Trail Fas Ligand Tnf And Tlr3 In Cancer

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TRAIL, Fas Ligand, TNF and TLR3 in Cancer

Author : Olivier Micheau
Publisher : Springer
ISBN 13 : 3319568051
Total Pages : 320 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis TRAIL, Fas Ligand, TNF and TLR3 in Cancer by : Olivier Micheau

Download or read book TRAIL, Fas Ligand, TNF and TLR3 in Cancer written by Olivier Micheau and published by Springer. This book was released on 2017-07-03 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the current understanding of death receptor's/TLR3 signaling regulation in cancer. Death receptors, including TRAIL-R1, TRAIL-R2, Fas and TNF-RI, owing to their ability to trigger apoptosis and to contribute to the elimination of cancer cells by the immune system have been considered, to variable extent, as important therapeutic targets for cancer therapy. But an increasing body of evidence suggests that some of these receptors may also contribute to tumorigenesis, or that new players such as TLR3 may be targeted for cancer therapy due to their ability to behave like death receptors.

TNFR Superfamily Oligomerization and Signaling

Author : Cristian Roberto Smulski
Publisher : Frontiers Media SA
ISBN 13 : 2889668460
Total Pages : 132 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis TNFR Superfamily Oligomerization and Signaling by : Cristian Roberto Smulski

Download or read book TNFR Superfamily Oligomerization and Signaling written by Cristian Roberto Smulski and published by Frontiers Media SA. This book was released on 2021-06-08 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cell Death Regulation in Health and Disease - Part A

Author :
Publisher : Academic Press
ISBN 13 : 0128201347
Total Pages : 254 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Cell Death Regulation in Health and Disease - Part A by :

Download or read book Cell Death Regulation in Health and Disease - Part A written by and published by Academic Press. This book was released on 2020-04-02 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Death Regulation in Health and Disease - Part A, Volume 351, the latest release in the International Review of Cell and Molecular Biology reviews current advances in cell and molecular biology. The series publishes timely topics authored by prominent cell and molecular biologists. This release is part of a 3-part series which comprises a comprehensive view of cell death regulation in a variety of biological contexts. Chapters cover Membrane dynamics in cell death regulation, The role of necroptosis in intestinal dysfunction, Regulation of cell death in the cardiovascular system, Cell death in bacterial and viral infection, and much more. - Provides a comprehensive collection of front-of-the line research in the field of cell death regulation - Authored by established and active cell and molecular biologists and drawn from international sources - Includes invited review articles that cover selected topics in multiple organisms and disease settings

Tumor Suppressor Par-4

Author : Vivek M. Rangnekar
Publisher : Springer Nature
ISBN 13 : 3030735729
Total Pages : 328 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Tumor Suppressor Par-4 by : Vivek M. Rangnekar

Download or read book Tumor Suppressor Par-4 written by Vivek M. Rangnekar and published by Springer Nature. This book was released on 2022-01-08 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Par-4 is a tumor suppressor protein first discovered and identified in 1993 by Dr. Vivek Rangnekar’s laboratory in prostate cancer cells undergoing apoptosis. Par-4 (later also known as PAWR) is a naturally occurring tumor suppressor. Studies have indicated that Par-4 selectively induces apoptosis in cancer cells while leaving normal, healthy, cells unaffected. Mechanisms contributing to the cancer-selective action of Par-4 have been associated with protein kinase A activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. Par-4 is downregulated, inactivated or mutated in diverse cancers. This first of two volumes will be the first on the market on the topic of Par-4, and will provide the opportunity for researchers to discuss the future direction of studies, broaden the scope of research, and contribute a more complete understanding of the molecule’s structural features, key functional domains, regulation and relevant basic and clinical/translational facets.

