's Translational Neuroscience written by P. Michael Conn and published by Academic Press. This book was released on 2016-09-28 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. - Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance - Features contributions from leading global basic and clinical investigators in the field - Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes - Relates and translates the current science to the understanding of neurological disorders and their treatment

Autoimmune Neurology

Author :
Publisher : Elsevier
ISBN 13 : 0444634460
Total Pages : 569 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Autoimmune Neurology by :

Download or read book Autoimmune Neurology written by and published by Elsevier. This book was released on 2016-03-11 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. - Includes comprehensive coverage of autoimmune neurology - Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders - Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Translational Neuroimmunology, Volume 8

Author : Nima Rezaei
Publisher : Elsevier
ISBN 13 : 0443185794
Total Pages : 272 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Translational Neuroimmunology, Volume 8 by : Nima Rezaei

Download or read book Translational Neuroimmunology, Volume 8 written by Nima Rezaei and published by Elsevier. This book was released on 2023-06-16 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research. - Provides an introduction on multiple sclerosis as an autoimmune disease, from bench to bedside - Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease - Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system - Shows the changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases

Neuroimmune Diseases

Author : Hiroshi Mitoma
Publisher : Springer
ISBN 13 : 3030195155
Total Pages : 822 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Neuroimmune Diseases by : Hiroshi Mitoma

Download or read book Neuroimmune Diseases written by Hiroshi Mitoma and published by Springer. This book was released on 2019-08-13 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases

Mayo Clinic Cases in Neuroimmunology

Author : Andrew McKeon
Publisher : Oxford University Press
ISBN 13 : 0197583423
Total Pages : 329 pages
Book Rating : 4.1/5 (975 download)

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Book Synopsis Mayo Clinic Cases in Neuroimmunology by : Andrew McKeon

Download or read book Mayo Clinic Cases in Neuroimmunology written by Andrew McKeon and published by Oxford University Press. This book was released on 2022-01-18 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mayo Clinic Cases in Neuroimmunology delivers a case-based walk-through of demyelinating, autoimmune, and other inflammatory neurologic disorders and their mimics. The authors present cases from their own extensive experience with common and rare neuroimmunologic disorders. The format of this case-based book was developed to stimulate consideration of the differential diagnosis as the reader reviews the history and examination narratives of each of the 83 cases. Videos of autoimmune movement disorders supplement the clinical descriptions, where pertinent. In addition, test results from radiology, electrophysiology, and laboratory studies are presented, and treatment and outcome data are also included. Clinical pearls and radiologic clues to assist informed diagnostic decision-making are emphasized. Each case is followed by discussion, including therapeutic guidance and key take-home points. More than 150 multiple-choice questions with answers are also given to test readers' comprehension and retention. This new addition to the Mayo Clinic Scientific Press series is a comprehensive volume on neuroimmunology that will stimulate and inform those aiming for clinical mastery.

Neurodegeneration in Multiple Sclerosis

Author : M. Filippi
Publisher : Springer Science & Business Media
ISBN 13 : 8847003911
Total Pages : 233 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Neurodegeneration in Multiple Sclerosis by : M. Filippi

Download or read book Neurodegeneration in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world-renowned scientists, the volume provides a state-of-the-art on the most recent MRI techniques related to MS, and it is an indispensable tool for all those working in this field. The context in which this book exists is that there is an increasing perception that modern MR methodologies should be more extensively employed in clinical trials to derive innovative information.

Neuroimmunology

Author : Amanda L. Piquet
Publisher : Springer Nature
ISBN 13 : 3030618838
Total Pages : 536 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Neuroimmunology by : Amanda L. Piquet

Download or read book Neuroimmunology written by Amanda L. Piquet and published by Springer Nature. This book was released on 2021-03-08 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentations in neuroimmunology, including pediatric demyelinating diseases. These sections provide practical clinical information to improve the reader’s knowledge in this complex field. The chapters are written by world renown authors with extensive knowledge to help provide up to date information. The full scope of autoimmune neurology is discussed, which is a unique feature of this book. Neuroimmunology serves as a resource for those in training including residents and fellows to provide clear clinical reasoning and background in a rapidly advancing field.

