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Author : P. Christine Ackroyd
Publisher :
ISBN 13 :
Total Pages : 502 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Thermodynamic Sources of Affinity and Sequence-specificity written by P. Christine Ackroyd and published by . This book was released on 2001 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 902 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2007 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Karen M. Gooding
Publisher : CRC Press
ISBN 13 : 9780203911594
Total Pages : 806 pages
Book Rating : 4.9/5 (115 download)
Download or read book Hplc Of Biological Macro- Molecules, Revised And Expanded written by Karen M. Gooding and published by CRC Press. This book was released on 2002-01-08 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised to reflect the innovations in HPLC from the past decade, this authoritative reference presents practical strategies for the evaluation and analysis of proteins, peptides, and polynucleotides. Offering class-specific applications for the characterization and fractionation of biological macromolecules, the book contains material on organic supports, size exclusion, ion exchange, hydrophobic interaction, and metal interaction chromatography. Leading experts summarize specialized detection systems, provides discussions on the chemical and biological properties of specific biomolecules, include detailed guidelines for the development of analytical techniques, and more.
Author : Michael J. Waring
Publisher : Royal Society of Chemistry
ISBN 13 : 1782629920
Total Pages : 432 pages
Book Rating : 4.7/5 (826 download)
Download or read book DNA-targeting Molecules as Therapeutic Agents written by Michael J. Waring and published by Royal Society of Chemistry. This book was released on 2018-03-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been remarkable advances towards discovering agents that exhibit selectivity and sequence-specificity for DNA, as well as understanding the interactions that underlie its propensity to bind molecules. This progress has important applications in many areas of biotechnology and medicine, notably in cancer treatment as well as in future gene targeting therapies. The editor and contributing authors are leaders in their fields and provide useful perspectives from diverse and interdisciplinary backgrounds on the current status of this broad area. The role played by chemistry is a unifying theme. Early chapters cover methodologies to evaluate DNA-interactive agents and then the book provides examples of DNA-interactive molecules and technologies in development as therapeutic agents. DNA-binding metal complexes, peptide and polyamide–DNA interactions, and gene targeting tools are some of the most compelling topics treated in depth. This book will be a valuable resource for postgraduate students and researchers in chemical biology, biochemistry, structural biology and medicinal fields. It will also be of interest to supramolecular chemists and biophysicists.
Author : David B. Allison
Publisher : CRC Press
ISBN 13 : 1420028790
Total Pages : 391 pages
Book Rating : 4.4/5 (2 download)
Download or read book DNA Microarrays and Related Genomics Techniques written by David B. Allison and published by CRC Press. This book was released on 2005-11-14 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considered highly exotic tools as recently as the late 1990s, microarrays are now ubiquitous in biological research. Traditional statistical approaches to design and analysis were not developed to handle the high-dimensional, small sample problems posed by microarrays. In just a few short years the number of statistical papers providing approaches
Author : Melissa J. Bobeck
Publisher :
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.3/5 (91 download)
Download or read book Binding Site Structure and Conformational Dynamics in the Sequence-Specific Recognition of SsDNA by an Autoantibody written by Melissa J. Bobeck and published by . This book was released on 2006 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Thomas A. Steitz
Publisher : CUP Archive
ISBN 13 : 9780521414890
Total Pages : 108 pages
Book Rating : 4.4/5 (148 download)
Download or read book Structural Studies of Protein-Nucleic Acid Interaction written by Thomas A. Steitz and published by CUP Archive. This book was released on 1993-09-16 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this 1993 text, Nobel Prize winner Professor Steitz reviews the wide-ranging research in structural studies of DNA-binding proteins and their complexes with DNA. The author clearly and concisely describes the uses of techniques in molecular genetics, DNA synthesis, protein crystallography and nuclear magnetic response.
Author :
Publisher :
ISBN 13 :
Total Pages : 816 pages
Book Rating : 4.3/5 (91 download)
Download or read book American Doctoral Dissertations written by and published by . This book was released on 2000 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael L. Johnson
Publisher : Academic Press
ISBN 13 : 0123812682
Total Pages : 409 pages
Book Rating : 4.1/5 (238 download)
Download or read book Biothermodynamics written by Michael L. Johnson and published by Academic Press. This book was released on 2011 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last several years there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.
