Peripheral Nerve Tissue Engineering and Regeneration

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Author :
Publisher : Springer
ISBN 13 : 9783030210519
Total Pages : 612 pages
Book Rating : 4.2/5 (15 download)

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Book Synopsis Peripheral Nerve Tissue Engineering and Regeneration by : James B. Phillips

Download or read book Peripheral Nerve Tissue Engineering and Regeneration written by James B. Phillips and published by Springer. This book was released on 2022-05-26 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updatable book provides an accessible informative overview of the current state of the art in nerve repair research.The introduction includes history of nerve repair research and establishes key concepts and terminology and will be followed by sections that represent the main areas of interest in the field: (1) Biomaterials, (2) Therapeutic Cells, (3) Drug, Gene and Extracellular Vesicle Therapies, (4) Research Models and (5) Clinical Translation. Each section will contain 3 - 6 chapters, capturing the full breadth of relevant technology. Bringing together diverse disciplines under one overarching theme echoes the multidisciplinary approach that underpins modern tissue engineering and regenerative medicine. Each chapter will be written in an accessible manner that will facilitate interest and understanding, providing a comprehensive single reference source. The updatable nature of the work will ensure that it can evolve to accommodate future changes and new technologies. The main readership for this work will be researchers and clinicians based in academic, industrial and healthcare settings all over the world.

Peripheral Nerve Regeneration

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889632687
Total Pages : 302 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Peripheral Nerve Regeneration by : Giovanna Gambarotta

Download or read book Peripheral Nerve Regeneration written by Giovanna Gambarotta and published by Frontiers Media SA. This book was released on 2019-12-24 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Engineering Neural Tissue from Stem Cells

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Author :
Publisher : Academic Press
ISBN 13 : 0128113863
Total Pages : 226 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Engineering Neural Tissue from Stem Cells by : Stephanie Willerth

Download or read book Engineering Neural Tissue from Stem Cells written by Stephanie Willerth and published by Academic Press. This book was released on 2017-07-05 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications. - Provides readers entering the field with a strong basis of neural tissue engineering processes and real-world applications - Discusses the most current clinical trials and their importance of treating nervous system disorders - Reviews the structure and immune response of the nervous system, including the brain, spinal cord and their present cells - Offers a necessary overview of the natural and synthetic biomaterials used to engineer neural tissue

Modern Concepts of Peripheral Nerve Repair

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Author :
Publisher : Springer
ISBN 13 : 3319523198
Total Pages : 144 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Modern Concepts of Peripheral Nerve Repair by : Kirsten Haastert-Talini

Download or read book Modern Concepts of Peripheral Nerve Repair written by Kirsten Haastert-Talini and published by Springer. This book was released on 2017-06-19 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on posttraumatic repair and reconstruction of peripheral nerves. Written by internationally respected specialists, it provides an overview of the challenges and the latest advances in diagnosis and treatment of traumatic peripheral nerve injuries. It presents an outline of state-of the-art procedures from diagnostics, including newest imaging techniques, over conventional and alternative surgical approaches to clinical follow-up and rehabilitation, including the latest concepts to improve functional recovery. The purely clinical topics are preceded by neuroanatomical principles and neurobiological events related to peripheral nerve transection injuries and followed by an outlook on current experimental developments in the area of biomaterials for artificial nerve grafts and peripheral nerve tissue engineering. Peripheral nerve injuries not only affect the nerve tissue at the site of injury, but also target tissue and parts of the central nervous system. They often have dramatic consequences for patients, including loss of sensory and motor functions combined with paresthesia or pain, and a reduced quality of life and ability to work. An adequate understanding of the procedures for proper decision-making and reconstructing peripheral nerves is therefore essential to ensure optimized functional recovery.

Tissue Engineering Using Ceramics and Polymers

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Author :
Publisher : Elsevier
ISBN 13 : 1845693817
Total Pages : 625 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Tissue Engineering Using Ceramics and Polymers by : Aldo R. Boccaccini

Download or read book Tissue Engineering Using Ceramics and Polymers written by Aldo R. Boccaccini and published by Elsevier. This book was released on 2007-10-31 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated. With its distinguished editors and international team of contributors, Tissue Engineering using Ceramics and Polymers reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. Part one discusses general issues such as ceramic and polymeric biomaterials, scaffolds, transplantation of engineered cells, surface modification and drug delivery. Later chapters review characterisation using x-ray photoelectron spectroscopy and secondary ion mass spectrometry as well as environmental scanning electron microscopy and Raman micro-spectroscopy. Chapters in part two analyse bone regeneration and specific types of tissue engineering and repair such as cardiac, intervertebral disc, skin, kidney and bladder tissue. The book concludes with the coverage of themes such as nerve bioengineering and the micromechanics of hydroxyapatite-based biomaterials and tissue scaffolds. Tissue Engineering using Ceramics and Polymers is an innovative reference for professionals and academics involved in the field of tissue engineering. - An innovative and up-to-date reference for professionals and academics - Environmental scanning electron microscopy is discussed - Analyses bone regeneration and specific types of tisue engineering

Neuroprosthetics

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Author :
Publisher : World Scientific
ISBN 13 : 9789812380227
Total Pages : 1292 pages
Book Rating : 4.3/5 (82 download)

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Book Synopsis Neuroprosthetics by : Kenneth W. Horch

Download or read book Neuroprosthetics written by Kenneth W. Horch and published by World Scientific. This book was released on 2004 with total page 1292 pages. Available in PDF, EPUB and Kindle. Book excerpt: A study of neuroprosthetics. It is broadly divided into three sections which address: neuroanatomy and neurophysiology, biomaterials and biocompatibility, stimulation and recording techniques; clinical applications of neuroprosthetics; and future developments.

