Basic Neurochemistry

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Publisher : Academic Press
ISBN 13 : 0080959016
Total Pages : 1120 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Basic Neurochemistry by : Scott Brady

Download or read book Basic Neurochemistry written by Scott Brady and published by Academic Press. This book was released on 2011-11-02 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475

The Na, K-ATPase

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Author :
Publisher : R. G. Landes
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Na, K-ATPase by : Jean-Daniel Horisberger

Download or read book The Na, K-ATPase written by Jean-Daniel Horisberger and published by R. G. Landes. This book was released on 1994 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text addresses the question, How does the sodium pump pump'. A variety of primary structure information is available, and progress has been made in the functional characterization of the Na, K-pump, making the answer to this question possible, within reach of currently used techniques

Cardiac Glycosides 1785–1985

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Publisher : Springer Science & Business Media
ISBN 13 : 3662112922
Total Pages : 544 pages
Book Rating : 4.6/5 (621 download)

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Book Synopsis Cardiac Glycosides 1785–1985 by : E. Erdmann

Download or read book Cardiac Glycosides 1785–1985 written by E. Erdmann and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bicentenary of William Withering's now famous medical report entitled "An Account of the Foxglove and Some of its Medical Uses" has given us the occasion to analyze the state of the art. Cardiac glycosides in 1985 are considered tobe the basis for medical treatment of myocardial failure, together with diuretics and vasodilators in the more severe cases. Nevertheless, the controversy as to their exact place in the treatment of heart failure with sinus rhythm has never ceased. Although cardiac glycosides are of unquestionable value in tachycardia caused by atrial fibrillation or atrial flutter, the chronic use of these drugs in sinus rhythm is not generally accepted. The development of tolerance has been reported. It is of interest that Withering hirnself wrote: "-let it (foxglove) be continued until it either acts on the kidneys, the stomach, the pulse, or the bowels; Iet it be stopped upon the first appearance of any of these effects, and I will maintain that the patient will not suffer from its exhibition, nor the practitioner be disappointed in any reasonable expectation. " In West Germany alone, more than three million patients (about 5% of the total population) are constantly taking cardiac glycosides. These drugs are the most prescribed medicaments in many countries. Thus, we considered it worthwhile and necessary to review in a critical way today's knowledge about the foxglove; to report new findings and to evaluate old Statements.

Exocytosis and Endocytosis

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Publisher : Springer Science & Business Media
ISBN 13 : 1588298655
Total Pages : 407 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Exocytosis and Endocytosis by : Andrei I. Ivanov

Download or read book Exocytosis and Endocytosis written by Andrei I. Ivanov and published by Springer Science & Business Media. This book was released on 2008 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, skilled experts provide the most up-to-date, step-by-step laboratory protocols for examining molecular machinery and biological functions of exocytosis and endocytosis in vitro and in vivo. The book is insightful to both newcomers and seasoned professionals. It offers a unique and highly practical guide to versatile laboratory tools developed to study various aspects of intracellular vesicle trafficking in simple model systems and living organisms.

The Enzymes of Biological Membranes

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Publisher : Springer Science & Business Media
ISBN 13 : 1468426583
Total Pages : 461 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Enzymes of Biological Membranes by : Anthony Martonosi

Download or read book The Enzymes of Biological Membranes written by Anthony Martonosi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much of the information currently available on the transport systems of bacterial and animal cell membranes and their mode of coupling to metabolic supply of energy can be found in this volume. Consideration of the participating enzymes dictated the choice of topics: Several transport systems where little information is available on the enzymology of the process are not included, while separate chapters deal with y-glutamyl transpeptidase and intestinal disaccharidases which meet many of the requirements of transport enzymes. The volume also includes two chapters on photosynthetic membranes as a general introduction to the topic. Other aspects of biological transport and photosynthesis will be developed in detail in a forthcoming volume now in preparation. These chapters reveal the excitement and rapid advance of the field, the daily reports of new concepts, new techniques, and new experimental findings which instantly interact to generate further progress. Our aim was to provide a starting point for those who are just beginning, and an opportunity for others to stop, take stock, and start in a new direction. My warmest thanks to all who contributed to this volume.

Regulation of Membrane Na+-K+ ATPase

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Publisher : Springer
ISBN 13 : 3319247506
Total Pages : 434 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Regulation of Membrane Na+-K+ ATPase by : Sajal Chakraborti

Download or read book Regulation of Membrane Na+-K+ ATPase written by Sajal Chakraborti and published by Springer. This book was released on 2015-12-16 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Na+-K+ ATPase or Na-pump ATPase, a member of “P”-type ATPase superfamily, is characterized by association of multiple isoforms mainly of it’s α- and β- subunits. At present four different α- (α-1,α-2,α-3 and α-4) and three β- (β-1, β-2, and β-3) isoforms have been identified in mammalian cells and their differential expressions are tissue specific. Regulation of Na+-K+ ATPase activity is an important but a complex process, which involves short-term and long-term mechanisms. Short-term regulation of Na+-K+ ATPase is either mediated by changes in intracellular Na+ concentrations that directly affect the Na+-pump activity or by phosphorylation/dephosphorylation-mediated by some stimulants leading to changes in its expression and transport properties. On the other hand, long-term regulation of Na+-K+ ATPase is mediated by hormones, such as mineralocorticoids and thyroid hormones, which cause changes in the transcription of genes of α- and β- subunits leading to an increased expression in the level of Na+-pump. Several studies have revealed a relatively new type of regulation that involves the association of small, single span membrane proteins with this enzyme. These proteins belong to the FXYD family, the members of which share a common signature sequence encompassing the transmembra ne domain adjacent to the isoform(s) of α-β subunits of Na+-K+ ATPase. Considering the extraordinary importance of Na+-K+ ATPase in cellular function, several internationally established investigators have contributed their articles in the monograph entitled “Regulation of Membrane Na+-K+ ATPase” for inspiring young scientists and graduate students to enrich their knowledge on the enzyme, and we are sure that this book will soon be considered as a comprehensive scientific literature in the area of Na+-K+ ATPase regulation in health and disease.