Author :
Publisher : Academic Press
ISBN 13 : 0123812690
Total Pages : 408 pages
Book Rating : 4.1/5 (238 download)
Download or read book Biothermodynamics, Part C written by and published by Academic Press. This book was released on 2010-12-28 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. Biothermodynamics, Part C presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. The use of thermodynamics in biological research is used as an “energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well. Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules Provides a "must-have" methods volume that keeps MIE buyers and online subscribers up-to-date with the latest research Offers step-by-step lab instructions, including necessary equipment, from a global research community
Author : Monika Fuxreiter
Publisher : Springer Science & Business Media
ISBN 13 : 1461406595
Total Pages : 210 pages
Book Rating : 4.4/5 (614 download)
Download or read book Fuzziness written by Monika Fuxreiter and published by Springer Science & Business Media. This book was released on 2012-03-07 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detailed characterization of fuzzy interactions will be of central importance for understanding the diverse biological functions of intrinsically disordered proteins in complex eukaryotic signaling networks. In this volume, Peter Tompa and Monika Fuxreiter have assembled a series of papers that address the issue of fuzziness in molecular interactions. These papers provide a broad overview of the phenomenon of fuzziness and provide compelling examples of the central role played by fuzzy interactions in regulation of cellular signaling processes and in viral infectivity. These contributions summarize the current state of knowledge in this new field and will undoubtedly stimulate future research that will further advance our understanding of fuzziness and its role in biomolecular interactions.
Author : Roger Gregory
Publisher : CRC Press
ISBN 13 : 1040282512
Total Pages : 596 pages
Book Rating : 4.0/5 (42 download)
Download or read book Protein-Solvent Interactions written by Roger Gregory and published by CRC Press. This book was released on 2024-11-01 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work covers advances in the interactions of proteins with their solvent environment and provides fundamental physical information useful for the application of proteins in biotechnology and industrial processes. It discusses in detail structure, dynamic and thermodynamic aspects of protein hydration, as well as proteins in aqueous and organic solvents as they relate to protein function, stability and folding.
Author : Daniel J. Graham
Publisher : CRC Press
ISBN 13 : 0429650523
Total Pages : 292 pages
Book Rating : 4.4/5 (296 download)
Download or read book Invitation to Protein Sequence Analysis Through Probability and Information written by Daniel J. Graham and published by CRC Press. This book was released on 2019-02-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the remarkable information correspondences and probability structures of proteins. Correspondences are pervasive in biochemistry and bioinformatics: proteins share homologies, folding patterns, and mechanisms. Probability structures are just as paramount: folded state graphics reflect Angstrom-scale maps of electron density. The author explores protein sequences (primary structures), both individually and in sets (systems) with the help of probability and information tools. This perspective will enhance the reader’s knowledge of how an important class of molecules is designed and put to task in natural systems, and how we can approach class members in hands-on ways.
Author : Jurriaan Huskens
Publisher : John Wiley & Sons
ISBN 13 : 1119143462
Total Pages : 434 pages
Book Rating : 4.1/5 (191 download)
Download or read book Multivalency written by Jurriaan Huskens and published by John Wiley & Sons. This book was released on 2018-02-05 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.
Author : M. Michael Gromiha
Publisher : Academic Press
ISBN 13 : 0123884241
Total Pages : 349 pages
Book Rating : 4.1/5 (238 download)
Download or read book Protein Bioinformatics written by M. Michael Gromiha and published by Academic Press. This book was released on 2011-04-21 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most pressing tasks in biotechnology today is to unlock the function of each of the thousands of new genes identified every day. Scientists do this by analyzing and interpreting proteins, which are considered the task force of a gene. This single source reference covers all aspects of proteins, explaining fundamentals, synthesizing the latest literature, and demonstrating the most important bioinformatics tools available today for protein analysis, interpretation and prediction. Students and researchers of biotechnology, bioinformatics, proteomics, protein engineering, biophysics, computational biology, molecular modeling, and drug design will find this a ready reference for staying current and productive in this fast evolving interdisciplinary field. - Explains all aspects of proteins including sequence and structure analysis, prediction of protein structures, protein folding, protein stability, and protein interactions - Presents a cohesive and accessible overview of the field, using illustrations to explain key concepts and detailed exercises for students.
Author : John E. Leffler
Publisher : Courier Corporation
ISBN 13 : 9780486660684
Total Pages : 500 pages
Book Rating : 4.6/5 (66 download)
Download or read book Rates and Equilibria of Organic Reactions as Treated by Statistical, Thermodynamic, and Extrathermodynamic Methods written by John E. Leffler and published by Courier Corporation. This book was released on 1989-01-01 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Graduate-level text stresses extrathermodynamic approach to quantitative prediction and constructs a logical framework that encompasses and classifies all known extrathermodynamic relationships. Numerous figures and tables. Author and Subject Indexes.
Author : Joanne Cleary
Publisher :
ISBN 13 :
Total Pages : 528 pages
Book Rating : 4.3/5 (91 download)
Download or read book Role of Binding Site Residues in the Sequence-specific Recognition of SsDNA by an Autoantibody written by Joanne Cleary and published by . This book was released on 2002 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
