The Plasma Proteins V2

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Publisher : Elsevier
ISBN 13 : 0323146821
Total Pages : 535 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Plasma Proteins V2 by : Frank Putnam

Download or read book The Plasma Proteins V2 written by Frank Putnam and published by Elsevier. This book was released on 2012-12-02 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Plasma Proteins, Volume II: Biosynthesis, Metabolism, Alternations in Disease is a 10-chapter text that explores the physiological role and metabolic interrelationships of the human plasma proteins in the normal state and in disease. The first two chapters cover the physical properties, chemical composition, function, methods of analysis of human serum lipoproteins and plasma enzymes. The subsequent chapter considers the normal levels of hormones in plasma or serum and their distribution in the plasma protein fractions. These topics are followed by discussions on the blood coagulation system, the serum proteins in the animal kingdom at maturity and during embryonic development, and the biosynthesis of plasma proteins. The remaining chapters examine the qualitative abnormalities in various plasma proteins. These chapters also discuss the modification in plasma protein synthesis induced by genetic variation. Such alterations are described for albumin, ceruloplasmin, haptoglobin, iron-binding globulin, fibrinogen, antihemophilic globulin, and other blood clotting factors, as well as ?-globulin. Biochemists, physiologists, and medical researchers will find this book invaluable.

The Plasma Proteins

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Publisher :
ISBN 13 :
Total Pages : 444 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis The Plasma Proteins by : Frank W. Putnam

Download or read book The Plasma Proteins written by Frank W. Putnam and published by . This book was released on 1960 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of the Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Plasma Proteins

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Publisher : Academic Press
ISBN 13 : 148325867X
Total Pages : 437 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Plasma Proteins by : Frank W Putnam

Download or read book The Plasma Proteins written by Frank W Putnam and published by Academic Press. This book was released on 2014-05-12 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Plasma Proteins, Volume I: Isolation, Characterization, and Function focuses on the reactions, properties, characteristics, and transformations of plasma proteins. The selection first offers information on the fractionation and isolation of purified components by precipitation methods and electrophoretic and ultracentrifugal analysis of normal human serum. Discussions focus on correlation of electrophoretic and ultracentrifugal results, electrophoretic analytical methodology and results, parameters influencing protein solubility, and techniques for the separation of proteins by precipitation methods. The text then ponders on the chromatography of plasma proteins and chemical composition and molecular parameters of purified plasma proteins. The manuscript elaborates on plasma albumin and macroglobulins and high molecular weight antibodies. Topics include immunological properties, physical and chemical properties of normal and pathological macroglobulins, purity, homogeneity, and variability, denaturation behavior, and sulfhydryl groups, mercaptalbumin, and the mercury dimer. The book then examines glycoproteins and metal-binding plasma proteins and cation transport. The selection is a highly recommended reference for biochemists and clinicians interested in plasma proteins.

The Plasma Proteins V4

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Publisher : Elsevier
ISBN 13 : 0323161731
Total Pages : 439 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Plasma Proteins V4 by : Frank Putnam

Download or read book The Plasma Proteins V4 written by Frank Putnam and published by Elsevier. This book was released on 2012-12-02 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Plasma Proteins: Structure, Function, and Genetic Control is a systematic account of the structure, function, and genetic control of plasma proteins. Advances in the characterization and posttranslational modification of plasma proteins are discussed, along with the structure of a variety of plasma proteins such as serum albumin, glycoproteins, and serum lipoproteins, and immunoglobulins. Comprised of six chapters, this volume begins with a review of progress in plasma proteins, focusing on their three-dimensional structure, characterization, and microheterogeneity as well as genetic polymorphism and chromosomal mapping. The second chapter gives a comprehensive summary of the structure of nearly 100 proteins, from serum albumin and glycoproteins to serum lipoproteins, thyroxine-binding proteins, and immunoglobulins. The reader is then introduced to human plasma proteins of unknown function, together with high-resolution two-dimensional electrophoretic mapping. The remaining chapters explore developments in the structural study of carbon hydrates; synthesis, structure, and function of the oligosaccharides of plasma glycoproteins; and the evolution of the vertebrate plasma proteins. This monograph will be of interest to molecular biologists and biochemists.

