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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eric Bertrand
Publisher : Springer Science & Business Media
ISBN 13 : 1402059434
Total Pages : 397 pages
Book Rating : 4.4/5 (2 download)
Download or read book Subcellular Proteomics written by Eric Bertrand and published by Springer Science & Business Media. This book was released on 2007-08-29 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes the new developments that made subcellular proteomics a rapidly expanding area. It examines the different levels of subcellular organization and their specific methodologies. In addition, the book includes coverage of systems biology that deals with the integration of the data derived from these different levels to produce a synthetic description of the cell as a system.
Author : Gene I. Sher
Publisher : Springer Science & Business Media
ISBN 13 : 1461444632
Total Pages : 836 pages
Book Rating : 4.4/5 (614 download)
Download or read book Handbook of Neuroevolution Through Erlang written by Gene I. Sher and published by Springer Science & Business Media. This book was released on 2012-11-06 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Neuroevolution Through Erlang presents both the theory behind, and the methodology of, developing a neuroevolutionary-based computational intelligence system using Erlang. With a foreword written by Joe Armstrong, this handbook offers an extensive tutorial for creating a state of the art Topology and Weight Evolving Artificial Neural Network (TWEANN) platform. In a step-by-step format, the reader is guided from a single simulated neuron to a complete system. By following these steps, the reader will be able to use novel technology to build a TWEANN system, which can be applied to Artificial Life simulation, and Forex trading. Because of Erlang’s architecture, it perfectly matches that of evolutionary and neurocomptational systems. As a programming language, it is a concurrent, message passing paradigm which allows the developers to make full use of the multi-core & multi-cpu systems. Handbook of Neuroevolution Through Erlang explains how to leverage Erlang’s features in the field of machine learning, and the system’s real world applications, ranging from algorithmic financial trading to artificial life and robotics.
Author : Jesus Avila
Publisher : Frontiers E-books
ISBN 13 : 288919261X
Total Pages : 114 pages
Book Rating : 4.8/5 (891 download)
Download or read book Tau oligomers written by Jesus Avila and published by Frontiers E-books. This book was released on 2014-08-18 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.
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Publisher :
ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Publisher : Elsevier
ISBN 13 : 0080538495
Total Pages : 273 pages
Book Rating : 4.0/5 (85 download)
Download or read book Pathobiology of Alzheimer's Disease written by and published by Elsevier. This book was released on 1995-10-17 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.The last decade has seen tremendous advances in our understanding of the pathobiology of Alzheimer's disease. These will lead to the first generation of drugs aimed at prevention rather than cure. This book covers some of the most important and exciting of these advances, with chapters written by many of the leading researchers in the field.With genetic studies as a backbone to this volume many chapters are devoted to the function and regulation of amyloid b-protein precursor (APP) and apolipoprotein E (ApoE). Other chapters describe cell biological approaches helping to piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease.Although APP and its proteolytic cleavage product, amyloid b-protein, do not answer all the questions, detailed research into this system has undoubtedly increased our knowledge of the pathobiology of AD and has lead to the identification of other risk factors. Understanding the role of ApoE in the pathology of Alzheimer's disease promises to open a whole new field in AD research.* * Reviews the current knowledge of the pathogenesis of Alzheimer's Disease from a clinical perspective to a genetic and cell biological perspective* A comprehensive description of the role of amyloid B-protein precursor in Alzheimer's disease.* Up-to-date research data* Clear illustrations complement the text
Author : British Theses Service
Publisher :
ISBN 13 :
Total Pages : 1156 pages
Book Rating : 4.3/5 (91 download)
Download or read book The BRITS Index: Subject index written by British Theses Service and published by . This book was released on 1989 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Peter Ghosh
Publisher : CRC Press
ISBN 13 : 1000006441
Total Pages : 256 pages
Book Rating : 4.0/5 ( download)
Download or read book Biology Of Invertebral Disc written by Peter Ghosh and published by CRC Press. This book was released on 2019-06-04 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1988, this book documents the role, biology, and structure of the Intervertebral Disc. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Medicine, Chiropractors, and other practitioners in their respective fields.
