Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances

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Author :
Publisher : Humana Press
ISBN 13 : 3319155180
Total Pages : 500 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances by : Jamie C. DeWitt

Download or read book Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances written by Jamie C. DeWitt and published by Humana Press. This book was released on 2015-04-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.

Mammalian Toxicology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119940419
Total Pages : 716 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Mammalian Toxicology by : Mohamed Abou-Donia

Download or read book Mammalian Toxicology written by Mohamed Abou-Donia and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian Toxicology surveys chemical agents and examines how such chemicals impact on human health, emphasizing the importance in minimizing environmental exposure to chemical and physical hazards in our homes, communities and workplaces through such media as contaminated water, soil and air. Starting with the basic principles on a wide range of toxic agents, this textbook describes how they enter the body, their mechanisms of action once inside, and strategies for diagnosis, prevention and treatment. Topics covered include: General principles of toxicology: pharmacological and toxicological principles underpinning the study of toxicology, risk assessments and mechanisms of cell death Disposition: routes of chemical exposures, entry into the body and various tissues, storage, metabolic biotransformation and elimination, with examples from various toxicants. Toxic agents: the occurrences, disposition in the body, health effects, toxic mechanisms, antidotes and treatments of a range of agents including pesticides, metals, solvents, gases, nanomaterials, food components and additives, pharmaceuticals, drugs of abuse, natural toxins, endocrine disruptors, radiation, and warfare weapons. Toxic effects: including neurotoxicity, developmental toxicity, immunotoxicity, teratogenecity, male and female reproductive toxicity, mutagenecity, carcinogenicity, pulmonary toxicity, cardiovascular toxicity, hepatotoxicity, gastrointestinal toxicity and cardiovascular toxicity Toxicology and society: epidemiological studies of chemical-induced diseases in human populations, and a vision for toxicology in the 21st century. Mammalian Toxicology is an essential primer for students of toxicology, biochemistry, biology, medicine and chemistry. It is also appropriate for professional toxicologists in research or regulatory affairs, and anyone who needs to understand the adverse effects of toxic agents on the human body.

Perfluoroalkyl Substances in the Environment

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Author :
Publisher : CRC Press
ISBN 13 : 0429945035
Total Pages : 498 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Perfluoroalkyl Substances in the Environment by : David M. Kempisty

Download or read book Perfluoroalkyl Substances in the Environment written by David M. Kempisty and published by CRC Press. This book was released on 2018-08-06 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Per- and polyfluorinated alkyl substances (PFAS), often referred to as per- (and poly) fluorinated compounds (PFCs), have been used for years in many everyday3⁄4 and some lifesaving3⁄4 products. However, their use has been linked to adverse health effects in humans, a problem compounded by their persistence in the environment. This book discusses the various challenges of PFAS in our environment today, including their historical use as well as their chemical and toxicological properties. It also presents robust discussion of analytical challenges and special considerations in sampling. The work goes on to give practical recommendations for dealing with these compounds in today's dynamic regulatory landscape and includes several chapters on various remediation techniques. Key Features: Comprehensive overview of per- and polyfluorinated alkyl substances (PFAS) historical use and chemical/physical properties which help us understand their persistence, transport, and transformation pathways in the environment In-depth analysis of PFAS toxicology Detailed descriptions of conventional and state-of-the-art remediation technologies Practical recommendations for dealing with PFAS in a dynamic regulatory landscape Robust discussion of important sampling and analytical considerations Perfluoroalkyl Substances in the Environment: Theory, Practice, and Innovation explores the challenges across the topical areas of regulation and management, toxicology, environmental remediation, and analytical sampling and analysis.Readers will find this text helpful in understanding complexities associated with PFAS and informing management strategies to effectively protect this and future generations.

Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS)

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Author :
Publisher : CRC Press
ISBN 13 : 1000375862
Total Pages : 177 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) by : Mark S. Johnson

Download or read book Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) written by Mark S. Johnson and published by CRC Press. This book was released on 2021-04-21 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) provides the most recent summary of toxicity data relevant to mammals, birds, reptiles, and amphibians, and provides values for use in risk assessment applications. Predicting the bioaccumulation of PFAS in terrestrial wildlife (including humans) has proven to be extremely complex. As a group, PFAS act differently than traditional non-ionic organic molecules, where PFAS can break down and reform, whereas some are demonstrated to be extremely persistent. Where sufficient data are provided, this book establishes toxicity reference values (TRVs), which are derived to assist in characterizing environmental sources of contamination and making risk-based decisions. Features: Provides toxicity reference values (TRVs) for vertebrates (mammals, birds, amphibians) for PFAS, where sufficient data are available, and includes objective supporting background information. Assigns a level of confidence to each TRV to provide the risk assessor with an understanding of the relative uncertainty associated with each value. Presents toxicity data in the formats of scatter diagrams and tables for quick review and assessment. Provides TRVs relevant for screening and decision making This book serves as a useful aid for risk assessors and managers in those industries that have sites contaminated with PFAS, consultants tasked with evaluating risks at such sites, and staff at regulatory agencies at various governmental levels, who need to know how much contamination is considered safe for wildlife. It will also appeal to researchers with an interest in filling the gaps in the current toxicological data for PFAS exposure.

Toxicity Studies of PER- and Polyfluoroalkyl Substances (PFAS)

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Author :
Publisher :
ISBN 13 :
Total Pages : 27 pages
Book Rating : 4.:/5 (126 download)

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Book Synopsis Toxicity Studies of PER- and Polyfluoroalkyl Substances (PFAS) by : Adenike Rofiyat Shittu

Download or read book Toxicity Studies of PER- and Polyfluoroalkyl Substances (PFAS) written by Adenike Rofiyat Shittu and published by . This book was released on 2021 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: Per- and polyfluoroalkyl substances (PFAS) are long carbon chain chemicals in which hydrogen atoms in aliphatic compounds are substituted by fluorine atoms. PFAS are known to be resistant to environmental and biological degradation and concerns are rising based on the emergence of the data that indicates a link between human exposure and certain diseases. This study explores the toxicological effects of polyfluorooctanoic acid (PFOA), polyfluorooctane sulphonoic acid (PFOS) and hexafluoropropylene oxide dimeric acid (GenX) on bacteria in order to identify cellular and molecular targets.Based on the preliminary knowledge of the wide-spread presence, non-biodegradability and the cycle of PFAS in the environment, this study quantifies the sensitivities of PFAS to different bacteria species. Rhodobacter sphaeroides was used as an environmental-based model for this study and Collinsella aerofaciens was used as a human microbiome-based model. The IC50 concentrations for PFOA, PFOS, and GenX were determined for R. sphaeroides grown under a variety of conditions. This information will leverage further studies aimed at identifying genes and gene products involved in PFAS toxicity in that organismFor the first time, PFAS sensitivity of a bacterium associated with the human gut microbiome was demonstrated. Since E. coli has been found to be insensitive to PFAS, this establishes that human ingestion of these chemicals has the potential to alter the composition of the gut microbiome. Spontaneously arising mutants with altered PFAS susceptibilities were subsequently isolated. Genomic DNA was successfully isolated from the wild type and mutant C. aerofaciens strains for sequencing. Using the sequence data, a list of candidate genes whose products are possible targets of PFAS toxicity in C. aerofaciens can be assembled.0́3

Perfluorinated Chemicals (PFCs)

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119363837
Total Pages : 271 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Perfluorinated Chemicals (PFCs) by : Nicholas P. Cheremisinoff

Download or read book Perfluorinated Chemicals (PFCs) written by Nicholas P. Cheremisinoff and published by John Wiley & Sons. This book was released on 2016-11-29 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume provides a timely study on the environmental challenges from a specific class of perfluorinated chemical compounds (PFCs) that are now being recognized as a worldwide health threat. Recent studies report that levels of classes of PFCs known as polyfluoroalkyl and perfluoroalkyl (PFASs) exceed federally recommended safety levels in public drinking-water supplies for 6 million people in the United States and that as many as 100 million people could be at risk from exposure to these chemicals. These chemicals occur globally in wildlife and humans. Both PFCAs and PFSAs have been produced for more than 50 years, but have only become of interest to regulators and environmentalists since the late 1990s. Recent advances in analytical methodology has enabled widespread detection in the environment and humans at trace levels. These toxic chemicals have been found in outdoor and indoor air, surface and drinking water, house dust, animal tissue, human blood serum, and human breast milk. Of great concern to communities is the presence of these compounds in a number of drinking water supplies in the U.S. and other countries. This new volume provides a timely explanation of the chemicals, provides a detailed review of the regulations both in the US and European Community, explains the health risk literature, and then explores in great detail available treatment technologies. The volume is a must for public water supply facilities, industrial operations that have historically used these chemicals and face legacy pollution issues, policy makers and the general public.