Tissue Engineering For The Hand: Research Advances And Clinical Applications

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Author :
Publisher : World Scientific
ISBN 13 : 9814464600
Total Pages : 284 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Tissue Engineering For The Hand: Research Advances And Clinical Applications by : James Chang

Download or read book Tissue Engineering For The Hand: Research Advances And Clinical Applications written by James Chang and published by World Scientific. This book was released on 2010-10-04 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Musculoskeletal applications of tissue engineering will be among the first to achieve widespread clinical use, and the resulting shift in clinical and surgical paradigms will highlight the need for an authoritative text on tissue engineering for musculoskeletal tissues including nerve, bone, tendon, skin, vessels, and cartilage. This book will serve the needs of a large readership including plastic surgeons, orthopedic surgeons, medical residents and medical students, researchers and academic faculty in regenerative medicine and biomedical engineering, and medical device experts. This textbook will serve as the curriculum for undergraduate and graduate courses in biomedical engineering and surgery.Notable contributors to this volume include Antonios G Mikos, PhD; Wei Liu, MD; Yilin Cao, MD; Mark Randolph, MAS; Jennifer Elisseeff, PhD; Geoffrey C Gurtner, MD; Michael T Longaker, MD; and James Chang, MD, all of whom are leaders in tissue engineering research and applications.

Cell Engineering and Regeneration

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Author :
Publisher : Springer
ISBN 13 : 9783319088303
Total Pages : 0 pages
Book Rating : 4.0/5 (883 download)

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Book Synopsis Cell Engineering and Regeneration by : Heinz Redl

Download or read book Cell Engineering and Regeneration written by Heinz Redl and published by Springer. This book was released on 2017-02-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.

Novel Biomaterials for Regenerative Medicine

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Author :
Publisher : Springer
ISBN 13 : 9811309477
Total Pages : 533 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Novel Biomaterials for Regenerative Medicine by : Heung Jae Chun

Download or read book Novel Biomaterials for Regenerative Medicine written by Heung Jae Chun and published by Springer. This book was released on 2018-10-24 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth a wide range of new biomaterials that hold great promise for applications in regenerative medicine. The opening two sections are devoted to biomaterials designed to direct stem cell fate and regulate signaling pathways. Diverse novel functional biomaterials, including injectable nanocomposite hydrogels, electrosprayed nanoparticles, and waterborne polyurethane-based materials, are then discussed. The fourth section focuses on inorganic biomaterials, such as nanobioceramics, hydroxyapatite, and titanium dioxide. Finally, up-to-date information is provided on a wide range of smart natural biomaterials, ranging from silk fibroin-based scaffolds and collagen type I to chitosan, mussel-inspired biomaterials, and natural polymeric scaffolds. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth the latest enabling technologies for regenerative medicine.

Peripheral Nerve Regeneration

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535131656
Total Pages : 226 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Peripheral Nerve Regeneration by : Ana Colette Maurício

Download or read book Peripheral Nerve Regeneration written by Ana Colette Maurício and published by BoD – Books on Demand. This book was released on 2017-05-31 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peripheral nerve injuries are a high-incidence clinical problem that greatly affects patients' quality of life. Despite continuous refinement of microsurgery techniques, peripheral nerve repair still stands as one of the most challenging tasks in neurosurgery, as functional neuromuscular recovery is rarely satisfactory in these patients. Therefore, the improvement of surgical techniques and the clinical application of innovative therapies have been intensively studied worldwide. Direct nerve repair with epineural end-to-end sutures is still the gold standard treatment for severe neurotmesis injuries but only in cases where well-vascularized tension-free coaptation can be achieved. When peripheral nerve injury originates a significant gap between the nerve stumps, nerve grafts are required, with several associated disadvantages. Therefore, the development of scaffolds by tissue engineering can provide efficient treatment alternatives to stimulate optimum clinical outcome. Nerve conduit tailoring involves reaching ideal wall pores, using electrospinning techniques in their fabrication, surface coating with extracellular matrix materials, and adding of growth factors or cell-based therapies, among other possibilities. Also, intraluminal cues are employed such as the filling with hydrogels, inner surface modification, topographical design, and the introduction of neurotrophic factors, antibiotics, anti-inflammatories and other pharmacological agents. A comprehensive state of the art of surgical techniques, tissue-engineered nerve graft scaffolds, and their application in nerve regeneration, the advances in peripheral nerve repair and future perspectives will be discussed, including surgeons' and researchers' own large experience in this field of knowledge.