Neuroinflammation

Author : Samuel David
Publisher : John Wiley & Sons
ISBN 13 : 1118732820
Total Pages : 321 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Neuroinflammation by : Samuel David

Download or read book Neuroinflammation written by Samuel David and published by John Wiley & Sons. This book was released on 2015-05-26 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroinflammation has long been studied for its connection to the development and progression of Multiple Sclerosis. In recent years, the field has expanded to look at the role of inflammatory processes in a wide range of neurological conditions and cognitive disorders including stroke, amyotrophic lateral sclerosis, and autism. Researchers have also started to note the beneficial impacts of neuroinflammation in certain diseases. Neuroinflammation: New Insights into Beneficial and Detrimental Functions provides a comprehensive view of both the detriments and benefits of neuroinflammation in human health. Neuroinflammation: New Insights into Beneficial and Detrimental Functions opens with two chapters that look at some fundamental aspects of neuroinflammation in humans and rodents. The remainder of the book is divided into two sections which examine both the detrimental and beneficial aspects of inflammation on the brain, spinal cord and peripheral nerves, on various disease states, and in normal aging. These sections provide a broad picture of the role neuroinflammation plays in the physiology and pathology of various neurological disorders. Providing cross-disciplinary coverage, Neuroinflammation: New Insights into Beneficial and Detrimental Functions will be an essential volume for neuroimmunologists, neurobiologists, neurologists, and others interested in the field.

Multiple Sclerosis

Author : Flavia Nelson
Publisher : Cambridge University Press
ISBN 13 : 1108820751
Total Pages : 233 pages
Book Rating : 4.1/5 (88 download)

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Book Synopsis Multiple Sclerosis by : Flavia Nelson

Download or read book Multiple Sclerosis written by Flavia Nelson and published by Cambridge University Press. This book was released on 2021-02-04 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a practical and accessible approach to the diagnosis and management of multiple sclerosis in hospital and outpatient settings.

Update on Translational Neuroimmunology - Research of ISNI 2018

Author : Sandra Amor
Publisher : Frontiers Media SA
ISBN 13 : 2889662950
Total Pages : 253 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Update on Translational Neuroimmunology - Research of ISNI 2018 by : Sandra Amor

Download or read book Update on Translational Neuroimmunology - Research of ISNI 2018 written by Sandra Amor and published by Frontiers Media SA. This book was released on 2020-12-29 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 14th International Congress of Neuroimmunology, ISNI 2018, was held in August 2018 in Brisbane, Australia, and is a biennial event organized by the International Society of Neuroimmunology (ISNI). The theme of ISNI 2018 was “Travelling the Neuroimmunological Translational Highway”, and the Congress highlighted many research discoveries that bridge the gap between basic and clinical sciences, and which impact our understanding of pathogenic immune-mediated mechanisms in diseases affecting the nervous system. In this Research Topic, we aim to give a comprehensive overview of topics highlighted at the Congress, showcasing the current state of the field of neuroimmunology and where it is going in the near future.

Clinical Neuroimmunology

Author : Jack P. Antel
Publisher :
ISBN 13 : 0198510683
Total Pages : 467 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Clinical Neuroimmunology by : Jack P. Antel

Download or read book Clinical Neuroimmunology written by Jack P. Antel and published by . This book was released on 2005 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurimmunology is the major reference text in the field, providing broad and comprehensive coverage of the interaction between the nervous and immune systems in both normal and diseased states. Understanding this interaction is fundamental to developing therapeutic approaches to disease and injury of the nervous system that are currently only marginally amenable to therapy. Neuroimmunology is a well-recognised and growing specialty world wide, both at the basic science and clinical level. It is a fast moving field and this is the most up to date text available. Chapters are dedicated to the role of the immune system in disorders affecting both the central and peripheral nervous systems, including important neurodegenerative diseases (such as multiple sclerosis and HIV-related neural degeneration) which cause life-long disability. Extensive coverage is given to a whole array of immune-directed therapies. The book has a strong international team of well respected, high profile editors and authors. The first edition published to extensive and positive reviews and has established itself as the principal reference source in the field. This second edition summarizes recent advances in clinical neuroimmunology in a comprehensive and unbiased way.

