The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine

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Author :
Publisher : Academic Press
ISBN 13 : 0128133635
Total Pages : 304 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine by : Uri Galili

Download or read book The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine written by Uri Galili and published by Academic Press. This book was released on 2017-09-05 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the α-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book. Provides tactics on how to improve cancer immunotherapy and viral vaccine immunogenicity Includes discussions on therapies that accelerate the healing of normal and chronic wounds, and of burns Covers the regeneration of bio-implants

α–Gal and Anti–Gal

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461547717
Total Pages : 404 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis α–Gal and Anti–Gal by : Uri Galili

Download or read book α–Gal and Anti–Gal written by Uri Galili and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uri Galili who originally discovered anti-Gal and the unique evolution of &agr;-1,3-galactosyltransferase, and by Dr. Jose-Luis Avila who has been studying anti-Gal significance in Chagas' disease and in Leishmania infections. This book covers the main areas of research on &agr;-1,3galactosyltransferase, its product the &agr;-gal epitope (Gal&agr;1-3Gal&bgr;1-4GlcNAc-R) and the natural anti-Gal antibody that interacts with this epitope

α–Gal and Anti–Gal

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Publisher : Springer
ISBN 13 : 9781461547723
Total Pages : 394 pages
Book Rating : 4.5/5 (477 download)

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Book Synopsis α–Gal and Anti–Gal by : Uri Galili

Download or read book α–Gal and Anti–Gal written by Uri Galili and published by Springer. This book was released on 1999 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sphingolipids in Cancer

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Publisher : Academic Press
ISBN 13 : 0128142243
Total Pages : 410 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Sphingolipids in Cancer by :

Download or read book Sphingolipids in Cancer written by and published by Academic Press. This book was released on 2018-07-27 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of ceramide-dependent cancer cell death, Sphingolipids as regulators of autophagy and endocytic trafficking, The role and function of sphingomyelin biosynthesis in the development of cancer, Neutral sphingomyelinases in cancer: Friend or foe?, Sphingolipid rendezvous at the crossroad of NAFLD and senescence, Ceramide signaling and p53 pathways, Sphingolipid regulation of RNA Biology in cancer phenotypes, The role of ceramide-1-phosphate in tumor cell survival and dissemination, and more. Provides information on cancer research, with this release focusing on sphingolipids Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Carbohydrate Antigens

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Publisher :
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Carbohydrate Antigens by : Per J. Garegg

Download or read book Carbohydrate Antigens written by Per J. Garegg and published by . This book was released on 1993 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed from a symposium at the Fourth Chemical Congress of North America (202nd National Meeting of the ACS) in New York City, August 1991, chapter-papers present research on topics including how proteins recognize and bind oligosaccharides, synthesis and immunological properties of glycopeptide T-cell determinants, Vibrio cholerae polysaccharide studies, and purification of oligosaccharide antigens by weak affinity chromatography. Annotation copyright by Book News, Inc., Portland, OR

The Hostage Brain

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Publisher : Rockefeller Univ. Press
ISBN 13 : 9780874700565
Total Pages : 336 pages
Book Rating : 4.7/5 (5 download)

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Book Synopsis The Hostage Brain by : Bruce S. McEwen

Download or read book The Hostage Brain written by Bruce S. McEwen and published by Rockefeller Univ. Press. This book was released on 1994 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fabry Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 9048190339
Total Pages : 525 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Fabry Disease by : Deborah Elstein

Download or read book Fabry Disease written by Deborah Elstein and published by Springer Science & Business Media. This book was released on 2010-08-02 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fabry disease is an X-linked inborn error of metabolism wherein deficiency of a lysosomal enzyme results in systemic deposition of glycosphingolipids. Storage deposition, and hence pathological disease, occurs preferentially in renal glomerular and tubular epithelial cells, myocardial cells, heart valve fibrocytes, neurons of dorsal root ganglia, and in endothelial smooth muscle cells of blood vessels. Thus, Fabry disease is a multi-system disorder, albeit with considerable phenotypic heterogeneity in onset and in severity; however, it is progressive, exhibits extensive morbidity, and is life-threatening. Within the past two decades, there has been a radical change in the natural course Fabry disease by virtue of the availability of specific enzyme replacement therapy. Moreover, there has been a concerted effort to better understand the underlying pathology and equally to identify patients prior to the onset of irreversible end-organ damage. It is to be hoped that the future for patients with Fabry disease can be viewed with greater, albeit guarded, optimism. This state-of-the-art textbook attempts to bridge the span of pre-clinical studies, clinical finding, and management options in a readable but comprehensive manner for the medical practitioner as well as the interested non-medical reader.

Dietary Fiber

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Publisher : Springer Science & Business Media
ISBN 13 : 1461305195
Total Pages : 499 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Dietary Fiber by : David Kritchevsky

Download or read book Dietary Fiber written by David Kritchevsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty years ago the very idea of an international conference on the fiber contained in plant food would have been totally inconceivable. At that time fiber was generally viewed as an inert component of food of no nutritional value and consequently consid ered as a contaminant, the removal of which would enhance the purity of a product. It was measured by a now obsolete and almost worthless test introduced in the last century for veterinary rather than human nutrition, and what was measured was referred to as "crude fiber," containing part of the cellulose and lignin but none of the numerous components of fiber now known to play important roles in the maintenance of health. There were a few lone voices prior to the last two decades who had extolled the laxative properties of the undigested portion of food, assuming that these were related to its irritant action on the bowel mucosa. In retrospect this was a total misconception, and "softage" would have been a more appropriate term than "roughage," since its presence insured soft, not irritating, colon content.

