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Therapeutic Drug Monitoring And Clinical Toxicology Of Anti Cancer Drugs
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Book Synopsis Therapeutic Drug Monitoring and Clinical Toxicology of Anti-Cancer Drugs by : Miao Yan
Download or read book Therapeutic Drug Monitoring and Clinical Toxicology of Anti-Cancer Drugs written by Miao Yan and published by Frontiers Media SA. This book was released on 2022-10-26 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Therapeutic drug monitoring and clinical toxicology of anti-cancer drugs, volume II by : Miao Yan
Download or read book Therapeutic drug monitoring and clinical toxicology of anti-cancer drugs, volume II written by Miao Yan and published by Frontiers Media SA. This book was released on 2023-04-04 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology by : Seth Kwabena Amponsah
Download or read book Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology written by Seth Kwabena Amponsah and published by Springer Nature. This book was released on 2022-10-25 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges
Book Synopsis Therapeutic Drug Monitoring by : Amitava Dasgupta
Download or read book Therapeutic Drug Monitoring written by Amitava Dasgupta and published by Elsevier. This book was released on 2024-04-26 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic Drug Monitoring 2nd Edition is an updated reference on TDM analytical techniques in diverse clinical settings. This new edition reviews the exciting new developments in the area, including seven new chapters covering immunoassay design and applications, combined chromatographic techniques in therapeutic monitoring, drug monitoring in alternative specimens, pharmacogenomics of anticancer drugs, pharmacogenomics testing for patient management, selected antifungal agents, pharmacodynamic monitoring, and therapeutic drug monitoring of selected anticoagulants. All remaining chapters in the first edition were thoroughly revised and updated. Therapeutic Drug Monitoring 2nd Edition is the ideal reference for clinical pathologists, pharmacologists, and toxicologists involved with TDM. Scientists working in diagnostic companies, developing reagents for monitoring therapeutic drugs will also find relevant information in this book. Includes new chapters covering antifungal, anticoagulant, and anticancer drugs monitoring Discusses limitations of current immunoassays, new and sophisticated chromatographic techniques, the clinical effectiveness of newer antiretroviral agents, anticonvulsants and antidepressants Provides full coverage of pharmacogenomics and personalized medicine, principles of pharmacokinetics and pharmacodynamics, and the application of biomarkers in TDM
Book Synopsis Anticancer Drug Toxicity by : Hans-Peter Lipp
Download or read book Anticancer Drug Toxicity written by Hans-Peter Lipp and published by CRC Press. This book was released on 1999-04-13 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing the latest findings on the toxicity of a wide range of chemotherapeutic agents, this up-to-the-minute reference offers expert analyses on the pharmacokinetic-pharmacodynamic and pharmacokinetic-toxicodynamic relationships of anticancer compounds. Anticancer Drug Toxicity explores therapeutic drug monitoring (TDM) as a method of maximizing the efficacy, and minimizing the dangers, of chemotherapy presents a vast amount of clinical pharmacokinetic data on cytostatic drugs offers a comprehensive classification of toxicity patterns associated with the use of cytotoxic drugs analyzes the pharmacokinetics of alkylating agents, platinum compounds, anthracyclines, antimetabolites, semisynthetic podophyllotoxin- and camptothecin derivatives, mitotic inhibitors, and other cytotoxic agents highlights the pharmacogenetics of 6-mercaptopurine and its clinical significance explicates toxicity in relation to the lungs, kidneys, heart, and gonads examines disorders caused by asparaginase preparations reviews types of secondary malignancy such as leukemias, ovarian cancer, testicular cancer, breast cancer, secondary solid neoplasias, and Hodgkin's disease clarifies the understanding of toxicity as a crucial element in supportive management of cancer therapy and more! An enormously practical guide for everyday clinical practice, as well as a source of inspiration for further research in the field, Anticancer Drug Toxicity is an invaluable reference for clinical and medical oncologists; hospital, industrial, and clinical pharmacologists and pharmacists; toxicologists; pharmaceutical chemists; radiologists; and graduate and medical school students in these disciplines.
Book Synopsis Handbook of Drug Monitoring Methods by : Amitava Dasgupta
Download or read book Handbook of Drug Monitoring Methods written by Amitava Dasgupta and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.
