Translational Pain Research

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Author :
Publisher : CRC Press
ISBN 13 : 1439812101
Total Pages : 458 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Translational Pain Research by : Lawrence Kruger

Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

Advances in Vagal Afferent Neurobiology

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Publisher : CRC Press
ISBN 13 : 0203492315
Total Pages : 556 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis Advances in Vagal Afferent Neurobiology by : Bradley J. Undem

Download or read book Advances in Vagal Afferent Neurobiology written by Bradley J. Undem and published by CRC Press. This book was released on 2005-06-01 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking a comprehensive approach in which all aspects of the vagal afferent system are considered, from the terminals in the visceral tissues to the neural pathways within the central nervous system, this extensive text reviews the development, neurochemistry, anatomy, biophysics, pharmacology, and physiology of the vagal afferent nerves. The author

Neurophenotypes

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Publisher : Springer
ISBN 13 : 1461438462
Total Pages : 310 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Neurophenotypes by : Vinoth Jagaroo

Download or read book Neurophenotypes written by Vinoth Jagaroo and published by Springer. This book was released on 2017-02-24 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interest in ‘biomarkers’ seen across a spectrum of biomedical disciplines reflects the rise of molecular biology and genetics. A host of ‘omics’ disciplines in addition to genomics, marked by multidimensional data and complex analyses, and enabled by bioinformatics, have pushed the trajectory of biomarker development even further. They have also made more tractable the complex mappings of genotypes to phenotypes – genome-to-phenome mapping – to which the concept of a biomarker is central. Genomic investigations of the brain are beginning to reveal spectacular associations between genes and neural systems. Neural and cognitive phenomics are considered a necessary complement to genomics of the brain. Other major omics developments such as connectomics, the comprehensive mapping of neurons and neural networks, are heralding brain maps of unprecedented detail. Such developments are defining a new era of brain science. And in this new research environment, neural systems and cognitive operations are pressed for new kinds of definitions – that facilitate brain-behavioral alignment in an omics operating environment. This volume explores the topic of markers framed around the constructs of cognitive and neural systems. ‘Neurophenotype’ is a term adopted to describe a neural or cognitive marker that can be scientifically described within an associative framework – and while the genome-to-phenome framework is the most recognized of these, epigenetics and non-gene-regulated neural dynamics also suggest other frameworks. In either case, the term neurophenotype defines operational constructs of brain-behavioral domains that serve the integration of these domains with neuroscientific and omics models of the brain. The topic is critically important to psychiatry and neuropsychology: Neurophenotypes offer a ‘format’ and a ‘language’ by which psychiatry and neuropsychology can be in step with the brain sciences. They also bring a new challenge to the clinical neurosciences in terms of construct validation and refinement. Topics covered in the volume include: Brain and cognition in the omics era Phenomics, connectomics, and Research Domain Criteria Circuit-based neurophenotypes, and complications posed by non-gene regulated factors The legacy of the endophenotype concept – its utility and limitations Various potential neurophenotypes of relevance to clinical neuroscience, including Response Inhibition, Fear Conditioning and Extinction, Error Processing, Reward Dependence and Reward Deficiency, Face Perception, and Language Phenotypes Dynamic (electrophysiological) and computational neurophenotypes The challenge of a cultural shift for psychiatry and neuropsychology The volume may be especially relevant to researchers and clinical practitioners in psychiatry and neuropsychology and to cognitive neuroscientists interested in the intersection of neuroscience with genomics, phenomics and other omics disciplines.

Fetal and Neonatal Lung Development

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1316665178
Total Pages : pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Fetal and Neonatal Lung Development by : Alan H. Jobe

Download or read book Fetal and Neonatal Lung Development written by Alan H. Jobe and published by Cambridge University Press. This book was released on 2016-04-18 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.

Murray and Nadel's Textbook of Respiratory Medicine E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1437735533
Total Pages : 2457 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Murray and Nadel's Textbook of Respiratory Medicine E-Book by : Robert J. Mason

