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Author : A. Whiting
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (593 download)
Download or read book The Total Synthesis of Beta-lactam Derivatives written by A. Whiting and published by . This book was released on 1984 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alle Bruggink
Publisher : Springer Science & Business Media
ISBN 13 : 9401008507
Total Pages : 328 pages
Book Rating : 4.4/5 (1 download)
Download or read book Synthesis of β-Lactam Antibiotics written by Alle Bruggink and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Author : Barry A. Bunin
Publisher : Elsevier
ISBN 13 : 0080542409
Total Pages : 341 pages
Book Rating : 4.0/5 (85 download)
Download or read book The Combinatorial Index written by Barry A. Bunin and published by Elsevier. This book was released on 1998-04-15 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of combinatorial solid-phase methods, access to information has become one of the main barriers facing a synthetic chemist who is contemplating a combinatorial approach to a medicinal chemistry problem. The Combinatorial Index is an answer to that problem. This compendium of methods from the primary literature provides quick and convenient access to reliable synthetic transformations as well as information on linkers and analytical methods. Each synthetic procedure is preceded by a section entitled"Points of Interest,"which highlights the strengths and weaknesses of the various studies. The index also covers the use of solution-based synthesis for the generation of molecular diversity. - Organized for rapid retrieval of published information on classes of synthetic transformations, linkers, and analytical methods - Serves as a laboratory manual for bench chemists - Includes a chapter on linkers to assist in choice of linking strategy - Discusses strengths and limitations of the various methods - Contains a structural index showing functional group transformations in solid-phase synthesis
Author : Maghar S. Manhas
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.F/5 ( download)
Download or read book Beta-lactams: Natural and Synthetic written by Maghar S. Manhas and published by John Wiley & Sons. This book was released on 1971 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Author : Simon Baker
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (595 download)
Download or read book Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel [beta]-lactam Antibiotics written by Simon Baker and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David F. Corbett
Publisher :
ISBN 13 :
Total Pages : 189 pages
Book Rating : 4.:/5 (131 download)
Download or read book The Synthesis of B-lactam Derivatives written by David F. Corbett and published by . This book was released on 1974 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Asymmetric Synthesis of [beta]-lactam Derivatives PDF Online Free](https://books.google.com/books/content/images/frontcover/YzsrOAAACAAJ?fife=w200-h370)
Author : Chun Ma
Publisher :
ISBN 13 :
Total Pages : 342 pages
Book Rating : 4.:/5 (283 download)
Download or read book Asymmetric Synthesis of [beta]-lactam Derivatives written by Chun Ma and published by . This book was released on 1992 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bimal K. Banik
Publisher : Springer
ISBN 13 : 3319556215
Total Pages : 423 pages
Book Rating : 4.3/5 (195 download)
Download or read book Beta-Lactams written by Bimal K. Banik and published by Springer. This book was released on 2017-05-11 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
Author : Simon Peter Baker
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (99 download)
Download or read book Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel Β-lactam Antibiotics written by Simon Peter Baker and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Simon Peter Baker
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (99 download)
Download or read book Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel Β-lactam Antibiotics written by Simon Peter Baker and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Arthur Greenberg
Publisher :
ISBN 13 :
Total Pages : 532 pages
Book Rating : 4.3/5 (91 download)
Download or read book Primer on Kidney Diseases written by Arthur Greenberg and published by . This book was released on 2001 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new publication of the National Kidney Foundation offers an up-to-date review of kidney disease, fluid and electrolyte disorders, hypertension, dialysis, and renal transplantation. It summarizes key information of practical value to primary care physicians, family practitioners, internists, house staff, medical students, nephrologists, and other professionals providing health care to patients with kidney disease. Key Features *Contains authoratative, up-to-date information from the National Kidney Foundation * User-friendly, in-depth summaries of major areas in nephrology * Practical approach to diagnosis and management of kidney disease
Author : John W. Kennington
Publisher :
ISBN 13 :
Total Pages : 180 pages
Book Rating : 4.:/5 (299 download)
Download or read book I. Approaches to the Synthesis of Nogalamycin and Related Substances written by John W. Kennington and published by . This book was released on 1993 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Author : Robert B. Morin
Publisher :
ISBN 13 : 9780125063029
Total Pages : 430 pages
Book Rating : 4.0/5 (63 download)
Download or read book Chemistry and Biology of [beta]-lactam Antibiotics written by Robert B. Morin and published by . This book was released on 1982 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gabor Lukacs
Publisher : Springer Science & Business Media
ISBN 13 : 3642756174
Total Pages : 808 pages
Book Rating : 4.6/5 (427 download)
Download or read book Recent Progress in the Chemical Synthesis of Antibiotics written by Gabor Lukacs and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antibiotics in the treatment by antibacterial and antifungal chemo therapy, has become standard practice since the end of World War Two and has had an enormous impact on healthcare throughout the world. Compounds belonging to this class have also reached an important place in the medical treatment of human cancer. Although, the discovery of most of these agents came from more or less sophisticated screening programs of soil microrganisms, many of the important antibiotics used today in clinical practice are derived from the original biosynthetic products by the application of often novel and generally elaborated chemical synthetic methodologies. In fact the antibiotics have represented (and still represent) for a generation of organic chemists an endless source of molecular structures whose varied assemblage of carbon atom backbones and chemical functions was beyond any possibility of imagination. Perhaps a similar repertoire of chemotypes was formerly offered by the natural products, namely the alkaloids, the terpenes, the vitamins and hormones as well as the pigments of the animal and plant kingdoms, albeit the chemical arrange ments of the antibiotic molecules appeared much more surprising and diverse to the admiring eyes of cultivated organic chemists. The idea of this book, certainly a landmark in the field, came during the Symposium of EUCHEM on Chemical Synthesis of Antibiotics, that was held at Aussois in Savoy, France (May 2-6, 1988), the initiative being taken by Gabor Lukacs to whom Masaji Ohno readily associated as a co-editor.
Author : Roger Finch
Publisher : OUP Oxford
ISBN 13 : 0191628654
Total Pages : 409 pages
Book Rating : 4.1/5 (916 download)
Download or read book Antimicrobial Chemotherapy written by Roger Finch and published by OUP Oxford. This book was released on 2012-01-05 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.
Author : Derek G. Waller
Publisher : Elsevier Health Sciences
ISBN 13 : 0702055034
Total Pages : 741 pages
Book Rating : 4.7/5 (2 download)
Download or read book Medical Pharmacology and Therapeutics E-Book written by Derek G. Waller and published by Elsevier Health Sciences. This book was released on 2013-08-07 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice
Author : José-Luis Capelo-Martínez
Publisher : John Wiley & Sons
ISBN 13 : 1119282527
Total Pages : 730 pages
Book Rating : 4.1/5 (192 download)
Download or read book Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and published by John Wiley & Sons. This book was released on 2019-09-24 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
