Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Theories Of Immune Networks
Download Theories Of Immune Networks full books in PDF, epub, and Kindle. Read online Theories Of Immune Networks ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Theories of Immune Networks by : Henri Atlan
Download or read book Theories of Immune Networks written by Henri Atlan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a long time, immunology has been dominated by the idea of a simple linear cause-effect relationship between the exposure to an antigen and the production of specific antibodies against that antigen. Clonal selection was the name of the theory based on this idea and it has provided the main concepts to account for the known features of the immune response. More recently, immunologists have discovered a wealth of new facts, in the form of different regulatory cells (helpers, suppressors, antigen presenting cells), genetic determinations of immune responses such as those involved in graft re jections, different molecular structures responsible for intercellular interactions such as interleukins, cytokins, idiotype-antiidiotype recognition and others. While furthering our understanding of the local interactions (molecular and cellular) in volved in the immune response, these discoveries have led to a questioning of the simplicities of the classical clonal selection theory. It is clear today that every single immune response is a cooperative phenomenon involving several different molecular and cellular interactions taking place in a coupled manner. In addition, cross reactivity to different antigens has shown that responses of the whole im mune system to different antigens are not completely isolated from one another and that the history of encounters with different antigens plays a crucial role in the maturation of the whole system. Thus, problems of complexity, generation of di versity and self-organization have entered the field of immunology.
Book Synopsis The Quantal Theory of Immunity by : Kendall A. Smith
Download or read book The Quantal Theory of Immunity written by Kendall A. Smith and published by World Scientific. This book was released on 2010 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how the immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none (quantal) manner. To date, there has not been a complete description of the immune system and its cells and molecules, primarily because most of the information has accumulated only in the last 40 years and our understanding has been expanding rapidly only in the last 20 years. It is now clear that the cells have evolved a way to ?count? the number of foreign antigenic molecular ?hits?, and they only react when a critical number of events have accumulated. Subsequently, control over the reaction is transferred to a systemic lymphocytotrophic hormone system that determines the tempo, magnitude and duration of the immune reaction. This book explains in detail how the immune system, cells and molecules work for the first time. With this understanding as a basis, the pathogenesis of autoimmunity can now be understood as a mutational usurpation of the genes encoding molecules that participate in a sensitive feedback regulatory control of the immune reaction. By comparison, malignant transformation is understood as a mutational usurpation of the genes encoding the molecules that control the quantal decision to proliferate, so that normal ligand/receptor cell growth control is circumvented. This molecular understanding of the immune system is especially important for the design of successful vaccines, and also explains why vaccines fail.
Book Synopsis Immunological Computation by : Dipankar Dasgupta
Download or read book Immunological Computation written by Dipankar Dasgupta and published by CRC Press. This book was released on 2008-09-12 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearly, nature has been very effective in creating organisms that are capable of protecting themselves against a wide variety of pathogens such as bacteria, fungi, and parasites. The powerful information-processing capabilities of the immune system, such as feature extraction, pattern recognition, learning, memory, and its distributive nature prov
Book Synopsis Portrait of the Immune System by : Ivan Lefkovits
Download or read book Portrait of the Immune System written by Ivan Lefkovits and published by World Scientific. This book was released on 1996 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the published work of Nobel Laureate Niels Kaj Jerne, this book shows how he developd his ideas. The book is a compilation of his published work, but in fact it is much more than that. Whether the reader wants to read the book systematically, or only browse, it opens a fascinating world of hypotheses, theories, facts and vistas. His selection theory, his view of how immunological diversity is created, and his concept of lymphocytes interacting as a network, reveals Jerne's revolutionary spirit. The book ought to be a rich source of inspiration for everyone interested in science and how science is made.
Book Synopsis Immunity-Based Systems by : Yoshiteru Ishida
Download or read book Immunity-Based Systems written by Yoshiteru Ishida and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: After I came to know Jerne's network theory on the immune system, I became fascinated with the immune system as an information system. The main pro totypes for biological information systems have been the neural systems and the brain. However, the immune system is not only an interesting informa tion system but it may provide a design paradigm for artificial information systems. With such a consideration, I initiated a project titled "autonomous decentralized recognition mechanism of the immune network and its applica tion to distributed information processing" in 1990 under a Grant-in-Aid for Scientific Research on a Priority Area ("Autonomous Distributed Systems") supported by the Ministry of Education, Science, and Culture. During the project, I promoted the idea that the immune system could be a prototype of autonomous distributed systems. After the project, we organized an international workshop on immunity based systems in 1996 in conjunction with the International Conference on Multi-Agent Systems held in Kyoto, Japan. Recently, there have been several international conferences related to topics inspired by the immune system and an increasing number of research papers related to the topic. In writing this book, a decade after the project, I still believe that the immune system can be a prototype, a compact but sophisticated system that nature has shown us for building artificial information systems in this network age of the twenty-first century.
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis Theoretical Immunology, Part One by : Alan S. Perelson
Download or read book Theoretical Immunology, Part One written by Alan S. Perelson and published by CRC Press. This book was released on 2018-03-05 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology". The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.