Book Synopsis Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology by : Irving Sunshine
Download or read book Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology written by Irving Sunshine and published by CRC Press. This book was released on 2023-06-14 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr
Book Synopsis Anticancer Drug Development Guide by : Beverly A. Teicher
Download or read book Anticancer Drug Development Guide written by Beverly A. Teicher and published by Springer Science & Business Media. This book was released on 2004-02-01 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique volume traces the critically important pathway by which a "molecule" becomes an "anticancer agent. " The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these "anticancer" molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening methods. The National Cancer Institute's high-throughput, in vitro disease-specific screen with 60 or more human tumor cell lines is used to search for molecules with novel mechanisms of action or activity against specific phenotypes. The Human Tumor Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of cells that more nearly resemble the human disease. There is no doubt that the greatest successes of traditional chemotherapy have been in the leukemias and lymphomas. Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of "antileukemia" agents, but that other tumor models would be needed to discover drugs active against solid tumors.
Book Synopsis Advances in Chromatographic Techniques for Therapeutic Drug Monitoring by : Amitava Dasgupta
Download or read book Advances in Chromatographic Techniques for Therapeutic Drug Monitoring written by Amitava Dasgupta and published by CRC Press. This book was released on 2009-10-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for implementing preferred gas and liquid chromatographic methods, Advances in Chromatographic Techniques for Therapeutic Drug Monitoring is a comprehensive reference describing the theory and application of therapeutic drug monitoring in clinical laboratories. Edited by a distinguished authority in the field and containing contributions from a variety of experts, the book discusses preanalytical variables, the pitfalls of immunoassays, tandem mass spectrometry, issues related to pain management and herbal supplements, and therapeutic drug monitoring for a range of medications, including: Anticonvulsants Digitalis Cardioactive drugs Antidepressants Immunosuppressants Anti-cancer drugs Vancomycin and aminoglycosides Antibiotics Antiretroviral drugs Nonnarcotic analgesics Anti-inflammatory drugs Examing older and newer drugs, the book contains detailed discussions on the rationale for therapeutic drug monitoring of each class of drugs, along with their basic pharmacology and toxicology. An extensive list of references is provided at the end of each chapter so that those interested in implementing a new drug assay can find the most appropriate method for the intended drug.
Book Synopsis Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography by : Steven H.Y. Wong
Download or read book Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography written by Steven H.Y. Wong and published by Routledge. This book was released on 2017-09-19 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.
Book Synopsis Therapeutic Drug Monitoring and Clinical Biochemistry by : Mike Hallworth
Download or read book Therapeutic Drug Monitoring and Clinical Biochemistry written by Mike Hallworth and published by AACC Press. This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text considers the close inter-relationship of therapeutic drug monitoring and clinical biochemistry. It covers principles of TDM, looking at drug dosage and effect; clinical monitoring and pharmacokinetics; interpretation and response; and near-patient testing. It also includes information on methodology, dosage prediction, drug structure, sampling requirements and target range. The drugs covered include anti-convulsants; aminoglycosides; lithium; anti-arrythmics; xanthines; cyclosporine; methotrexate; and tricyclics. The work also contains case studies.
Book Synopsis Therapeutic Drug Monitoring Clinical Guide by : William E. Evans
Download or read book Therapeutic Drug Monitoring Clinical Guide written by William E. Evans and published by . This book was released on 1988 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology by : Irving Sunshine
Download or read book Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology written by Irving Sunshine and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr
Book Synopsis Therapeutic Drug Monitoring by : Amitava Dasgupta
Download or read book Therapeutic Drug Monitoring written by Amitava Dasgupta and published by Academic Press. This book was released on 2012-06-07 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential resource on the current practice of therapeutic drug monitoring in improving patient safety. Includes both the technical and clinical issues associated with therapeutic drug monitoring Discusses the utility of therapeutic drug monitoring of newer drugs such as antiretroviral agents, anticonvulsants, antidepressants etc. Provides up-to-date information on issues in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants Covers important content on the limitations of commercially available immunoassays (chemical tests) for therapeutic drug monitoring and additional analytical techniques
Book Synopsis Therapeutic Drug Monitoring Data by : Amitava Dasgupta
Download or read book Therapeutic Drug Monitoring Data written by Amitava Dasgupta and published by Academic Press. This book was released on 2019-09-14 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab. Serves as a ready resource of information for commonly monitored drugs Presents a useful, quick guide for those making decisions related to monitoring and interpretation of results Provides concise, easily digestible content for clinical laboratory scientists, toxicologists and clinicians
Book Synopsis Clinical Challenges in Therapeutic Drug Monitoring by : William Clarke
Download or read book Clinical Challenges in Therapeutic Drug Monitoring written by William Clarke and published by Elsevier. This book was released on 2016-05-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations.
Book Synopsis Therapeutic Drug Monitoring by : B. Widdop
Download or read book Therapeutic Drug Monitoring written by B. Widdop and published by . This book was released on 1985 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
