Toxicology of the Kidney

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Author :
Publisher : CRC Press
ISBN 13 : 9780881678857
Total Pages : 588 pages
Book Rating : 4.6/5 (788 download)

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Book Synopsis Toxicology of the Kidney by : Jerry B. Hook

Download or read book Toxicology of the Kidney written by Jerry B. Hook and published by CRC Press. This book was released on 1993-06-30 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides a synthesis of recent research on the mechanisms of chemically-induced kidney injury. The text includes a review of current concepts of clinical nephrotoxicity and renal failure, and mechanisms of specific classes of nephrotoxic drugs and environmental chemicals.

Toxicology of the Kidney, 3rd Edition

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Author :
Publisher : CRC Press
ISBN 13 : 9780415248648
Total Pages : 1176 pages
Book Rating : 4.2/5 (486 download)

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Book Synopsis Toxicology of the Kidney, 3rd Edition by : Joan B. Tarloff

Download or read book Toxicology of the Kidney, 3rd Edition written by Joan B. Tarloff and published by CRC Press. This book was released on 2005 with total page 1176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy, biochemistry, and physiology of the kidney. The text explains how these factors are related to concepts of clinical nephrotoxicity and renal failure in humans, and how animal models can be used to understand the mechanisms of human renal disease. In addition to updating many of the key elements of previous editions, such as in vitro models for studying renal function and toxicity and classic nephrotoxicants, it also incorporates cutting edge information on newly emerging areas of renal research. These include mechanisms of cell injury, signaling pathways, biomarkers of renal disease and the interface between basic renal science and clinical outcomes. This book includes current reviews of unpublished and recently published information which allows it to serve as a concise compendium of many key topics that will continue to play a central role in our understanding and treatment of nephrotoxicity for decades to come.

Toxicology of the Kidney

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Author :
Publisher : CRC Press
ISBN 13 : 0203646991
Total Pages : 991 pages
Book Rating : 4.2/5 (36 download)

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Book Synopsis Toxicology of the Kidney by : Ferdinand Rodriguez

Download or read book Toxicology of the Kidney written by Ferdinand Rodriguez and published by CRC Press. This book was released on 2004-12-28 with total page 991 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy

Toxicology of the Kidney

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Author :
Publisher : CRC Press
ISBN 13 : 1134536518
Total Pages : 1413 pages
Book Rating : 4.1/5 (345 download)

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Book Synopsis Toxicology of the Kidney by : Ferdinand Rodriguez

Download or read book Toxicology of the Kidney written by Ferdinand Rodriguez and published by CRC Press. This book was released on 2004-12-28 with total page 1413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy

Biologic Markers in Urinary Toxicology

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Author :
Publisher : National Academies Press
ISBN 13 : 0309052289
Total Pages : 322 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Biologic Markers in Urinary Toxicology by : National Research Council

Download or read book Biologic Markers in Urinary Toxicology written by National Research Council and published by National Academies Press. This book was released on 1995-08-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diseases of the kidney, bladder, and prostate exact an enormous human and economic toll on the population of the United States. This book examines prevention of these diseases through the development of reliable markers of susceptibility, exposure, and effect and the promise that new technologies in molecular biology and sophisticated understanding of metabolic pathways, along with classical approaches to the study of nephrotoxicants and carcinogens, can be developed and prevention of the diseases achieved. The specific recommendations included in this book complement those made in the previous three volumes on biomarkers, Biologic Markers in Reproductive Toxicology (1989), Biologic Markers in Pulmonary Toxicology (1989), and Biologic Markers in Immunotoxicology (1991).

Toxicology of the Kidney, Third Edition

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Author :
Publisher : CRC Press
ISBN 13 : 0415248647
Total Pages : 1200 pages
Book Rating : 4.4/5 (152 download)

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Book Synopsis Toxicology of the Kidney, Third Edition by : Joan B. Tarloff

Download or read book Toxicology of the Kidney, Third Edition written by Joan B. Tarloff and published by CRC Press. This book was released on 2004-12-28 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy, biochemistry, and physiology of the kidney. The text explains how these factors are related to concepts of clinical nephrotoxicity and renal failure in humans, and how animal models can be used to understand the mechanisms of human renal disease. In addition to updating many of the key elements of previous editions, such as in vitro models for studying renal function and toxicity and classic nephrotoxicants, it also incorporates cutting edge information on newly emerging areas of renal research. These include mechanisms of cell injury, signaling pathways, biomarkers of renal disease and the interface between basic renal science and clinical outcomes. This book includes current reviews of unpublished and recently published information which allows it to serve as a concise compendium of many key topics that will continue to play a central role in our understanding and treatment of nephrotoxicity for decades to come.

