The Ongoing Challenge Of Antimicrobial Resistance An Issue Of Infectious Disease Clinics Of North America Ebook

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The Ongoing Challenge of Antimicrobial Resistance, An Issue of Infectious Disease Clinics of North America, EBook

Author : Richard R. Watkins
Publisher : Elsevier Health Sciences
ISBN 13 : 0323759440
Total Pages : 313 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis The Ongoing Challenge of Antimicrobial Resistance, An Issue of Infectious Disease Clinics of North America, EBook by : Richard R. Watkins

Download or read book The Ongoing Challenge of Antimicrobial Resistance, An Issue of Infectious Disease Clinics of North America, EBook written by Richard R. Watkins and published by Elsevier Health Sciences. This book was released on 2020-11-11 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together with Consulting Editor Dr. Helen Boucher, Drs. Watkins and Bonomo have put together an issue of Infectious Disease Clinics of North America that provides the most current information on antibiotic resistance. Top experts have contributed clinical review articles that address the types of resistance based on drug class as well as emerging therapies and the future of telemedicine in the management of infections. The following topics are covered in this issue: The changing role of the clinical microbiology laboratory in defining resistance in gram-negatives; Extended-spectrum ß-lactamase-producing Enterobacteriaceae infections; Multidrug-resistant bacteria in the community; Resistance to polymyxins; Resistance in Vancomycin-resistant enterococci; Resistance to newer ß-lactamase inhibitors; Antibiotic-resistant infections in the immunocompromised host; Emerging therapies for MRSA infections; Drug-resistant tuberculosis; Aminoglycoside resistance; The role of antibiotic stewardship and telemedicine in the management of MDR infections; and Emerging issues in antifungal resistance. Readers will have the current information they need to better manage antibiotic-resistant infections in patients.

The Ongoing Challenge of Antimicrobial Resistance, an Issue of Infectious Disease Clinics of North America

Author : Richard R. Watkins
Publisher : Elsevier
ISBN 13 : 9780323759434
Total Pages : 240 pages
Book Rating : 4.7/5 (594 download)

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Book Synopsis The Ongoing Challenge of Antimicrobial Resistance, an Issue of Infectious Disease Clinics of North America by : Richard R. Watkins

Download or read book The Ongoing Challenge of Antimicrobial Resistance, an Issue of Infectious Disease Clinics of North America written by Richard R. Watkins and published by Elsevier. This book was released on 2020-09-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together with Consulting Editor Dr. Helen Boucher, Drs. Watkins and Bonomo have put together an issue of Infectious Disease Clinics of North America that provides the most current information on antibiotic resistance. Top experts have contributed clinical review articles that address the types of resistance based on drug class as well as emerging therapies and the future of telemedicine in the management of infections. The following topics are covered in this issue: The changing role of the clinical microbiology laboratory in defining resistance in gram-negatives; Extended-spectrum ?-lactamase-producing Enterobacteriaceae infections; Multidrug-resistant bacteria in the community; Resistance to polymyxins; Resistance in Vancomycin-resistant enterococci; Resistance to newer ?-lactamase inhibitors; Antibiotic-resistant infections in the immunocompromised host; Emerging therapies for MRSA infections; Drug-resistant tuberculosis; Aminoglycoside resistance; The role of antibiotic stewardship and telemedicine in the management of MDR infections; and Emerging issues in antifungal resistance. Readers will have the current information they need to better manage antibiotic-resistant infections in patients.

Antibiotic Resistance: Challenges and Opportunities, An Issue of Infectious Disease Clinics of North America, E-Book

Author : Robert A. Bonomo
Publisher : Elsevier Health Sciences
ISBN 13 : 0323446191
Total Pages : 273 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Antibiotic Resistance: Challenges and Opportunities, An Issue of Infectious Disease Clinics of North America, E-Book by : Robert A. Bonomo