Clinical Aspects of The Plasma Proteins

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Publisher : Springer Science & Business Media
ISBN 13 : 3662062674
Total Pages : 475 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Clinical Aspects of The Plasma Proteins by : Tadashi Kawai

Download or read book Clinical Aspects of The Plasma Proteins written by Tadashi Kawai and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was the year of 1969 when this monograph was originally published in Japanese by Professor TADASHI KAWAI, titled as "The Plasma Proteins, Their Fundamental and Clinical Aspects." After I read through the Japanese edition, I was impressed by its rather complete coverage of the subjects and their detailed descriptions. I have felt that this excellent monograph should be distributed not only among our Japanese scien tists but also among many other colleagues throughout the world. I am happy, the refore, to know that the English edition of his monograph, partly revised, is ready to be published at this time. Professor KAWAI received his postgraduate medical training in U.S.A. for seven years, and was certified by the American Board of Pathology in both Anatomical and Clinical Pathology in Fall, 1962. Thus, I believe, he is the most suitable fellow for publishing the English edition of this kind.

Human Blood Plasma Proteins

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Publisher : John Wiley & Sons
ISBN 13 : 9780470724361
Total Pages : 538 pages
Book Rating : 4.7/5 (243 download)

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Book Synopsis Human Blood Plasma Proteins by : Johann Schaller

Download or read book Human Blood Plasma Proteins written by Johann Schaller and published by John Wiley & Sons. This book was released on 2008-05-23 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include: introduction to blood components and blood plasma proteins blood plasma protein domains, motifs and repeats blood plasma protein families and posttranslational modifications blood coagulation and fibrinolysis the complement system the immune system enzymes inhibitors lipoproteins hormones cytokines and growth factors transport and storage The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure. Attractively presented in full colour, Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.

Production of Plasma Proteins for Therapeutic Use

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Publisher : John Wiley & Sons
ISBN 13 : 0470924314
Total Pages : 518 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Production of Plasma Proteins for Therapeutic Use by : Joseph Bertolini

Download or read book Production of Plasma Proteins for Therapeutic Use written by Joseph Bertolini and published by John Wiley & Sons. This book was released on 2012-12-26 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production of plasma derivatives, the book describes the biology, development, research, manufacture, and clinical indications of essentially all plasma proteins with established clinical use or therapeutic potential. Production of Plasma Proteins for Therapeutic Use covers the key aspects of the plasma fractionation industry in five sections: Section 1: Introduction to Plasma Fractionation initially describes the history of transfusion and then covers the emergence of plasma collection and fractionation from its earliest days to the present time, with the commercial and not-for-profit sectors developing into a multi-billion dollar industry. Section 2: Plasma Proteins for Therapeutic Use contains 24 chapters dedicated to specific plasma proteins, including coagulation factors, albumin, immunoglobulin, and a comprehensive range of other plasma-derived proteins with therapeutic indications. Each chapter discusses the physiology, biochemistry, mechanism of action, and manufacture of each plasma protein including viral safety issues and clinical uses. Section 3: Pathogen Safety of Plasma Products examines issues and procedures for enhancing viral safety and reducing the risk of transmissible spongiform encephalopathy transmission. Section 4: The Pharmaceutical Environment Applied to Plasma Fractionation details the requirements and activities associated with plasma collection, quality assurance, compliance with regulatory requirements, provision of medical affairs support, and the manufacture of plasma products. Section 5: The Market for Plasma Products and the Economics of Fractionation reviews the commercial environment and economics of the plasma fractionation industry including future trends, highlighting regions such as Asia, which have the potential to exert a major influence on the plasma fractionation industry in the twenty-first century.

