The Primordial Vrm System And The Evolution Of Vertebrate Immunity

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The Primordial VRM System and the Evolution of Vertebrate Immunity

Author : John Stewart
Publisher : R. G. Landes
ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Primordial VRM System and the Evolution of Vertebrate Immunity by : John Stewart

Download or read book The Primordial VRM System and the Evolution of Vertebrate Immunity written by John Stewart and published by R. G. Landes. This book was released on 1994 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the evolutionary origin of immunoglobulins and T-cell receptors. The complex interactions between B and T cells in response to external antigens are the major focus of contemporary immunology. This book argues that these interactions may be relatively late evolutionary developments, due to the redeployment of a system invented for other reasons. In other words immunoglobulins did not arise in evolution to fight infection. The author theorizes that the system of variable region moleculars (VRM) arose at the time of the first vertebrates by an endogenous, self-organizing process. This primordial VRM system instituted a molecular ecology, a function so vital that from then on no vertebrate has been able to do without it.

Immunity

Author : Alfred I. Tauber
Publisher : Oxford University Press
ISBN 13 : 0190651245
Total Pages : 329 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Immunity by : Alfred I. Tauber

Download or read book Immunity written by Alfred I. Tauber and published by Oxford University Press. This book was released on 2017 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine generated contents note: -- Preface -- Acknowledgements -- Introduction -- Chapter 1: A History of the Immune Self -- Chapter 2: Whither Immune Identity? -- Chapter 3: Individuality Revised -- Chapter 4: Immune Cognition -- Chapter 5: Eco-immunology -- Chapter 6: A New Biology? -- Epilogue -- Endnotes -- References. 650

The Ecology and Evolution of Inducible Defenses

Author : Ralph Tollrian
Publisher : Princeton University Press
ISBN 13 : 0691228191
Total Pages : 395 pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis The Ecology and Evolution of Inducible Defenses by : Ralph Tollrian

Download or read book The Ecology and Evolution of Inducible Defenses written by Ralph Tollrian and published by Princeton University Press. This book was released on 2021-04-13 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inducible defenses--those often dramatic phenotypic shifts in prey activated by biological agents ranging from predators to pathogens--are widespread in the natural world. Yet research on the inducible defenses used by vertebrates, invertebrates, and plants in terrestrial, marine, and freshwater habitats has largely developed along independent lines. Ralph Tollrian and Drew Harvell seek to change that here. By bringing together leading researchers from all fields to review common themes and explore emerging ideas, this book represents the most current and comprehensive survey of knowledge about the ecology and evolution of inducible defenses. Contributors examine organisms as different as unicellular algae and higher vertebrates, and consider defenses ranging from immune systems to protective changes in morphology, behavior, chemistry, and life history. The authors of the review chapters, case studies, and theoretical studies pinpoint unifying factors favoring the evolution of inducible defenses. Throughout, the volume emphasizes a multidisciplinary approach, integrating applied and theoretical ecology, evolution, genetics, and chemistry. In addition, Harvell and Tollrian provide an introduction and a conclusion that review the current state of knowledge in the field and identify areas for future research. The contributors, in addition to the editors, are May Berenbaum, Arthur Zangerl, Johannes Järemo, Juha Tuomi, Patric Nilsson, Anurag Agrawal, Richard Karban, Marcel Dicke, Ellen Van Donk, Miquel Lürling, Winfried Lampert, Simon Frost, John Gilbert, Hans-Werner Kuhlmann, Jürgen Kusch, Klaus Heckmann, Luc De Meester, Piotr Dawidowicz, Erik van Gool, Carsten Loose, Stanley Dodson, Christer Brönmark, Lars Pettersson, Anders Nilsson, Bradley Anholt, Earl Werner, Curtis Lively, Frederick Adler, Daniel Grünbaum, and Wilfried Gabriel.

Theoretical and Experimental Insights into Immunology

Author : Alan S. Perelson
Publisher : Springer Science & Business Media
ISBN 13 : 3642769772
Total Pages : 485 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Theoretical and Experimental Insights into Immunology by : Alan S. Perelson

Download or read book Theoretical and Experimental Insights into Immunology written by Alan S. Perelson and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology is largely a science of observation and experimentation, and these approaches have lead to great increases in our knowledge of the genes, molecules and cells of the immune system. This book is an up-to-date discussion of the current state of modelling and theoretical work in immunology, of the impact of theory on experiment, and of future directions for theoretical research. Among the topics discussed are the function and evolution of the immune system, computer modelling of the humoral immune response and of idiotypic networks and idiotypic mimicry, T-cell memory, cryptic peptides, new views and models of AIDS and autoimmunity, and the shaping of the immune repertoire by early presented antigens and self immunoglobulin.