The cost of inaction

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Author :
Publisher : Nordic Council of Ministers
ISBN 13 : 9289360658
Total Pages : 194 pages
Book Rating : 4.2/5 (893 download)

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Book Synopsis The cost of inaction by : Gretta Goldenman

Download or read book The cost of inaction written by Gretta Goldenman and published by Nordic Council of Ministers. This book was released on 2019-03-17 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: PFAS (per and polyfluoroalkylsubstances) are known to be extremely difficult to degrade in the environment and to be bioaccumulative and toxic. Exposure to PFAS is suspected to increase the risk of adverse health effects, such as impacts on the thyroid gland, the liver, fat metabolism and the immune system. This study estimates the socioeconomic costs that may result from impacts on human health and the environment from the use of PFAS. Better awareness of the costs and problems associated with PFAS exposure will assist decision-makers and the general public to make more efficient and timely risk management decisions. Findings indicate that the costs are substantial, with annual health-related costs estimated to 2.8 – 4.6 billion EUR for the Nordic countries and 52 – 84 billion EUR for all EEA countries. Overall non-health costs are estimated at 46 million – 11 billion EUR for the Nordic countries.Upon request the excel spreadsheets used for the monetarisation and valuation in this report can also be provided along with a guidance on how to use the estimation of costs for value transfer. Please contact any of the consultants or members of the steering group from the Swedish Chemicals Agency or the Danish Environmental Protection Agency if you are interested in receiving these excel spreadsheets.

Organofluorine Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 1489912029
Total Pages : 651 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Organofluorine Chemistry by : R.E. Banks

Download or read book Organofluorine Chemistry written by R.E. Banks and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past fifteen years commercial interest in compounds containing carbon fluorine bonds has burgeoned beyond all expectations, mainly owing to business opportunities arising from work on biologically active fluoroorganics-particularly agrochemicals, the relentless search for new markets for fluoropolymers and fluoro carbon fluids, developments in the field of medical diagnostics, and the drive to find replacements for ozone-depleting CFCs and Halon fire-extinguishing agents. Judging the situation to warrant the publication of a comprehensive collection of up-to-date reviews dealing with commercial organofluorine compounds within a single volume of manageable size (and hence reasonable cost), we were delighted to be invited by Plenum Publishing Corporation to produce a suitable book. In order to provide an authentic and wide-ranging account of current commercial applications of fluoroorganic materials, it clearly was necessary to assemble a sizeable team of knowledgeable contributing authors selected almost entirely from industry. Through their efforts we have been able to produce an almost complete coverage of the modem organofluorochemicals business in a manner designed to attract a reader ship ranging from experts in the field, through chemists and technologists currently unaware of the extent of industrial involvement with fluoroorganics, to students of applied chemistry. Promised chapters dedicated to perfluoroolefin oxides and 18F labeling of radiopharmaceuticals failed to materialize. This is somewhat unfortunate in view of our aim to achieve comprehensive coverage of the subject.

Biotransformation, trace analysis and effects of perfluoroalkyl and polyfluoroalkyl substances

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Author :
Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.:/5 (918 download)

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Book Synopsis Biotransformation, trace analysis and effects of perfluoroalkyl and polyfluoroalkyl substances by :

Download or read book Biotransformation, trace analysis and effects of perfluoroalkyl and polyfluoroalkyl substances written by and published by . This book was released on 2012 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicity Assessment

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Publisher :
ISBN 13 : 9781071610916
Total Pages : 266 pages
Book Rating : 4.6/5 (19 download)

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Book Synopsis Toxicity Assessment by : Carlos M. Palmeira

Download or read book Toxicity Assessment written by Carlos M. Palmeira and published by . This book was released on 2021 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects protocols from different areas of knowledge to assist in the identification of toxic effects exerted by different xenobiotics. At the same time as classical techniques are presented, modern techniques with alternative models to the use of animals are also presented. Given the ever-increasing exposure to different compounds and their effects on population health, the assessment of multiple endpoints is of utmost importance for better risk assessment, and this collection addresses that need. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Toxicity Assessment: Methods and Protocols aims to serve researchers in this vast field of science as they seek to better understand the mechanisms of action of different xenobiotics.