Nerve Injury and Repair

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Author :
Publisher :
ISBN 13 : 9780443035289
Total Pages : 222 pages
Book Rating : 4.0/5 (352 download)

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Book Synopsis Nerve Injury and Repair by : Göran Lundborg

Download or read book Nerve Injury and Repair written by Göran Lundborg and published by . This book was released on 1988-01-01 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Plastic and Reconstructive Surgery

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Publisher : Springer
ISBN 13 : 1447163354
Total Pages : 634 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Plastic and Reconstructive Surgery by : Maria Z. Siemionow

Download or read book Plastic and Reconstructive Surgery written by Maria Z. Siemionow and published by Springer. This book was released on 2015-01-12 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a paradigm shift in plastic and reconstructive surgery from the interest of developing new surgical techniques into the application of new technologies via research based studies on stem cells, tissue engineering and new field of reconstructive transplantation such as e.g. face, hand or larynx transplants. This approach is relatively novel and introduced to plastic surgery within past decade. Thus there is an urgent need to facilitate access to this new knowledge which was not traditionally a part of plastic surgery curriculum. The most efficient way of introducing these new approaches is via presentation of pertinent to different fields (stem cell, transplantation, nerve regeneration, tissue engineering) experimental models which can be used as a tool to develop technologies of interest by different groups of surgeons. These surgical specialities which will be interested and benefit from the book include: plastic and reconstructive surgeons, microsurgeons, hand surgeons, orthopaedic surgeons, neurosurgeons and transplant surgeons.

Tissue Engineering

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Publisher : Nova Publishers
ISBN 13 : 9781604562934
Total Pages : 342 pages
Book Rating : 4.5/5 (629 download)

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Book Synopsis Tissue Engineering by : Steven J. Barnes

Download or read book Tissue Engineering written by Steven J. Barnes and published by Nova Publishers. This book was released on 2008 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, etc.). Often, the tissues involved require certain mechanical and structural properties for proper function. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bioartificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells to produce tissues. This book presents recent and important research in the field.

Neural Tissue Biomechanics

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Publisher : Springer Science & Business Media
ISBN 13 : 364213890X
Total Pages : 288 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Neural Tissue Biomechanics by : Lynne E. Bilston

Download or read book Neural Tissue Biomechanics written by Lynne E. Bilston and published by Springer Science & Business Media. This book was released on 2011-07-23 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Damage to the central nervous system resulting from pathological mechanical loading can occur as a result of trauma or disease. Such injuries lead to significant disability and mortality. The peripheral nervous system, while also subject to injury from trauma and disease, also transduces physiological loading to give rise to sensation, and mechanotransduction is also thought to play a role in neural development and growth. This book gives a complete and quantitative description of the fundamental mechanical properties of neural tissues, and their responses to both physiological and pathological loading. This book reviews the methods used to characterize the nonlinear viscoelastic properties of central and peripheral neural tissues, and the mathematical and sophisticated computational models used to describe this behaviour. Mechanisms and models of neural injury from both trauma and disease are reviewed from the molecular to macroscopic scale. The book provides a comprehensive picture of the mechanical and biological response of neural tissues to the full spectrum of mechanical loading to which they are exposed. This book provides a comprehensive reference for professionals involved in pre prevention of injury to the nervous system, whether this arises from trauma or disease.

Tissue Engineering for Artificial Organs, 2 Volume Set

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527338632
Total Pages : 762 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Tissue Engineering for Artificial Organs, 2 Volume Set by : Anwarul Hasan

Download or read book Tissue Engineering for Artificial Organs, 2 Volume Set written by Anwarul Hasan and published by John Wiley & Sons. This book was released on 2017-06-19 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

Tissue and Organ Regeneration in Adults

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Author :
Publisher : Springer
ISBN 13 : 1493918656
Total Pages : 344 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Tissue and Organ Regeneration in Adults by : Ioannis V. Yannas

Download or read book Tissue and Organ Regeneration in Adults written by Ioannis V. Yannas and published by Springer. This book was released on 2014-11-21 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation. New to this second edition: New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties The work serves as a comprehensive text and reference for students and practitioners of tissue engineering

Scaffolds in Tissue EngineeringMaterials, Technologies and Clinical Applications

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535136410
Total Pages : 334 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Scaffolds in Tissue EngineeringMaterials, Technologies and Clinical Applications by : Francesco Baino

Download or read book Scaffolds in Tissue EngineeringMaterials, Technologies and Clinical Applications written by Francesco Baino and published by BoD – Books on Demand. This book was released on 2017-12-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials are often designed to act as scaffolds, i.e., 3D porous templates that support and stimulate the growth of healthy tissue and then safely dissolve once they have performed their functions. This book provides a picture of the current state of the art in the field of scaffolds for tissue engineering, highlighting the potential associated to the latest scientific and technological advancements. The former part of the book focuses on the repair of "hard" tissues (primarily bone) by means of bioceramic/glass scaffolds, and the latter deals with the applications of polymeric scaffolds for regenerating "soft" tissues and structures including the peripheral nerve, heart, gastric mucosa and pancreas. Special emphasis is given to the challenges associated to scaffold manufacturing, biomimetic properties and cell-scaffold interactions.