Pathophysiology of Plasma Protein Metabolism

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Publisher : Springer Science & Business Media
ISBN 13 : 1461327938
Total Pages : 409 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Pathophysiology of Plasma Protein Metabolism by : Giulian Mariant

Download or read book Pathophysiology of Plasma Protein Metabolism written by Giulian Mariant and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a factual account of the proceedings of an international symposium on the pathophysiology of plasma protein metabolism, which was organised in October 1982 by the Plasmaprotein and Immunology Division of the C.N.R. Institute of Clinical Physiology at the University of Pisa (Italy). Several of the contributors are former members of the International Study Group on Plasma Protein Metabolism, the last meeting of which was held in Turin (Italy) in 1974, under the auspices of the scientific organisation of the same institute. The symposium took the form of a series of lectures, with the main objective of providing a positive contribution to the state of the art of several topics related to the kinetic and pathophysiological factors regulating the synthesis, distribution and degradation of plasma proteins. The first four chapters form a group, each one considering a special aspect of the kinetics of turnover and distribution of plasma proteins in general; particular attention is paid to the recent advances in the field of kinetic modelling, the choice of the best models and the optimisation of the experimental designs. The next seven chapters consider the regulation of synthesis, distribution and catab olism of various classes of plasma proteins including albumin, immunoglobulins, complement fractions and acute-phase proteins. The remaining chapters deal with metabolic studies of various plasma proteins (including tumour markers, coagUlation proteins and lipoproteins) in different disease states, such as malig nancies, coagulative disorders, malnutrition and the extensive group of athero sclerotic cardiovascular diseases.

Plasma Protein Metabolism

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Publisher : Elsevier
ISBN 13 : 0323145183
Total Pages : 585 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Plasma Protein Metabolism by : Marcus Rothschild

Download or read book Plasma Protein Metabolism written by Marcus Rothschild and published by Elsevier. This book was released on 2012-12-02 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma Protein Metabolism: Regulation of Synthesis, Distribution, and Degradation covers the concepts concerning the physiological and pathophysiological factors regulating the distribution, degradation, and synthesis of plasma proteins. This book is organized into nine parts encompassing 32 chapters. The first parts present the assumptions and methodology involved in the various in vivo and in vitro techniques that provide insights to protein metabolism. The next parts describe the techniques of protein isolation, characterization, labeling, and mathematical analysis of the data, as well as the methods for directly quantitating protein synthetic rates in nonsteady state conditions. Other parts are devoted to the factors involved in regulating the serum levels of albumin, acute phase reactants, immunoglobulins, clotting factors, complement and hormone-binding proteins. The controlling factors include such general and specific physiological regulators of protein synthesis and catabolism as levels of specific serum proteins, hormonal regulators, variations of temperature and oncotic pressure, antigenic stimulation, and nutritional factors. The remaining parts analyze the pathophysiological factors including disorders of protein synthesis, distribution, exogenous catabolism, and external loss and stress that produce abnormal levels of serum proteins. This book is intended primarily intended to protein chemists and researchers.

Hepatic Plasma Proteins

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Publisher : Elsevier
ISBN 13 : 1483216500
Total Pages : 298 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Hepatic Plasma Proteins by : Barbara H. Bowman

Download or read book Hepatic Plasma Proteins written by Barbara H. Bowman and published by Elsevier. This book was released on 2014-05-10 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities; the acute-phase reactants; and the variety of human plasma proteinase inhibitors. The text also describes the plasma protein vehicles (transferrin, ceruloplasmin, transthyretin, haptoglobin, hemopexin, and the vitamin D binding protein), as well as cytokines and transcription factors involved in the regulatory process. The protein and gene anatomies are discussed in terms of evolutionary relationships and genetic variations, especially those with mutations causing clinical manifestations. The book also encompasses the mechanisms responsible for tissue specific and developmental expression of plasma protein genes. Geneticists, biochemists, molecular biologists, physicians, and other students of biology will find the book invaluable.

