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Author : Annika Kers
Publisher :
ISBN 13 : 9789171539335
Total Pages : 51 pages
Book Rating : 4.5/5 (393 download)
Download or read book Towards Synthesis of Biologically Important Phosphate Analogues written by Annika Kers and published by . This book was released on 1999 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David C. Billington
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Inositol Phosphates Significance written by David C. Billington and published by Wiley-VCH. This book was released on 1993 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The transmission of messages across cell membranes is an essential process in complex organisms. The discovery of a new transmembrane signalling system, involving the production of inositol phosphates inside stimulated cells, has led to widespread interest in the chemical synthesis of the inositol phosphates and their analogues. This book provides a concise but comprehensive account of the methods of organic synthesis of inositol phosphates and supplements this with a general background treatment of the stereochemistry and nomenclature of the inositols. The biochemical importance and complexity of the system are also covered, as is the synthesis of inositol phosphate analogues. The book is intended for advanced undergraduate students, postgraduates and research workers in both university and industrial laboratories. '... an invaluable and well-written text for all those working on cellular secondary messengers ... the most comprehensive of all the reviews so far written in this very topical area.' Professor Steven V. Ley, Department of Chemistry, Cambridge University
Author : K. S. Bruzik
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 622 pages
Book Rating : 4.3/5 (91 download)
Download or read book Biophosphates and Their Analogues written by K. S. Bruzik and published by Elsevier Publishing Company. This book was released on 1987 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Annika Kers
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (852 download)
Download or read book Towards Symthesis of Biologically Important Phosphate Analogues written by Annika Kers and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gaia Ashlee Aish
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (13 download)
Download or read book The Synthesis and Enzymatic Evaluation of Biologically Relevant Sugar 1-Phosphonates written by Gaia Ashlee Aish and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780444426338
Total Pages : pages
Book Rating : 4.4/5 (263 download)
Download or read book Biophosphates and their analogues written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Serge L. Beaucage
Publisher : Current Protocols
ISBN 13 : 9780471246626
Total Pages : pages
Book Rating : 4.2/5 (466 download)
Download or read book Current Protocols in Nucleic Acid Chemistry written by Serge L. Beaucage and published by Current Protocols. This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Good methods must be reliable, well-tested, and honed to minimize the time and expense required to achieve the desired results. CPNC provides a continuously growing and evolving set of protocols that allows researchers to benefit from the experience of other researchers around the world. The core manual provides a comprehensive set of protocols that have been compiled, revised, and streamlined over the last 6 years. Quarterly updates provide new protocols in emerging areas of research as well as continued advances and new applications for fundamental methods. The book is designed to grow and change with the field of nucleic acid chemistry. Fundamental nucleoside chemistry methods include sugar-base condensation, phosphorylation, and nucleoside protection. Methods for oligonucleotide synthesis include H-phosphonate and phosphoramidite approaches, solid-phase and solution-phase synthesis, large-scale synthesis, synthesis for modified and unmodified oligonucleotides, conjugation of oligonucleotides, synthesis without base protection, and synthesis on microarrays. More specialized synthetic methods include synthesis of biologically active nucleosides and prodrugs. Purification and characterization methods are detailed. Advanced methods include biophysical analysis, combinatorial methods, and nanotechnology. Each protocol includes rationale for choosing appropriate methods, step-by-step procedures, complete recipes, anticipated results, characterization data, and troubleshooting, as well as background and recommended reading. The level of procedural detail is far beyond that found in the research literature, and tips and comments from authors are geared towards ensuring reliable duplication in the laboratory.
Author : David Churchill
Publisher : BoD – Books on Demand
ISBN 13 : 1789850398
Total Pages : 216 pages
Book Rating : 4.7/5 (898 download)
Download or read book Contemporary Topics about Phosphorus in Biology and Materials written by David Churchill and published by BoD – Books on Demand. This book was released on 2020-09-09 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a diverse set of topics regarding phosphorus chemistry, namely phosphates and closely related chemical systems. Divided into two sections, chapters cover such topics as phosphate dynamics and phosphates in biomaterials. This volume is a useful reference for scholars and researchers and will inspire readers to make future discoveries in the field.