Translational Neuroimmunology, Volume 7

Author : Nima Rezaei
Publisher : Elsevier
ISBN 13 : 0323900712
Total Pages : 542 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Translational Neuroimmunology, Volume 7 by : Nima Rezaei

Download or read book Translational Neuroimmunology, Volume 7 written by Nima Rezaei and published by Elsevier. This book was released on 2023-06-16 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders, with multiple sclerosis as the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in ten chapters. A chapter also examines distinct aspects of pericytes, with final discussions on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from translational research on non-human primates and zebrafish. All sections are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research. - Gives an introduction on neuroimmunological diseases, from bench to bedside - Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease - Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system - Proves changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases

Brain Neurotrauma

Author : Firas H. Kobeissy
Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Neuroinflammation

Author : Alireza Minagar
Publisher : Elsevier
ISBN 13 : 0123849144
Total Pages : 541 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Neuroinflammation by : Alireza Minagar

Download or read book Neuroinflammation written by Alireza Minagar and published by Elsevier. This book was released on 2010-12-17 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. - Comprehensive review of the latest developments in neuroinflammation - Includes contributions from leading authorities

Diseases of the Nervous System

Author : Harald Sontheimer
Publisher : Elsevier
ISBN 13 : 0128213965
Total Pages : 502 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Diseases of the Nervous System by : Harald Sontheimer

Download or read book Diseases of the Nervous System written by Harald Sontheimer and published by Elsevier. This book was released on 2021-05-20 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the brain continues to expand at a rapid pace providing fascinating insights into the basic mechanisms underlying nervous system illnesses. New tools, ranging from genome sequencing to non-invasive imaging, and research fueled by public and private investment in biomedical research has been transformative in our understanding of nervous system diseases and has led to an explosion of published primary research articles. Diseases of the Nervous System, Second Edition, summarizes the current state of basic and clinical knowledge for the most common neurological and neuropsychiatric conditions. In a systematic progression, each chapter covers either a single disease or a group of related disorders ranging from static insults to primary and secondary progressive neurodegenerative diseases, neurodevelopmental illnesses, illnesses resulting from nervous system infection and neuropsychiatric conditions. Chapters follow a common format and are stand-alone units, each covering disease history, clinical presentation, disease mechanisms and treatment protocols. Dr. Sontheimer also includes two chapters which discuss common concepts shared among the disorders and how new findings are being translated from the bench to the bedside. In a final chapter, he explains the most commonly used neuroscience jargon. The chapters address controversial issues in current day neuroscience research including translational research, drug discovery, ethical issues, and the promises of personalized medicine. This new edition features new chapters on Pain and Addiction to highlight the growing opioid crisis and the ethical issue of prescriptions drug abuse. This book provides an introduction for course adoption and an introductory tutorial for students, scholars, researchers and medical professionals interested in learning the state of the art concerning our understanding and treatment of diseases of the nervous system. Each chapter includes suggested further readings and/or journal club recommendations. - 2016 PROSE Award winner of the Best Textbook Award in Biological and Life Sciences - Provides a focused tutorial introduction to the core diseases of the nervous system - Includes comprehensive introductions to Stroke, Epilepsy, Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, ALS, Head and Spinal Cord Trauma, Multiple Sclerosis, Brain Tumors, Depression, Schizophrenia and many other diseases of the nervous system - Covers more than 40 diseases from the foundational science to the best treatment protocols - Includes discussions of translational research, drug discovery, personalized medicine, ethics, and neuroscience - New Edition features two new chapters on Pain and Addiction