Download or read book Antibiotic Resistance: Challenges and Opportunities, An Issue of Infectious Disease Clinics of North America, E-Book written by Robert A. Bonomo and published by Elsevier Health Sciences. This book was released on 2016-06-11 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, physicians and the public assumed that the discovery of new antimicrobial agents would outpace the ability of bacteria to mutate and develop drug resistance. Yet the development of new antibiotics has not kept up with bacterial evolution, especially since the late 1990’s. At that time a multitude of pharmaceutical companies abandoned antibiotic research because of strong economic disincentives. For example, it is challenging for these companies to recuperate the investment (typically in the hundreds of millions of dollars) made in developing a new antibiotic, which is typically prescribed for a few days, compared to drugs that treat chronic conditions like heart disease or mental illness. This situation has led the U.S. federal government to take a more active lead in addressing antibiotic resistance. Recently, the White House announced an action plan that includes improving surveillance, developing better diagnostic tools, accelerating drug development, and improving global coordination of antibiotic resistance issues. Equally important is the $1.2 billion dollars that has been pledged to fund these efforts. While we await the implementation of new policies, this issue of Infectious Disease Clinics of North America brings together leading authorities in the field of antibiotic resistance who discuss current issues including antibiotic stewardship, the changing role of the microbiology laboratory in determining antibiotic resistance in gram-negative pathogens, the continuing spread of metallo-β-lactamases, ESBLs and KPCs, antibiotic options for treating resistant gram-negative infections such as colistin and tigecycline, resistance mechanisms and new treatment options for Mycobacterium tuberculosis, emerging resistance mechanisms in aminoglycosides, issues with antibiotic resistance in immunocompromised patients, new β-lactamase inhibitors in the clinic, and resistance in VRE and Staphylococcus aureus. Additionally, combination therapy for resistant gram-negative infections has been advocated by some authorities and the advantages and disadvantages of this strategy will be reviewed.

Antimicrobial Stewardship: Where We’ve Come and Where We’re Going, An Issue of Infectious Disease Clinics of North America, E-Book

Author : Emily Sydnor Spivak
Publisher : Elsevier Health Sciences
ISBN 13 : 0443130841
Total Pages : 314 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Antimicrobial Stewardship: Where We’ve Come and Where We’re Going, An Issue of Infectious Disease Clinics of North America, E-Book by : Emily Sydnor Spivak

Download or read book Antimicrobial Stewardship: Where We’ve Come and Where We’re Going, An Issue of Infectious Disease Clinics of North America, E-Book written by Emily Sydnor Spivak and published by Elsevier Health Sciences. This book was released on 2023-10-27 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Infectious Disease Clinics of North America, guest editors Drs. Emily Sydnor Spivak and Sage Greenlee bring their considerable expertise to the topic of Antimicrobial Stewardship: Where We Have Come and Where We Are Going. Throughout the last decade, the field of antimicrobial stewardship has undergone exponential growth due to heightened awareness of antimicrobial use and emerging multidrug-resistant organisms. Additionally, the COVID-19 pandemic highlighted systemic and persistent health disparities in the United States. In this issue, top experts provide a recap of the progress made over the last decade in antimicrobial stewardship and provide direction for next steps in this ever-growing field. Contains 12 practice-oriented topics including antimicrobial stewardship and pandemic preparedness: lessons learned from COVID-19; health equity considerations; antimicrobial stewardship at transitions of care; antimicrobial stewardship in immunocompromised populations; health system and tele-antimicrobial stewardship: the role of building networks; and more. Provides in-depth clinical reviews on antimicrobial stewardship, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Antimicrobial Resistance

Author : Polly F. Harrison
Publisher : National Academies Press
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Antimicrobial Resistance by : Polly F. Harrison

Download or read book Antimicrobial Resistance written by Polly F. Harrison and published by National Academies Press. This book was released on 1998 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic resistance is neither a surprising nor a new phenomenon. It is an increasingly worrisome situation, however, because resistance is growing and accelerating while the world's tools for combating it decrease in power and number. In addition, the cost of the problem--especially of multidrug resistance--in terms of money, mortality, and disability are also rising. This book summarizes a workshop on antimicrobial resistance held by the Forum on Emerging Infections. The goal of the Forum on Emerging Infections is to provide an opportunity for representatives of academia, industry, government, and professional and interest groups to examine and discuss scientific and policy dilemmas of common interest that are specifically related to research on and the prevention, detection, and management of emerging infections. Organized as a topic-by-topic synthesis of presentations and exchanges during the workshop, the book highlights lessons learned, delineates a range of pivotal issues and the problems they raise, and proposes some simplified ideas about possible responses.