Darwin's Black Box

Author : Michael J. Behe
Publisher : Simon and Schuster
ISBN 13 : 0743214854
Total Pages : 320 pages
Book Rating : 4.7/5 (432 download)

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Book Synopsis Darwin's Black Box by : Michael J. Behe

Download or read book Darwin's Black Box written by Michael J. Behe and published by Simon and Schuster. This book was released on 2001-04-04 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The groundbreaking, "seminal work" (Time) on intelligent design that dares to ask, was Darwin wrong? In 1996, Darwin's Black Box helped to launch the intelligent design movement: the argument that nature exhibits evidence of design, beyond Darwinian randomness. It sparked a national debate on evolution, which continues to intensify across the country. From one end of the spectrum to the other, Darwin's Black Box has established itself as the key intelligent design text—the one argument that must be addressed in order to determine whether Darwinian evolution is sufficient to explain life as we know it. In a major new Afterword for this edition, Behe explains that the complexity discovered by microbiologists has dramatically increased since the book was first published. That complexity is a continuing challenge to Darwinism, and evolutionists have had no success at explaining it. Darwin's Black Box is more important today than ever.

Artificial Immune Systems

Author : Christian Jacob
Publisher : Springer Science & Business Media
ISBN 13 : 3540281754
Total Pages : 511 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Artificial Immune Systems by : Christian Jacob

Download or read book Artificial Immune Systems written by Christian Jacob and published by Springer Science & Business Media. This book was released on 2005-08-04 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 4th International Conference on Artificial Immune Systems, ICARIS 2005, held in Banff, Alberta, Canada, in August 2005. The 37 revised full papers presented were carefully reviewed and selected from 68 submissions. The papers are organized in topical sections on conceptual, formal, and theoretical frameworks, immunoinformatics, theoretical and experimental studies on artificial immune systems, and applications of artificial immune systems.

Signal Transduction and Bacterial Virulence

Author : Rino Rappuoli
Publisher : Springer Science & Business Media
ISBN 13 : 3662224062
Total Pages : 178 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis Signal Transduction and Bacterial Virulence by : Rino Rappuoli

Download or read book Signal Transduction and Bacterial Virulence written by Rino Rappuoli and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to survive, bacteria must constantly monitor their structure and physiology. Adaptive behaviours are established by using environmental sensors and response regulators. These communication modules regulate a wide variety of signals including host detection and invasion, cell cycle, metabolite utilization, starvation and many others. The purpose of this volume is to give an overview of the various systems and to introduce recent advances in understanding selected systems of pathogenic bacteria.

Advances in Artificial Life

Author : Wolfgang Banzhaf
Publisher : Springer
ISBN 13 : 354039432X
Total Pages : 922 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Advances in Artificial Life by : Wolfgang Banzhaf

Download or read book Advances in Artificial Life written by Wolfgang Banzhaf and published by Springer. This book was released on 2011-03-31 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 7th European Conference on Artificial Life, ECAL 2003, held in Dortmund, Germany in September 2003. The 96 revised full papers presented were carefully reviewed and selected from more than 140 submissions. The papers are organized in topical sections on artificial chemistries, self-organization, and self-replication; artificial societies; cellular and neural systems; evolution and development; evolutionary and adaptive dynamics; languages and communication; methodologies and applications; and robotics and autonomous agents.

The Philosophy of Science: A-M

Author : Sahotra Sarkar
Publisher : Taylor & Francis
ISBN 13 : 9780415977098
Total Pages : 536 pages
Book Rating : 4.9/5 (77 download)

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Book Synopsis The Philosophy of Science: A-M by : Sahotra Sarkar

Download or read book The Philosophy of Science: A-M written by Sahotra Sarkar and published by Taylor & Francis. This book was released on 2006 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first in-depth reference to the field that combines scientific knowledge with philosophical inquiry, this encyclopedia brings together a team of leading scholars to provide nearly 150 entries on the essential concepts in the philosophy of science. The areas covered include biology, chemistry, epistemology and metaphysics, physics, psychology and mind, the social sciences, and key figures in the combined studies of science and philosophy. (Midwest).

Estrogen and Breast Cancer

Author : W. R. Miller
Publisher : Landes Bioscience
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Estrogen and Breast Cancer by : W. R. Miller

Download or read book Estrogen and Breast Cancer written by W. R. Miller and published by Landes Bioscience. This book was released on 1996 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Human T-Cell Receptor Repertoire and Transplantation

Author : Peter van den Elsen
Publisher : Springer Science & Business Media
ISBN 13 : 3662224941
Total Pages : 217 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis The Human T-Cell Receptor Repertoire and Transplantation by : Peter van den Elsen

Download or read book The Human T-Cell Receptor Repertoire and Transplantation written by Peter van den Elsen and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: these analyses it became clear that the MHC class I molecule com prised a distinct groove on the external side of the molecule. The sides of the groove are formed by the a-helical structures of the a and a 1 2 domains and a floor which is formed by 8 anti-parallel 13 strands. The various polymorphic residues, as determined from DNA sequence analysis, are localized within these a-helices and 13-plated sheets within the groove. More importantly, these analyses also revealed the presence of elec tron-dense material in the groove. This material was subsequently iden 568 10 tified as a linear peptide of 8-10 amino acids long. • •- High resolu tion crystallographic analyses of the class I MHC structure have revealed the existence of so-called pockets within the grooves of the MHC class I molecules. These pockets designated A-F, exhibited allele-specificity and are directly involved in the binding of the peptide, primarily through interaction with the dominant anchor residues as found in MHC class I associated pep tides. 6,7,9,11 The class II MHC antigens consist on the cell surface of a 34 kD a chain non-covalently associated with a 28 kD 13 chain. With the excep tion of the DR a-chain, all other MHC class II a and 13 chains are poly morphic.