Book Synopsis The Network Collective by : Klaus Eichmann
Download or read book The Network Collective written by Klaus Eichmann and published by Springer Science & Business Media. This book was released on 2008-11-18 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The network paradigm dominated immunological research from the early 1970s to the late 1980s. The originator, Niels Jerne, hypothesized that the vast diversity of antibodies in each individual forms a network of mutual "idiotypic" recognition, thus regulating the immune system. In context of emerging concepts of systems biology such as cybernetics and autopoesis, the "Eigenbehavior" of the immune system fascinated an entire generation of young immunologists. But fascination led to experimental errors and overinterpretation, eventually magnifying the immune system from a mere infection-fighting device to a substrate of personality and individuality. As a result, what initially appeared as an exciting new perspective of the immune system is now viewed as a scientific vagary, and is largely abandoned. The author, himself a participant in the network vagary, begins with a description of the leading theoretical concepts on fact finding in science. This is followed by a historical account of the rise and fall of the network paradigm, complemented by personal interviews with some of the prominent protagonists. By comparing the network paradigm to other, more lasting concepts in life science, the author develops a general perspective on how solid knowledge is derived from error-prone scientific methodology, namely by exposure of scientific notions to the scrutiny of reality.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunity written by Alfred I. Tauber and published by Oxford University Press. This book was released on 2017-01-02 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern immunology traditionally conceives of the immune system as providing defense against pathogens. Alfred I. Tauber criticizes this conception of immunity as too narrow, because it discounts much of the immune system's other normal functions. These include active tolerance of nutritional exchanges with the environment and the stabilization of cooperative relationships with resident micro-organisms. An expanded account extends immunity's functional role from singular 'defense' to broadened discernment of environmental 'exchange.' This ecological perspective has profound theoretical implications, for the basic notion of immune identity is reconfigured: highlighting the organism as a holobiont (a consortium of diverse organisms living in cooperative relationships) challenges prevailing concepts of individuality and the self/nonself dichotomy heretofore organizing immune theory. Indeed, if theoretical interest is focused on the challenges of maintaining immune balance in the full ecological context of the organism, then immune regulation assumes new complexity. Tauber maintains that the key to unravelling that puzzle requires a critical re-assessment of the cognitive processes that underlie immune effector functions. Accordingly, he provides the outline of a re-formulated 'cognitive paradigm' that dispenses with agent-based models and adopts an ecologically conceived understanding of perception and information processing. The implications of this revised configuration of immunity and its deconstructed notions of individuality and selfhood have wide significance for philosophers and life scientists working in immunology, ecology, and the cognitive sciences.
Book Synopsis Artificial Immune Systems and Their Applications by : Dipankar Dasgupta
Download or read book Artificial Immune Systems and Their Applications written by Dipankar Dasgupta and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a pioneering work on the emerging field of artificial immune systems-highly distributed systems based on the principles of the natural system. Like artificial neural networks, artificial immune systems can learn new information and recall previously learned information. This book provides an overview of artificial immune systems, explaining its applications in areas such as immunological memory, anomaly detection algorithms, and modeling the effects of prior infection on vaccine efficacy.
Book Synopsis Introduction to Immunology by : John W. Kimball
Download or read book Introduction to Immunology written by John W. Kimball and published by MacMillan Publishing Company. This book was released on 1990 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Theoretical Immunology, Part Two by : Alan S. Perelson
Download or read book Theoretical Immunology, Part Two written by Alan S. Perelson and published by CRC Press. This book was released on 2018-02-19 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology." The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.
Book Synopsis The Immune Self by : Alfred I. Tauber
Download or read book The Immune Self written by Alfred I. Tauber and published by Cambridge University Press. This book was released on 1994 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune Self is the first extended philosophical critique of immunology.
Book Synopsis Systems Theory in Immunology by : C. Bruni
Download or read book Systems Theory in Immunology written by C. Bruni and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collects the contributions presented at the "Working Conference on System Theory in Immunology", held in Rome, May 1978. The aim of the Conference was to bring together immunologists on one side and experts in system theory and applied mathematics on the other, in order to identify problems of common interest and to establish a network of joint effort toward their solution. The methodologies of system theory for processing experimental data and for describing dynamical phenomena could indeed contribute significantly to the under standing of basic immunological facts. Conversely, the complexity of experimental results and of interpretative models should stimulate mathematicians to formulate new problems and to design appropriate procedures of analysis. The multitude of scientific publications in theoretical biology, appeared in recent years, confirms this trend and calls for extensive interaction between mat- matics and immunology. The material of this volume is divided into five sections, along the scheme of the Conference program.
Book Synopsis Network Theory for the Immune System by : U. Behn
Download or read book Network Theory for the Immune System written by U. Behn and published by . This book was released on 1988 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Historical Perspective on Evidence-Based Immunology by : Edward J. Moticka
Download or read book A Historical Perspective on Evidence-Based Immunology written by Edward J. Moticka and published by Newnes. This book was released on 2015-11-25 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. - Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles - Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology - Presents concepts such as the division of lymphocytes into functionally different populations in their historical context - Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