21st Century Challenges in Antimicrobial Therapy and Stewardship

Author : Islam M Ghazi
Publisher :
ISBN 13 : 9789811461828
Total Pages : 492 pages
Book Rating : 4.4/5 (618 download)

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Book Synopsis 21st Century Challenges in Antimicrobial Therapy and Stewardship by : Islam M Ghazi

Download or read book 21st Century Challenges in Antimicrobial Therapy and Stewardship written by Islam M Ghazi and published by . This book was released on 2020-11-19 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: 21st Century Challenges in Antimicrobial Therapy and Stewardship addresses selected topics that are of importance in the practice of infectious disease management. The text starts by illustrating the global landscape of antimicrobial drug resistance, which influences antimicrobial use and therapeutic decisions in the clinic. The contributors explain the reasons for the spread of antibiotic resistance, the pharmacology of antibiotics of different classes, innovative drug delivery methods which can improve the efficacy and safety of new drug candidates and achieve targeted drug delivery as well as drug resistance monitoring techniques and issues in the practice of antimicrobial stewardship and infection control.Key Features: - 14 organized chapters on several aspects of antimicrobial therapy and stewardship- Introductory knowledge on global antimicrobial trends- Coverage of molecular basis of antimicrobial resistance in gram positive, gram negative and fungal microbes- Focused coverage on new developments in antimicrobial drug development, drug delivery, formulation and diagnostic tools- Information on unmet needs of patients and clinicians, including the treatment of difficult infections- Comprehensive coverage of issues in antimicrobial stewardship21st Century Challenges in Antimicrobial Therapy and Stewardship brings to readers - healthcare administrators, educators, pharmacists, clinicians and students, alike - the knowledge of the molecular basis of antimicrobial drug therapy, drug resistance in pathogens and current practices in antimicrobial stewardship programs. This knowledge, in turn, fosters an awareness among healthcare industry participants to collaborate in an interprofessional environment to combat multidrug resistanc

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Current Status and Challenge of Antimicrobial Resistance in China

Author : Minggui Wang
Publisher :
ISBN 13 :
Total Pages : 139 pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis Current Status and Challenge of Antimicrobial Resistance in China by : Minggui Wang

Download or read book Current Status and Challenge of Antimicrobial Resistance in China written by Minggui Wang and published by . This book was released on 2018 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine

Author : National Academies Of Sciences Engineeri
Publisher : National Academies Press
ISBN 13 : 9780309269452
Total Pages : pages
Book Rating : 4.2/5 (694 download)

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Book Synopsis Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine by : National Academies Of Sciences Engineeri

Download or read book Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2022-07-20 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.

Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy, An Issue of Infectious Disease Clinics of North America, Ebook

Download Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy, An Issue of Infectious Disease Clinics of North America, Ebook PDF Online Free

Author : Jo-Anne Young
Publisher : Elsevier Health Sciences
ISBN 13 : 0323678734
Total Pages : 345 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy, An Issue of Infectious Disease Clinics of North America, Ebook by : Jo-Anne Young

Download or read book Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy, An Issue of Infectious Disease Clinics of North America, Ebook written by Jo-Anne Young and published by Elsevier Health Sciences. This book was released on 2019-06-28 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: In collaboration with Consulting Editor, Dr. Helen Boucher, Dr. Jo-Ann Young has put together a state-of the-art issue of the Infectious Disease Clinics of North America devoted to Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy. Clinical review articles from expert authors are specifically devoted to the following topics, addressing both the stem cell transplant recipient and the hematologic malignancy patient: Chemotherapy Regimens for Hematologic Malignancies and Issues That Affect Infection; Stem Cell Transplantation Technical Issues That Affect Infection in The Recipient; Complications of Stem Cell Transplantation That Cause Infections; Antimicrobial Prophylaxis and Preemptive Agents and Regimens for the Prevention of Infection; Workup for Fever During Neutropenia; Herpesvirus Infections; Cytomegalovirus Infections; Respiratory Virus Infections; Other DNA Virus Infections; Bacterial Infections; Fungal Infections; Parasitic Infections; Vaccination; and Immunoglobulin Replacement. Readers will come away with the latest information they need to manage infections and improve outcomes in these patients.

