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Author : Fu Wang
Publisher : Frontiers Media SA
ISBN 13 : 283252866X
Total Pages : 481 pages
Book Rating : 4.8/5 (325 download)
Download or read book The role of immunophenotype in tumor immunotherapy response written by Fu Wang and published by Frontiers Media SA. This book was released on 2023-07-03 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gábor J. Szebeni
Publisher : MDPI
ISBN 13 : 3039434667
Total Pages : 170 pages
Book Rating : 4.0/5 (394 download)
Download or read book Immunophenotyping in Autoimmune Diseases and Cancer written by Gábor J. Szebeni and published by MDPI. This book was released on 2020-12-02 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cooperation of highly specialized cell types maintains the homeostasis of multicellular organisms. The disturbance of that harmony contributes to the development of several diseases. Most of the cellular functions are executed by proteins, so it is essential to investigate biological processes at the protein level. Antibodies, complex biomolecules with high specificity, are used to recognize our protein of interest in a process known as “immunophenotyping”. One of the routinely used methods to study cellular proteins is flow cytometry, which detects cell surface or intracellular proteins at single-cell resolution. The other most frequent technique is the traditional immunohistochemical investigation of microscopic sections of human tissues. We called authors to publish their latest data studying cancer or autoimmune diseases by immunophenotyping.
Author : Mikhail V. Kiselevsky
Publisher : Springer Science & Business Media
ISBN 13 : 1402069316
Total Pages : 166 pages
Book Rating : 4.4/5 (2 download)
Download or read book Atlas Effectors of Anti-Tumor Immunity written by Mikhail V. Kiselevsky and published by Springer Science & Business Media. This book was released on 2008-03-30 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Atlas is a unique scientific publication. It includes major issues of up-to-date information about immunophenotype, morphology and the function of the main effectors of anti-tumor immunity set down in a well presented format. The Atlas comprises a large number of illustrations presenting schemes and original micrographs demonstrating morphological features and ultrastructure of immunocompetent cells at various stages of differentiation. A special section of the Atlas describes cellular tumor microenvironment and micro-anatomy of carcinomas. Several parts include data about killer cells and T-regulatory lymphocytes.
Author : Andreas Radbruch
Publisher : Springer Science & Business Media
ISBN 13 : 3662041294
Total Pages : 365 pages
Book Rating : 4.6/5 (62 download)
Download or read book Flow Cytometry and Cell Sorting written by Andreas Radbruch and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analysis and sorting of large numbers of cells with a fluorescence-activated cell sorter (FACS) was first achieved some 30 years ago. Since then, this technology has been rapidly developed and is used today in many laboratories. A Springer Lab Manual Review of the First Edition: "This is a most useful volume which will be a welcome addition for personal use and also for laboratories in a wide range of disciplines. Highly recommended." CYTOBIOS
Author : Anna Porwit
Publisher : Cambridge University Press
ISBN 13 : 1108548830
Total Pages : 248 pages
Book Rating : 4.1/5 (85 download)
Download or read book Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies written by Anna Porwit and published by Cambridge University Press. This book was released on 2018-01-25 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.
Author : Stephen J. Withrow
Publisher : Elsevier Health Sciences
ISBN 13 : 1437723624
Total Pages : 775 pages
Book Rating : 4.4/5 (377 download)
Download or read book Withrow and MacEwen's Small Animal Clinical Oncology written by Stephen J. Withrow and published by Elsevier Health Sciences. This book was released on 2012-11-13 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a unique focus on the most effective interventional techniques, Withrow & MacEwen's Small Animal Clinical Oncology, 5th Edition tells the full story of cancer in dogs and cats - what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice. Nearly 500 color photographs, diagrams, x-rays, and gross views depict the clinical manifestations of various cancers. This edition covers the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. With contributions from 65 veterinary oncology experts, this authoritative reference is a must-have for current, evidence-based therapeutic strategies on canine and feline oncology. "I really love this book. If you are interested in veterinary oncology, have a flick through this book online or at a conference when you get the chance. I hope that you agree with me that this is the definitive oncology reference source for the early 21st century and that you feel compelled to buy it. Your patients will thank you for it." Reviewed by: Gerry Polton MA VetMB MSc(Clin Onc) DipECVIM-CA(Onc) MRCVS, UK Date: July 2014 Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist. A consistent format for chapters on body system tumors includes coverage of incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies. A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients. Nearly 500 color images provide accurate depictions of specific diseases and procedures. Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment. Expert contributors provide in-depth coverage of the most current information in his or her respective specialty in veterinary oncology. Chemotherapy protocols are included when case studies prove clinical efficacy. Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet's pain and nutritional complications as well as the pet owner's grief when treatment is not successful. Thoroughly UPDATED chapters cover the most recent changes in the clinical management of melanoma, mast cell tumors, tumors of the skeletal system, tumors of the endocrine system, tumors of the mammary gland, urinary cancers, nervous system cancers, lymphoma, and histiocytic diseases. NEW Clinical Trials and Developmental Therapeutics chapter discusses the various phases of clinical trials as well as current challenges and opportunities in oncology drug development. NEW! A focus on the best recommended treatment options highlights therapeutic strategies that have been vetted by veterinary oncology experts. NEW co-author Dr. Rodney L. Page adds his valuable perspective, expertise, and research experience.
Author : Endi Wang
Publisher : Springer Nature
ISBN 13 : 3030321894
Total Pages : 750 pages
Book Rating : 4.0/5 (33 download)
Download or read book Practical Lymph Node and Bone Marrow Pathology written by Endi Wang and published by Springer Nature. This book was released on 2020-03-28 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a step-by-step and practically applicable approach for the accurate and clinically relevant diagnosis of lymph node (LN) and bone marrow (BM) biopsies. Clinicians expect pathological guidance not only with accurate diagnosis, but also about disease progression, minimal residual disease, disease susceptibility to a particular therapy, effects of prior therapy on prognosis and subsequent therapy etc. This book provides brief but to the point guidance about the prognostic and therapeutic implications of key ancillary studies so that the pathologist is comfortable to answer clinician’s questions over the entire arc of manifestations and management of the disease. The text follows the WHO (2016) classification in essence but the material is organized in a fashion most useful to a practicing surgical pathologist. This is achieved by focusing on the morphological findings as the starting point. Using this morphological “backbone” and several frequently asked questions (FAQs) the reader is guided to a rational list of differential diagnoses leading to a definitive diagnosis. The contents of each chapter are carefully selected so that the practically important and directly applicable information is available in an easy-to-find and easy-to-grasp format. Practical Lymph Node and Bone Marrow Pathology serves as a practical introduction and handbook for pathology trainees and hematopathology fellows and will remain a useful reference to practicing pathologists when they are signing out lymph nodes or bone marrow specimens.
Author : Susan Costantini Alfredo Budillon
Publisher : MDPI
ISBN 13 : 3039439774
Total Pages : 294 pages
Book Rating : 4.0/5 (394 download)
Download or read book New Prognostic and Predictive Markers in Cancer Progression written by Susan Costantini Alfredo Budillon and published by MDPI. This book was released on 2021-02-12 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers are of critical medical importance for oncologists, allowing them to predict and detect disease and to determine the best course of action for cancer patient care. Prognostic markers are used to evaluate a patient’s outcome and cancer recurrence probability after initial interventions such as surgery or drug treatments and, hence, to select follow-up and further treatment strategies. On the other hand, predictive markers are increasingly being used to evaluate the probability of benefit from clinical intervention(s), driving personalized medicine. Evolving technologies and the increasing availability of “multiomics” data are leading to the selection of numerous potential biomarkers, based on DNA, RNA, miRNA, protein, and metabolic alterations within cancer cells or tumor microenvironment, that may be combined with clinical and pathological data to greatly improve the prediction of both cancer progression and therapeutic treatment responses. However, in recent years, few biomarkers have progressed from discovery to become validated tools to be used in clinical practice. This Special Issue comprises eight review articles and five original studies on novel potential prognostic and predictive markers for different cancer types.
