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The Mird Method Of Estimating Absorbed Dose
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Book Synopsis The MIRD Method of Estimating Absorbed Dose by :
Download or read book The MIRD Method of Estimating Absorbed Dose written by and published by . This book was released on 1991 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: The estimate of absorbed radiation dose from internal emitters provides the information required to assess the radiation risk associated with the administration of radiopharmaceuticals for medical applications. The MIRD (Medical Internal Radiation Dose) system of dose calculation provides a systematic approach to combining the biologic distribution data and clearance data of radiopharmaceuticals and the physical properties of radionuclides to obtain dose estimates. This tutorial presents a review of the MIRD schema, the derivation of the equations used to calculate absorbed dose, and shows how the MIRD schema can be applied to estimate dose from radiopharmaceuticals used in nuclear medicine.
Book Synopsis MIRD Primer for Absorbed Dose Calculations by : Robert Loevinger
Download or read book MIRD Primer for Absorbed Dose Calculations written by Robert Loevinger and published by . This book was released on 1988 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The MIRD Method of Estimating Absorbed Dose by : D.A. Weber
Download or read book The MIRD Method of Estimating Absorbed Dose written by D.A. Weber and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis MIRD: Radionuclide Data and Decay Schemes by : Keith F. Eckerman
Download or read book MIRD: Radionuclide Data and Decay Schemes written by Keith F. Eckerman and published by Snmmi. This book was released on 2007 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiation Dose Estimates for Radiopharmaceuticals by :
Download or read book Radiation Dose Estimates for Radiopharmaceuticals written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Tables of radiation dose estimates based on the Cristy-Eckerman adult male phantom are provided for a number of radiopharmaceuticals commonly used in nuclear medicine. Radiation dose estimates are listed for all major source organs, and several other organs of interest. The dose estimates were calculated using the MIRD Technique as implemented in the MIRDOSE3 computer code, developed by the Oak Ridge Institute for Science and Education, Radiation Internal Dose Information Center. In this code, residence times for source organs are used with decay data from the MIRD Radionuclide Data and Decay Schemes to produce estimates of radiation dose to organs of standardized phantoms representing individuals of different ages. The adult male phantom of the Cristy-Eckerman phantom series is different from the MIRD 5, or Reference Man phantom in several aspects, the most important of which is the difference in the masses and absorbed fractions for the active (red) marrow. The absorbed fractions for flow energy photons striking the marrow are also different. Other minor differences exist, but are not likely to significantly affect dose estimates calculated with the two phantoms. Assumptions which support each of the dose estimates appears at the bottom of the table of estimates for a given radiopharmaceutical. In most cases, the model kinetics or organ residence times are explicitly given. The results presented here can easily be extended to include other radiopharmaceuticals or phantoms.
Book Synopsis A Revised Schema for Calculating the Absorbed Dose from Biologically Distributed Radionuclides by : Robert Loevinger
Download or read book A Revised Schema for Calculating the Absorbed Dose from Biologically Distributed Radionuclides written by Robert Loevinger and published by . This book was released on 1976 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fundamentals of Nuclear Medicine Dosimetry by : Michael G. Stabin
Download or read book Fundamentals of Nuclear Medicine Dosimetry written by Michael G. Stabin and published by Springer Science & Business Media. This book was released on 2008-01-15 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leading international authority in the field, this book is ideal for physicians and residents in nuclear medicine who want to improve their knowledge in internal dosimetry. The text is a practical introduction that guides the reader through fundamental concepts in the calculation of radiation dose, including discussions of standardized models, methods of calculations, and available software applications. This comprehensive guide discusses too the biological effects of radiation on living systems. The book also includes an overview of regulatory aspects related to the radiation dosimetry of new radiopharmaceuticals.
Book Synopsis Biologic Data, Models, and Dosimetric Methods for Internal Emitters by :
Download or read book Biologic Data, Models, and Dosimetric Methods for Internal Emitters written by and published by . This book was released on 1990 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: The absorbed radiation dose from internal emitters has been and will remain a pivotal factor in assessing risk and therapeutic utility in selecting radiopharmaceuticals for diagnosis and treatment. Although direct measurements of absorbed dose and dose distributions in vivo have been and will continue to be made in limited situations, the measurement of the biodistribution and clearance of radiopharmaceuticals in human subjects and the use of this data is likely to remain the primary means to approach the calculation and estimation of absorbed dose from internal emitters over the next decade. Since several approximations are used in these schema to calculate dose, attention must be given to inspecting and improving the application of this dosimetric method as better techniques are developed to assay body activity and as more experience is gained in applying these schema to calculating absorbed dose. Discussion of the need for considering small scale dosimetry to calculate absorbed dose at the cellular level will be presented in this paper. Other topics include dose estimates for internal emitters, biologic data mathematical models and dosimetric methods employed. 44 refs.
Book Synopsis Radiation Oncology Physics by : International Atomic Energy Agency
Download or read book Radiation Oncology Physics written by International Atomic Energy Agency and published by IAEA. This book was released on 2005 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is aimed at students and teachers involved in teaching programmes in field of medical radiation physics, and it covers the basic medical physics knowledge required in the form of a syllabus for modern radiation oncology. The information will be useful to those preparing for professional certification exams in radiation oncology, medical physics, dosimetry or radiotherapy technology.