Author : Jesús Fernández Lucas
Publisher : John Wiley & Sons
ISBN 13 : 3527343768
Total Pages : 348 pages
Book Rating : 4.5/5 (273 download)
Download or read book Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives written by Jesús Fernández Lucas and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of innovative tools for creative nucleic acid chemists that open the door to novel probes and therapeutic agents Nucleic acids continue to gain importance as novel diagnostic and therapeutic agents. With contributions from noted scientists and scholars, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practical reference that includes a wide range of approaches for the synthesis of designer nucleic acids and their derivatives. The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications. This important book: -Presents a timely and topical guide to the synthesis of designer nucleic acids and their derivatives -Addresses the growing market for nucleotide-derived pharmaceuticals used as anti-infectives and chemotherapeutic agents, as well as fungicides and other agrochemicals. -Covers novel methods and the most recent trends in the field -Contains contributions from an international panel of noted scientistics Written for biochemists, medicinal chemists, natural products chemists, organic chemists, and biotechnologists, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practice-oriented guide that reviews innovative methods for the enzymatic as well as non-enzymatic synthesis of nucleic acid species.
Author : Jean-Luc Montchamp
Publisher : Springer
ISBN 13 : 3319154737
Total Pages : 250 pages
Book Rating : 4.3/5 (191 download)
Download or read book Phosphorus Chemistry I written by Jean-Luc Montchamp and published by Springer. This book was released on 2015-03-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Author : Robert J. Ouellette
Publisher : Academic Press
ISBN 13 : 0128026340
Total Pages : 498 pages
Book Rating : 4.1/5 (28 download)
Download or read book Principles of Organic Chemistry written by Robert J. Ouellette and published by Academic Press. This book was released on 2015-02-13 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Class-tested and thoughtfully designed for student engagement, Principles of Organic Chemistry provides the tools and foundations needed by students in a short course or one-semester class on the subject. This book does not dilute the material or rely on rote memorization. Rather, it focuses on the underlying principles in order to make accessible the science that underpins so much of our day-to-day lives, as well as present further study and practice in medical and scientific fields. This book provides context and structure for learning the fundamental principles of organic chemistry, enabling the reader to proceed from simple to complex examples in a systematic and logical way. Utilizing clear and consistently colored figures, Principles of Organic Chemistry begins by exploring the step-by-step processes (or mechanisms) by which reactions occur to create molecular structures. It then describes some of the many ways these reactions make new compounds, examined by functional groups and corresponding common reaction mechanisms. Throughout, this book includes biochemical and pharmaceutical examples with varying degrees of difficulty, with worked answers and without, as well as advanced topics in later chapters for optional coverage. Incorporates valuable and engaging applications of the content to biological and industrial uses Includes a wealth of useful figures and problems to support reader comprehension and study Provides a high quality chapter on stereochemistry as well as advanced topics such as synthetic polymers and spectroscopy for class customization
Author : John Goodchild
Publisher : Humana Press
ISBN 13 : 9781617791895
Total Pages : 340 pages
Book Rating : 4.7/5 (918 download)
Download or read book Therapeutic Oligonucleotides written by John Goodchild and published by Humana Press. This book was released on 2011-07-18 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of oligonucleotide therapeutics research is ripe with the prospect of new discoveries. In Therapeutic Oligonucleotides: Methods and Protocols, a selection of established and emerging methods for the application of oligonucleotides as therapeutics are presented, all providing the tools needed to inspire great changes in the field. Divided into twenty-one chapters, this detailed volume meticulously describes vital protocols for optimizing and improving cell uptake, such as photochemical internalization, modified cell penetrating peptides, antibody conjugates, and nanoparticles. Other chapters address quantitation of RNA therapeutics in cells, assaying gene knockdown, selecting the best target site and synthesis of various modified oligonucleotides. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Therapeutic Oligonucleotides: Methods and Protocols serves as a timely resource for both professionals and novices pursuing research in this exciting and pioneering field.
Author : Shaul Massry
Publisher : Springer Science & Business Media
ISBN 13 : 1461342171
Total Pages : 611 pages
Book Rating : 4.4/5 (613 download)
Download or read book Phosphate Metabolism written by Shaul Massry and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: We present to our readers the proceedings of the Second International Workshop on Phosphate. A short account of the history of the effort led to the Phosphate Workshops is appro priate and can be of interest to the reader. The idea for Phosphate Workshops was born in the early days of November, 1974. One of us (S. G. M. ) suggested the thought to a group of scientists gathered for a luncheon in one of the attrac tive small restaurants in Weisbaden, Germany. The purpose of the workshop was to bring together interested scientists to discuss the newer developments and the recent advances in the field of phosphate metabolism and the other related minerals. An Organizing Committee made of Shaul G. Massry (USA), Louis V. Avioli (USA), Philippe Bordier (France), Herbert Fleisch (Switzerland), and Eduardo Slatopolsky (USA) was formed. The First Workshop was held in Paris during June 5-6, 1975 and was hosted by Dr. Philippe Bordier. Its proceeding was already published. The Second Workshop took place in Heidelberg during June 28-30, 1976 and was hosted by Dr. Eberhard Ritz. Both of these workshops were extremely successful scientific endeavors, and the need for them was demonstrated by the great interest they generated among the scientific community. The Or ganizing Committee, therefore, decided to continue with the tradi tion to hold additional Workshops annually or every other year.
Author : Jukka K. Heinonen
Publisher : Springer Science & Business Media
ISBN 13 : 9780792374411
Total Pages : 266 pages
Book Rating : 4.3/5 (744 download)
Download or read book Biological Role of Inorganic Pyrophosphate written by Jukka K. Heinonen and published by Springer Science & Business Media. This book was released on 2001-08-31 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Heinonen reviews and critically evaluates the scientific literature on the biological role of inorganic pyrophosphate (PPi ) published from 1940 to the end of 1999. He describes and classifies all known biochemical reactions that produce Ppi; describes and evaluates all published methods used in biological Ppi; and compiles and critically evaluates information on the concentration of PPi (with the conclusion that, contrary to common belief, PPi exists throughout the living world in rather high concentrations). Many reactions in which PPi is used as a biochemical energy source instead of ATP have been described in recent decades, especially in bacteria, protists, and plants. These reactions are evaluated from the bioenergetic and regulatory points of view. Also considered is the possible role of PPi as a source of biochemical energy in the primitive phases of life, before ATP. Data is presented on the regulatory role of PPi in living systems, such as activities of enzymes, fidelity of syntheses of macromolecules, and proliferation of cells. PPi may also regulate the formation and dissolution of bone as well as pathologic calcification of soft tissues and the formation of urinary stones. The formation of calcium pyrophosphate dihydrate crystals in the extracellular fluids of joints cause the disease called pseudogout. Biological Role of Inorganic Pyrophosphate book is a unique and invaluable source of references (about 1120) and summarized data for professionals who study or plan to study the role of PPi in living systems. Many different branches of science (biochemistry, microbiology, bioenergetics, plant physiology, parasitology, evolution, orthopedics, rheumatology) have involvement with PPi. This book sums up available knowledge in one place and will help scientists cross disciplinary boundaries.
Author : Amélia Pilar Rauter
Publisher : Royal Society of Chemistry
ISBN 13 : 1788013867
Total Pages : 307 pages
Book Rating : 4.7/5 (88 download)
Download or read book Carbohydrate Chemistry written by Amélia Pilar Rauter and published by Royal Society of Chemistry. This book was released on 2020-09-17 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of the structure and function of carbohydrates and glycoconjugates remains vital in many fields, notably in medicine and molecular biology. This new volume of Carbohydrate Chemistry contains critical reviews covering the latest findings in both chemical and biological sciences, and demonstrates the interdisciplinary nature of modern carbohydrate research. This book addresses diverse applications that continue to be major challenges for carbohydrate chemists. The oxidative deamination reactions and synthesis of N-acetylneuraminic acid derivatives, ketoheptoses, lipid A and analogs, the fascinating world of complex glycans in the interplay with Siglecs, carbohydrates and regenerative medicine, chemistry for the stereocontrol of glycosylation, and the impact of gold chemistry in carbohydrate research are some of the topics presented in this volume 44, which will certainly benefit any researcher who wishes to learn about the latest developments in the carbohydrate field.
Author : Kanwal Kher
Publisher : CRC Press
ISBN 13 : 1482214636
Total Pages : 1110 pages
Book Rating : 4.4/5 (822 download)
Download or read book Clinical Pediatric Nephrology written by Kanwal Kher and published by CRC Press. This book was released on 2016-11-25 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of a bestseller, this book provides insight from a wide array of international contributors in the field of pediatric nephrology. Copiously illustrated with photomicrographs and clinical diagrams, the third edition reflects current advances in the field. Each chapter contains a set of questions, directed at helping fellows succeed at the American Pediatric Nephrology Board examination. New information for this edition includes changes in treatment options for hyponatremia, and updates on hyperparathyroidism and transplantation. Text boxes highlight important "take home points" throughout the chapters. Clinical Pediatric Nephrology, Third Edition will be a valuable reference for clinicians in nephrology, pediatrics and urology, and any professional involved in the care of children with renal diseases seeking a reliable contemporary text.
Author : E. Buncel
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.:/5 ( download)
Download or read book Heavy Atom Isotope Effects written by E. Buncel and published by . This book was released on 1992 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