Download or read book Murray and Nadel's Textbook of Respiratory Medicine E-Book written by Robert J. Mason and published by Elsevier Health Sciences. This book was released on 2010-06-09 with total page 2457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Murray and Nadel’s Textbook of Respiratory Medicine has long been the definitive and comprehensive pulmonary disease reference. Robert J. Mason, MD now presents the fifth edition in full color with new images and highlighted clinical elements. The fully searchable text is also online at www.expertconsult.com, along with regular updates, video clips, additional images, and self-assessment questions. This new edition has been completely updated and remains the essential tool you need to care for patients with pulmonary disease. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Master the scientific principles of respiratory medicine and its clinical applications. Work through differential diagnosis using detailed explanations of each disease entity. Learn new subjects in Pulmonary Medicine including Genetics, Ultrasound, and other key topics. Grasp the Key Points in each chapter. Search the full text online at expertconsult.com, along with downloadable images, regular updates, more than 50 videos, case studies, and self-assessment questions. Consult new chapters covering Ultrasound, Innate Immunity, Adaptive Immunity, Deposition and Clearance, Ventilator-Associated Pneumonia. Find critical information easily using the new full-color design that enhances teaching points and highlights challenging concepts. Apply the expertise and fresh ideas of three new editors—Drs. Thomas R. Martin, Talmadge E. King, Jr., and Dean E. Schraufnagel. Review the latest developments in genetics with advice on how the data will affect patient care.

Voltage Gated Sodium Channels

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642415881
Total Pages : 328 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Voltage Gated Sodium Channels by : Peter C. Ruben

Download or read book Voltage Gated Sodium Channels written by Peter C. Ruben and published by Springer Science & Business Media. This book was released on 2014-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.

Acute Pain Management

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Publisher : Cambridge University Press
ISBN 13 : 0521874912
Total Pages : 729 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Acute Pain Management by : Raymond S. Sinatra

Download or read book Acute Pain Management written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2009-04-27 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

Dissertation Abstracts International

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Author :
Publisher :
ISBN 13 :
Total Pages : 660 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 1993 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comparative Biology of the Normal Lung

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Publisher : Academic Press
ISBN 13 : 0124047262
Total Pages : 835 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Comparative Biology of the Normal Lung by : Richard A. Parent

Download or read book Comparative Biology of the Normal Lung written by Richard A. Parent and published by Academic Press. This book was released on 2015-03-13 with total page 835 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comparative Biology of the Normal Lung, Second Edition, offers a rigorous and comprehensive reference for all those involved in pulmonary research. This fully updated work is divided into sections on anatomy and morphology, physiology, biochemistry, and immunological response. It continues to provide a unique comparative perspective on the mammalian lung. This edition includes several new chapters and expanded content, including aging and development of the normal lung, mechanical properties of the lung, genetic polymorphisms, the comparative effect of stress of pulmonary immune function, oxygen signaling in the mammalian lung and much more. By addressing scientific advances and critical issues in lung research, this 2nd edition is a timely and valuable work on comparative data for the interpretation of studies of animal models as compared to the human lung. - Edited and authored by experts in the field to provide an excellent and timely review of cross-species comparisons that will help you interpret and compare data from animal studies to human findings - Incorporates lung anatomy and physiology, cell specific interactions and immunological responses to provide you with a single and unique multidisciplinary source on the comparative biology of the normal lung - Includes new and expanded content on neonatal and aged lungs, developmental processes, cell signaling, antioxidants, airway cells, safety pharmacology and much more - Section IV on Physical and Immunological Defenses has been significantly updated with 9 new chapters and an increased focus on the pulmonary immunological system

Asthma and COPD

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Author :
Publisher : Elsevier
ISBN 13 : 0080920608
Total Pages : 897 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Asthma and COPD by : Peter J. Barnes

Download or read book Asthma and COPD written by Peter J. Barnes and published by Elsevier. This book was released on 2009-03-19 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations

Physiology of Respiration

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Publisher :
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.:/5 (4 download)

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Book Synopsis Physiology of Respiration by : Julius Hiram Comroe

Download or read book Physiology of Respiration written by Julius Hiram Comroe and published by . This book was released on 1974 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Textbook of Neuroanatomy

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Publisher : John Wiley & Sons
ISBN 13 : 1118677358
Total Pages : 544 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis A Textbook of Neuroanatomy by : Maria A. Patestas

Download or read book A Textbook of Neuroanatomy written by Maria A. Patestas and published by John Wiley & Sons. This book was released on 2016-02-17 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Newly revised and updated, A Textbook of Neuroanatomy, Second Edition is a concise text designed to help students easily master the anatomy and basic physiology of the nervous system. Accessible and clear, the book highlights interrelationships between systems, structures, and the rest of the body as the chapters move through the various regions of the brain. Building on the solid foundation of the first edition, A Textbook of Neuroanatomy now includes two new chapters on the brainstem and reflexes, as well as dozens of new micrographs illustrating key structures. Throughout the book the clinical relevance of the material is emphasized through clinical cases, questions, and follow-up discussions in each chapter, motivating students to learn the information. A companion website is also available, featuring study aids and artwork from the book as PowerPoint slides. A Textbook of Neuroanatomy, Second Edition is an invaluable resource for students of general, clinical and behavioral neuroscience and neuroanatomy.