Author : Mourad Aribi
Publisher : BoD – Books on Demand
ISBN 13 : 178985430X
Total Pages : 163 pages
Book Rating : 4.7/5 (898 download)
Download or read book Normal and Malignant B-Cell written by Mourad Aribi and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Normal and Malignant B-Cell is a collection of harmonious chapters contributed by different authors. This book sets out to describe the B-cell during different stages of ontogeny and the molecular mechanisms of its antigen receptor diversity. It also discusses the main clinical and etiopathogenic aspects when it is transformed into a malignant cell. The book will be interesting and useful for clinicians, biologists, researchers, teachers, and graduate students of both doctoral and master's degrees in the field of immunology.
Author : Nima Rezaei
Publisher : Academic Press
ISBN 13 : 0128140402
Total Pages : 198 pages
Book Rating : 4.1/5 (281 download)
Download or read book Vaccines for Cancer Immunotherapy written by Nima Rezaei and published by Academic Press. This book was released on 2018-10-17 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic cancer vaccines represent a type of active cancer immunotherapy. Clinicians, scientists, and researchers working on cancer treatment require evidence-based and up-to-date resources relating to therapeutic cancer vaccines. Vaccines for Cancer Immunotherapy provides a reference for cancer treatment for clinicians and presents a well-organized resource for determining high-potential research areas. The book considers that this promising modality can be made more feasible as a treatment for cancer. Chapters cover cancer immunology, general approaches to cancer immunotherapy, vaccines, tumor antigens, the strategy of allogeneic and autologous cancer vaccines, personalized vaccines, whole-tumor antigen vaccines, protein and peptide vaccines, dendritic cell vaccines, genetic vaccines, candidate cancers for vaccination, obstacles to developing therapeutic cancer vaccines, combination therapy, future perspectives and concluding remarks on therapeutic cancer vaccines. Introduces the feasible immunotherapeutic vaccines for patients with different types of cancer Presents the status of past and current vaccines for cancer treatment Considers advantages and disadvantages of different therapeutic cancer vaccines Looks at the combination of vaccines and other modalities, including immunotherapeutic and conventional methods Analyzes obstacles to development of therapeutic cancer vaccines Gives a view on future perspectives in the application of therapeutic cancer vaccines
Author : Zhouxiao Li
Publisher : Frontiers Media SA
ISBN 13 : 2832537332
Total Pages : 693 pages
Book Rating : 4.8/5 (325 download)
Download or read book The role of the tumor microenvironment (TME) and relevant novel biomarkers in oncogenesis written by Zhouxiao Li and published by Frontiers Media SA. This book was released on 2024-01-15 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ali S. Faqi
Publisher : Elsevier
ISBN 13 : 0323984622
Total Pages : 1074 pages
Book Rating : 4.3/5 (239 download)
Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Elsevier. This book was released on 2024-02-11 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology
Author : Yongwen Luo
Publisher : Frontiers Media SA
ISBN 13 : 2889766292
Total Pages : 250 pages
Book Rating : 4.8/5 (897 download)
Download or read book Molecular Biomarkers and Imaging Markers in the Prediction, Diagnosis, and Prognosis of Bladder Cancer written by Yongwen Luo and published by Frontiers Media SA. This book was released on 2022-07-27 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ajay Vora
Publisher : Springer
ISBN 13 : 3319397087
Total Pages : 342 pages
Book Rating : 4.3/5 (193 download)
Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Author : Ana Carolina Monteiro
Publisher : Frontiers Media SA
ISBN 13 : 2832516203
Total Pages : 181 pages
Book Rating : 4.8/5 (325 download)
Download or read book Tumor microenvironment immunophenotypes and disease progression written by Ana Carolina Monteiro and published by Frontiers Media SA. This book was released on 2023-03-02 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lan Zhao
Publisher : Frontiers Media SA
ISBN 13 : 283251748X
Total Pages : 416 pages
Book Rating : 4.8/5 (325 download)
Download or read book Genomics of immunoregulation and inflammatory responses in the tumor microenvironment written by Lan Zhao and published by Frontiers Media SA. This book was released on 2023-03-15 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Valérie Dutoit
Publisher : Frontiers Media SA
ISBN 13 : 2889741915
Total Pages : 212 pages
Book Rating : 4.8/5 (897 download)
Download or read book Impact of the Glioma Microenvironment on Antitumor Immunity written by Valérie Dutoit and published by Frontiers Media SA. This book was released on 2022-01-31 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