Book Synopsis Dosimetry for Radiopharmaceutical Therapy by : IAEA
Download or read book Dosimetry for Radiopharmaceutical Therapy written by IAEA and published by International Atomic Energy Agency. This book was released on 2024-04-30 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this publication the basic principles of radiation physics, imaging and non-imaging instrumentation used, measurement of the administered activity, calibration procedures and methods for obtaining quantitative information on the biodistribution of the radioactive drug to be used with radioisotopes relevant to therapy are specified. It also describes methods for segmentation and registration of images acquired at different time points, strategies for fitting and integration of activity measurements over the time of treatment, absorbed dose calculations and derived dosimetric indexes with methods to estimate the overall uncertainty of different radionuclide therapies. The aim of this book is to fill the existing gaps in education and training of medical physicists on methods for patient-specific dosimetry. The overall objective of this book is to highlight the tools and methodologies to assure that radiopharmaceutical therapy is implemented through a dosimetry-guided individualized treatment approach.
Book Synopsis MIRD Cellular S. Values by : S. Murty Goddu
Download or read book MIRD Cellular S. Values written by S. Murty Goddu and published by Society of Nuclear Medicine, Incorporated. This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Toxicological Risk Assessment and Multi-System Health Impacts from Exposure by : Aristidis M. Tsatsakis
Download or read book Toxicological Risk Assessment and Multi-System Health Impacts from Exposure written by Aristidis M. Tsatsakis and published by Elsevier. This book was released on 2021-08-01 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. - Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field - Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease - Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research
Book Synopsis Physics for Clinical Oncology by : Amen Sibtain
Download or read book Physics for Clinical Oncology written by Amen Sibtain and published by Oxford University Press. This book was released on 2022-11-24 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiotherapy remains a major non-surgical treatment modality for malignant disease, and an understanding of how this treatment works is essential in ensuring optimum practice. Trainees in oncology learn about ionising radiation, but to understand it fully they must also understand the physics relevant to its use in therapy. This book is written specifically for the oncology and radiation team, supporting clinical oncologists in their understanding of the science which underpins radiotherapy. It begins with basic concepts and then explores the principles and practice of physics as it relates to radiotherapy, including discussion of specific types of therapy. Written by authors chosen for their expertise in in their respective fields, and aligned to the Royal College of Radiologists FRCR Curriculum in Oncology, this volume will provide an excellent source of information for trainee and practicing oncologists, and wider radiotherapy teams. This second edition has been fully updated to reflect advances in technology and the increased complexity in modern radiotherapy, including two new chapters on imaging and a new brachytherapy chapter.
Book Synopsis Radiation Dosimetry Instrumentation and Methods by : Gad Shani
Download or read book Radiation Dosimetry Instrumentation and Methods written by Gad Shani and published by CRC Press. This book was released on 2000-12-28 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation dosimetry has made great progress in the last decade, mainly because radiation therapy is much more widely used. Since the first edition, many new developments have been made in the basic methods for dosimetry, i.e. ionization chambers, TLD, chemical dosimeters, and photographic films. Radiation Dosimetry: Instrumentation and Methods, Second Edition brings to the reader these latest developments. Written at a high level for medical physicists, engineers, and advanced dosimetrists, it concentrates only on evolvement during the last decade, relying on the first edition to provide the basics.
Author :Committee on Risk Assessment of Exposure to Radon in Drinking Water Publisher :National Academies Press ISBN 13 :0309524741 Total Pages :294 pages Book Rating :4.3/5 (95 download)
Book Synopsis Risk Assessment of Radon in Drinking Water by : Committee on Risk Assessment of Exposure to Radon in Drinking Water
Download or read book Risk Assessment of Radon in Drinking Water written by Committee on Risk Assessment of Exposure to Radon in Drinking Water and published by National Academies Press. This book was released on 1999-07-08 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Safe Drinking Water Act directs the U.S. Environmental Protection Agency (EPA) to regulate the quality of drinking water, including its concentration of radon, an acknowledged carcinogen. This book presents a valuable synthesis of information about the total inhalation and ingestion risks posed by radon in public drinking water, including comprehensive reviews of data on the transfer of radon from water to indoor air and on outdoor levels of radon in the United States. It also presents a new analysis of a biokinetic model developed to determine the risks posed by ingestion of radon and reviews inhalation risks and the carcinogenesis process. The volume includes scenarios for quantifying the reduction in health risk that might be achieved by a program to reduce public exposure to radon. Risk Assessment of Radon in Drinking Water, reflecting research and analysis mandated by 1996 amendments to the Safe Drinking Water Act, provides comment on a variety of methods to reduce radon entry into homes and to reduce the concentrations of radon in indoor air and in water. The models, analysis, and reviews of literature contained in this book are intended to provide information that EPA will need to set a new maximum contaminant level, as it is required to do in 2000.
Book Synopsis Introduction to Radiological Physics and Radiation Dosimetry by : Frank Herbert Attix
Download or read book Introduction to Radiological Physics and Radiation Dosimetry written by Frank Herbert Attix and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: A straightforward presentation of the broad concepts underlying radiological physics and radiation dosimetry for the graduate-level student. Covers photon and neutron attenuation, radiation and charged particle equilibrium, interactions of photons and charged particles with matter, radiotherapy dosimetry, as well as photographic, calorimetric, chemical, and thermoluminescence dosimetry. Includes many new derivations, such as Kramers X-ray spectrum, as well as topics that have not been thoroughly analyzed in other texts, such as broad-beam attenuation and geometrics, and the reciprocity theorem. Subjects are layed out in a logical sequence, making the topics easier for students to follow. Supplemented with numerous diagrams and tables.
Book Synopsis Novel Designs of Early Phase Trials for Cancer Therapeutics by : Shivaani Kummar
Download or read book Novel Designs of Early Phase Trials for Cancer Therapeutics written by Shivaani Kummar and published by Academic Press. This book was released on 2018-05-22 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials. Brings a comprehensive review and recommendations for new clinical trial designs for modern cancer therapeutics Provides the reader with a better understanding on how to design and implement early phase oncology trials Presents a better and updated understanding of the process of developing new treatments for cancer, the exciting scientific advances and how they are informing drug development