Polyfluorinated Chemicals and Transformation Products

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Publisher : Springer Science & Business Media
ISBN 13 : 3642218717
Total Pages : 183 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Polyfluorinated Chemicals and Transformation Products by : Thomas P. Knepper

Download or read book Polyfluorinated Chemicals and Transformation Products written by Thomas P. Knepper and published by Springer Science & Business Media. This book was released on 2011-09-21 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to their unparalleled effectiveness and efficiency, polyfluorinated chemicals (PFC) have become essential in numerous technical applications. However, many PFCs brought to market show limited biodegradability, and their environmental persistence combined with toxic and bioaccumulative potential have become a matter of concern in some instances. This volume highlights the synthesis of PFCs, focusing on substances with improved application and environmental properties, which are a challenge for synthetic chemists. Further, modern mass spectrometric techniques for the detection and identification of biotransformation products of PFCs are described. The sorption and leaching behavior of PFC in soil is also addressed in order to predict their fate in the environment. Several contributions discuss the monitoring of PFCs in European surface, ground and drinking waters, treatment options for PFC removal from drinking water, occurrence in food, and the human biomonitoring of PFCs.

Chemometrics and Cheminformatics in Aquatic Toxicology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119681596
Total Pages : 596 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Chemometrics and Cheminformatics in Aquatic Toxicology by : Kunal Roy

Download or read book Chemometrics and Cheminformatics in Aquatic Toxicology written by Kunal Roy and published by John Wiley & Sons. This book was released on 2022-01-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: CHEMOMETRICS AND CHEMINFORMATICS IN AQUATIC TOXICOLOGY Explore chemometric and cheminformatic techniques and tools in aquatic toxicology Chemometrics and Cheminformatics in Aquatic Toxicology delivers an exploration of the existing and emerging problems of contamination of the aquatic environment through various metal and organic pollutants, including industrial chemicals, pharmaceuticals, cosmetics, biocides, nanomaterials, pesticides, surfactants, dyes, and more. The book discusses different chemometric and cheminformatic tools for non-experts and their application to the analysis and modeling of toxicity data of chemicals to various aquatic organisms. You’ll learn about a variety of aquatic toxicity databases and chemometric software tools and webservers as well as practical examples of model development, including illustrations. You’ll also find case studies and literature reports to round out your understanding of the subject. Finally, you’ll learn about tools and protocols including machine learning, data mining, and QSAR and ligand-based chemical design methods. Readers will also benefit from the inclusion of: A thorough introduction to chemometric and cheminformatic tools and techniques, including machine learning and data mining An exploration of aquatic toxicity databases, chemometric software tools, and webservers Practical examples and case studies to highlight and illustrate the concepts contained within the book A concise treatment of chemometric and cheminformatic tools and their application to the analysis and modeling of toxicity data Perfect for researchers and students in chemistry and the environmental and pharmaceutical sciences, Chemometrics and Cheminformatics in Aquatic Toxicology will also earn a place in the libraries of professionals in the chemical industry and regulators whose work involves chemometrics.

Toxic Effects and Exposure of Per- and Polyfluoroalkyl Substances in Cell-based Bioassays

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (143 download)

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Book Synopsis Toxic Effects and Exposure of Per- and Polyfluoroalkyl Substances in Cell-based Bioassays by : Weiping Qin

Download or read book Toxic Effects and Exposure of Per- and Polyfluoroalkyl Substances in Cell-based Bioassays written by Weiping Qin and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mixed Methods Research

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Publisher : Oxford University Press
ISBN 13 : 0190297638
Total Pages : 216 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Mixed Methods Research by : Daphne Watkins

Download or read book Mixed Methods Research written by Daphne Watkins and published by Oxford University Press. This book was released on 2015-08-03 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finally, a practical guide to mixed methods research has been written with health and human services professionals in mind. Watkins and Gioia review the fundamentals of mixed methods research designs and the general suppositions of mixed methods procedures, look critically at mixed method studies and models that have already been employed in social work, and reflect on the contributions of this work to the field. But what is most important is that they lead the reader through considerations for the application of the mixed methods research in social work settings. The chapters of this book are structured so that readers can (figuratively) walk through the mixed methods research process using nine steps. Chapters one, five, and six provide supplemental material meant to serve as grounding for chapters two, three, and four, which outline nine steps in the mixed methods research process, and specific to social work research. This is a short and practical guide not just for learning about mixed methods research, but also doing it.