Microbial Products for Health, Environment and Agriculture

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Author :
Publisher : Springer Nature
ISBN 13 : 9811619476
Total Pages : 381 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Microbial Products for Health, Environment and Agriculture by : Pankaj Kumar Arora

Download or read book Microbial Products for Health, Environment and Agriculture written by Pankaj Kumar Arora and published by Springer Nature. This book was released on 2021-09-21 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume discusses the role of various microbial products in healthcare, environment and agriculture. Several microbial products are directly involved in solving major health problems, agricultural and environmental issues. In healthcare sector, microbes are used as anti-tumor compounds, antibiotics, anti-parasitic agents, enzyme inhibitors and immunosuppressive agents. Microbial products are also used to degrade xenobiotic compounds and bio-surfactants, for biodegradation process. In agriculture, microbial products are used to enhance nutrient uptake, to promote plant growth, or to control plant diseases. The book presents several such applications of microbes in the ecosystems. The chapters are contributed from across the globe and contain up-to-date information. This book is of interest to teachers, researchers, microbiologists and ecologists. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences.

Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems

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Publisher : Springer
ISBN 13 : 3030171485
Total Pages : 869 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems by : Kevin L. Williams

Download or read book Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems written by Kevin L. Williams and published by Springer. This book was released on 2019-07-24 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects. The intersection of test activities includes the use of an ancient blood system from an odd “living fossil” (Limulus). It is used to detect remnants of the most primitive and destructive forms of life (prokaryotes) as contaminants of complex modern systems (mammalian and Pharma). Recent challenges in the field include those associated with the application of traditional methods to new types of molecules and manufacturing processes. The advent of “at will” production of biologics in lieu of harvesting animal proteins has revolutionized the treatment of disease. While the fruits of the biotechnology revolution are widely acknowledged, the realization of the differences in the means of production and changes in the manner of control of potential impurities and contaminants in regard to the new versus the old are less widely appreciated. Endotoxin as an ancient, dynamic interface between lifeforms, provides a singular perspective from which to view the parallel development of ancient and modern organisms as well as the progress of man in deciphering the complexity of their interactions in his efforts to overcome disease.

Essentials of Glycobiology

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Author :
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)

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Book Synopsis Essentials of Glycobiology by : Ajit Varki

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Nutrient Metabolism

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Publisher : Elsevier
ISBN 13 : 0080537898
Total Pages : 840 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Nutrient Metabolism by : Martin Kohlmeier

Download or read book Nutrient Metabolism written by Martin Kohlmeier and published by Elsevier. This book was released on 2003-10-01 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source. Key Features * Highly illustrated with relevant chemical structures and metabolic pathways * Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry * First comprehensive work on the subject

The Perfect Slime

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Publisher : IWA Publishing
ISBN 13 : 1780407416
Total Pages : 336 pages
Book Rating : 4.7/5 (84 download)

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Book Synopsis The Perfect Slime by : Hans-Curt Flemming

Download or read book The Perfect Slime written by Hans-Curt Flemming and published by IWA Publishing. This book was released on 2016-09-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?

Pediatric Hepatology and Liver Transplantation

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Author :
Publisher : Springer
ISBN 13 : 3319964003
Total Pages : 829 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Pediatric Hepatology and Liver Transplantation by : Lorenzo D'Antiga

Download or read book Pediatric Hepatology and Liver Transplantation written by Lorenzo D'Antiga and published by Springer. This book was released on 2019-04-29 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and transition to adult care. Key topics in the field of liver transplantation are then addressed. Examples include indications and contraindications, surgical techniques and complications, immunosuppression, in pediatric liver transplantation, acute and chronic rejection and allograft dysfunction, and CMV and EBV infection in transplant recipients, long-term graft injury and tolerance. A section on pediatric hepatology across the world includes chapters presenting the features and management of pediatric liver disease in South-America, Africa and Asia. A closing section considers what the future holds for pediatric liver disease and its management, including novel genetic testing, cell therapy and gene therapy. Pediatric Hepatology and Liver Transplantation will be of value for a range of practitioners, from residents making their first approach to pediatric liver disease through to specialists working in transplantation centers.

Computer-Aided Vaccine Design

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Publisher : Elsevier
ISBN 13 : 1908818417
Total Pages : 164 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis Computer-Aided Vaccine Design by : Joo Chuan Tong

Download or read book Computer-Aided Vaccine Design written by Joo Chuan Tong and published by Elsevier. This book was released on 2013-07-31 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics. Essential reading for any biologist who wants to understand methods of computer-aided vaccine design Description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses Theoretical concepts and practical examples of database design and development for a virtual screening campaign

Essential Immunology

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Author :
Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.:/5 (42 download)

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Book Synopsis Essential Immunology by : Ivan Maurice Roitt

Download or read book Essential Immunology written by Ivan Maurice Roitt and published by Wiley-Blackwell. This book was released on 1971 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Veterinary Toxicology for Australia and New Zealand

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Author :
Publisher : Elsevier
ISBN 13 : 0127999124
Total Pages : 628 pages
Book Rating : 4.1/5 (279 download)

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Book Synopsis Veterinary Toxicology for Australia and New Zealand by : Rosalind Dalefield

Download or read book Veterinary Toxicology for Australia and New Zealand written by Rosalind Dalefield and published by Elsevier. This book was released on 2017-06-23 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Toxicology for Australia and New Zealand is a reference suited to the unique challenges of veterinary practice in Australia and New Zealand. Both streamlined and thorough in its coverage of poisons and treatments for those locations, this focused approach allows readers to quickly find relevant information that is presented in a concise and logical manner that is useful to clinicians. The authors draw upon a wealth of knowledge of the particularities of toxicology in Australia and New Zealand to present readers with the up-to-date information required to efficiently and effectively diagnose and treat their patients. Highlights toxins of specific concern in Australia and New Zealand Structures information in a logical way so that it can be located quickly Offers up-to-date information on current and emerging risks