Textbook of Veterinary Internal Medicine - eBook

Author : Stephen J. Ettinger
Publisher : Elsevier Health Sciences
ISBN 13 : 032331239X
Total Pages : 2736 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Textbook of Veterinary Internal Medicine - eBook by : Stephen J. Ettinger

Download or read book Textbook of Veterinary Internal Medicine - eBook written by Stephen J. Ettinger and published by Elsevier Health Sciences. This book was released on 2017-01-11 with total page 2736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your days spent fruitlessly scouring textbooks and websites for credible vet information are over! Now you can get the whole story — the accurate story — all in one place. Introducing The Textbook of Veterinary Internal Medicine, Expert Consult, 8th Edition. Still the only comprehensive resource for veterinary internal medical problems, this faculty-and-student-favorite offers unparalleled coverage of pathophysiology, diagnosis, and disease treatments for dogs and cats. In addition to new chapters and discussions on the industry’s most topical issues, this "gold standard in vet medicine" comes with hundreds of original videos, algorithms, and learning tools to really bring all the information to life. There’s no better source to help you unlock the secrets of veterinary medicine than Ettinger’s! Fully searchable online text offers quick access to the most trusted information in the field. Complete library of over 500 original clinical videos you can believe in. Instead of fruitless YouTube searches, each video expertly breaks down veterinary procedures and important signs of diseases and disorders that are difficult or impossible to understand from written descriptions alone. In-depth coverage of timely issues includes expert explanations on topics such as the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, and cancer vaccines. Thousands of references accessible from the printed book with the click of a QR code. 256 all-new client information sheets can be downloaded, customized, and printed as client handouts. 214 new and updated clinical algorithms aid in disease identification and decision-making. Exclusive access to Expert Consult Online website offers the complete library of original video clips, heart sounds, the full collection of client information sheets, and hyperlinking of references to their source abstracts in PubMed. NEW! In-depth coverage of the latest information and trends in small animal internal medicine. Completely new section on minimally-invasive interventional procedures includes techniques for treating respiratory, cardiovascular, gastrointestinal, urologic/nephrologic, and neoplastic disorders. 17 new chapters address the major clinicopathologic abnormalities that occur in canine and feline laboratory testing. Completely new section on management of mutually-antagonistic comorbidities spotlights concurrent cardiac and renal disease, concurrent infection in patients requiring immunosuppression, and concurrent diabetes mellitus and corticosteroid-dependent disease. Expert explanations on topics such as evidence-based medicine, distinguishing behavioral disorders from medical neurologic disorders, blood transfusion techniques, hyperadrenocorticism (Cushing’s disease), chronic kidney disease, respiratory and inhalant therapy, and many more.

WHO guidelines on use of medically important antimicrobials in food-producing animals

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9789241550130
Total Pages : 0 pages
Book Rating : 4.5/5 (51 download)

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Book Synopsis WHO guidelines on use of medically important antimicrobials in food-producing animals by : World Health Organization

Download or read book WHO guidelines on use of medically important antimicrobials in food-producing animals written by World Health Organization and published by World Health Organization. This book was released on 2017-11-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO has launched new guidelines on use of medically important antimicrobials in food-producing animals, recommending that farmers and the food industry stop using antibiotics routinely to promote growth and prevent disease in healthy animals. These guidelines aim to help preserve the effectiveness of antibiotics that are important for human medicine by reducing their use in animals.

Cases in Medical Microbiology and Infectious Diseases

Author : Peter H. Gilligan
Publisher : John Wiley & Sons
ISBN 13 : 1683673433
Total Pages : 579 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Cases in Medical Microbiology and Infectious Diseases by : Peter H. Gilligan

Download or read book Cases in Medical Microbiology and Infectious Diseases written by Peter H. Gilligan and published by John Wiley & Sons. This book was released on 2014-08-01 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cases in Medical Microbiology and Infectious Diseases challenges students to develop a working knowledge of the variety of microorganisms that cause infections in humans. This valuable, interactive text will help them better understand the clinical importance of the basic science concepts presented in medical microbiology or infectious disease courses. The cases are presented as "unknowns" and represent actual case presentations of patients the authors have encountered. Each case is accompanied by several questions to test knowledge in four broad areas including the organism's characteristics and laboratory diagnosis; pathogenesis and clinical characteristics of the infection; epidemiology; and prevention and, in some cases, drug resistance and treatment. This new fourth edition includes: an entirely new section, "Advanced Cases," which includes newly recognized disease agents as well as highly complex cases where the interaction of the immune system and human pathogens can be more closely examined a revised "Primer on the Laboratory Diagnosis of Infectious Diseases" section that reflects the increasing importance of molecular-based assays Forty-two new cases that explore the myriad advances in the study of infectious disease in the past decade Thirty-two updated cases that reflect the current state of the art as it relates to the organism causing the infection This textbook also include specific tools to assist students in solving the cases, including a table of normal values, glossary of medical terms, and figures illustrating microscopic organism morphology, laboratory tests, and clinical symptoms. Cases in Medical Microbiology and Infectious Diseases is a proven resource for preparing for Part I of the National Board of Medical Examiners Exam and an excellent reference for infectious disease rotations.

The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309030447
Total Pages : 393 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds by : National Research Council

Download or read book The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds written by National Research Council and published by National Academies Press. This book was released on 1980-02-01 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Red Book Atlas of Pediatric Infectious Diseases

Author : American Academy of Pediatrics
Publisher :
ISBN 13 : 9781581102475
Total Pages : 440 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Red Book Atlas of Pediatric Infectious Diseases by : American Academy of Pediatrics

Download or read book Red Book Atlas of Pediatric Infectious Diseases written by American Academy of Pediatrics and published by . This book was released on 2007 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on key content from Red Book: 2006 Report of the Committee on Infectious Diseases, 27th Edition, the new Red Bookr Atlas is a useful quick reference tool for the clinical diagnosis and treatment of more than 75 of the most commonly seen pediatric infectious diseases. Includes more than 500 full-color images adjacent to concise diagnostic and treatment guidelines. Essential information on each condition is presented in the precise sequence needed in the clinical setting: Clinical manifestations, Etiology, Epidemiology, Incubation period, Diagnostic tests, Treatment

Antimicrobial Resistance

Author : World Health Organization
Publisher :
ISBN 13 : 9789241564748
Total Pages : 232 pages
Book Rating : 4.5/5 (647 download)

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Book Synopsis Antimicrobial Resistance by : World Health Organization

Download or read book Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2014 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

Human Challenge Studies in Endemic Settings

Author : Euzebiusz Jamrozik
Publisher : Springer Nature
ISBN 13 : 3030414809
Total Pages : 145 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Human Challenge Studies in Endemic Settings by : Euzebiusz Jamrozik

Download or read book Human Challenge Studies in Endemic Settings written by Euzebiusz Jamrozik and published by Springer Nature. This book was released on 2020 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income countries (LMICs). Human challenge studies (HCS) involve the intentional infection of research participants, and this type of research is rapidly increasing in frequency worldwide. HCS are widely considered to be an especially promising approach to vaccine development, including for pathogens endemic to LMICs. However, challenge studies are sometimes controversial and raise complex ethical issues, some of which are especially salient in endemic and/or LMIC settings. Informed by qualitative interviews with experts in infectious diseases and bioethics, this book highlights areas of ethical consensus and controversy concerning this kind of research. As the first volume to focus on ethical issues associated with human challenge studies, it sets the agenda for further work in this important area of global health research; contributes to current debates in research ethics; and aims to inform regulatory policy and research practice. Insofar as it focuses on HCS in (endemic) settings where diseases are present and/or widespread, much of the analysis provided here is directly relevant to HCS involving pandemic diseases including COVID19.