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Publisher :
ISBN 13 :
Total Pages : 1330 pages
Book Rating : 4.3/5 (91 download)
Download or read book Current Bibliography of Epidemiology written by and published by . This book was released on 1972 with total page 1330 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : L. S. Hnilica
Publisher : CRC Press
ISBN 13 : 1351079115
Total Pages : 265 pages
Book Rating : 4.3/5 (51 download)
Download or read book Chromosomal Nonhistone Protein written by L. S. Hnilica and published by CRC Press. This book was released on 2018-12-17 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third volume of the Chromosomal Nonhistone Proteins treatise deals with the isolation and analysis of chromosomal proteins in general with specific features of these proteins in particular. In addition to the high mobility group (HMG) proteins, post synthetic modifications of chromosomal nonhistone proteins are discussed, together with some of their enzymatic properties DNA binding.
Author : Shohreh Amini
Publisher : Humana
ISBN 13 : 9781071614396
Total Pages : 205 pages
Book Rating : 4.6/5 (143 download)
Download or read book Neuronal Cell Culture written by Shohreh Amini and published by Humana. This book was released on 2022-06-09 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition volume details the latest aspects of neural cells covering the practical and theoretical considerations of each techniques involved. Chapters guide readers through a general overview of the neuronal culturing principles, cell line models for neural cells, the isolation and propagation of primary cultures, stem cells, transfection and transduction of neural cultures, and other more advanced techniques. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and easy to use, Neuronal Cell Culture: Methods and Protocols, Second Edition aims to be of interest to scientists at all levels studying cell culture models for neuroscientific studies.
Author : H. Peeters
Publisher : Elsevier
ISBN 13 : 1483148386
Total Pages : 525 pages
Book Rating : 4.4/5 (831 download)
Download or read book Protides of the Biological Fluids written by H. Peeters and published by Elsevier. This book was released on 2013-10-02 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protides of the Biological Fluids examines protides of the biological fluids and covers topics ranging from the use of DNA probes to diagnose inherited diseases and receptors to the conformation and function of biologically active peptides. This text has 115 chapters and begins by demonstrating the existence of gene families common to several vertebrates and which evolved by intragenic duplication. The chapters that follow focus on the use of DNA probes in the analysis of inherited disorders such as thalassemia and hemophilia. The reader is then introduced to receptors, especially for peptides. Receptors on circulating cells, hormone receptors, receptors involved in cancer, and immunoglobulin receptors are explored. The section on the conformation and function of biologically active peptides considers the methods including spectroscopic methods, crystallography, and theoretical conformational analysis. In particular, the use of synchrotron X-radiation in biological crystallography and of 2D NMR spectroscopy in the identification of folded structures in immunogenic peptides is highlighted. This book will be of value to biologists and biochemists.
Author :
Publisher :
ISBN 13 :
Total Pages : 1104 pages
Book Rating : 4.3/5 (91 download)
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1991 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roger Harrison
Publisher : Routledge
ISBN 13 : 1351421018
Total Pages : 398 pages
Book Rating : 4.3/5 (514 download)
Download or read book Protein Purification Process Engineering written by Roger Harrison and published by Routledge. This book was released on 2019-07-16 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers coverage of the development of protein purification processes for large-scale commercial operations, and addresses process development, scale-up, applications and mathematical descriptions. Technologies currently used at the commercial scale are covered in depth.
Author :
Publisher :
ISBN 13 :
Total Pages : 184 pages
Book Rating : 4.:/5 (327 download)
Download or read book AIDS Bibliography written by and published by . This book was released on 1995-06 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 1780 pages
Book Rating : 4.:/5 (319 download)
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1780 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author : National Heart, Lung, and Blood Institute
Publisher :
ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.3/5 ( download)
Download or read book Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute written by National Heart, Lung, and Blood Institute and published by . This book was released on 1979 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:
