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Author : R. Eugene Ramsay
Publisher : Academic Press
ISBN 13 : 0123740185
Total Pages : 362 pages
Book Rating : 4.1/5 (237 download)
Download or read book Neurobiology of Epilepsy and Aging written by R. Eugene Ramsay and published by Academic Press. This book was released on 2007-04-16 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses all aspects of epilepsy in aging patients.
Author : R. Eugene Ramsay
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (122 download)
Download or read book The Neurobiology of Epilepsy and Aging written by R. Eugene Ramsay and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Günter Krämer
Publisher : Thieme
ISBN 13 : 9783131053213
Total Pages : 232 pages
Book Rating : 4.0/5 (532 download)
Download or read book Epilepsy in the Elderly written by Günter Krämer and published by Thieme. This book was released on 1999 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a systematic description of the advantages and disadvantages of individual drugs for the elderly and provides orientation by means of numerous tables which list, among others, drug interactions and special features in cases of liver and kidney disease, including hemodialysis.
Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author : A. J. Rowan
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)
Download or read book Seizures and Epilepsy in the Elderly written by A. J. Rowan and published by Butterworth-Heinemann. This book was released on 1997 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epileptic seizures in the elderly population occur more frequently that previously thought. Recent epidemiologic data indicate that the incidence of seizures rises sharply after middle age. Seizures occur because of previous stroke or head trauma in addition to a variety of systemic derangements, drugs, drug withdrawal, or acute intracranial disease. The aging process creates particular problems in diagnosis, specific therapy, and long-term management. Prompt diagnosis and therapy are essential. This bookemphasizes the physiologic and pathologic changes associated with aging that have an impact on diagnosis and treatment. It will include epidemiology, clinical diagnosis, imaging and electrophysiologic studies, age-related physiologic changes, pharmacokinetics, drug interactions, current and new antiepileptic drugs, and management.
Author : Jerome Engel Jr
Publisher : Oxford University Press
ISBN 13 : 019532854X
Total Pages : 737 pages
Book Rating : 4.1/5 (953 download)
Download or read book Seizures and Epilepsy written by Jerome Engel Jr and published by Oxford University Press. This book was released on 2013-01-31 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.
Author : Jeffrey Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)
Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Author : Aristea S. Galanopoulou
Publisher : Biota Publishing
ISBN 13 : 1615043551
Total Pages : 72 pages
Book Rating : 4.6/5 (15 download)
Download or read book Seizures and the Developing Brain written by Aristea S. Galanopoulou and published by Biota Publishing. This book was released on 2011-10-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seizures are more common early in life than in adulthood. Bidirectional interactions between seizures and normal developmental processes define their expression and outcomes. Several developmentally regulated factors control neuronal excitability. GABAA receptors hold a central role as they control neuronal activity in an age-specific manner. Early in development, GABAA receptors have depolarizing effects, which contribute to the increased susceptibility of immature neurons to seizures but they are also essential for normal brain development. During development, there is a gradual shift to the "adult-type" hyperpolarizing GABAA receptor signaling, creating more efficient inhibition. Seizures may disrupt GABAA receptor signaling by changing the expression of their subunits and by changing the direction of GABAA responses, which, in certain situations, may be detrimental for brain development. Furthermore, subcortical nuclei, such as the substantia nigra, control the expression and propagation of seizures in an age- and sex-dependent manner. These endogenous control centers and signaling pathways are further modified by independent genetic epigenetic, biologic, or other factors, which further increase the heterogeneity in presentation of seizures, their treatment, and their comorbidities. Elucidation of these complex interactions and identification of biomarkers guiding therapeutic interventions will be necessary to improve our ability to treat early-life epilepsies.
Author : Samden D. Lhatoo
Publisher : Oxford University Press
ISBN 13 : 0192569473
Total Pages : 577 pages
Book Rating : 4.1/5 (925 download)
Download or read book Invasive Studies of the Human Epileptic Brain written by Samden D. Lhatoo and published by Oxford University Press. This book was released on 2018-11-15 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: No other neurological condition allows the same opportunities for an intracranial electrophysiological study of the human brain as epilepsy does. Epileptic surgery is designed to remove the epileptic focus from the human brain, thereby effecting either cure or substantial reduction of seizures in an individual with an otherwise intractable condition. Its use as a treatment modality dates from the late 19th century, and it has become a widely used treatment option throughout the world in the last 20-30 years. The complexity of epilepsy cases in surgical centres, and the need for invasive electrode studies for pre-surgical evaluation, are both greatly increasing. Invasive Studies of the Human Epileptic Brain is the definitive reference text on the use of invasive electroencephalographic (EEG) diagnostic studies in human epilepsy. Written by some of the most renowned epilepsy experts of the 20th and 21st centuries, the authors provide their expertise and insights into the identification and mapping of intracranial epileptiform and non-epileptiform activity, mapping of the human brain function, and approaches in the use of invasive electroencephalography in a variety of clinical situations. The book is organized into an easily readable series of chapters and is brilliantly illustrated with case studies; each providing an intuitively comprehensive approach to invasive brain studies.
Author : Joseph I. Tracy
Publisher : Oxford University Press, USA
ISBN 13 : 0199965242
Total Pages : 433 pages
Book Rating : 4.1/5 (999 download)
Download or read book Cognitive Plasticity in Neurologic Disorders written by Joseph I. Tracy and published by Oxford University Press, USA. This book was released on 2014-12-02 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.
Author : Claude G. Wasterlain
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128077514
Total Pages : 40 pages
Book Rating : 4.1/5 (28 download)
Download or read book Pediatric Neurology Part I written by Claude G. Wasterlain and published by Elsevier Inc. Chapters. This book was released on 2013-04-24 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neonatal brain has poorly developed GABAergic circuits, and in many of them GABA is excitatory, favoring ictogenicity. Frequently repeated experimental seizures impair brain development in an age-dependent manner. At critical ages, they delay developmental milestones, permanently lower seizure thresholds, and can cause very specific cognitive and learning deficits, such as the permanent impairment of neuronal spatial maps. Some types of experimental status epilepticus cause neuronal necrosis and apoptosis, and are followed by chronic epilepsy with spontaneous recurrent seizures, others appear relatively benign, so that seizure-induced neuronal injury and epileptogenesis are highly age-, seizure model-, and species-dependent. Experimental febrile seizures can be epileptogenic, and hyperthermia aggravates both neuronal injury and epileptogenicity. Antiepileptic drugs, the mainstay of treatment, have major risks of their own, and can, at therapeutic or near-therapeutic doses, trigger neuronal apoptosis, which is also age-, drug-, cell type-, and species-dependent. The relevance of these experimental results to human disease is still uncertain, but while their brains are quite different, the basic biology of neurons in rodents and humans is strikingly similar. Further research is needed to elucidate the molecular mechanisms of epileptogenesis and of seizure- or drug-induced neuronal injury, in order to prevent their long-term consequences.
Author : Samden Lhatoo
Publisher : Oxford University Press, USA
ISBN 13 : 0199659044
Total Pages : 395 pages
Book Rating : 4.1/5 (996 download)
Download or read book Oxford Textbook of Epilepsy and Epileptic Seizures written by Samden Lhatoo and published by Oxford University Press, USA. This book was released on 2012-12-20 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.
Author : Isabelle Jambaqué
Publisher : Springer Science & Business Media
ISBN 13 : 0306476126
Total Pages : 296 pages
Book Rating : 4.3/5 (64 download)
Download or read book Neuropsychology of Childhood Epilepsy written by Isabelle Jambaqué and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the neuropsychological description of childhood epilepsy, a neurolo- cal condition that constitutes one of the most prevalent forms of chronic and disabling childhood illnesses. Indeed, one child out of 20 experiences one or more seizures before the age of 5, and one in a hundred develops epilepsy as a chronic disorder. Approximately half of these children with epilepsy display academic difficulties and/or behavioral disorders. Moreoever, it is now believed that a sizable proportion of children with learning disability suffer from undiagnosed epilepsy. While a great number of textbooks have been devoted to various medical aspects of chi- hood epilepsy (diagnosis, genetics, etiology, drug and surgical treatment, etc.), there have been no comprehensive accounts of the cognitive consequences of this condition. Advance of medical knowledge has shown that childhood epilepsy should not be considered as a single disorder but encompasses a whole range of different conditions that exhibit specific clinical EEG and outcome characteristics. It is not becoming apparent that these various clinical entities have different cognitive expression that yet need to be specified. The purpose of this book is to provide a complete up-to-date analysis of this multi-faceted pathology.
Author : Marco Mula
Publisher : Academic Press
ISBN 13 : 0128148780
Total Pages : 416 pages
Book Rating : 4.1/5 (281 download)
Download or read book The Comorbidities of Epilepsy written by Marco Mula and published by Academic Press. This book was released on 2019-04-20 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. - Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy - Discusses up-to-date management of comorbidities of epilepsy - Written by a group of international experts in the field
Author : Vikram Patel
Publisher : World Bank Publications
ISBN 13 : 1464804281
Total Pages : 307 pages
Book Rating : 4.4/5 (648 download)
Download or read book Disease Control Priorities, Third Edition (Volume 4) written by Vikram Patel and published by World Bank Publications. This book was released on 2016-03-10 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.
Author : Martin L. Albert
Publisher : Oxford University Press, USA
ISBN 13 : 9780195071672
Total Pages : 740 pages
Book Rating : 4.0/5 (716 download)
Download or read book Clinical Neurology of Aging written by Martin L. Albert and published by Oxford University Press, USA. This book was released on 1994 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thorough revision of a well-established text presents essential information on the neurobiology of aging. There are new chapters on competency and ethics, problems of daily living, psychopharmacology, and stability and falls. Written in a accessible style, this book will be invaluable to clinicians and neurologists who treat elderly patients.
Author : Asla Pitkänen
Publisher : Academic Press
ISBN 13 : 012804067X
Total Pages : 1180 pages
Book Rating : 4.1/5 (28 download)
Download or read book Models of Seizures and Epilepsy written by Asla Pitkänen and published by Academic Press. This book was released on 2017-06-14 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