Pharmacology and Therapeutics of Cough

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Publisher : Springer Science & Business Media
ISBN 13 : 3540798420
Total Pages : 380 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Pharmacology and Therapeutics of Cough by : K. Fan Chung

Download or read book Pharmacology and Therapeutics of Cough written by K. Fan Chung and published by Springer Science & Business Media. This book was released on 2008-09-30 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last decade or so has seen remarkable advances in our knowledge of cough. This applies especially to its basic mechanisms: the types of airway sensors, the phar- cological receptors on their membranes, the brainstem organization of the ‘cough centre’, and the involvement of the cerebral cortex in the sensations and the vol- tary control of cough. With the exception of the last of these, nearly all the studies have been on experimental animals rather than humans, for obvious reasons. One group of experimental studies has particular relevance to human patients, and that is the demonstration of the sensitization of cough pathways both in the periphery and in the brainstem. Similar sensitizations have been shown for patients with chronic cough or who have been exposed to pollutants, and it is reasonable to suppose that this is the basis of their cough and that the underlying mechanisms are generally similar in humans and other species. Important advances are also being made in clinical cough research. For the three main causes of clinical cough, asthma, post-nasal drip syndrome, and gast- oesophageal re?ux disease, we are beginning to understand the pathological processes involved. There remains a diagnostically obdurate group of idiopathic chronic coughers, but even for them approaches are being devised to clarify und- lying mechanisms and to establish diagnoses. Perhaps surprisingly, the ?eld in which there has been the least spectacular - vance is the therapy of cough.

Nunn's Applied Respiratory Physiology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1483292053
Total Pages : 681 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Nunn's Applied Respiratory Physiology by : John F Nunn

Download or read book Nunn's Applied Respiratory Physiology written by John F Nunn and published by Elsevier Health Sciences. This book was released on 1993-10-04 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nunn's Applied Respiratory Physiology

The Polyvagal Theory: Neurophysiological Foundations of Emotions, Attachment, Communication, and Self-regulation (Norton Series on Interpersonal Neurobiology)

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Author :
Publisher : W. W. Norton & Company
ISBN 13 : 039370906X
Total Pages : 369 pages
Book Rating : 4.3/5 (937 download)

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Book Synopsis The Polyvagal Theory: Neurophysiological Foundations of Emotions, Attachment, Communication, and Self-regulation (Norton Series on Interpersonal Neurobiology) by : Stephen W. Porges

Download or read book The Polyvagal Theory: Neurophysiological Foundations of Emotions, Attachment, Communication, and Self-regulation (Norton Series on Interpersonal Neurobiology) written by Stephen W. Porges and published by W. W. Norton & Company. This book was released on 2011-04-25 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of groundbreaking research by a leading figure in neuroscience. This book compiles, for the first time, Stephen W. Porges’s decades of research. A leading expert in developmental psychophysiology and developmental behavioral neuroscience, Porges is the mind behind the groundbreaking Polyvagal Theory, which has startling implications for the treatment of anxiety, depression, trauma, and autism. Adopted by clinicians around the world, the Polyvagal Theory has provided exciting new insights into the way our autonomic nervous system unconsciously mediates social engagement, trust, and intimacy.

Air Pollution, the Automobile, and Public Health

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Author :
Publisher : National Academies Press
ISBN 13 : 0309037263
Total Pages : 703 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Air Pollution, the Automobile, and Public Health by : Sponsored by The Health Effects Institute

Download or read book Air Pollution, the Automobile, and Public Health written by Sponsored by The Health Effects Institute and published by National Academies Press. This book was released on 1988-01-01 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The combination of scientific and institutional integrity represented by this book is unusual. It should be a model for future endeavors to help quantify environmental risk as a basis for good decisionmaking." â€"William D. Ruckelshaus, from the foreword. This volume, prepared under the auspices of the Health Effects Institute, an independent research organization created and funded jointly by the Environmental Protection Agency and the automobile industry, brings together experts on atmospheric exposure and on the biological effects of toxic substances to examine what is knownâ€"and not knownâ€"about the human health risks of automotive emissions.

The Temporal Progression of Pulmonary Function and Subjective Symptom Responses to Ozone Exposure in Exercising Males and Females

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Publisher :
ISBN 13 :
Total Pages : 198 pages
Book Rating : 4.:/5 (33 download)

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Book Synopsis The Temporal Progression of Pulmonary Function and Subjective Symptom Responses to Ozone Exposure in Exercising Males and Females by : Kimberly Lynn Filler

Download or read book The Temporal Progression of Pulmonary Function and Subjective Symptom Responses to Ozone Exposure in Exercising Males and Females written by Kimberly Lynn Filler and published by . This book was released on 1987 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: