The Human Genome Project and the Future of Health Care

Download The Human Genome Project and the Future of Health Care PDF Online Free

Author :
Publisher : Indiana University Press
ISBN 13 : 9780253113252
Total Pages : 266 pages
Book Rating : 4.1/5 (132 download)

DOWNLOAD NOW!


Book Synopsis The Human Genome Project and the Future of Health Care by : Thomas H. Murray

Download or read book The Human Genome Project and the Future of Health Care written by Thomas H. Murray and published by Indiana University Press. This book was released on 1996-12-22 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The volume deserves our serious attention. The authors have provided us an invaluable primer about the HGP and its implications for the future of American health care." -- Jurimetrics "This book does make a real contribution... in explaining why the genetics revolution holds so much promise and why it is so difficult to bring that promise to fruition." -- The Journal of Legal Medicine "... marked by a forward-looking, analytically and empirically grounded thematic coherence. The editors' carefully crafted template and contributions successfully focus and organize the material." -- Annals of Internal Medicine "Excellent" -- Canadian Medical Association Journal "The editors have done a very good job integrating the contents into a very useful and readable information source." -- Choice "... this highly focused book is a well-written, thoughtful, and insightful consideration of the HGP and is valuable reading for anyone concerned with the future of our country's medical infrastructure." -- Science Books & Films (**Highly recommended) "A distinguished group of scientists, lawyers, and scholars have written a coherent, readable account of the legal, medical, ethical, and policy issues many (if not all) of us will be wrestling with on both a personal and a public level, as a result of current genetic research." -- Library Journal "Each of the contributors is a distinguished authority on the topic. Ethicists, especially, will find well-developed presentation of issues, with exposition of the differing ethical assumptions in tension in the society debate." -- Doody's Health Sciences Book Review Home Page How will the science of gene mapping and gene manipulation affect health care? Leading scholars explore the clinical, ethical, legal, and policy implications of the Human Genome Project for the forms of health care, who delivers it, who receives it, and who pays for it.

Technology and the Future of Health Care

Download Technology and the Future of Health Care PDF Online Free

Author :
Publisher : Jossey-Bass
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.:/5 ( download)

DOWNLOAD NOW!


Book Synopsis Technology and the Future of Health Care by : David Ellis

Download or read book Technology and the Future of Health Care written by David Ellis and published by Jossey-Bass. This book was released on 2001-03-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most experts believe that innovation in every aspect of patient care will be nothing less than astonishing as we move into the next century. Technology and the Future of Health Care brings together a remarkable group of health care visionaries who have identified and begun to analyze which trends and technological advances will likely shape and inform the next generation of medicine. From fundamental advances in computing and administration, research, nursing, and patient care delivery to noninvasive surgery, biomolecular therapies, bionics, and beyond, this ground-breaking book offers professional, executive-level insight into topics that until recently existed only in the realm of science fiction.

Mapping and Sequencing the Human Genome

Download Mapping and Sequencing the Human Genome PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Justice and the Human Genome Project

Download Justice and the Human Genome Project PDF Online Free

Author :
Publisher : Univ of California Press
ISBN 13 : 0520377931
Total Pages : 195 pages
Book Rating : 4.5/5 (23 download)

DOWNLOAD NOW!


Book Synopsis Justice and the Human Genome Project by : Timothy F. Murphy

Download or read book Justice and the Human Genome Project written by Timothy F. Murphy and published by Univ of California Press. This book was released on 2024-07-26 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Human Genome Project is an expensive, ambitious, and controversial attempt to locate and map every one of the approximately 100,000 genes in the human body. If it works, and we are able, for instance, to identify markers for genetic diseases long before they develop, who will have the right to obtain such information? What will be the consequences for health care, health insurance, employability, and research priorities? And, more broadly, how will attitudes toward human differences be affected, morally and socially, by the setting of a genetic “standard”? The compatibility of individual rights and genetic fairness is challenged by the technological possibilities of the future, making it difficult to create an agenda for a “just genetics.” Beginning with an account of the utopian dreams and authoritarian tendencies of historical eugenics movements, this book’s nine essays probe the potential social uses and abuses of detailed genetic information. Lucid and wide-ranging, these contributions will interest bioethicists, legal scholars, and policy makers. Essays: “The Genome Project and the Meaning of Difference,” Timothy F. Murphy “Eugenics and the Human Genome Project: Is the Past Prologue?,” Daniel J. Kevles “Handle with Care: Race, Class, and Genetics,” Arthur L. Caplan “Public Choices and Private Choices: Legal Regulation of Genetic Testing,” Lori B. Andrews “Rules for Gene Banks: Protecting Privacy in the Genetics Age,” George J. Annas “Use of Genetic Information by Private Insurers,” Robert J. Pokorski “The Genome Project, Individual Differences, and Just Health Care,” Norman Daniels “Just Genetics: A Problem Agenda,” Leonard M. Fleck “Justice and the Limitations of Genetic Knowledge,” Marc A. Lappé This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1994.

Genomic and Personalized Medicine

Download Genomic and Personalized Medicine PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0123822270
Total Pages : 1343 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!


Book Synopsis Genomic and Personalized Medicine by : Geoffrey S. Ginsburg

Download or read book Genomic and Personalized Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2012-11-29 with total page 1343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Personalized Medicine, Second Edition - winner of a 2013 Highly Commended BMA Medical Book Award for Medicine - is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003. Highly Commended 2013 BMA Medical Book Award for Medicine More than 100 chapters, from leading researchers, review the many impacts of genomic discoveries in clinical action, including 63 chapters new to this edition Discusses state-of-the-art genome technologies, including population screening, novel diagnostics, and gene-based therapeutics Wide and inclusive discussion encompasses the formidable ethical, legal, regulatory and social challenges related to the evolving practice of genomic medicine Clearly and beautifully illustrated with 280 color figures, and many thousands of references for further reading and deeper analysis

The Future of the Public's Health in the 21st Century

Download The Future of the Public's Health in the 21st Century PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309133181
Total Pages : 536 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis The Future of the Public's Health in the 21st Century by : Institute of Medicine

Download or read book The Future of the Public's Health in the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2003-02-01 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The anthrax incidents following the 9/11 terrorist attacks put the spotlight on the nation's public health agencies, placing it under an unprecedented scrutiny that added new dimensions to the complex issues considered in this report. The Future of the Public's Health in the 21st Century reaffirms the vision of Healthy People 2010, and outlines a systems approach to assuring the nation's health in practice, research, and policy. This approach focuses on joining the unique resources and perspectives of diverse sectors and entities and challenges these groups to work in a concerted, strategic way to promote and protect the public's health. Focusing on diverse partnerships as the framework for public health, the book discusses: The need for a shift from an individual to a population-based approach in practice, research, policy, and community engagement. The status of the governmental public health infrastructure and what needs to be improved, including its interface with the health care delivery system. The roles nongovernment actors, such as academia, business, local communities and the media can play in creating a healthy nation. Providing an accessible analysis, this book will be important to public health policy-makers and practitioners, business and community leaders, health advocates, educators and journalists.

Molecular Medicine

Download Molecular Medicine PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0123814529
Total Pages : 347 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!


Book Synopsis Molecular Medicine by : R.J. Trent

Download or read book Molecular Medicine written by R.J. Trent and published by Academic Press. This book was released on 2012-08-22 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances. - Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine - The only book in Molecular Medicine to reach its fourth edition - Identifies current practice as well as future developments - Presents extensive tables, well presented figures and resources for further understanding

The Genome Odyssey

Download The Genome Odyssey PDF Online Free

Author :
Publisher : Celadon Books
ISBN 13 : 1250234972
Total Pages : 221 pages
Book Rating : 4.2/5 (52 download)

DOWNLOAD NOW!


Book Synopsis The Genome Odyssey by : Dr. Euan Angus Ashley

Download or read book The Genome Odyssey written by Dr. Euan Angus Ashley and published by Celadon Books. This book was released on 2021-02-23 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

Medical and Health Genomics

Download Medical and Health Genomics PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0127999221
Total Pages : 360 pages
Book Rating : 4.1/5 (279 download)

DOWNLOAD NOW!


Book Synopsis Medical and Health Genomics by : Dhavendra Kumar

Download or read book Medical and Health Genomics written by Dhavendra Kumar and published by Academic Press. This book was released on 2016-06-04 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. - Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management - Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study - Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management - Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

The Age of Scientific Wellness

Download The Age of Scientific Wellness PDF Online Free

Author :
Publisher : Harvard University Press
ISBN 13 : 0674245946
Total Pages : 353 pages
Book Rating : 4.6/5 (742 download)

DOWNLOAD NOW!


Book Synopsis The Age of Scientific Wellness by : Leroy Hood

Download or read book The Age of Scientific Wellness written by Leroy Hood and published by Harvard University Press. This book was released on 2023-04-04 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking us to the cutting edge of the new frontier of medicine, a visionary biotechnologist and a pathbreaking researcher show how we can optimize our health in ways that were previously unimaginable. We are on the cusp of a paradigm shift in the delivery of health care as major diseases are being challenged in fresh and unexpected ways. Using predictive technologies, applied immunotherapy, and genomically informed disease prevention, scientists are working closely with patients to dramatically extend their "healthspan"--the number of healthy years before disease sets in. Leroy Hood, whose innovations made possible the sequencing of the human genome, and Nathan Price, whose work on systems biology is opening new pathways to Alzheimer's treatment and prevention, take us on a thrilling journey to this new frontier of medicine. Today, most doctors wait for clinical symptoms to appear before they act. Countless patients are prescribed medication and subjected to invasive procedures from which they derive no benefit. We must move beyond this reactive, hit-or-miss approach to usher in real precision care or "scientific wellness." Fusing information gleaned from our personal genomic profiles with data drawn from our blood, microbiomes, and hundreds of other inputs, all analyzed by artificial intelligence, doctors can detect the early onset of disease decades before symptoms arise, revolutionizing prevention. Current applications have already shown startling results: Alzheimer's held back, cancers found early and eliminated, diabetes avoided, and autoimmune diseases neutralized. Genomically informed medicine is not some future fantasy: it is already happening at top medical centers, but only for a narrow band of diseases and only once they are well advanced. This book shares the insights of this exciting new science to help you chart a course to a longer, healthier life.

The Human Genome Project in College Curriculum

Download The Human Genome Project in College Curriculum PDF Online Free

Author :
Publisher : UPNE
ISBN 13 : 9781584656951
Total Pages : 206 pages
Book Rating : 4.6/5 (569 download)

DOWNLOAD NOW!


Book Synopsis The Human Genome Project in College Curriculum by : Aine Donovan

Download or read book The Human Genome Project in College Curriculum written by Aine Donovan and published by UPNE. This book was released on 2008 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Begun formally in 1990, the U.S. Human Genome Project's (HGP) goals were to identify all the 20,000 to 25,000 genes in human DNA, determine the sequences of the three billion chemical base pairs that make up human DNA, store this information in databases, improve tools for data analysis, and transfer related technologies to the private sector. It was the first large scientific undertaking to address potential issues that arose from project data, and opened up vast possibilities for the use of genetic data and the alteration of our genetic makeup. This volume is the first to address the diverse range of ethical issues arising from the HGP, and enables professors to bring this critically important topic to life in the classroom. ';

Genomics and the Reimagining of Personalized Medicine

Download Genomics and the Reimagining of Personalized Medicine PDF Online Free

Author :
Publisher : Routledge
ISBN 13 : 1317129393
Total Pages : 212 pages
Book Rating : 4.3/5 (171 download)

DOWNLOAD NOW!


Book Synopsis Genomics and the Reimagining of Personalized Medicine by : Richard Tutton

Download or read book Genomics and the Reimagining of Personalized Medicine written by Richard Tutton and published by Routledge. This book was released on 2016-04-15 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on insights from work in medical history and sociology, this book analyzes changing meanings of personalized medicine over time, from the rise of biomedicine in the twentieth century, to the emergence of pharmacogenomics and personal genomics in the 1990s and 2000s. In the past when doctors championed personalization they did so to emphasize that patients had unique biographies and social experiences in the name of caring for their patients as individuals. However, since the middle of the twentieth century, geneticists have successfully promoted the belief that genes are implicated in why some people develop diseases and why some have adverse reactions to drugs when others do not. In doing so, they claim to offer a new way of personalizing the prediction, prevention and treatment of disease. As this book shows, the genomic reimagining of personalized medicine centres on new forms of capitalization and consumption of genetic information. While genomics promises the ultimate individualization of medicine, the author argues that personalized medicine exists in the imaginative gap between the problems and limits of current scientific practices and future prospects to individualize medical interventions. A rigorous, critical examination of the promises of genomics to transform the economics and delivery of medicine, Genomics and the Reimagining of Personalized Medicine examines the consequences of the shift towards personalization for the way we think about and act on health and disease in society. As such, it will be of interest to scholars and students of the sociology of medicine and health, science and technology studies, and health policy.

The Human Genome Project

Download The Human Genome Project PDF Online Free

Author :
Publisher :
ISBN 13 : 9781435803268
Total Pages : 64 pages
Book Rating : 4.8/5 (32 download)

DOWNLOAD NOW!


Book Synopsis The Human Genome Project by : James Toriello

Download or read book The Human Genome Project written by James Toriello and published by . This book was released on 2009-01-01 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ripped from Today's Headlines, Here Are Six Important Titles Focusing on the Future of Medical Technology This series of books highlights current and future trends in advancing medical technology, from the use of new materials for artificial organs to the genetic engineering of disease-free human beings. New diagnostic imaging systems have made it much easier for doctors to determine the nature of injuries, and new surgical tools mean safer operations and shorter stays in the hospital. Future medicine will likely astound us all. This book tells of the discovery of the genetic sequences of human DNA and what that discovery may mean for treating or eliminating genetically-linked diseases. Also discussed are some of the ethical issues surrounding the use of this technology.

The Genetics Revolution

Download The Genetics Revolution PDF Online Free

Author :
Publisher : Bloomsbury Publishing USA
ISBN 13 : 0313059861
Total Pages : 232 pages
Book Rating : 4.3/5 (13 download)

DOWNLOAD NOW!


Book Synopsis The Genetics Revolution by : Rose Morgan

Download or read book The Genetics Revolution written by Rose Morgan and published by Bloomsbury Publishing USA. This book was released on 2005-11-30 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: What will our lives be like fifty years from now? What will we know about ourselves as humans, and how will that affect our lives? It's impossible to know the future for certain, but one thing we do know—perhaps nothing will alter our future more than the Genetics Revolution of the past thirty-five years. This book clarifies the history and examines the possible impact of five major areas of genetic research: The Human Genome Project and genetic engineering, In vitro fertilization (IVF) and the technology of reproduction, The Human Genome Diversity Project, which is studying the variation of the human genome, Embryonic stem-cell research, Cloning. All of these areas of research produce two reactions among the general public—hope for the improvement of people's lives, and fear of science out of control. The Genetics Revolution examines the scientific, social, and political impacts of the genetics on everyday life—in the past, in the present, and in the future. Each specific topic is contained within its own chapter for ease in accessing specific information. This is an ideal resource for students, teachers, and others preparing research papers. In addition, it integrates science and social science topics in a way that supports topics in the school curricula. The book contains documented, current information that both supports and challenges current thinking about genetics.

Access to the Genome

Download Access to the Genome PDF Online Free

Author :
Publisher : Georgetown University Press
ISBN 13 : 9781589012295
Total Pages : 164 pages
Book Rating : 4.0/5 (122 download)

DOWNLOAD NOW!


Book Synopsis Access to the Genome by : Maxwell J. Mehlman

Download or read book Access to the Genome written by Maxwell J. Mehlman and published by Georgetown University Press. This book was released on 1998-01-01 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completion of the Human Genome Project will make possible a staggering array of new medical technologies, including new diagnostic and screening tests for inherited disorders, gene therapies, and the ability to manipulate a person's inherited, non-disease traits. Most of the attention given to the social implications of these technologies has focused on their potential to harm the individual, for example, by denying employment or insurance. This book explores instead the potential harm to society if we unfairly distribute the enormous benefits of genetic technologies. The resulting division of society into genetic haves and have-nots would undermine the basic foundation of Western democratic society—the belief in equality of opportunity. This book explains, in terms that can be understood by the general reader, how DNA works, what the Human Genome Project is, what these genetic technologies are and what they promise, and how they could disrupt our democratic society. In an original contribution to the literature, the book then discusses the alternatives for avoiding the creation of a genetic underclass, ranging from halting the Human Genome Project itself to making genetic technologies available without regard to ability to pay. The authors' provocative conclusion is that a lottery in which everyone has a chance to obtain access to these technologies is the only feasible option. This book will be of interest to anyone who wishes to learn more about the Human Genome Project and the genetic revolution that it will create, as well as those who already are familiar with the project and are concerned about the social consequences of its scientific developments.

Here Is a Human Being

Download Here Is a Human Being PDF Online Free

Author :
Publisher : Harper Collins
ISBN 13 : 0062010468
Total Pages : 356 pages
Book Rating : 4.0/5 (62 download)

DOWNLOAD NOW!


Book Synopsis Here Is a Human Being by : Misha Angrist

Download or read book Here Is a Human Being written by Misha Angrist and published by Harper Collins. This book was released on 2010-11-02 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a Human Being delivers the first in-depth look at the Personal Genome Project—the effort to construct complete genomic maps of a specific human beings—written by one of the study’s ten human participants. Misha Angrist recounts the project’s fascinating nuances, including the larger-than-life personalities of the research subjects, the entrepreneurial scientists at the helm, the bewildered and overwhelmed physicians and regulators who negotiated for it, the fascinating technology it employed, and the political, social, ethical and familial issues it continues to raise. In the vein of James Shreeve’s The Genome War, Craig J. Ventner’s My Life Decoded, and Francis J. Collins’ The Language of Life, Angrist’s informed exploration of this cutting-edge science is a gripping look at the present and future of genomics.

Heritable Human Genome Editing

Download Heritable Human Genome Editing PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309671132
Total Pages : 239 pages
Book Rating : 4.3/5 (96 download)

DOWNLOAD NOW!


Book Synopsis Heritable Human Genome Editing by : The Royal Society

Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.