The Sodium Pump

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Publisher : Springer Science & Business Media
ISBN 13 : 3642725112
Total Pages : 924 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Sodium Pump by : Ernst Bamberg

Download or read book The Sodium Pump written by Ernst Bamberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 924 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sodium of animal cell membranes converts the chemical energy obtained from the hydrolysis of adenosine 5' -triphosphate into a movement of the cations Na + and K + against an electrochemical gradient. The gradient is used subse quently as an energy source to drive the uptake of metabolic substrates in polar epithelial cells and to use it for purposes of communications in excitable cells. The biological importance of the sodium pump is evident from the fact that be tween 20-70% of the cell's metabolic energy is consumed for the pumping pro cess. Moreover, the sodium pump is an important biological system involved in regulatory processes like the maintenance of the cells' and organism's water me tabolism. It is therefore understandable that special cellular demands are han dled better by special isoforms of the sodium pump, that the expression of the sodium pump and their isoforms is regulated by hormones as is the activity of the sodium pump via hormone-regulated protein kinases. Additionally, the sodium pump itself seems to be a receptor for a putative new group of hormones, the endogenous digitalis-like substances, which still have to be defined in most cases in their structure. This group of substances has its chemically well known coun terpart in steroids from plant and toad origin which are generally known as "car diac glycosides". They are in medical use since at least 200 years in medicine in the treatment of heart diseases.

Biology for AP ® Courses

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Publisher :
ISBN 13 : 9781947172401
Total Pages : 1923 pages
Book Rating : 4.1/5 (724 download)

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Book Synopsis Biology for AP ® Courses by : Julianne Zedalis

Download or read book Biology for AP ® Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

The Na+, K+-pump: Cellular aspects

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Publisher :
ISBN 13 :
Total Pages : 544 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Na+, K+-pump: Cellular aspects by : J. C. Skou

Download or read book The Na+, K+-pump: Cellular aspects written by J. C. Skou and published by . This book was released on 1988 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Insulin Action

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792381136
Total Pages : 206 pages
Book Rating : 4.3/5 (811 download)

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Book Synopsis Insulin Action by : Ashok K. Srivastava

Download or read book Insulin Action written by Ashok K. Srivastava and published by Springer Science & Business Media. This book was released on 1998-05-31 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.

Electrogenic Ion Pumps

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Publisher : Sinauer Associates, Incorporated
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Electrogenic Ion Pumps by : Peter Läuger

Download or read book Electrogenic Ion Pumps written by Peter Läuger and published by Sinauer Associates, Incorporated. This book was released on 1991 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrogenic ion pumps convert chemical, reduction-oxidation, or light energy- into ion concentration differences across all living cells. They are the engines that run cells. In this text, Dr Lunger develops the principles of physical chemistry required to understand the functions of these macromolecules.

Cardiovascular Physiology Concepts

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975150090
Total Pages : 689 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Cardiovascular Physiology Concepts by : Richard E. Klabunde

Download or read book Cardiovascular Physiology Concepts written by Richard E. Klabunde and published by Lippincott Williams & Wilkins. This book was released on 2020-12-01 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praised for its concise coverage, this highly accessible monograph lays a foundation for understanding the underlying concepts of normal cardiovascular function and offers a welcome alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Clear explanations, ample illustrations and engaging clinical cases and problems provide the perfect guidance for self-directed learning and prepare you to excel in clinical practice.

Membrane Structural Biology

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Publisher : Cambridge University Press
ISBN 13 : 1107729335
Total Pages : 427 pages
Book Rating : 4.1/5 (77 download)

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Book Synopsis Membrane Structural Biology by : Mary Luckey

Download or read book Membrane Structural Biology written by Mary Luckey and published by Cambridge University Press. This book was released on 2014-02-24 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.

The Sodium Pump

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Publisher : Rockefeller Univ. Press
ISBN 13 : 9780874700497
Total Pages : 700 pages
Book Rating : 4.7/5 (4 download)

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Book Synopsis The Sodium Pump by : Society of General Physiologists. Symposium

Download or read book The Sodium Pump written by Society of General Physiologists. Symposium and published by Rockefeller Univ. Press. This book was released on 1991 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Electrogenic Transport

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Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Electrogenic Transport by : Mordecai P. Blaustein

Download or read book Electrogenic Transport written by Mordecai P. Blaustein and published by Lippincott Williams & Wilkins. This book was released on 1984 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anatomy and Physiology

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Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Na+, K+ Pumps Keep Us Going

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Publisher :
ISBN 13 : 9788771249392
Total Pages : 0 pages
Book Rating : 4.2/5 (493 download)

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Book Synopsis The Na+, K+ Pumps Keep Us Going by : Torben Clausen

Download or read book The Na+, K+ Pumps Keep Us Going written by Torben Clausen and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every second throughout life, billions of sodium-potassium pumps enable the human muscle cells to function. The pump is an enzyme found in the plasma membrane of all animal cells and is an important example of active transport. The Na, K+-pumps keep us going by pumping sodium out of cells while pumping potassium into cells and without them, we would not survive. Addressed to scientists in the field of biomedicine, the author presents a thorough overview of his scientific results over more than 40 years. The book is richly illustrated and seeks to explain how a single molecule creates the required conditions for our muscles to work.