Fluorinated Surfactants and Repellents, Second Edition,

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Author :
Publisher : CRC Press
ISBN 13 : 9780824704728
Total Pages : 650 pages
Book Rating : 4.7/5 (47 download)

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Book Synopsis Fluorinated Surfactants and Repellents, Second Edition, by : Erik Kissa

Download or read book Fluorinated Surfactants and Repellents, Second Edition, written by Erik Kissa and published by CRC Press. This book was released on 2001-02-09 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: A discussion of the synthesis, problems, theories and applications of fluorinated surfactants, this second edition is updated with four new chapters on repellency and protection against soiling and staining and over 2900 references, equations, and drawings (800 more than the previous edition). It lists alphabetically and explores numerous applications of fluorinated surfactants. Called "...a most useful introduction to these fascinating materials" by the Journal of Dispersion Science and Technology and "...a coherent and stimulating handbook...the most useful book in the fluorinated surfactants field to date. Recommended." by the Journal of the Chemical Society, Faraday Transactions - this book is a source of factual data, methods of manufacture, and chemical structures for the surfactant scientist and user.

Handbook of Catchment Management

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Publisher : John Wiley & Sons
ISBN 13 : 1119531225
Total Pages : 660 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Handbook of Catchment Management by : Robert C. Ferrier

Download or read book Handbook of Catchment Management written by Robert C. Ferrier and published by John Wiley & Sons. This book was released on 2021-07-13 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: HANDBOOK OF CATCHMENT MANAGEMENT In 2010, the first edition of the Handbook of Catchment Management provided a benchmark on how our understanding and actions in water management within a catchment context had evolved in recent decades. Over ten years on, the catchment management concept is entering a new phase of development aligned to contemporary and future challenges. These include climate change uncertainty, further understanding in ecological functioning under change, the drive for a low-carbon, energy efficient and circular society, multiple uses of water, the emergence of new pollutants of concern, new approaches to valuation, finance and pricing mechanisms, stewardship and community engagement, the integration of water across the Sustainable Development Goals (SDG) and the link between water, energy and food. These developments are framed within an increasingly data rich world where new analytics, sensor technology and processing power are informing increasingly real-time decision making. The challenge is also to increase cross-compliance and policy integration to meet multiple stakeholder objectives, and to link actions to achieve cost-effective outcomes. In addition, there are a number of new and exciting city, region and basin-scale real-world examples of contemporary and new catchment thinking; integrating science, technology, knowledge and governance to address multiple drivers and complex problems from across the globe. The time is now right, to capture the new challenges facing catchment management and water resources management globally. This revised and updated edition of the Handbook of Catchment Management features: Thoroughly rewritten chapters which provide an up-to-date view of catchment management issues and contexts New case study material highlighting multi-sectoral management in different globally significant basins and different geographical locations Up-to-date topics selected for their resonance not only in natural sciences and engineering, but also in other fields, such as socio-economics, law and policy The Handbook is designed for a broad audience, but will be particularly useful for advanced students, researchers, academics and water sector professionals such as planners, consultants and regulators.

PFASs in the Nordic environment

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Author :
Publisher : Nordic Council of Ministers
ISBN 13 : 9289360623
Total Pages : 156 pages
Book Rating : 4.2/5 (893 download)

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Book Synopsis PFASs in the Nordic environment by : Anna Kärrman

Download or read book PFASs in the Nordic environment written by Anna Kärrman and published by Nordic Council of Ministers. This book was released on 2019-03-15 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report describes a screening study of in all ninety-nine conventional and emerging per- and polyfluoroalkyl substances (PFASs) in the Nordic environment. In addition, extractable organic fluorine (EOF) was analysed. The latter can provide the amount, but not identity, of organofluorine in the samples, which in turn can be used to assess the mass balance between known and unknown PFASs. The study was initiated by the Nordic Screening Group and funded by these and the Nordic Council of Ministers through the Chemicals Group.A total of 102 samples were analyzed in this study, including bird eggs, fish, marine mammals, terrestrial mammals, surface water, WWTP effluents and sludge, and air. Samples were collected by institutes from the participating countries and self-governing areas; Denmark, Faroe Islands, Finland, Greenland, Iceland, Norway, and Sweden.