Engineered immune cells in cancer immunotherapy (EICCI)

Author : Cristina Maccalli
Publisher : Frontiers Media SA
ISBN 13 : 2832515606
Total Pages : 659 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Engineered immune cells in cancer immunotherapy (EICCI) by : Cristina Maccalli

Download or read book Engineered immune cells in cancer immunotherapy (EICCI) written by Cristina Maccalli and published by Frontiers Media SA. This book was released on 2023-02-28 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oncogene and Cancer

Author : Yahwardiah Siregar
Publisher : Inst za onkologiju i radiol
ISBN 13 : 9535108581
Total Pages : 497 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Oncogene and Cancer by : Yahwardiah Siregar

Download or read book Oncogene and Cancer written by Yahwardiah Siregar and published by Inst za onkologiju i radiol. This book was released on 2013-01-24 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. The book was divided into six main sections: 1. HER2 Carcinogenesis: Etiology, Treatment and Prevention; 2. DNA Repair Mechanism and Cancer; 3. New Approach to Cancer Mechanism; 4. New Role of Oncogenes and Tumor Suppressor Genes; 5. Non Coding RNA and Micro RNA in Tumorigenesis; 6. Oncogenes for Transcription Factors

Necrotic Cell Death

Author : Han-Ming Shen
Publisher : Springer Science & Business Media
ISBN 13 : 1461482208
Total Pages : 402 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Necrotic Cell Death by : Han-Ming Shen

Download or read book Necrotic Cell Death written by Han-Ming Shen and published by Springer Science & Business Media. This book was released on 2014-03-29 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.

Holland-Frei Cancer Medicine 8

Author : James F. Holland
Publisher : PMPH-USA
ISBN 13 : 9781607950141
Total Pages : 2052 pages
Book Rating : 4.9/5 (51 download)

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Book Synopsis Holland-Frei Cancer Medicine 8 by : James F. Holland

Download or read book Holland-Frei Cancer Medicine 8 written by James F. Holland and published by PMPH-USA. This book was released on 2010 with total page 2052 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland Frei Cancer Medicine serves as a quick reference to current information on an extensive list of cancers, including breast, lung, thyroid, colorectal, ovarian, prostate, and gastric cancer, to name but a few. Presented as an accessible pocket-sized handbook, the chapters are organized in an outline format, offering only the most essential information on the etiology, staging (including TNM staging) and treatment for each cancer type. Individual chapters are devoted to the molecular biology of cancer, cancer prevention, cancer screening, the mechanisms of chemotherapy, and diagnostic imaging in cancer. Additionally, each chapter lists all the major phase III clinical trials, and therefore, serves as an excellent reference of the major randomized controlled trials for each cancer reported to date. Specific chapters are also dedicated to the discussion of oncologic emergencies, pain and palliation, and prescription complications. At the conclusion of the book, a glossary of oncologic terms and chemotherapeutic drug programs, a table of common cancer incidences, and an overview of the mechanisms, common uses, and related toxicities of various anti-cancer agents are featured. In addition, performance status tables, mathematical formulas and a listing of common biomedical / cancer web sites are highlighted.

Oncoimmunology

Author : Laurence Zitvogel
Publisher : Springer
ISBN 13 : 3319624318
Total Pages : 700 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Oncoimmunology by : Laurence Zitvogel

Download or read book Oncoimmunology written by Laurence Zitvogel and published by Springer. This book was released on 2017-12-13 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.

Inflammation and Cancer

Author : Bharat B. Aggarwal
Publisher : Springer
ISBN 13 : 3034808372
Total Pages : 489 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Inflammation and Cancer by : Bharat B. Aggarwal

Download or read book Inflammation and Cancer written by Bharat B. Aggarwal and published by Springer. This book was released on 2014-05-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Engineered Targeted Cancer Immunotherapies

Author : Massimo Fantini
Publisher : Frontiers Media SA
ISBN 13 : 2889766691
Total Pages : 285 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Engineered Targeted Cancer Immunotherapies by : Massimo Fantini

Download or read book Engineered Targeted Cancer Immunotherapies written by Massimo Fantini and published by Frontiers Media SA. This book was released on 2022-08-01 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 2454 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Amphioxus Immunity

Author : An-Long Xu
Publisher : Elsevier
ISBN 13 : 0128096470
Total Pages : 306 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Amphioxus Immunity by : An-Long Xu

Download or read book Amphioxus Immunity written by An-Long Xu and published by Elsevier. This book was released on 2015-12-31 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amphioxus Immunity: Tracing the Origin of Human Immunity covers a remarkable range of information about Amphioxus and its evolutionary context. This compilation of what is currently known about Amphioxus, with a sharp focus on its immune system, includes 13 topics, such as: Amphioxus as a model for understanding the evolution of vertebrates basic knowledge of immunology immune organs and cells of amphioxus a genomic and transcriptomic view of the Amphioxus immunity pattern recognition system in Amphioxus transcription factors in Amphioxus the complement system of Amphioxus the oxidative burst system in Amphioxus immune effectors in Amphioxus lipid signaling of immune response in Amphioxus apoptosis in amphioxus; primitive adaptive immune system of Amphioxus and future research directions This valuable reference book is loaded with information that will be useful for anyone who wishes to learn more about the origin of vertebrates and adaptive immunity. Provides new evidence on the origin of the adaptive immune system, the evolution of innate immunity, and evolution-stage specific immune defense mechanisms Not only presents the cells and molecules involved in the adaptive immune response in Amphioxus, but also characterizes the origination and evolution of the gene families and pathways involved in innate immunity Includes much pioneering work, from the molecular, genomic, and cellular to the individual level

Identification, function and mechanisms of interferon induced genes associated with viruses

Author : Chang Li
Publisher : Frontiers Media SA
ISBN 13 : 2832514693
Total Pages : 157 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Identification, function and mechanisms of interferon induced genes associated with viruses by : Chang Li

Download or read book Identification, function and mechanisms of interferon induced genes associated with viruses written by Chang Li and published by Frontiers Media SA. This book was released on 2023-02-15 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tumor Microenvironment

Author : Alexander Birbrair
Publisher : Springer Nature
ISBN 13 : 3030492702
Total Pages : 226 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Tumor Microenvironment by : Alexander Birbrair

Download or read book Tumor Microenvironment written by Alexander Birbrair and published by Springer Nature. This book was released on 2020-10-29 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include eosinophils, NK cells, γδ T cells, regulatory T Cells, Langerhans cells, hematopoietic stem cells, Mast cells, B cells and Microglia, and more. Taken alongside its companion volumes, Tumor Microenvironment: Hematopoietic Cells – Part B updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Non-coding RNAs and Cancer

Author : Muller Fabbri
Publisher : Springer Science & Business Media
ISBN 13 : 1461484448
Total Pages : 287 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Non-coding RNAs and Cancer by : Muller Fabbri

Download or read book Non-coding RNAs and Cancer written by Muller Fabbri and published by Springer Science & Business Media. This book was released on 2013-10-28 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and unexpected functions for microRNAs are being revealed, leading to the identification of new anticancer molecular targets. This book represents a comprehensive guide on non-coding RNAs and cancer, spanning from its role as cancer biomarkers, to providing the most useful bioinformatic tools, to presenting some of the most relevant discoveries, which indicates how these fascinating molecules act as fine orchestrators of cancer biology.

Cancer Immunology

Author : Nima Rezaei
Publisher : Springer
ISBN 13 : 3662440067
Total Pages : 633 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Cancer Immunology by : Nima Rezaei

Download or read book Cancer Immunology written by Nima Rezaei and published by Springer. This book was released on 2014-12-02 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. This volume is focused on immunopathology of cancers. The interactions between cancerous cells and various components of the innate and adaptive immune system are fully described. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the most recent research and new developments in the field. Over the past decade, understanding of the interactions between the immune system and cancerous cells has increased markedly, leading to the development of combinatorial immunotherapeutic strategies to combat cancer. This translational, clinically oriented book will be of special value to clinical immunologists, hematologists and oncologists.