"Glucokinase": Its Regulation and Role in Liver Metabolism

Author : Maria L. Cardenas
Publisher : Springer
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis "Glucokinase": Its Regulation and Role in Liver Metabolism by : Maria L. Cardenas

Download or read book "Glucokinase": Its Regulation and Role in Liver Metabolism written by Maria L. Cardenas and published by Springer. This book was released on 1995-07 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the hexokinase isoenzyme responsible for glucose phosphorylation in hepatocytes, commonly known as glucokinase. Its importance derives from the fact that glucose uptake by the liver is an essential physiological process, crucial for glucose homeostasis. This volume is the first to try to integrate all of the important information about hexokinase D into a single book, and thereby allows a reader concerned with any particular aspect of the enzyme to place it in a more general context.

Intracellular Protein Transport and Membrane Biogenesis

Author : Keith Verner
Publisher :
ISBN 13 :
Total Pages : 198 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Intracellular Protein Transport and Membrane Biogenesis by : Keith Verner

Download or read book Intracellular Protein Transport and Membrane Biogenesis written by Keith Verner and published by . This book was released on 1995 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about membrane biogenesis and protein transport across biological membranes. Both prokaryotic and eukaryotic membrane transport systems are considered. The characteristics of targeting signals and membrane receptors on various intracellular organelles are described. Protein targeting to the endoplasmic reticulum and secretion via vesicular transport are discussed. In addition, recent developments in protein targeting and membrane transport to mitochondria, chloroplasts, peroxisomes and the nucleus are described. An introductory chapter on biological membranes is included as a review while a chapter on the transport of lipids to intracellular membranes precedes discussions on protein transport and membrane translocation.

Adult T Cell Leukemia and Related Diseases

Author : Takashi Uchiyama
Publisher : Springer
ISBN 13 :
Total Pages : 158 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Adult T Cell Leukemia and Related Diseases by : Takashi Uchiyama

Download or read book Adult T Cell Leukemia and Related Diseases written by Takashi Uchiyama and published by Springer. This book was released on 1995 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews research in adult T cell leukemia (ATL), one of the central disorders related to infections caused by the retrovirus human T lymphotrophic virus (HTLV-1), for researchers and clinicians. Describes clinical features of ATL and other related diseases and biological properties of cells, explains the IL-2/IL-2 receptor system in ATL and redox regulation and ATL-derived factor, and compares the relationship between AIDS and HIV to ATL and HTLV-1. Includes bandw diagrams and photos. Annotation copyright by Book News, Inc., Portland, OR

DNA and Nucleoprotein Structure in Vivo

Author : H. P. Saluz
Publisher : Springer
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis DNA and Nucleoprotein Structure in Vivo by : H. P. Saluz

Download or read book DNA and Nucleoprotein Structure in Vivo written by H. P. Saluz and published by Springer. This book was released on 1995 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the structural aspects of nucleic acids in vivo and interactions between proteins and DNA in living cells. It provides an overview of the techniques involved by which the study of native genomes has been greatly facilitated. It also gives a description of the mode of action of many different DNA modifying agents which can be used for such studies. Furthermore, it describes the limitations of the currently existing techniques, includes some relevant applications and shows potential future developments. This book is recommended for anyone interested in the qualitative and quantitative study of native genomes.

Glucocorticoid Receptor Structure and Leukemic Cell Responses

Author : Bahiru Gametchu
Publisher : Springer
ISBN 13 :
Total Pages : 206 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Glucocorticoid Receptor Structure and Leukemic Cell Responses by : Bahiru Gametchu

Download or read book Glucocorticoid Receptor Structure and Leukemic Cell Responses written by Bahiru Gametchu and published by Springer. This book was released on 1995 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Signal Transduction Mechanisms in Cancer

Author : Hans Grunicke
Publisher : Springer
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.4/5 (324 download)

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Book Synopsis Signal Transduction Mechanisms in Cancer by : Hans Grunicke

Download or read book Signal Transduction Mechanisms in Cancer written by Hans Grunicke and published by Springer. This book was released on 1995-10 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elucidation of the function of oncogenes in tumor suppressor genes revealed that malignant growth can be understood as a malfunction of information transfer systems employed for transmission of stimulatory or inhibitory signals for growth control. This book presents a comprehensive view reflecting our present knowledge of the whole area of molecular biology and biochemistry of positive and negative growth control and the implication of proto-oncogenes and tumor suppressor genes in these mechanisms. On the basis of this information, new strategies for the development of anti-tumor agents are also discussed.