Kidney

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Author :
Publisher : CRC Press
ISBN 13 : 146658811X
Total Pages : 236 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Kidney by : Sang Geon Kim

Download or read book Kidney written by Sang Geon Kim and published by CRC Press. This book was released on 2013-09-11 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments, this book describes major areas of progress in the laboratory and clinic. In the first section, aspects of cellular organelles are discussed. The second section covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. In the third section, the recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally, the book discusses clinical implications of acute and chronic renal toxicity.

Casarett & Doull's Essentials of Toxicology

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Author :
Publisher :
ISBN 13 : 9781259255359
Total Pages : 524 pages
Book Rating : 4.2/5 (553 download)

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Book Synopsis Casarett & Doull's Essentials of Toxicology by : CURTIS. WATKINS KLAASSEN (JOHN.)

Download or read book Casarett & Doull's Essentials of Toxicology written by CURTIS. WATKINS KLAASSEN (JOHN.) and published by . This book was released on 2015-09-16 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pediatric Nephrology

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Publisher : Springer Science & Business Media
ISBN 13 : 3540763279
Total Pages : 2059 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Pediatric Nephrology by : Ellis D. Avner

Download or read book Pediatric Nephrology written by Ellis D. Avner and published by Springer Science & Business Media. This book was released on 2009-08-20 with total page 2059 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an extensive update of Pediatric Nephrology, which has become the standard reference text in the field. It is global in perspective and reflects the international group of editors, who are well-recognized experts in pediatric nephrology. Within this text, the development of kidney structure and function is followed by detailed and comprehensive chapters on all childhood kidney diseases.

Methods in Renal Toxicology

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Publisher : CRC Press
ISBN 13 : 9781439805602
Total Pages : 462 pages
Book Rating : 4.8/5 (56 download)

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Book Synopsis Methods in Renal Toxicology by : Rudolfs K. Zalups

Download or read book Methods in Renal Toxicology written by Rudolfs K. Zalups and published by CRC Press. This book was released on 1996-03-14 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only up-to-date compilation of renal methods available, this book is the definitive resource for any renal researcher eager to stay ahead. Methods in Renal Toxicology presents a vast array of methods for the study of renal cellular and tubular structure, function, and biochemistry under physiological, toxicological, and pathological conditions. It provides detailed descriptions in easy-to-understand language of methods designed to enhance your research efforts. Methods in Renal Toxicology puts you on the cutting edge with valuable chapters detailing molecular methods and transgene and gene targeting - the most recent approaches to the study of renal toxicology. Overall, the book's topics range from non-invasive assessments of renal function in the whole animal and clinical settings to cellular and molecular approaches. Specifically, the book delves into measurements of clearance and urinary markers, histopathology, and methods to assess renal carcinogenesis, mutagenesis, oxidative stress, mitochondria injury, cellular repair, and drug metabolism and transport. A variety of in vitro methods are also described, including the isolated perfused kidney, micropuncture, microperfusion, microdissection, renal slices, isolated perfused tubules, suspensions of tubules and isolated cells, and primary cell cultures and cell lines. Methods in Renal Toxicology is a must-have resource for all renal investigators. Nowhere else can you find concise descriptions of traditional and up-to-the-minute renal toxicology methods in such a practical, well-written single-volume guide.

Uremic Toxins

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Publisher : Springer Science & Business Media
ISBN 13 : 1468454455
Total Pages : 292 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Uremic Toxins by : Severin Ringoir

Download or read book Uremic Toxins written by Severin Ringoir and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book contains the Proceedings of a two day Symposium on Uremic Toxins organized at the University of Ghent in Belgium. A series of guest lectures, free communications and posters have been presented. An international audience of 163 scientists from 16 nationalities listened to and discussed extensively a spectrum of topics brought forward by colleagues and researchers who worked for many years in the field of Uremic Toxins. There is a striking contrast between all the new dialysis strategies available in the work to "clean" the uremic patients and the almost non-progression of our knowledge on uremic toxins in the past decade. In this sense the symposium was felt by all participants as a new start for the research in the biochemical field of the definition of uremia. If the present volume would stimulate new work in this field in order to define uremia, or identify the uremic toxins, the purpose of the organizers would be maximally fulfilled.

Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances

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Author :
Publisher : IARC Monographs on the Evaluat
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 1999 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allyl isothiocyanate; ortho-Anisidine; Atrazine; Butyl benzyl phthalate; Chloroform; Chlorothalonil;Cyclamates;Dichlorobenzenes;Hexachlorobutadiene; Hexachloroethane; d-Limonene; Melamine; Methyl tert-butyl ether; Nitrilotriaceticacid andits salts;Paracetamol; ortho-Phenylphenol and its sodium salt; Potassium bromate ;Quercetin; Saccharin and its salts;Simazine

Tropical Nephrology

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Author :
Publisher : Springer Nature
ISBN 13 : 3030445003
Total Pages : 320 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Tropical Nephrology by : Geraldo Bezerra da Silva Junior

Download or read book Tropical Nephrology written by Geraldo Bezerra da Silva Junior and published by Springer Nature. This book was released on 2020-06-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides an introduction to the fascinating field of tropical nephrology, covering nephrology, infectious diseases and tropical medicine. These topics are connected since numerous infectious and parasitic diseases affect the kidneys and are endemic in the tropical areas of the globe. Considered neglected tropical diseases by the World Health Organization, they are largely linked to poverty and lack policies to prevent, treat and decrease their prevalence and incidence. The tropics currently encompass nearly 150 countries and account for 40% of the world's population, and it is predicted that by 2050 this figure will rise to 55%. Most of the countries in the tropical regions have been classified by the World Bank as low-middle income countries and have limited access to services, including health care. As such, this highly topical book is of interest to a large number of healthcare professionals and researchers who are in contact with tropical diseases, especially those investigating their complications, such as kidney injury. Divided into 23 chapters, it describes the most prevalent tropical diseases and conditions that affect the kidneys. It also presents the most recent epidemiological data, clinical manifestations, details of kidney involvement, including the pathophysiology of kidney injury, and the current treatment for each disease.

An Introduction to Toxicology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 144715553X
Total Pages : 338 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis An Introduction to Toxicology by : Philip C. Burcham

Download or read book An Introduction to Toxicology written by Philip C. Burcham and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​

Principles of Toxicology

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Publisher : John Wiley & Sons
ISBN 13 : 0471459232
Total Pages : 625 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Principles of Toxicology by : Phillip L. Williams

Download or read book Principles of Toxicology written by Phillip L. Williams and published by John Wiley & Sons. This book was released on 2003-10-10 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and expanded edition of the bestselling guide on toxicology and its practical application The field of toxicology has grown enormously since Industrial Toxicology: Safety and Health Applications in the Workplace was first published in 1985. And while the original edition was hugely popular among occupational health professionals, the time is ripe to address toxic agents not only in the industrial setting but also in the environment at large. Renamed Principles of Toxicology: Environmental and Industrial Applications, this new edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields, Principles of Toxicology, Second Edition features: Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems Coverage of occupational medicine and epidemiological issues The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins Special emphasis on the evaluation and control of toxic hazards Specific case histories on applying risk assessment methods in the modern workplace Ample figures, references, and a comprehensive glossary of toxicological terms

Alternatives to Animal Testing

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Author :
Publisher : Springer
ISBN 13 : 9811324476
Total Pages : 130 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Alternatives to Animal Testing by : Hajime Kojima

Download or read book Alternatives to Animal Testing written by Hajime Kojima and published by Springer. This book was released on 2018-12-27 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.

Renal Pharmacotherapy

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Publisher : Springer Nature
ISBN 13 : 3030586502
Total Pages : 830 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Renal Pharmacotherapy by : Larry K. Golightly

Download or read book Renal Pharmacotherapy written by Larry K. Golightly and published by Springer Nature. This book was released on 2021-09-24 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt: To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function. Failure to enjoin appropriate dosage adjustments in patients with abnormal or rapidly changing kidney function continues to lead to reports of drug toxicity involving a broad array of renally eliminated medications. This updated edition captures nearly 200 new drugs that have been approved by the FDA since the initial publication of Renal Pharmacotherapy. It also covers new evidence that has emerged regarding the need to adjust dosage of certain older medications that are eliminated by the kidneys. Additionally, it presents new data that are being continuously derived in the areas of patient-specific dose individualization for drugs of all types. Comprehensive, convenient, and evidence-based, this reference closes several identified knowledge gaps and will continue to be the leading collection of dosage recommendations for patients with compromised kidney function.