Blood Groups and Red Cell Antigens

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (225 download)

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Book Synopsis Blood Groups and Red Cell Antigens by : Laura Dean

Download or read book Blood Groups and Red Cell Antigens written by Laura Dean and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Blood Cells and Plasma Proteins

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Publisher : Elsevier
ISBN 13 : 1483261409
Total Pages : 461 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Blood Cells and Plasma Proteins by : James L. Tullis

Download or read book Blood Cells and Plasma Proteins written by James L. Tullis and published by Elsevier. This book was released on 2013-10-22 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood Cells and Plasma Proteins: Their State in Nature focuses on the properties, characteristics, reactions, and transformations of blood cells and plasma proteins. The selection first takes a look at the historical prologue on the discovery of the formed and fluid parts of human blood and chemical prologue on the characterization and separation of proteins by virtue of their interactions with neutral salts. The text then takes a look at interactions of proteins with each other and with heavy metals and interactions of proteins with alkaline earths, steroids, blood cells, and polysaccharides. The book then ponders on the components of human plasma concerned with coagulation and the biochemical, physiological, and pathological aspects of the coagulation mechanism. Discussions focus on evolution of the clotting mechanism, modern concepts of clotting, state of accelerator substances, and state of calcium. The text also tackles the nature of immune processes, antibodies in human gamma globulin, and physical characteristics of the gamma globulins. The selection is a valuable reference for readers interested in blood cells and plasma protein.

Amount of Plasma Proteins and Red Blood Cells and the Vascular-extravascular Exchange of Plasma Proteins in the Rat as Measured with I131 and CR51 Labels

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Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Amount of Plasma Proteins and Red Blood Cells and the Vascular-extravascular Exchange of Plasma Proteins in the Rat as Measured with I131 and CR51 Labels by : William C. Dewey

Download or read book Amount of Plasma Proteins and Red Blood Cells and the Vascular-extravascular Exchange of Plasma Proteins in the Rat as Measured with I131 and CR51 Labels written by William C. Dewey and published by . This book was released on 1958 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Iodine Labeled Plasma Proteins

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Publisher : CRC Press
ISBN 13 : 1000697223
Total Pages : 348 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Iodine Labeled Plasma Proteins by : Erwin Regoeczi

Download or read book Iodine Labeled Plasma Proteins written by Erwin Regoeczi and published by CRC Press. This book was released on 2019-07-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1984, this book offers comprehensive insight into iodine labelled proteins in the blood. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of hematology and other practitioners in their respective fields.

Biotechnology of Plasma Proteins

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Publisher : CRC Press
ISBN 13 : 1439850267
Total Pages : 463 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Biotechnology of Plasma Proteins by : Roger L. Lundblad

Download or read book Biotechnology of Plasma Proteins written by Roger L. Lundblad and published by CRC Press. This book was released on 2012-08-08 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to the development of recombinant therapeutic proteins. Discussing the role of plasma proteins in current biotechnology, Biotechnology of Plasma Proteins describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, mass spectrometry, and updates not published since 1975. Key Topics Protein Composition of Plasma Proteomic methods for plasma protein analysis Plasma protein biomarkers Validation of biomarkers Assays for plasma biomarkers Methods for the Analysis of Protein Products Assay development and validation Electrophoresis Chromatography Immunoassay Mass spectrometry Raman spectroscopy Plasma Fractionation: Historical and Modern Methods Development of Cohn alcohol fractionation Industrial methods Development of chromatographic methods Plasma Protein Products of Therapeutic Value Albumin Intravenous immunoglobulin Coagulation products Growth factors Wound management

Structure and Function of Plasma Proteins

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Publisher : Springer Science & Business Media
ISBN 13 : 1468426796
Total Pages : 434 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Structure and Function of Plasma Proteins by : A. Allison

Download or read book Structure and Function of Plasma Proteins written by A. Allison and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 Ontogeny of Human Plasma Proteins: Detection of the Onset and Site of Synthesis Using Genetic Markers and in Vitro Cultures.- 1.1. Introduction.- 1.2. Immunoglobulins.- 1.2.1. Classes and Subclasses and Genetic Markers.- 1.2.2. Synthesis of Ig Molecules at Cellular Level.- 1.2.3. Transfer of Immunoglobulins through the Placenta.- 1.2.4. Synthesis of Immunoglobulins during Fetal Life.- 1.3. Complement.- 1.3.1. The Components of Complement.- 1.3.2. Levels and Fetal Synthesis of the Components of C.- 1.4. Haptoglobin System.- 1.5. Transferrins.- 1.6. ?-Lipoprotein Variants: The Ag and Lp System.